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      • KCI등재

        ISSUES WITH A CHAINED-TYPE PRICE INDEX: AN ANALYSIS WITH THE PRODUCER PRICE INDEX

        박철범,류덕현 중앙대학교 경제연구소 2011 Journal of Economic Development Vol.36 No.3

        Regarding the recent switch from the fixed base price index to the chained-type price index in many countries, we examine important issues including the selection of the weight to produce more accurate chained-type price indices and to maintain statistical consistency in the time series of a price index in this study. We determine that the actual weight from year t-3 data better produces a more correct chained-type producer price index at t between two available methods of selecting the weights. This weighting method also provides generally better statistical consistency and stability for the chained-type producer price index. We also compare the MAE and RMSE of the price equations of the fixed base and chain indices. Both the unit root test and comparison of the model performance evaluation reveal no critical difference, thus confirming a stability over the two indices. In particular, the substitutability of the chain index for the fixed base index is highly obtained, regardless of the time horizon. Overall, we can confidently assert that the chain index provides a statistical consistency and stability over a fixed base index.

      • KCI등재

        Demographic Structure and Financial Markets in Korea

        박철범,김동헌 한국경제연구학회 2012 Korea and the World Economy Vol.13 No.2

        This paper examines the relationship between the demographic structure and asset prices in Korea based on the standard life-cycle model. To this end, this paper employs a non-parametric model which has an advantage of no functional form for the relationship a priori. We find that the estimated relation between the real interest rate and population density function is consistent with the implication from life-cycle models, whereas the relation between the normalized stock price and population density function is not. The projection based on the projected population estimates indicates that the real interest rate is going to rise until the 2020 due to the increase trend of old consumers and their dissaving behavior after the retirement.

      • KCI등재

        자궁 근종과 정상 자궁근층에서 Exon 5 가 결손된 에스트로겐 수용체 mRNA 의 발현 양상

        박철범,박원일,고덕성,이호준 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.4

        목적: 에스트로겐은 여러 에스트로겐 의존형 종양에서 그 성장에 관여하며, 정상 조직과 에스트로겐 의존성 종양에 다양한 종류의 에스트로겐 수용체가 존재한다는 실험결과가 기존에 많이 나와 있다. 최근에는 Exon 5 결손 에스트로겐 수용체 (D5-ER)가 많은 에스트로겐 의존형 종양에서 발견되었다. 본 연구에서는 자궁 근종과 D5-ER사이의 상호관계를 규명하고자 하는 것이 목적이다. 연구방법: 12명의 자궁 근종 환자와 12명의 대조군 에서 얻은 자궁근육층과 자궁 근종 조직에서 RT-PCR 을 이용해 D5-ER mRNA 와 wild type 에스트로겐 수용체(WT) mRNA의 상대적인 양을 측정하였다. WT/D5-ER 비율과 나이와의 상관관계도 측정하여 보았다. 결과: WT/D5-ER 의 값은 자궁근종 환자의 정상 자궁근층에서는 6.81±1.18 자궁근종에서는 6.40±1.20 으로 나타났고 대조군의 자궁 근층에서는 6.57±0.91로 나타나서 대조 군과 자궁근종 군, 자궁근종과 정상 자궁근층 사이에 통계학적 차이는 나타나지 않았다. 정상 자궁 근층내의 WT/D5-ER값과 나이의 상관관계를 조사하였으나 두 값 사이의 상관관계는 발견할 수 없었다 그러나 자궁 근종 조직내의 WT/D5-ER과 나이와의 상관관계를 조사해 본 결과 Rs= -0.789, p=0.002로 음의 상관관계를 나타내었다 결론: D5-ER은 대부분의 여성에서 흔히 일어나는 돌연변이이며 이는 자궁 근종의 생성과는 관계가 없는 것으로 여겨진다. 그러나 자궁근종내의 D5-ER은 자궁 근종의 성장과 관련이 있을 가능성이 있다. Objective: There is a large and increasing body of experimental and clinical data supporting the existence of variable estrogen receptors in both normal and neoplastic estrogen target tissue. Recently, exon 5 deleted estrogen receptor(D5-ER) has been identified in many estrogen dependent tumors. The purpose of this study is to assess the relationship between uterine myoma and D5-ER. Methods: The relative amount of wild type estrogen receptor mRNA and D5-ER mRNA were examined in human myometrium and myoma tissue obtained from 12 myoma patients and 12 control subjects by RT-PCR. The correlation between WT/D5-ER ratio and age was also evaluated. Results: There was no difference in expression of D5-ER mRNA not only between myoma and myometrim of the myoma patients, but also between myometrium of myoma patients and normal subjects. No significant correlation was found between D5-ER expression and age of the subjects in myometrial tissue. However, we could find negative correlation between WT/D5-ER ratio and age in myoma tissue. Conclusion: Upon these data, we conclude that D5-ER is a common variant mutation of estrogen receptor, which is not related with development of myoma. However, in myoma tissue, there is possibility that D5-ER may act some role in the growth of tumor.

      • KCI등재

        Various Expression of p63 in Ameloblastomas

        박철범,박경주,이종헌 대한구강악안면병리학회 2012 대한구강악안면병리학회지 Vol.36 No.3

        Several recent studies have detected genetic and cytogenetic alterations in epithelial odontogenic tumors. However, the detailed mechanisms of oncogenesis, cytodifferention, and tumor progression remain unknown. p63 as p53 homolog gene has been identified at loci 3q27-29. The p53 signaling cascade has an important role in oncogenesis or cyto- differentiation of odontogenic epithelium. Recently, several syndromes associated with p63 gene mutations have shown to include various tooth abnormalities of both the primary and permanent dentition. But little is known about p63 expression in odontogenic tumors, especially ameloblastomas. The purpose of this study were to examine various expression of p63 in ameloblastomas by immunohistochemistry and to clarify the possible biological role of p63 in ameloblastomas. 15 specimens including 6 follicular, 4 plexiform, 3 acanthomatous, and 2 granular cell types were fixed in 10% neutral formalin. 4um thick sections were used for routine H&E and immunohistochemical examinations. After immuno-histochemical satining, they were examined at a final magnification of 400X. For each case a minimum of 1000 nuclei located in the central and peripheral layers were counted in up to 10 consecutive microscopic fields per case. The immunoreactive cells were evaluated semiquantitatively. Immunoreactivity for p63 in all the types of ameloblastomas was higher in peripheral neoplastic cells than in central neoplastic cells. Keratinizing cells in acanthomatous ameloblastoma and granular cells in granular cell ameloblastoma showed markedly decreased reactivity for p63 in acanthomatous and granular cell ameloblastoma. Labelling index of acanthomatous,plexiform, and granular cell type was 86±11%, 81±17% and 83±15% in peripheral area while 88±14%, 82±11% and 76±10% in central area, respectively. Labelling index of follicular type was 17±4% in peripheral area while 21±3% in central area. There was no significant relationship between plexiform, acanthomaous, and granular cell type, while significant relationships between follicular and acanthomatous type, between plexiform and follicular type, and between granular cell and follicular type, respectively. It suggested that p63 expression could paly an important role in the pathogenesis of ameloblastomas. Morever plexiform, acanthomatous,and granular cell type would show more aggressive proliferative potentiality than follicular type.

      • Asset Prices, Heterogeneous Expectations, and Limited Short Sales

        박철범 고려대학교 미래성장연구원 2016 미래성장연구 Vol.2 No.1

        This paper extends the Harrison-Kreps model by allowing limited short sales and finite wealth. The main results of this paper are: (1) investors always pursue short-term gains (or participate in single-period speculation) when perceiving heterogeneous expectations; (2) important properties of the equilibrium price in the Harrison-Kreps model still hold even when limited short sales and finite wealth are allowed; (3) an increase in short-sale costs raises the risky asset price; and (4) an increase in the dispersion of expectations about future dividends also raises the risky asset price when the risky asset is held by a minority of investors.

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