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사회취약계층 가정의 실내 유해 인자 농도와 아토피피부염
서성철 ( Sung Chul Seo ),강인순 ( In Soon Kang ),임수길 ( Soo Gil Lim ),정지태 ( Ji Tae Choung ),유영 ( Young Yoo ) 대한천식알레르기학회 2015 Allergy Asthma & Respiratory Disease Vol.3 No.3
Purpose: The aims of this study were to examine indoor concentrations of air pollutants in socioeconomically disadvantaged houses and to investigate relationships between indoor air pollutant levels and the severity of atopic dermatitis (AD). Methods: A total of 54 children who had a past history or current symptoms of AD were enrolled in the study. To evaluate the levels of indoor air pollutants, we measured concentrations of CO2, total volatile organic compounds (TVOC), formaldehyde, particulate matter with diameter less than 10 μm (PM10), airborne mold and numbers of house dust mite (HDM) in dust of the children’s houses. All studied subjects completed physical examination for the severity of AD and blood tests. Results: Although the mean (±standard deviation [SD]) concentration of indoor CO2 (600.6±179.4 ppm) was lower than the standard recommended levels of multiplex buildings in Korea, there was a significant correlation between CO2 concentrations and the severity of AD (r=0.302, P=0.030). The geometric means (range of 1 SD) of TVOC (42.5 μg/m3 [22.2.81.5]), formaldehyde (24.3 μg/m3 [15.0.39.9]), PM10 (26.6 μg/m3 [14.6.48.4]), and airborne mold (49.9 CFU [colony forming unit]/m3 [26.3.94.6]) were not significantly higher than the standard recommended levels of multiplex buildings. Two-thirds of the subjects were sensitized to at least 1 of the common allergens. Conclusion: Generally, indoor air pollution was not serious in socioeconomically disadvantaged households. However, indoor CO2 concentrations are closely related to the severity of AD in children living in socioeconomically disadvantaged houses. Environmental amelioration targeting vulnerable population may improve the quality of life and decrease the prevalence of environmental allergic diseases.(Allergy Asthma Respir Dis 2015;3:206-212)
자하거약침자극(紫河車藥鍼刺戟)이 HgCI<sub>2</sub>로 손상(損傷)된 흰쥐의 신장(腎臟) 및 간장(肝臟)에 미치는 영향(影響)
이상길,서성철,최도영,박동석,이윤호,강성길,Lee, Sang-Keel,Seo, Jung-Chul,Choi, Do-Yong,Park, Dong-Suk,Lee, Yun-Hoo,Kang, Sung-Keel 대한약침학회 2000 Journal of pharmacopuncture Vol.3 No.2
Objective: This study was perfomled to examine the therapeutic effect of aqua-acupuncture solution of Hominis Placenta(HP) on kidney and liver intoxicated by $HgCI_2$ in rats. Methods: $10\%$ and $25\%$ HP aqua-acupuncture were carried out everyday for 8 days on corresponding bilateral loci of Shinsu(BL23) and Kansu(BL18), respectively, after mercuric chloride intoxication in rats. Thereafter BUN, creatinine, GOT, GPT, ALP, ${\gamma}$-GT, albumin and total bilirubin were measured before intoxication, and at the 4th and the 8th experimental day. Histopathological and immunochemical observation were also carried out. Results: 1. It showed significant decreases of BUN in the group of $10\%$ HP aqua-acupuncture into Shinsu on the 4th experimental day as compared with the control group. 2. It showed significant decreases of creatinine in the group of $10\%$ HP aqua-acupuncture into Shinsu on the 4th and the 8th experimental days as compared with the control group. 3. There were not any significant changes of GOT, GPT, ALP,${\gamma}$-GT, albumin and total bilirubin in the HP aqua-acupuncture groups compared with the control group. 4. By the histopathological observations on kidney under a light microscope, alt the $10\%$ and $25\%$ HP aqua-acupuncture into Shinsu showed the preventive effect on tubulo-interstitial necrosis and muItifocal calcification in tubular lumen respectively compared with the control group. 5. By the histopathological observations on liver under a light mIcroscope, the groups $10\%$ and $25\%$ HP aqua--acupuncture into Kansu did not show any significant changes in the liver compared with the control group. 6. By the immunochemical analysis of heat shock protein(hsp) and glucose-regulated protein(grp) in rat renal cortex, the expressions of hsp70 and grp78 were decreased in the $10\%$ and $25\%$ HP aqua-acupuncture into Shinsu respectively compared with the control group. Conclusion: These results suggest that Hominis Placenta aqua-acupuncture have an effect on prevention and protection of renal intoxication by $HgCI_2$ in rats.
해외건설공사 EPC/Turnkey 계약조건 핵심 리스크 세부조항 도출 - FIDIC Silver Book 2017년 개정판 기준으로 -
홍성열,제재용,서성철,박형근,Hong, Seong Yeoll,Jei, Jae Yong,Seo, Sung Chul,Park, Hyung Keun 한국건설관리학회 2022 한국건설관리학회 논문집 Vol.23 No.6
Recently, the global construction market is expected to grow at an annual average of 4.8% by 2025 and the risk of overseas construction is also expected to increase accordingly. In particular, domestic construction companies intensively participated in the EPC(Engineering, Procurement, Construction)/Turnkey project, but as a result of failing to respond to contractual risks, they have suffered losses of trillions of won in overseas business since 2013. Nevertheless, there have been not many studies on the derivation of EPC/Turnkey's contractual key risk sub-clauses. Therefore, in this study, the key risk sub-clauses were studied for the conditions of the 2017 Silver Book contract issued by the International Consulting Engineering Federation(FIDIC). To this end, 30 experts with more than 10 years of experience in international construction contracts were formed as a panel to conduct a Delphi survey on 170 sub-clauses of 21 clauses of FIDIC Silver Book to derive 62 main risk sub-clauses. In addition, the RPN(Risk Priority Number) was finally calculated using the FMEA(Failure Mode and Effect Analysis) technique, and 25 key risk sub-clauses within the Critical Risk range were derived. Through the results of this study, the practical point of view is able to refer to the contract provisions to be carefully reviewed at the bidding and contract signing stage in overseas construction projects. From an academic point of view, it provides direction and basic knowledge of how to study the contract fields used in overseas construction EPC/Turnkey projects.
국내·외 라돈 관련 제도 비교를 통한 산업안전보건법 개선방안
임대성 ( Dae Sung Lim ),김기연 ( Ki-youn Kim ),조용민 ( Yong Min Cho ),서성철 ( Sung Chul Seo ) 한국산업보건학회 2021 한국산업보건학회지 Vol.31 No.3
Objectives: Concerns have been raised about the possible health effects of radon on both workers and consumers with the spread of social attention to the impact of radon exposure. Thus, an entire raw material handling workshop was investigated, and standards for radon levels in the workplace were newly established at 600 ㏃/㎥. However, regulations on the management of workers exposed to radon are still insufficiently developed. Therefore, by comparative analysis of overseas and domestic radon-related regulations for workplaces, this study aims to suggest improvement plans of protection regulations under the Occupational Safety and Health Act (OSH Act) for the prevention of health disorders of radon-exposed workers. Methods: For overseas case studies, we consulted radon-related laws and reports officially published on the websites of the European Union (EU), the United States (U.S.) and the United Kingdom (UK) government agencies. Domestic law studies were conducted mainly on the Act on Protective Action Guidelines against Radiation in the Natural Environment and the OSH Act. Results: In Europe, the basic safety standards for protection against risks arising from radon (Council Directive 2013/59/EURATOM of 5 December 2013) was established by the EU. They recommend that the Member States manage radon level in workplaces based on this criterion. In the U.S., the standards for workplaces are controlled by the Occupational Safety and Health Administration (OSHA) and the Mine Safety and Health Administration (MSHA). Action on radon in the UK is specified in “Radon in the workplace” published by the Health and Safety Executive (HSE). Conclusions: The Act on Protective Action Guidelines against Radiation in the Natural Environment mainly refers to the management of workplaces that use or handle raw materials but does not have any provisions in terms of protecting naturally exposed workers. In the OSH Act, it is necessary to define whether radon is included in radiation for that reason that its current regulations have limitations in ensuring the safety workers who may be exposed to naturally occurring radon. The management standards are needed for workplaces that do not directly deal with radon but are likely to be exposed to radon. We propose that this could be specified in the regulations for the prevention of health damage caused by radiation, not in Article 125 of the OSH Act.
직장 임산부의 운동참여가 우울 및 분만자신감에 미치는 영향
전선혜(Sun Hye Jun),서성철(Sung Chul Seo) 한국사회체육학회 2010 한국사회체육학회지 Vol.0 No.41
The purpose of this study was to find the effects of exercise of working pregnancy on depression and delivery self efficacy. Data was collected by self-report from 380 pregnant, the questionnaire contents were exercise experience, depression, and delivery self-efficacy. The data analysed factor analysis, frequency analysis, one-way ANOVA, Scheffe test, pearson correlation, and multiple regression by SPSS WIN 15.0. All the statistical significance level set is to p<.05 from the analysis data, this study reaches the following conclusions: First, exercise participation was found to have a positive effect on psychological depression. Second, exercise participation and working pregnancy were found to have a positive effect on psychological, physical, and physiological delivery self efficacy. The current study suggests it is necessary that every company and working place offer exercise circumstance for pregnant and baby`s health.
천식 소아에서 호기산화질소 농도와 기도 과민성, 혈액 호산구 수, 혈청 호산구 양이온 단백 농도와의 상관관계
서현석 ( Hyeon Seok Seo ),정보현 ( Bo Hyun Chung ),박하늘 ( Ha Neul Park ),서성철 ( Sung Chul Seo ),( Bauer Siegfried ),송대진 ( Dae Jin Song ),정지태 ( Ji Tae Choung ),유영 ( Young Yoo ) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 2012 소아알레르기 및 호흡기학회지 Vol.22 No.3
Purpose: The measurement of fraction of nitric oxide (FeNO) is a noticeable tool that reflects airway inflammation in asthmatic patients. We wanted to find out the relationship between pulmonary function, bronchial hyperresponsiveness (AHR), blood eosinophilic inflammatory markers and FeNO level before and after methacholine bronchoprovocation test in asthmatic patients. Methods: Fifty-five children, who visited the Allergy Clinic of Korea University Anam Hospital from March 2011 to February 2012, due to asthmatic symptoms, such as history of episodic wheezing or dyspnea during the previous year and resolved after using bronchodilators, were enrolled. We performed the baseline pulmonary function and methacholine bronchoprovocation test in the enrolled patients. Blood eosinophil counts and blood eosinophil cationic protein (ECP) were measured. FeNO levels were measured before and after the methacholine bronchoprovocation test. Results: The mean FeNO levels (36.3 ppb) fell after methacholine bronchoprovocation test (25.7 ppb). Forced expiratory volume in one second (FEV1) %pred inversely correlated both with FeNO level before (R2=0.07, P =0.029) and after (R2=0.059, P =0.01) methacholine bronchoprovocation test. The provocative concentration, causing a 20% decrease in FEV1 to methacholine (methacholine PC20) inversely correlated both with FeNO levels before (R2=0.086, P =0.001) and after (R2=0.141, P =0.001) the challenge. FeNO level measured at bronchoconstriction state significantly correlated with blood eosinophil counts (R2=0.112, P =0.028). Serum ECP levels correlated FeNO level, neither before nor after bronchoprovocation. Conclusion: The baseline FeNO levels were higher in asthmatic children. However, FeNO levels rather decreased after methacholine induced bronchoconstriction. Repeated spirometry maneuver was considered to have an effect on reducing FeNO levels. FeNO correlated with pulmonary function, airway AHR and blood eosinophil counts.