농촌 주민들의 심전도 소견에 관하여

서석권,윤능기,이성관 대한보건협회 1985 대한보건연구 Vol.11 No.2

SJAS로 측정한 A 형행동양상과 사회인구학적인 변수

서석권 啓明大學校 醫科大學 1988 계명의대학술지 Vol.7 No.2

To investigate the sociodemographic variables to enhance and maintain the Type A behavior Pattern (TABP) socially by comparing the differences of sociodemographic variables of the A-B Behavior Pattern measured by the Student Jekins Sctivity Survey(SJAS, short form), the authors conducted a questionnaire survey using a medical school undergraduated(413) as a study population April to May, 1988. The cut-off point which divides into A-B Behavior Pattern was ±1 standard deviation of the total score of the SJAS(≤3, ≥10), resulting in 61 TABP & 82 Type B Behavior Pattern (TBBP). The reliability coefficient of the total score of the SJAS measured by Cronbach's alpha was 0.72. In the family environments, there were no difference in the place raised, deceased father, age of father between TABP and TBBP. The Hollingshead's socioeconomic status index which was dichotomized by median value showed a statistically significant difference; The high index group was 47.4% in TABP and 65.8% in TBBP(P=0.03). TABP showed little difference in age, sex, and proportion of those who have a religion compared with the TBBP. The proportion of those who suffered a failure more than once academically after entering the medical school was 19.7% in TABP and 35.4 in TBBP which was statistically significant(P=0.04). TABP was not different from TBBP in the habits of smoking and alcohol consumptions. The smaller proportion of failure suffered in TABP than TBBP could explain the competitive and hard-driving aspects of the TABP and the socioeconomic status may exert a different influence on the socialization pressure leading to the formation of the TABP in the early life from the American's.

농업종사자(農業從事者)의 혈장(血漿) Cholinesterase 치(値) 변화(變化)에 관(關)한 연구(硏究)

서석권,황인담,Suh, Suk-Kweon,Hwang, In-Dam 한국농촌의학지역보건학회 1983 농촌의학·지역보건 Vol.8 No.1

살충제(殺蟲劑)의 주종(主宗)을 이루는 유기인제(有機憐劑)에 의한 만성중독(慢性中毒)의 예방(豫防)을 위(爲)한 기초자료(基礎資料)를 얻고, 또한 농업종사자(農業從事者)의 혈장(血漿) cholinesterase의 정상치(正常植)를 추정(推定)하고저 전라북도(全羅北道) 정읍군(井邑郡)의 일부(一部) 농업종사자(農業從事者)에 대(對)한 혈장(血漿) cholinesterase 치(植)를 Takahashi의 Micro- method로 측정분석(測定分析)한바 다음과 같이 요약(要約)된다. 1) 농약살포전군(農藥澈布前群)의 혈장(血漿) cholinesterase 치(植)는 $7.60{\pm}1.74{\mu}M/20{\mu}{\ell}$/hr.였고, 살포후군(撒布後群)에서는 $6.23{\pm}1.59{\mu}/20{\mu}{\ell}$/hr.로서 살포전군(澈布前群)보다 $1.37{\mu}M/20{\mu}{\ell}$/hr.가 낮게 나타났다 (P < 0.01). 2) 농업종사자(農業從事者)의 정상(正常) 혈장(血漿) cholinesterase 치(植)의 95% 신뢰구간(信賴區間)은 $7.30-7.90{\mu}M/20{\mu}{\ell}$/hr.이었다. This study was carried out to obtain the basic data for the prevention of chronic poisoning by organic phosphorous pesticides and to estimate the normal range of plasma cholinesterase activity level for Korean agricultural workers. The 285 agricultural workers were randomly selected for the study in Jungup Gun, Jeonbug Province, 135 persons of them were tested in the period of pre-exposure of organophosphorous pesticides (April 1981) and rest of them were tested after exposure(August 1981). Cholinesterase activity levels were measured by the Micro-method of Takahashi Hiroshi. Major findings are as following: 1) There is significant difference in plasma cholinesterase activity levels between the pro-exposed and post exposed group(p > 0.01). Mean values of plasma cholinesterase activity levels were $7.60{\pm}1.74{\mu}M/20{\mu}{\ell}$/hr. in the pre-exposed group and $6.23{\pm}1.59{\mu}M/20{\mu}{\ell}$/hr. in the post-exposed group. 2) Plasma cholinesterase activity in Korean agricultural worker could be estimated $7.30-7.90{\mu}M/20{\mu}{\ell}$/hr. with 95% confidence interval.

톨루엔 취급자들의 면역기능에 관한 조사

서석권,이종영,이승훈,Suh, Suk-Kwon,Lee, Jong-Young,Lee, Seoung-Hoon 대한예방의학회 1992 예방의학회지 Vol.25 No.2

톨루엔의 폭로가 인체의 면역기능에 미치는 영향에 대해 알아 보기 위하여 톨루엔 취급자 21명과 일반 사무직 근로자 12명에 대하여 혈액 및 말초혈액 림프구의 subpopulation에 대하여 조사하였다. 혈액소견은 두 군 모두 정상범위로 통계적으로 유의한 차이가 없었다. CD4 림프구 세포의 비율은 두 군에서 유사하였으며 T와 B림프구 및 CD8 림프구 세포의 비율은 폭로군에서 약간 낮았으나, 두 군 모두 정상 범위로 통계적으로 유의한 차이가 없었다. 폭로군에서 T 림프구 및 CD4 세포의 비율은 근무기간이 길수록 통계적으로 유의하게 증가하였다(P<0.05). 본 연구의 폭로군에서 림프구의 subpopulation은 전반적으로 비폭로군보다 약간 낮은 경향은 있었지만, 정상범위에 해당하였으므로 톨루엔에 폭로되었을 때 인체에 대한 면역기능은 큰 영향이 없는 것으로 생각되어진다. 그러나 폭로기간에 따라 면역기능이 변동하는 것으로 보아 톨루엔이 인체의 면역기능에 미치는 영향에 관한 지속적인 연구가 이루어져야 하겠다. To assess the immunological function of toluene exposed group, the proportions of T lymphocyte, B lymphocyte, CD4 cell, CD8 cell, the ratio of CD4 to CD8(CD4/CD8) in peripheral blood were measured on twenty-one toluene exposed workers and twelve healthy workers who did not have previous history of toluene exposure. In addition, to evaluate the present status of toluene exposure, urinary hippuric acid concenturations were measured in exposed group. The mean concenturation of urinary hippuric acid was 2.84 g/creatinine g in exposed group. The proportions of T lymphocyte, B lymphocyte, CD8 cell and CD4/CD8 of exposed group were slightly lower than non-exposed group except the proportion of CD4 cell which was similar in both groups. But these differences were not statistically different in both groups. The proportions of T lymphocyte and CD4 cell were significantly correlated with the length of duration in exposed group(P<0.05).

농촌주민들의 心電圖所見에 관하여

이성관,서석권 啓明大學校 醫科大學 1985 계명의대학술지 Vol.4 No.2

농촌주민 20세이상 남녀 각각 200여명을 임의추출하여 심전도소견과 이와 동시에 조사한 혈청콜레스테롤치, 혈당치, 혈압, 음주 및 흡연과의 관계를 관찰한 바 다음과 같은 성적을 얻었다. 1. 심전도상 이상소견자는 전체로 45%로서 남자 52.7%, 여자가 37.3%였다. 이중 경한 좌심실비대, 저전위, QT간격연장 등 경한 이상이 16.1%로서 남자가 21%, 여자가 11.3%였다. 중등도의 좌심실비대, ST, T.U파의 변화등 중등이상자는 전체 24.1%로 남자가 26.8%, 여자가 22.1%였다. 완전우지 block, 초단계 심방심실 block, 심근경색중등 심한 변화는 4.4%로 남자가 4.9%, 여자가 3.9%였다. 2. 심전도소견 변화는 년령이 증가함에 따라 증가했으며 특히 40세이상에서 갑자기 증가하였다. 3. 심전도소견과 다른 인자와의 관계에서 콜레스테롤치가 높은 사람, 혈당치가 높은 사람, 수축기, 이완기혈압이 높은 사람 및 음주자에게 콜레스테롤 및 혈당치 그리고 혈압이 낮은 사람이나 비음주자보다 이상소견이 고율이었다. 흡연유무별로는 흡연자에서 이상소견이 약간 높은 경향이 있었다. The study was conducted to investigate the ECG findings on 409 subjects who were over 20 years old age in Kyung San Gun, Kyung Pook Province. We observed ECG findings and the effects of serum cholesterol, blood sugar, proteinuria, drinking and smoking on ECG findings. The results were as flollows: 1. The rate of frequency of abnormal ECG findings in the subjects was 45.0%, (male 52.7%, female 37.3% respectively). 2. According to severity of abnormal ECG findings, the rates of slight(not definite). moderate (suggestive), and severe(definite) findings were 16.1%, 24.1% and 4.4% respectively. 3. The rate of abnormal ECG findings was increased with age advancing. 4. Regarding to the contents of abnormal ECG findings, there were left ventricle hypertrophy 27.6%, St, T, and U were changes 4.2%, QT prolongation 4.0% and low voltage 2.8% respec-tively. 5. The rate of abnormal ECG findings in those who were in high cholesterol and high blood sugar were higher than that of those who were in low cholesterol and low blood sugar. The rate of abnormality of those who were hypertention was significantly higher than that of those who were normal blood pressure.

종합검진센터 내원자에서 관상동맥질환 위험요인들의 분포

이충원,이종영,박종원,윤능기,김영조,이현우,이무식,서석권 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3

1991년3월부터 8월사이에 대구시에 소재한 1개의 대학병원의 종합검진센타에 내원해서 종합검진을 받은 남자 422명(69.9%)과 여자 182명(30.1%)을 대상으로 하여 심헐관계질환의 위험요인들의 전체적인 분포를 보았다. 평균 연령은 남자가 43.3(표준편차, 10.3), 여자가 44.4(표준편차, 10.8)였다. 남자에서 연령에 따라 0.05 수준에서 통계적인 유의성을 보인 위험인자는 혈청 총콜레스테롤(TC). 트리글리세라이드(TC), 고밀도 지단백콜레스테롤(HDL), 저밀도 지단백콜레스테롤(LDL), 수축기혈압, 비체중, A형행동양상이었으며 생활습관으로서는 음주, 흡연, 규칙적인 운동, 우유와 커피섭취, 수면 등이었다. 여자에서는 TC, TG, LDL, 수축기와 확장기혈압, 비체중 그리고 커피섭취와 수면 등이었다. 남자에서 총콜레스테롤의 평균은 181.7mg/dl(표준편차, 32.2), 여자는 182.5mg/이(표준편차, 42.2)였다. 대부분의 위험인자들은 구미의 수준에 미치지 못했으나 남자에서 흡연율이 전체적으로 61.8%로 높으 수준이었으며 특히, 20~29세가 72.9%, 30~39세가 75.2%로서 다른 연령군에 비해 상대적으로 높았다. 여자에서는 전체적으로 6.0%에 지나지 않았다. 확장기혈압 90mmHg 이상을 고혈압자로 정의했을 때의 유병률이 여자 전체대상자에서 24.7%로 높았으며 50-59세는 표본수가 적어서 문제가 되었으나 53.1%였다. 어떤 인구집단내에서 총콜레스테롤의 평균이 200mg/dl 미만이면 고혈압과 흡연의 인구집단의 수준에 관계없이 관상동맥질환(coronary heart disease)의 발생은 드문 것으로 보고가 되고 있으므로 당분간 관상동맥질환 발생률의 급속한 절대적인 증가는 힘드리라 사료된다. 그러나 이러한 결과는 본 연구의 대상자들이 대표성을 지니지 못하며 건강검진센터에 자발적으로 내원한 사람들이므로 해석에 주의를 요한다. Authors examined the distributions of the risk factors for the coronary heart disease in the 422 male (69.9%) and 182 female (30.1%) visitors to the health examination center of a university hospital located in Taegu March to August 1991. Mean age of males was 43.3(standard deviation, SD 10.3) and that of females was 44.4(SD 10.8). Total cholesterol(TC), triglyceride (TG), high-density lipoprotein and low-density lipoprotein cholesterol(LDL), systolic blood pressure, Quetelet index, and Type A Behavior Pattern, and some of life habit variables(alcohol intake, smoking, regular exercise, milk and coffee intake and sleeping) were statistically significant in age groups of the males(P<0.05). In the females, TC, TG and LDL, systolic and diastolic pressure, Quetelet index, coffee intake and sleeping were statistically significant in age groups (P<0.05). Mean of total cholesterol was 181.7㎎/dl(SD,32.2) in males and that of females was 182.5㎎/dl(SD,42.2). Most of the risk factors levels were lower than the Euro-Americans', while smokers were high with 61.8%, especially 72.9% in 20-29 age group and 75.2% in 30-39 age group in males. In females, smokers were just 6.0%. Hypertensives defined by more than 90mmHg diastolic pressure were 24.7% in females, particularly 53.1% in 50-59 age group, but size of the strata was rather small(N=49). In the light of the report that coronary heart disease is uncommon irrespective of population levels of smoking and hypertension, where average total blood cholesterol level in a population is low(<200mg/dl), it is not likely that the absolute increase of the number of the coronary heart disease will increase markedly in the near future. But cautions should be exercised in interpreting the results of this study due to the lack of representativeness and volunteerism. .

K 대학병원 서어비스에 대한 소비자 만족도

이태섭,박종원,이무식,윤능기,이충원,서석권 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3

Authors administered a questionnaire to 300 clients visited to the K University Hospital during August in 1992 to investigate the degree and related factors of consumer's satisfaction with the hospital services. Clients consisted of 82 in-patients and 158 out-patients, 52.4 percent of them was male. Four dimensions of satisfaction were assessed which were medical management, administration, environment and attitude. In-patients reported as dissatisfied with the waiting time during receipt, investigative medical procedures and pharmacy (64.7%), lack of conveniency facilities for patients and their guardians(48.8%) and provision of conveniency facilities in the ward(42.4%), unsanitary state of out- and in-hospital(41.5%). Out-patients reported dissatisfaction with the course of medical management and the time needed(70.3%), the waiting time during receipt, investigative medical procedures and pharmacy(68.3%), lack of conveniency facilities for patients and guardians(42.4%). But both in-patients and out-patients were satisfied with medical equipments, doctor's diagnosis reliability and medical effects, technician's attitude more than 50%. Canonical correlation analysis was done to find related sociodemographic factors to the four dimensions of satisfaction. Of the four canonical functions, the first was only statistically significant in in-patients. Its eigen value was 0.56 and its canonical correlation coefficient was 0.60. Satisfaction with environment and medical management was selected as important concept in dependent variables. Standardized canonical function of environment and medical management were 0.76 and 0.35 respectively. It was related with woman with high educational attainment and increasing number of hospital visits. In out-patients, the first, second and third function were statistically significant and their eigen values were 0.18, 0.4, 0.08 respectively which were small compared to those of in-patients. Their canonical correlation coefficient were 0.40, 0.35, 0.28 respectively. Low degree of environment but high degree of medical management satisfaction was noted in the first function which was related with old age, woman and professional occupation. Low degree of satisfaction with administration(second function) was related with city resident, non-professional occupation and young age. High degree of medical management but low degree of administration satisfaction(third function) was related with surgical visitor, man and non-professional occupation. The direction of hospital managerial strategies could be planned and general characteristics of dissatisfactory clients might be suggested with these results.

A형행동양상과 사회적인 지지 및 혈청 총콜레스테롤과의 상관성

서석권,구은수,이충원 啓明大學校 醫科大學 1991 계명의대학술지 Vol.10 No.1

The objective of the study was to determine whether there are relationships of type A behavior pattern(TABP) and social support to serum total cholesterol and interaction between TABP and social support. The sample(N=389) was accrued by the author's convenience from those who had visited the depatment of family medicine of the Dongsan Medical Center to take a periodic medical examination by a preventive program of medical insurance for the public officials and private school teachers and employees, from whom 24 excluded due to missing questionnaire items and drugs or conditions which can influence the serum total cholesterol abnormally. Male were 235(64.4%) and mean ages were 40.1(males) and 29.1(females). After inclusion of the control variables, body mass index(Quetelet index), age and subjective ratings of dietary fat intake in stepwise multiple linear regression models by gender, TABP measured by Framingham Type A Scale(FTA) was not related to serum total cholesterol in both sexes. Of the 3 scoial support indices measured by Hanson's avilability of material and informational support(MIS), adequacy of Framingham Type A Scale(FTA) was not related to serum total cholesterol in both sexes. Of the 3 social support indices measured by Hanson's availability of material and informational support(MIS), adequacy of emotional support and total score summed up 3 indices were selected in males(R2= 0.164, 0.161, 0.171, respectively, P<0.001), but none of the indices were selected in females. The only interaction term selected was between TABP and MIS whcih was help in females(R2=0.190, P<0.11).

대구시 모 보건소에 내소한 성병환자에 대한 연구

윤능기,서석권 啓明大學校 醫科大學 1988 계명의대학술지 Vol.7 No.2

The authors selected the medical records of the 2,346 diagnosed urethritis and syphilis patients from those who visited to a public health center in Taegue City, 1, January 1985 to 31, December 1987 to treat their urologic symptoms. Their medical records were used to investigate distribution status of the infection by demorgaphic and temporal variables. The results were as follows: 1. The most frequent age group was 20-29 years of age, 65.6%, and the less than 20 years of age group was 10.2%. In 30-39 age group, males 17.9% and females 23.0% and in 40-49 group, males 4.5% and females 12.2%. The female excess prevalence remained the same after that age group. 2. The order of relative frequency of the infection by month in which 3-year cases were combined was August, 11.3%, July 10.9%, January, 10.3% and the monthly distribution of the student was August, 16.0%, January, 11.6%, March, 10.7%, which suggests a coincidence with the periods of the school vacations. The seasonal distribution was summer 31.2%, spring 25.5%, autumn 21.7%, winter 21.5%. 3. The relative frequency of infection by martial status showed the unmarried was 70.3% and the married 29.37%, which was a significant difference. 4. The distribution by occupation was merchants 25.5%, office workers 19.2% and students 15.5% which was unexpectedly high. 5. In the distribution by source of infection of the males, friends was the most frequent source with 28.7%, restaurant employees 25.2%, prostitutes 16.8%, prostitutes 16.8%, and employees of lodging service 12.4%. 6. In the distribution by age and source of infection, friends were the most frequent source of infection(63.1%) in the less than 20 years of age group. In 20-29 years of age group, friends were 28.6%, restaurant employees 24.5%, prostitutes 17.8%, where showed increasing proportions of employees of the service trade. In 30-39 years of age group, restaurants employees 35.9%, employees of the lodging service 15.9%, prostitutes 14.9%, which means that most of sources of infection were employees of the service trade. In 4.-49 years of age group, restaurant employees 39.7%, prostitutes 17.2% and in 50-59 group, spouse was the most frequent(27.3%) and in the more than 60 years of age group prostitutes was 50%, but the total cases of that age group were too small to tabulate meaningfully. 7. The relative frequency of infection by infection history showed the inexperienced ws 48.4% and the experienced 51.6% and in the inexperienced, males 47.9% and females 78.1%.

Epidemiological survey of Paragonimus westermani among residents in Ulchin county, Kyungpook Province, Korea

徐錫權,朱鍾潤 啓明大學校 醫科大學 1990 계명의대학술지 Vol.9 No.2

肺吸蟲 浸潤地로 알려진 慶北 蔚珍郡 住民들에 있어서 肺흡蟲 最近 感染狀을 알아보기위해 1989年 3月부터 1990年 6月까지 蔚珍郡內 10個面 43個部落 住民 1.262名을 調査對象으로 皮內反應을 調査함과 同時에 調査地域에서 採集한 가재에서 本蟲 被襄幼蟲 感染狀을 調査하였다. 調査마을 43個 가운데 22個마을 住民들에 있어서 肺吸蟲 陽性者가 檢出되었으며, 그 率은 最高 29.8%, 最低 1.3%로 마을마다 큰 差異를 나타내었다. 住民 1.262名中 皮內反應 陽性者는 146名, 그 率은 10.2%였으며, 性別感染率에 있어서는 男性에서는 12.4%, 女性에서는 10.2%로 兩者間에 有意的 差를 認定할 수 없었다. 皮內反應 陽性者 146名 가운데 18名은 喀痰儉査에서 蟲卵을 檢出할 수 있었으며, 3名은 大便檢査에서만 蟲卵을 檢出할 수 있었고, 9名은 喀痰 및 大便檢査 모두에서 蟲卵을 發見할 수 있었다. 年令群別 感染率에 있어서는 0-9歲群에서는 6.4%였으며, 年令이 많이질수록 그 率도 增加하여 30-39歲群에서는 最高値 31.7%를 나타내었다. 調査地域에서 授集한 가재에서 肺吸蟲 被襄幼蟲 檢出率은 地域에 따라 큰 差異를 나타내었고, 가재 部位別 寄生狀은 頭胸部(69.1%), 아가미(25.2%), 및 肝(5.5%) 順이었으며, 가재 한마라當 肺吸蟲 皮襄幼蟲數는 1.8個였다. 調査地域 住民들에 있어서 肺吸蟲에 對한 保建知識 및 中間宿主 攝取에 關한 設問書 調査에서는 皮內反應 陽性者와 陰性者사이에 뚜렷한 差를 認定할 수 없었으며, 肺吸蟲 感染에 關한 知識을 얻을 수 있었던 保建敎育 媒體의 種類는 學校敎育을 통하여 알게 되는 경우가 41.5%로 가장 높았으며, 다음은 라디오 텔레비젼(25.5%), 保建所(13.4%) 및 病院(12.5) 順이었다. 以上의 成績으로 미루어보아 慶北 蔚珍郡은 肺吸蟲 流行地域으로 남아 있을뿐만 아니라 住民들에서의 肺吸蟲 感染率은 아직도 높음을 알았다.