산란계 평사 사육시 산란말기 L-tryptophan 급여 수준이 생산성, 깃털손상도 및 스트레스 수준에 미치는 영향

손지선,김희진,홍의철,김현수,유아선,전진주,윤연서,강환구,강보석 한국가금학회 2021 한국가금학회 정기총회 및 학술발표회 Vol.2021 No.11

Effect of single-sex or mixed rearing on growth and laying performance, blood parameters, egg quality, and feather scores of laying hens in an aviary system

손지선,김희진,홍의철,김현수,전진주,강보석,강환구 충남대학교 농업과학연구소 2022 Korean Journal of Agricultural Science Vol.49 No.1

The present experiment was conducted to evaluate the effects of single-sex or mixed rearing on the growth and laying performance, blood parameters, egg quality, and feather scores of laying hens in an aviary system. A total of 2,928 (females, 2,856; males, 72), Hy-Line Brown chickens at 20 weeks were evenly assigned to two treatments: termed here the single-sex (only female) and mixed-sex (female to male 20 : 1) conditions. They were allowed an ad libitum diet for 20 weeks in an aviary system. There were eight replicates of each treatment, each consisting of 12.42 m2·birds-1 (n=183), respectively. The body weight and uniformity in the mixed-sex condition were higher than those in the single-sex condition, but egg production did not show any significant differences between the two types of treatment for 20 weeks. The mixed-sex group showed an effect through stress parameters (corticosterone), whereas the feather score on the back was low at the end of the experiment. These results suggest that the presence of males affect corticosterone level for mating but can reduce the vigilance and aggressive behavior of laying hens.

A comparison between ketorolac and nefopam as adjuvant analgesics for postoperative patient-controlled analgesia: a randomized, double-blind, prospective study

손지선,고성훈,두아람,권영준,한영진 대한마취통증의학회 2017 Korean Journal of Anesthesiology Vol.70 No.6

Background: We compared the analgesic efficacy and side effects of ketorolac and nefopam that were co-administered with fentanyl via intravenous patient-controlled analgesia. Methods: One hundred and sixty patients scheduled for laparoscopic cholecystectomy were randomly assigned to ketorolac (Group K) or nefopam (Group N) groups. The anesthetic regimen was standardized for all patients. The analgesic solution contained fentanyl 600 μg and ketorolac 180 mg in Group K, and fentanyl 600 μg and nefopam 120 mg in Group N. The total volume of analgesic solution was 120 ml. Postoperative analgesic consumption, recovery of pulmonary function, and pain intensities at rest and during the forced expiration were evaluated at postoperative 2, 6, 24, and 48 h. The postoperative side effects of analgesics were recorded. Results: Cumulative postoperative analgesic consumptions at postoperative 48 h were comparable (Group K: 93.4 ± 24.0 ml vs. Group N: 92.9 ± 26.1 ml, P = 0.906) between the groups. Pain scores at rest and during deep breathing were similar at the time of each examination. The recovery of pulmonary function showed no significant differences between the groups. Overall, postoperative nausea and vomiting incidence was higher in Group N compared with Group K (59% vs. 34%, P = 0.015). The other side effects were comparable between both groups. Conclusions: Analgesic efficacies of ketorolac and nefopam that were co-administered with fentanyl for postoperative pain management as adjuvant analgesics were similar. However, postoperative nausea and vomiting incidence was higher in the nefopam-fentanyl combination compared with the ketorolac-fentanyl combination.

Sigma-1 Receptor Antagonist BD1047 Reduces Allodynia and Spinal ERK Phosphorylation Following Chronic Compression of Dorsal Root Ganglion in Rats

손지선,권영배 대한약리학회 2010 The Korean Journal of Physiology & Pharmacology Vol.14 No.6

Many therapeutic roles have been proposed for sigma-1 receptor (Sig-1R), but the involvement of Sig-1R in neuropathic pain has currently not been well explored. The present study aimed to evaluate the anti-nociceptive effect of Sig-1R antagonist (BD1047) in a rat model of chronic compression of the dorsal root ganglion (CCD), which is a model of human foraminal stenosis and radicular pain. When stainless steel rods were inserted into the intervertebral foramen of lumbar vertebrae 4 and 5, the CCD developed reliable mechanical (from 3 day) and cold allodynia (from 1 day) as compared with the sham operation group. The spinal expressions of Sig-1R and phosphorylation of extracellular signal-regulated kinase (pERK) were significantly increased from day 3 to day 14 after CCD surgery, as is consistent with the manifestation of allodynia. The BD 1047 (10, 30, 100 mg/kg) administered on postoperative days 0∼5 dose-dependently suppressed both the induction of allodynia and the elevation of the spinal pERK expression in a manner comparable with that of gabapentin (100 mg/kg). At 7 days post-CCD surgery, BD1047 (10, 30, 100 mg/kg) administration also produced anti-nociceptive effects on the mechanical and cold allodynia similar with those of gabapentin (100 mg/kg). Therefore, this data suggested that Sig-1R may play an important role in both the development and maintenance of CCD-induced neuropathy.

Pulmonary Edema following Phenylephrine Intranasal Spray Administration during the Induction of General Anesthesia in a Child

손지선,이상귀 연세대학교의과대학 2005 Yonsei medical journal Vol.46 No.2

Topical phenylephrine, an agent used to facilitate nasotracheal intubation and prevent nasal mucosal bleeding, can cause severe hypertension in some patients, secondary to its stimulation of alpha-adrenergic receptors. Moreover, a high incidence of pulmonary edema is found in patients whose phenylephrine administration is followed by treatment with beta-blocking agents. We report a case of acute pulmonary edema in a pediatric patient who developed severe hypertension after the inadvertent administration of a large dose of topical nasal phenylephrine, followed by beta-adrenergic antagonists (esmolol).

혹서피해 예방을 위한 방안 - 혹서기 농가 점검사항과 가금연구 추진 방향

손지선,Son, Ji-Seon 대한양계협회 2020 월간 양계 Vol.52 No.6

국립축산과학원 양계 연구 동향 - 스트레스 받으면 더 필요한 비타민

손지선,Son, Ji-Seon 대한양계협회 2022 월간 양계 Vol.54 No.2

원인에 있어서 자유로운 행위에 관한 연구

손지선 이화여자대학교 법학연구소 2008 法學論集 Vol.12 No.2

양계업 현안 및 발전방안 - 고온기 닭 영양관리

손지선 대한양계협회 2023 월간 양계 Vol.55 No.8

임신중단 규제에 대한 국민적 합의의 필요 - 도구성 극복과 휴머니즘 회복 -

손지선 한국형사정책학회 2019 刑事政策 Vol.31 No.3

This thesis worries that the request of the Constitutional Court of 2019.4.11 to the legislature about the improved legislation to penalize a pregnant for terminating the pregnancy after 22-week gestation period may restrict again the right of self determination of female which is acknowledged barely. Therefore this thesis aims to demonstrate that the punishment by the Criminal Law should not be allowed, that the regulation of the abortion by ‘the Criminal Law-the Mother and Child Health Law’ combination format should be abolished and the regulation should be delegated to the nation through the procedure of the substantial national consensus. This thesis tries to establish the correlation of the criminal abortion instrumentalised by the nation with the necessity of the abolition of the law, by applying the Max Horkheimer's critic of the instrumental reason which seeks to objectify and progress the instrumentation of the reason through its self-criticizm. In order to do supra, this thesis endeavors to expiscate the things ① which the thought process of ‘females are humanbeings’ is removed in the process of acknowledging ‘the right of the fetal life’ as the basis of the existence of the criminal abortion by the court, ② which females are excluded from ‘the right of the human dignity and value’ and ‘the right to pursue happiness’ in the Constitution because of ①, ③ which the two-way race of ‘the right of fetal life vs. the right of self determination of female’ is the output that is missing out ‘the maternal instinct recongnition sensitivity’, and ④ which the content about the deliberation and determination of a pregnant woman for the fatal life and living after the birth is included among the right of self determination of female by proposing ‘the right of fetal profit determination of the pregnant woman’. At last, this thesis attempts to illuminate the things, even if the criminal abortion has to be abolished for the above mentioned reasons, ① which the female-centerd reason has to take care not to disvalue the fetal life through self-criticism, as Horkheimer demands the constant self-criticism of the reason in his denial philosophy, and ② which this thesis counts on the gender community progressing dialectically through interaction toward the gender equality. 본고는, 최근 헌법재판소가 자기낙태죄의 헌법불합치 결정을 내리면서 입법자에 대해 헌법이 용인할만한 낙태처벌을 내용으로 하는 개선입법을 요구한 것이, 자칫 또 다른 형태의 처벌조항이 신설됨으로써 헌법상 기본권으로서 가까스로 인정받은 임부의 자기결정권에 다시 제한을 가하는 결과를 초래할 것을 우려한다. 그러므로 본고는 국가형법에 의한 임신중단의 처벌은 인정되어서는 안 된다는 점, 형법과 모자보건법 결합방식에 의한 낙태규제는 폐지되어야 한다는 점, 그리고 임신중단의 규제는 실체가 있는 국민적 합의절차를 통해 국가에 위임되어야 그 정당성이 인정된다는 점을 논증하는 것을 목표로 한다. 본고는, 이론적으로, 국가에 의해 도구화된 낙태죄와 그 폐지의 필요성의 상관관계를 ‘이성의 도구화를 이성의 자기비판을 통해 객관화하여 그 발전을 모색’하는 내용의 호르크하이머의 ‘도구적 이성 비판론’을 적용하여 규명하고자 한다. 그리고 본고는 법원의 판결문이 낙태죄 존립근거로 태아생명권을 인정하는 과정에 여성이 인간이라는 사고과정이 제거되었다는 점, 그로 인해 헌법이 인정하는 인간의 존엄과 가치 및 행복추구의 기본권이 여성에게 배제되어왔다는 점, 그리고 태아이익과 여성의 자기결정권 대결구도가 여성의 ‘모성인지감수성’을 결여한 결과물이라는 점을 밝히고, 임부결정권에 태아의 이익에 관한 사항이 포함된다는 의미를 가지는 ‘이익포함론’을 제안하여 임부의 자기결정권은 임신기간 전체에 걸쳐 보장되어야 한다는 점을 규명하고자 한다. 그리고 본고는 호르크하이머가 부정의 철학에서 이성의 끊임없는 자기비판을 요구한 것처럼, 여성중심의 주관적 이성은 자기비판을 통해 태아생명경시(야만의 역사)를 경계(야만의 극복)해야 한다는 점과 국민적 합의절차를 통해 국가에 위임된 내용의 개선입법은 이러한 내용들을 포함해야 한다는 점(휴머니즘의 회복)을 주장하고자 한다.