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체중감량성공에 효과적인 체중감량요법 그리고 체중감량성공과 정신건강 간의 상호관계 분석: 국민건강영양조사 제7기 1차년도(2016년) 자료
배형우,김원용 대한가정의학회 2020 Korean Journal of Family Practice Vol.10 No.6
Background: This study was conducted to evaluate the effect of a weight loss method in individuals who successfully lost weight and determine themental health problems that might have occurred while losing weight. Methods: Data were obtained from the Seventh Korea National Health and Nutrition Examination Survey in 2016. First, an independent sample t-testwas used with continuous data to identify the relationship between successful weight loss and the general characteristics of all participants, and thechi-square test was applied to categorical data. Second, a logistic regression analysis was performed to determine the relevance of eight successfulweight loss methods based on the variables that can affect weight change such as age and sex. Similarly, a multivariate logistic regression analysisaimed to determine the correlation between mental health problems and successful weight loss. Results: The results showed that adhering to an appropriate dietary regime and taking oriental medicines significantly influenced weight reduction. Other methods such as skipping a meal, taking prescribed medicines or health supplements, and following a mono-diet have no noticeable effecton weight loss. Moreover, the analysis of factors affecting mental health that could influence the environment and lifestyle of the dieter hasindicated that there is no positive association between these factors and actual weight loss. Conclusion: A controlled diet is recommended as an effective treatment for weight loss rather than skipping a meal or fasting and taking orientalmedicine. The factors associated with weight loss may not cause mental health problems. 연구배경: 체중감량 성공을 거둔 사람들 간에 보이는 체중감량요법을 분석하고 체중감량을 하면서 발생된 것으로 생각되는 정신건강 문제에 대하여 알아보고자 연구를 시행하였다. 방법: 본 연구는 2016년 국민건강영양조사 제7기 자료를 바탕으로 조사 대상자의 일반적 사항에 대하여 설문을 통해 답변한 결과를 활용하였다. 일차적으로 전체 대상자들의 체중감량 성공 여부와 일반 특성 간의 연관성을 파악하고자 연속형 자료에 대해서 독립표본 t-검정을 적용하였고, 범주형 자료에 대해서 카이제곱검정(chi-square test)을 실시하여 본 연구의 의미성을 알아보고자 하였다. 두 번째로, 총 8가지의 체중감량 방식과 체중감량 성공 여부와의 관련성을 알아보고자 체중변화에 영향을 줄 수 있는 연령, 성별 등의 변수들을 보정하여 다변수 로지스틱 회귀분석(logistic regression analysis)을 시행하였고 같은 방식으로 정신건강상태와 체중감량 성공 여부와의 상호관계를 알아보고자 다변수 로지스틱 회귀순석을 시행하였다. 결과: 체중감량 성공과 이에 영향을 미친 체중감량요법에 대한 분석 결과 식이 조절 노력을 하거나 한약 복용을 했던 집단에서 체중감량 효과가 유의미하게 나타났으며 기타 방법인 단식, 결식, 운동 처방약복용, 건강기능식품 섭취, 원푸드 다이어트 등은 체중감량과의 관련성에 있어 무의미한 결과를 보였다. 또한 체중감량의 상황과 연관될 수 있는 정신건강요소와의 분석 결과에서는 6가지 항목들 중에서 어떠한 항목에서도 정신건강의 정도와 체중감량 성공 간의 유의미한 연관성을 찾기 어려웠다. 결론: 체중감량 성공에 효과적인 요법으로 결식, 단식보다는 식이 조절과 계획적인 한약제 복용이 추천될 수 있겠으며 체중감량 노력을 기울이는 동안 정신건강 면에서 문제를 발생시킬 수 있다는 결과를 도출하기는 어려워 보인다. 효과적인 체중감량요법과 정신건강문제의 상호관계에 대한 보다 활발한 연구가 필요할 것으로 생각된다.
Degradation of Limonene by Gamma Radiation for Improving Bioethanol Production
배형우,홍성현,박철홍,장동민,김태훈,정병엽 한국응용생명화학회 2014 Applied Biological Chemistry (Appl Biol Chem) Vol.57 No.1
Use of orange peel as a raw material for bioethanolproduction requires removal of its limonene content, whichinhibits fermentation. Orange peel was pretreated using electronbeam or gamma ray irradiation. Limonene content decreased in adose-dependent manner, with approximately 60% reductioncompared to the control after gamma irradiation at a dose of 800kGy. However, electron beam irradiation did not demonstrate thesame effectiveness. Therefore, gamma irradiation was deduced tobe a promising pretreatment method for removing limonene fromorange peel.
유기 발광 소자 디스플레이를 위한 적외선 램프 소스를 활용한 열 전사 픽셀 패터닝
배형우 ( Hyeong Woo Bae ),장영찬 ( Youngchan Jang ),안명찬 ( Myungchan An ),박경태 ( Gyeongtae Park ),이동구 ( Donggu Lee ) 한국센서학회 2020 센서학회지 Vol.29 No.1
This study proposes a pixel-patterning method for organic light-emitting diodes (OLEDs) based on thermal transfer. An infrared lamp was introduced as a heat source, and glass type donor element, which absorbs infrared and generates heat and then transfers the organic layer to the substrate, was designed to selectively sublimate the organic material. A 200 nm-thick layer of molybdenum (Mo) was used as the lightto- heat conversion (LTHC) layer, and a 300 nm-thick layer of patterned silicon dioxide (SiO<sub>2</sub>), featuring a low heat-transfer coefficient, was formed on top of the LTHC layer to selectively block heat transfer. To prevent the thermal oxidation and diffusion of the LTHC material, a 100 nm-thick layer of silicon nitride (SiN<sub>x</sub>) was coated on the material. The fabricated donor glass exhibited appropriate temperature-increment property until 249 ℃, which is enough to evaporate the organic materials. The alpha-step thickness profiler and X-ray reflection (XRR) analysis revealed that the thickness of the transferred film decreased with increase in film density. In the patterning test, we achieved a 100 μm-long line and dot pattern with a high transfer accuracy and a mean deviation of ± 4.49 μm. By using the thermal-transfer process, we also fabricated a red phosphorescent device to confirm that the emissive layer was transferred well without the separation of the host and the dopant owing to a difference in their evaporation temperatures. Consequently, its efficiency suffered a minor decline owing to the oxidation of the material caused by the poor vacuum pressure of the process chamber; however, it exhibited an identical color property.
Identification of γ-Radiation-responsive Proteins in Arabidopsis thaliana
정광우,이동기,조철오,이성범,김진홍,배형우,박용대,정병엽,이승식 (사)한국방사선산업학회 2019 방사선산업학회지 Vol.13 No.2
Due to an increase in public concern about radiation after the Fukushima nuclearaccident, an array of studies have been executed to understand the biological effects of radiationusing model organisms such as Arabidopsis rather than humans. Although a large amount ofinformation about the biological effect of radiation has been accumulated, most of the studieswere performed at the transcriptional level. To systematically understand the biological effects ofradiation, here, we performed proteome analysis using A. thaliana in the two vegetative stages [early(10-day-old) and late (21-day-old) vegetative stages] and identified radiation-responsive proteins. This analysis revealed that the proteins involved in the oxidative stress, molecular chaperone,and general stress responses showed an abundant change post γ-radiation exposure. Notably, weidentified four proteins (acryl carrier protein 4, glycine cleavage system H protein 1, peptidylprolylcis-trans isomerase CYP20-3, and calreticulin-1) that showed protein expression changes inboth early and late vegetative stages after γ-radiation exposure. Furthermore, the Gene Ontology(GO) analysis revealed that proteins changed post γ-radiation exposure were mainly involved inprotein binding activities and responses to stress. Collectively, we reported that proteins involvedin oxidative stress and molecular chaperones showed an abundant change in response to radiationexposure in the vegetative stage of the A. thaliana.
정병엽,Jae Taek Lee,이승식,김웅진,위승곤,배형우,조재영 한국응용생명화학회 2012 Applied Biological Chemistry (Appl Biol Chem) Vol.55 No.3
A significant challenge in biofuel production is the inefficient hydrolysis of lignocellulosic materials into simple sugar for conversion into fuel ethanol. This low efficiency results in part from lignin restricting the access of degradative enzymes to cellulose. Wheat straws exposed to electron beams ranging from 0 to 100 kGy were examined to determine effect of divided irradiation (25 kGy in 4 tandem doses) vs. single irradiation (100kGy). Yields of reducing sugars such as glucose and xylose after divided irradiation (51.1%) showed only a small increase relative to the control (40.9%), whereas in single irradiation, the yields of reducing sugars substantially increased to 74.9%. Results of X-ray diffraction showed crystallinity of cellulose slightly decreased from 43.0 to 38.8% after divided irradiation. Significant decrease to 34.1% was observed after single irradiation. Removal of hemicelluloses and modification of lignin polymer were also observed. These results indicate electron beam irradiation has destructive influence on both physical and chemical properties of wheat straw, thereby increasing accessibility of the cellulose surface to enzymatic hydrolysis and theoretically enable more efficient cellulose hydrolysis. Moreover, divided irradiation did not show a significant influence on enzymatic hydrolysis; hence,the single irradiation process is more effective than divided irradiation for increasing hydrolysis efficiency.
유기전자소자 적용을 위한 저온 공정용 배리어 박막 연구
Junmo Kim,이동구,이원호,Myungchan An,Youngchan Jang,배형우 한국센서학회 2019 센서학회지 Vol.28 No.6
Recently, semiconducting organic materials have been spotlighted as next-generation electronic materials based on their tunable electrical and optical properties, low-cost process, and flexibility. However, typical organic semiconductor materials are vulnerable to moisture and oxygen. Therefore, an encapsulation layer is essential for application of electronic devices. In this study, SiNx thin films deposited at process temperatures below 150 °C by plasma-enhanced chemical vapor deposition (PECVD) were characterized for application as an encapsulation layer on organic devices. A single structured SiNx thin film was optimized as an organic light-emitting diode (OLED) encapsulation layer at process temperature of 80 °C. The optimized SiNx film exhibited excellent water vapor transmission rate (WVTR) of less than 5 ×10-5g/m2 ·day and transmittance of over 87.3% on the visible region with thickness of 1 µm. Application of the SiNx thin film on the top-emitting OLED showed that the PECVD process did not degrade the electrical properties of the device, and the OLED with SiNx exhibited improved operating lifetime