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배중호 ( Joong Ho Bae ),한동수 ( Dong Soo Han ),김종표 ( Jong Pyo Kim ),백창희 ( Chang Hee Baek ),정용우 ( Yong Woo Chung ),전용철 ( Yong Cheol Jeon ),손주현 ( Joo Hyun Sohn ) 대한장연구학회 2005 Intestinal Research Vol.3 No.1
목적: 성인 남성과 폐경기 여성에서 철결핍 빈혈의 가장 흔한 원인은 위장관 출혈이며, 출혈 관련 위장관 병변을 발견하기 위해 상, 하부 위장관내시경을 사용한다. 이번 연구는 철결핍빈혈이 있는 환자에서 위장관 내시경 검사를 통해 진단된 위장관 질환의 임상적 특징과 출혈 연관 병변에 대한 예측인자를 알아보고자 하였다. 대상 및 방법: 2001년부터 2004년까지 철결핍빈혈로 진단 받은 189명의 의무기록을 후향적으로 조사하였다. 이들 가운데 상, 하부 위장관 내시경을 시행한 78명의 환자들을 대상으로 하였다. 현성 출혈이 있거나 소화기계 이외의 다른 원인에 의한 빈혈을 가진 경우는 제외하였다. 결과: 총 78명 환자의 평균연령은 49.3세였고 남녀 비는 1:2.7이었으며, 27.7%에서 출혈 연관 병변을 가지고 있었다. 상부위장관 내시경검사에서 확인된 출혈 연관 병변은 소화성 궤양(13.6%), 미란 위십이지장염(12.6%), 위암(5.1%)의 순이었고, 하부위장관내시경검사에서는 대장 용종(11.5%), 염증성 장질환(6.4%), 대장암(3.8%)의 순이었다. 출혈 연관 병변이 있는 환자들의 경우 평균 연령은 54.8세로 병변이 없는 환자들의 평균 연령 43.7세에 비해 의미 있게 높았고(p=0.026), 출혈연관 병변이 있는 환자들의 세망세포비(reticulocyte count)는 2.8%로 없는 환자군의 2.0%에 비해 의미 있게 높았다(p=0.002). 하지만 혈색소, 평균적혈구용적(mean corpuscular volume, MCV), 혈청 철, 페리틴(ferritin), 총철결합능(total iron binding capacity, TIBC)과 상, 하부 위장관 증상의 동반 여부 등은 두 군 간에 차이가 없었다. 결론: 이번 연구에서 상, 하부 위장관 내시경을 통해 발견된 철결핍빈혈 관련 위장관 병변들 중 상부위장관 질환의 유병률이 높았으며 위암이 대장암보다 많이 발견되었다. 고령이거나 세망세포비가 높을수록 출혈 연관 병변을 가지고 있는 경향이 있었다. 향후 국내 실정에 맞는 철결핍 빈혈 관련 위장관 질환의 예측인자를 찾기 위한 대규모 전향적 연구가 필요하다. Background/Aim: Gastrointestinal blood loss is the most common cause of Iron Deficiency Anemia (IDA) in men and postmenopausal women. Thus, esophagogastroduodenoscopy and colonoscopy are widely used to examine the gastrointestinal tract, in search for the cause of IDA. The purpose of this study was to identify clinical and biochemical variables that predicted the outcome of endoscopic findings in patients with IDA. Methods: Patients diagnosed as IDA from 2001 to 2004 were referred and retrogradely analyzed using their clinical, biological, endoscopic, and histological data. Results: 78 patients (21 men, 67 women: mean age 49.3 years) with IDA were enrolled, and 28.9% of patients had bleeding-related lesions. The mean age of patients with evidence of bleeding was 54.8 years, which was significantly higher compared with 43.7 years of the non-bleeding group (p=0.026). The reticulocyte count for the bleeding-related group was 2.8%, which was also significantly higher compared with 2.0% of the non-bleeding group (p=0.002). Conclusions: The prevalence of upper GI lesions were higher than lower GI lesions. Endoscopy revealed a source of IDA in 28.9% of cases. For hospitalized patients with IDA, endoscopy should be recommended to those older than 60 years of age, and those with increased reticulocyte count. (Intest Res 2005;3:68-73)
메티실린 저항성 포도상구균 장염 후 발생한 림프구 장염 1예
배중호 ( Joong Ho Bae ),한동수 ( Dong Soo Han ),박혜선 ( Hye Sun Park ),현일식 ( Yil Sik Hyun ),김태엽 ( Tae Yeob Kim ),은창수 ( Chang Soo Eun ),전용철 ( Yong Cheol Jeon ),손주현 ( Joo Hyun Sohn ) 대한장연구학회 2011 Intestinal Research Vol.9 No.2
Staphylococcus aureus (S. aureus) is occasionally a normal inhabitant of the gastrointestinal tract, and rarely considered a cause of enterocolitis. Methicillin-resistant Staphylococcal enterocolitis may cause persistent diarrhea leading to severe complications and even death, without appropriate treatment. Lymphocytic colitis (LC), a subtype of microscopic colitis, is a relatively common cause of chronic watery diarrhea. We report the case of a 73-year-old woman with profuse watery diarrhea caused by methicillin-resistant S. aureus. Soon after treatment of her enterocolitis with vancomycin the patient`s general condition and symptoms improved, although the diarrhea persisted. Through colonoscopic biopsy and immunohistochemical staining, overt LC was diagnosed, and prompt therapy with budesonide was initiated. (Intest Res 2011;9:139-143)
박지민,김다은,김해빈,배중호,이예지,명재인,황은경,임태은,송준호,유지상,류지헌,Park, Ji Min,Kim, Daeun,Kim, Hae Bin,Bae, Joong Ho,Lee, Ye-Ji,Myoung, Jae In,Hwang, Eunkyoung,Yim, Taeeun,Song, Jun Ho,Yu, Ji-Sang,Ryu, Ji Heon 한국전기화학회 2016 한국전기화학회지 Vol.19 No.3
리튬이온 이차전지의 고용량화를 위해 high-Ni계 양극 활물질이 크게 주목받고 있으나, Ni 함량이 높아짐에 따라 고온 안정성이 감소하여 수명저하가 발생하게 된다. 본 연구에서는 $LiNi_{0.6}Co_{0.2}Mn_{0.2}O_2$ (NCM622)의 합성공정 중에서 전구체인 전이금속 수산화물과 리튬염의 열처리 과정에 알루미나 입자를 첨가함으로써 추가적인 표면처리 공정없이 활물질 특성을 개선시키고자 하였다. 알루미나를 첨가하게 되면 고온 사이클 수명이 개선되었으며, 특히 나노크기의 알루미나를 사용하는 경우에 초기용량의 감소도 적고 수명도 개선됨을 확인하였다. 그리고, 나노 알루미나를 함량별로 추가한 결과로 표면형상이 점차 변화함과 동시에 격자상수의 감소가 발생하는 것이 관찰되어 표면코팅과 구조 내 치환이 동시에 발생하고 있음을 확인하였다. LSTA (linear-sweep thermmametry)를 사용하여 알루미나의 함량이 증가할 수록 부반응이 감소하며 고온 안정성이 증가하는 것을 확인하였다. 또한 전이금속 대비 Al을 2.5 mol% 추가하는 경우에 가장 우수한 고온 사이클 성능이 나타나는 것을 확인하였다. High Ni content layered oxide materials for the positive electrode in lithium-ion batteries have high specific capacity. However, their poor electrochemical and thermal stability at elevated temperature restrict the practical use. A small amount of $Al_2O_3$ was added to the mixture of transition metal hydroxide and lithium hydroxide. The $LiNi_{0.6}Co_{0.2}Mn_{0.2}O_2$ was simultaneously doped and coated with $Al_2O_3$ during heat-treatment. Electrochemical characteristics of modified $LiNi_{0.6}Co_{0.2}Mn_{0.2}O_2$ were evaluated by the galvanostatic cycling and the LSTA(linear sweep thermmametry) at the constant voltage conditions. The nano-sized $Al_2O_3$ added materials show better cycle performance at elevated temperature than that of micro-sized $Al_2O_3$. As the added amount of nano-$Al_2O_3$ increased, the thermal stability of electrode also enhanced, but the use of 2.5 mol% Al showed the best high temperature performance.
이정기(Jung-Ki Lee),배중호(Joong-Ho Bae),권해붕(Hae-Boung Kwon) 한국자동차공학회 2012 한국자동차공학회 학술대회 및 전시회 Vol.2012 No.11
Currently there is a standard of fuel economy for heavy duty vehicle in korea MLTM. But this test method is static speed method(60km/h). Hybrid and Electric vehicle have special functions, which are regeneration brake system and dual energy sources to improve the fuel economy. So It is necessary to amend the vehicle safety standard on heavy duty fuel economy that apply the characters of Hybrid and Electric vehicle. I will research the speed pattern of national road and world wide test cycle, which ETC, HHDDT, JE05 and WHVC. and I will measure fuel economy of the combined road which are urban, rural and motorway In addition I will measure the fuel economy of the average speed of real road consistent with average speed of WHVC. Also, I will measure the possibility of tracement, fuel economy by difference of start temperature and Mileage per charge on WHVC using electric buses.
박준성 ( Joon Sung Park ),정성진 ( Sung Jin Chung ),배중호 ( Joong Ho Bae ),김태종 ( Tae Jong Kim ),오승일 ( Seung Il Oh ),박재홍 ( Jae Hong Park ),엄완식 ( Wan Sik Uhm ),이혜순 ( Hye Soon Lee ),전재범 ( Jae Bum Jun ),정성수 ( Sun 대한류마티스학회 2003 대한류마티스학회지 Vol.10 No.1
Objective: We evaluated the clinical characteristics of tuberculous arthritis in peripheral joints and their relationship with rheumatologic disorders or other chronic illnesses. Methods: One hundred and sixty seven patients who had suffered from skeletal tuberculosis were treated at Hanyang university medical center from January 1993 to December 2000. We retrospectively analyzed 39 patients who were diagnosed as tuberculous arthritis in peripheral joints. Results: Thirty-nine (21 males, 18 females) patients with tuberculous arthritis in peripheral joints, aged 38.13±15.28, were found. All except one had a mono-articular feature. Affected joints were knee in 22 (56.4%), hip in 7 (17.9%), and wrist in 3 (7.7%). Extra-articular tuberculosis was noticed in 18 (46.2%) patients: lung involvement in 13 (33.3%), spine involvement in 4 (10.3%) and epididymis involvement in 1 (2.6%). One or more predisposing factors were found in 13 (33.3%) patients: 10 patients had a previous trauma history and 3 patients with previous intra-articular injections. Predisposing systemic conditions were present in 12 (30.8%) patients: 4 rheumatoid arthritis, 2 systemic lupus erythematosus, 1 juvenile rheumatoid arthritis, 4 liver cirrhosis, 2 breast cancer and 1 diabetes mellitus. Conclusion: Tuberculous arthritis in peripheral joints were evident in weight bearing joints, such as knee and hip, and were frequently associated with predisposing local or systemic factors. It is most important for the physician to make an early diagnosis and perform adequate treatments to prevent further complications.