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Relationship between Depression and Laryngopharyngeal Reflux
주영훈,송윤수,배치운 대한신경정신의학회 2017 PSYCHIATRY INVESTIGATION Vol.14 No.2
This study investigated the relationship between depression, somatization, anxiety, personality, and laryngopharyngeal reflux (LPR). We prospectively analyzed 231 patients with symptoms with LPR using the laryngopharyngeal reflux symptom index and the reflux finding score. Seventy nine (34.2%) patients were diagnosed with LPR. A significant correlation was detected between the presence of LPR and total scores on the Patient Health Questionnaire-9 (5.6±5.3 vs. 4.0±4.6, p=0.017) and the 7-item Generalized Anxiety Disorder Scale (4.3±4.9 vs. 3.0±4.5, p=0.041). LPR was significantly more frequent in those with depression than in those without (45.6% vs. 27.0%, p=0.004). A multivariate analysis confirmed a significant association between the presence of LPR and depression (odds ratio, 1.068; 95% confidence interval, 1.011–1.128; p=0.019). Our preliminary results suggest that patients with LPR may need to be carefully evaluated for depression.
김정석,김성관,김진호,송윤수,윤영대,이다인,이솔,조규연,조다연,조연경,진문석,유근창 대한시과학회 2017 대한시과학회지 학술대회 Vol.2017 No.06
목적: 본 연구는 –2.00D 이하의 난시를 가진 사람에게 콘택트렌즈 처방 시 구면등가대등법에 의한 구면 콘택트렌즈가 토릭 콘택트렌즈와 비교하여 시력, 자각적 만족도의 차이가 어느 정도인지 확인하고자 하였다. 방법: 전신질환 및 안과적 수술경험이 없고 실험의 취지를 이해하고 동의한 교정시력 1.0 이상의 남녀 6명을 대상으로 하였다. 구면과 토릭콘택트렌즈는 동일한 재질과 베이스커브의 콘택트렌즈를 사용하였으며, 콘택트렌즈 피팅을 위해 문진, 전안부검사, 각막곡률검사, 굴절검사, 피팅 평가 등을 실시한 후 교정시력과 착용 후 자각적 만족도(건조감, 이물감, 흐림, 눈부심, 두통, 가려움증, 충혈 등) 조사를 실시하였다. 결과: 난시도수에 따라 그룹A(-1.00D 미만), 그룹B(-1.00D ~ -2.00D)으로 나누어 등가구 면콘택트렌즈 처방결과 착용 시간이 길어짐에 따라 시력교정에 대한 만족도 낮았으나, 토릭 소프트콘택트렌즈의 경우 착용 시간에 상관없이 만족도가 매우 높게 조사되었다. 또한 등가 구면 콘택트렌즈의 처방 교정시력은 그룹 A(난시도수 -1.00D미만)의 경우 교정시력의 만족 도가 낮게 나타났으며, 그룹 B(난시도수 -1.00D~-2.00D)의 처방 교정시력에서는 등가구 면 처방된 콘택트렌즈에 비해 시력 향상과 높은 만족도를 보였다. 결론: 두 그룹 모두 구면 소프트콘택트렌즈와 토릭 소프트콘택트렌즈에서 시력향상에 유의한 차이를 보였으나, 자각적 만족도를 함께 비교한 결과 토릭 소프트콘택트렌즈를 처방할 경우 시력 향상과 안정피로 개선에 도움이 되기 때문에 난시 콘택트렌즈처방에서 토릭 소프트콘택트렌즈를 처방이 우선되어야 할 것으로 생각된다.
풀빅산의 돼지 음수 투여 및 양돈장 분무가 냄새 저감에 미치는 영향
배수연 ( Su Yeon Bae ),송윤수 ( Yoon Soo Song ),이상락 ( Sang Rak Lee ),김법균 ( Beob Gyun Kim ),송준익 ( Jun Ik Song ) 한국축산학회 2022 축산기술과 산업 Vol.9 No.2
The objective of the present work was to evaluate the malodor-reducing effects of spraying fulvic acid in swine barns and providing to growing pigs in drinking water. Fulvic acids for drinking and for spraying to barns were prepared at 0.02%, and fulvic acid for spraying to compost were prepared at 0.1%. Prepared fulvic acid of 1 L was sprayed to the test nursery pig barns twice a week but was not sprayed to the control barn. Fulvic acid at 0.02% for drinking was provided to growing pigs for 4 weeks but was not provided to the control group. In the experiment for spraying to compost, 3 additives consisted of 1) probiotics 0.08 L, 2) probiotics 0.04 L + fulvic acid 0.04 L, and 3) fulvic acid 0.08 L were tested by adding to the compost samples of 80 L in 100 L plastic bucket for each and directly adding to the mechanical agitated composting facility. As a result of spraying fulvic acids to nursery pig barns, ammonia concentration was not increased compared with the control barn in which ammonia increased continuously. Fulvic acid provided to growing pigs did not result in difference of excreted ammonia compared with the control group. Probiotics, probiotics + fulvic acid, and fulvic acid sprayed to the test compost resulted in reduced malodor and ammonia after agitation compared with before agitation (p < 0.001) with the greatest effects in the fulvic acid group among the 3 additives. Additionally, the temperature of compost receiving fulvic acid reached 40℃ earlier than that of the control compost, which means that the time for primary fermentation of the compost was advanced by receiving fulvic acid. In conclusion, fulvic acid at 0.02% sprayed to pig barns and fed to pigs as water showed effective reduction of malodor, and fulvic acid at 0.1% sprayed to the compost reduced the time for primary fermentation and thus decreased the malodor.
Maternal Separation Does Not Produce a Significant Behavioral Change in Mice
Shawn Tan,Hin San Ho,송윤수,Joey Low,제현수 한국뇌신경과학회 2017 Experimental Neurobiology Vol.26 No.6
Early life adversities together with genetic predispositions have been associated with elevated risks of neuropsychiatric disorders during later life. In order to investigate the underlying mechanisms, many chronic, early-life stress paradigms in multiple animal models have been developed. Previously, studies reported that maternal separation (MS) in the early postnatal stages triggers depression- and/or anxiety-like behaviors in rats. However, similar studies using mice have reported inconsistent behavioral outcomes. In this study, we sought to assess behavioral outcomes from two different early-life stress paradigms; a conventional 3-hour MS and a maternal separation with early weaning (MSEW) paradigm using C57BL/6J male mice with independent cohorts. Our data demonstrated that both MS and MSEW paradigms did not produce reported behavioral anomalies. Therefore, MS paradigms in mice require further validation and modification.