제언 - 건강한 작업장에 대한 인식 체계의 전환

박주형,Park, Ju-Hyeong 대한산업보건협회 2017 산업보건 Vol.349 No.-

환경 중의 엔도톡신 노출 및 건강에 미치는 영향

박주형,Park, Ju-Hyeong 한국환경보건학회 2014 한국환경보건학회지 Vol.40 No.4

Microbes such as bacteria, fungi, archaea, protists, and viruses are ubiquitous and people are exposed to them continuously. Endotoxin is a component of the outer membrane of Gram-negative bacteria and a potent proinflammaotry substance. When a person is exposed to environmental endotoxin, an innate immune response is initiated upon the initial recognition and this response produces various inflammatory mediators and recruits inflammatory cells to the exposed tissues. A purified chemical form of endotoxin is called lipopolysaccharide (LPS), and the lipid A portion of the molecule is a biologically active moiety. Exposure to endotoxin may result in various complex health effects depending on time, route, and dose of exposure, as well as host susceptibility. Gene-environment interactions play important roles in health effects of endotoxin exposure, e.g. development or aggravation of asthma. To accurately assess exposure to endotoxin in environmental or epidemiologic studies, methods of sampling, extraction, and analysis must be carefully selected since the selected methods may substantially affect analytical results and there is no internationally-agreed standard method to date. The lack of a standardized method hampers the establishment of exposure-response relationships. While an internationally-agreed health-based exposure limit does not exist, the Dutch Expert Committee on Occupational Safety recently recommended $90EU/m^3$ as a health-based occupational exposure limit. The current article reviews various scientific issues on how we measure environmental endotoxin and the health effects of endotoxin exposure.

실내환경에서 생물학적 인자에 대한 노출평가

박주형,Park, Ju-Hyeong 한국환경보건학회 2009 한국환경보건학회지 Vol.35 No.4

The Institute of Medicine of the National Academies of Science in the United States concluded in its 2004 report that excessive indoor dampness is a public health hazard and that its prevention should be a public health goal. Water damage in buildings, such as leaks from roofs, walls, or windows, may increase indoor moisture levels. Excessive dampness may promote microbial proliferation in indoor environments, increase occupants' exposure to microbial agents, and eventually produce adverse health effects in building occupants. Epidemiological studies to demonstrate the causal association between exposure to indoor microbial agents and health effects require reliable exposure assessment tools. In this review, I discuss various sampling and analytical methods to assess human exposure to biological agents in indoor environments, their strengths and weaknesses, and recent trends in research and practice in the USA.

한.미 FTA가 국내 기계산업에 미치는 영향 분석 및 연구기관의 대응방안

박주형,정태영,김재윤,김완두,Park, Ju-Hyeong,Jeong, Tae-Yeong,Kim, Jae-Yun,Kim, Wan-Du 재료연구소 2006 機械와 材料 Vol.18 No.4

국가경쟁력 강화를 위한 현장중심 기술인력 양성 방안

박주형,김정흠,Park, Ju-Hyeong,Kim, Jeong-Heum 재료연구소 1998 機械와 材料 Vol.10 No.4

溫水수도꼭지와 溫水에서 Legionella pneumoph ila 의 分離I同定

朴柱炯(Ju Hyeong Park),鄭文植(Moon Shik Zong) 한국환경보건학회 1988 한국환경보건학회지 Vol.14 No.1

A study was carried out to fmd distribution of Legionella Spp. in hot water supplying systems of buildings in Seoul. Water samples were taken from the hot water taps in three research institute buildings during the period from the 2nd to 27th February, 1987. And all of the three buildings were supplied with hot water from the same central hot water tank. GVPC BCYEa and blood agar were used for the isolation of Legionella pneumophila and slide agglutination test (SA T) was performed to identify their strain types. Main findings were as follows; 1. 44 samples taken from hot tap-water revealed 20% of positive culture and 44 samples taken from hot water spouts revealed 11% of positive culture. 2. The 78% of positive samples taken from hot water was obtained from 25 .1 oC-45.0oC te:mperature range. 3. Only, Legionella pneumophila serogroup 3 was identified and .most of them has been than 2μm in length. 4. The densities of the Le망onella pneumophila isolated from hot water samples were within the range of 1.0 x 102 to 1.1 X 103 CFU/Q and their densities isolated from hot water spouts were either 1 CFUjplate or 2 CFU/plate.

시각화를 통한 문학 텍스트 구체화 교육의 가능성 고찰

박주형(Park, Ju-hyeong),윤여탁(Yoon, Yeo-tak) 국어국문학회 2017 국어국문학 Vol.0 No.179

이 연구는 문학 텍스트를 매개로 이루어진 학습자의 시각화 경험이 문학 텍스트를 통해 환기된, 언표화되기 어렵거나 복잡 모호한 반응을 구체화하는 계기가 될 수 있다고 보고, 시각화를 통한 문학 텍스트 구체화 교육의 가능성을 문학‧미술 융합 교육의 관점에서 제시하였다. 사고의 측면에서 볼 때, 문학 텍스트를 매개로 이루어지는 시각적 표현은 텍스트가 환기시키는 이미지나 사상을 구조화하는 인지 작용의 결과이며, 문학 텍스트가 환기시키는 지각 경험에 부합할 때 유의미한 경험으로 축적될 수 있다. 또한 이 과정에서 소통되는 구상적이거나 추상적인 차원의 인식들은 시각적 표현을 조정하는 경험을 통해 보다 소통 가능한 것으로 발전할 수 있다. 한편, 시각화는 그것의 기호적・수사적 특성을 기반으로 문학 텍스트와 연결될 수 있는데, 다양한 시각화 양상 중 텍스트의 내용과 밀접한 관련성이 있으면서, 텍스트의 의미를 넘어서는 유의미한 정보를 포함하고 있는 것이 문학 텍스트의 구체화를 위한 계기를 마련해 줄 수 있다. 따라서 시각화를 통한 문학 텍스트의 구체화 가능성은 문학 텍스트의 이해 과정에서 학습자가 봉착할 수 있는 문제 상황과 조우할 수 있는 영역에서 보다 높아질 것으로 기대할 수 있다. 이러한 관점을 바탕으로 초등학생 학습자들의 시각화 양상을 살펴본 결과, 정서체험과 연관된 상황을 시각적으로 표현하거나, 대상들 간의 비유적 관계를 형상으로 표현하는 활동, 언어적 반응을 시각적 표현과 결합시키는 활동에서 그러한 구체화의 가능성을 확인할 수 있었다. 그러나 이러한 가능성을 높이기 위해서는 시각적 표현의 의도를 상세화하거나, 예시적인 모델을 비계로 제공하거나, 조형 원리에 대한 이해를 제고하는 등의 교육적 처치가 필요하다는 점 역시 확인된다. The learner"s visualization experience through literary text can be the medium for concreting the ambiguous or complex response which is evoked through the text. From this perspective, this study presented the possibility of concretization education of literary text through visualization from the point of view of literature-art convergence education. In terms of thinking, visual expression through literary text is the result of the cognitive process of structuralizing images or ideas that the text evokes. And it can be accumulated as a meaningful experience for reader when it is suitable for the sensory experience evoked by the literary text. In addition, the concrete or abstract level of awareness communicated in this process can be developed to be more communicative through experience of coordinating visual expression. Visualization can be linked to the literary text based on its symbolic and rhetorical characteristics. Among various visualization aspects, the aspect that contains meaningful information transcending the meaning of the text, as well as closely related to the content of the text, becomes a medium for the concretization of the literary text. Therefore, it is expected that the possibility of the concretization of the literary text through visualization will be higher in the area where the learner can encounter the problem situation in the understanding process of the text. Based on these perspectives, this study analyzed the visualization aspects of elementary school students and found out the possibility of concretization of literary text in activities of visually expressing contexts of emotional experiences, expressing the metaphorical relationships in a plausible form, and combining visual form with linguistic expression. However, in order to increase this possibility, it is also confirmed that educational instruction such as refining the intention of visual expression, providing an illustrative model as a scaffold, or understanding the formative principle is needed.

천연 진드기기피제 개발을 위한 블렌딩 에센셜오일의 진드기 기피효능에 관한 연구

박주형(Ju-Hyeong Park),김주림(Joo-Rim Kim),조인경(In-Gyeng Jo),김병수(Byeong-Soo Kim) 한국동물보건학회 2022 한국동물보건학회지 Vol.1 No.2

In this study, an experiment was conducted to measure the tick repellent efficacy through the synergy effect according to the type and ratio of blending essential oil. The subjects were adults and nymphs of the Haemaphysalis longicornis, and the repellent efficacy was measured using the filter paper bioassay method. Based on the past research, citronella oil, geranium oil, vetiver oil, and neem oil were selected as a single treatment experiment since their repellent efficacy was confirmed. The first experiment revealed that the repellent efficacy of citronella oil and geranium oil were high. Afterwards, in order to investigate the synergy effect on tick repellent efficacy, experimental group was consisted of neem seed oil (carrier oil) that was blended with citronella and geranium oil, at a ratio of 1:1, 2:1, and 17:3 (15%). Also, negative control group was composed of ethanol that was blended with citronella and geranium oil at the same ratio of experimental group. As a result, the blending of citronella and neem seeds showed higher repellent efficacy in all blending ratios than the blending of geranium and neem seeds. In adult ticks, blending ratio of citronella and neem seeds was 1:1 and 17:3, showed the most significant difference of repellent efficacy. In nymph ticks, when the blending ratio of citronella and neem seed was 1:1 and 17:3, the repellent efficacy was the same as that of the positive control commercial repellent. In conclusion, it was confirmed that both nymph and adults ticks showed higher repellent efficacy when blended than single treatment. In this study, the synergy effect of the blending of citronella and neem seeds on the tick repellent effect has a high potential to replace synthetic repellents.

공공언어 사용 실태 및 개선 방안 - 공공기관 누리집 언어를 대상으로 -

박주형 ( Park Ju-hyeong ) 한국공공언어학회 2020 공공언어학 Vol.3 No.0

본 논문에서는 공공기관 누리집에 있는 언어 자료를 대상으로 공공언어가 갖춰야 할 요건인 소통성과 정확성을 분석하였다. 이는 지난 2019년에 진행되었던 ‘지방자치단체 언어환경 대진단’ 자료를 바탕으로 이루어졌다. 먼저 ‘공공성’과 ‘정확성’을 진단 기준으로 삼아 누리집에 자주 등장하거나 많은 사람들이 접할 것으로 보이는 단어나 표현들에 주목하여 그것의 문제와 개선안을 함께 제시하였다. 그 결과 문장부호의 경우 연월일 표기 오류 사례가 많이 발견되었음을, 띄어쓰기 관련 오류 사례로는 쌍점 띄어쓰기, 3어절 이상의 단어를 모두 붙여써서 가독성이 떨어지는 사례가 있음을 제시하였다. 이밖에 외래어 사용 오류, 로마자 표기 오류 등의 문제점에 대해 실태조사 결과 발견되었던 실제 사례들을 중심으로 논의하였다. 다른 진단 기준이었던 ‘소통성’을 높이기 위해서는 정확한 단어나 표현뿐만 아니라 가능한 한 쉬운 단어들을 사용해야 한다. 최근 어려운 단어를 이용해 권위를 얻을 수 있다는 인식에서 벗어나 누구나 쉽게 이해할 수 있는 단어를 사용해야 한다는 목소리가 높아지고 있다. 또한 본 논문에서는 ‘소통성’은 ‘정확성’과의 경계가 뚜렷하게 구분되지 않는다는 점에 주목하였는데, 해당 단어나 문장이 보도 자료에 쓰인 것인지, 누리집의 막대광고(배너, banner)에 쓰인 것인지 등에 따라 성격이 다르기 때문에 공공언어마다 각 항목의 가중치를 달리하여야 한다는 것이다. 따라서 향후 공공언어 개선 방향과 남겨진 과제를 해결하기 위해서는 기존 진단 기준을 바탕으로 하되 규범과 실제 사용의 영역을 오가면서 경직된 규범 위주에서 벗어나 유연한 관점으로 바라볼 필요가 있다고 본다. This study examined the communication and accuracy of the languages shown on the Internet sites of public institutions. First, we took a closer look at the items of ‘community’ and ‘accuracy’ that we used to use as the basis for diagnosis. And we analyzed what the problems were and presented together with improvement plans, focusing on the popular public languages used in their websites. The discussion will be based on data on ‘Great Diagnosis of Language Environment for Local Governments’ that was conducted in 2019. As a result, errors in the use of punctuation marks, spacing errors, use of foreign words, and Romanization alone were summarized. In order to enhance the communication of public languages, we must use the words as easy as possible, as well as the exact words or expressions. Recently, more and more people are calling for the use of words that are easily understood by anyone, away from the perception that difficult words can be used to gain authority. In the future, public language will have to shift from rigid norm-oriented perspective to flexible perspectives, moving between diagnosing existing public languages and refining emerging public languages into and out of the norm and real areas of use.

Balb/c 마우스에서 초과 추출물의 3주간 반복 경구투여 독성평가

박주형 ( Ju Hyeong Park ),조영락 ( Young Rak Cho ),고혜진 ( Hye Jin Ko ),정원식 ( Wonsik Jeong ),안은경 ( Eun Kyung Ahn ),오준호 ( Junho Oh ),오좌섭 ( Joa Sub Oh ) 한국응용생명화학회(구 한국농화학회) 2015 Journal of Applied Biological Chemistry (J. Appl. Vol.58 No.2

본 연구는 다양한 효능을 지닌 초과(Amomum tsao-ko Crevostet Lemaire)의 안전한 이용을 위한 독성평가로 식품의약품안전처 고시 제2014-6호 ‘의약품등의 독성시험기준’에 맞는 독성시 험법에 따라 Balb/c mouse를 이용하여 3주간 반복경구투여를 통해 초과의 안전성을 확인하고자 하였다. 3주간 반복 경구투여 후 체중, 장기중량 측정, 혈액분석 및 혈액생화학 검사를 실시하여 안전성을 확인 한 결과, 초과에 의한 특별한 증상이나 체중, 장기중량의 변화는 관찰되지 않았으며, 복대동맥으로부터 채혈한 혈액을 통한 혈구분석결과에서도 대조군과 초과 추출물 투여군 간의 통계적인 유의성을 관찰 할 수 없었다. 또한 혈청을 이용하여 간기능(GOT, GPT, LDH, ALB, TP-S, T-BIL, DBIL), 신장기능(BUN, CRE), 지질영양 관련(TG), 전해질 관련 (I.P) 지표들의 생화학분석을 수행한 결과, 대조군과 유사하게 모두 정상 범위 내의 결과를 나타내었다. 이러한 결과를 통하여 초과 추출물의 최대무독성용량은 최고 투여량인 2000 mg/kg 이상으로 판단되며, 본 연구결과는 초과의 기능성 식품, 화장품, 의약품 등 다양한 소재로서의 활용에 안전성 관련 기초자료로 이용될 수 있을 것으로 사료된다. Abstract In the present study, we investigated the oral toxicity of Amomum tsao-ko Crevost et Lemaire, (Zingiberaceae) extract in Balb/c mice (BALB, n=60) for 3 weeks. Balb/c mice (10 mice/ group, 6 group, 20±2 g, 6 weeks) were orally administered for 21 days, with dosage of 250, 500, 1000, 2000 mg/kg/day. Ethanolextract of A. tsao-ko did not affect any significant change of mortality, clinical signs, organs and body weights. Also, there were not significantly difference from the naive group (control) in hematological and serum biochemical examination. Consequently, these findings indicate that 3-week treatment with the ethanol extract of A. tsao-ko was not any toxic effects in Balb/c mice and the no-observed adverse effect level (NOAEL) for oral toxicity was determined to be 2000 mg/kg/day under our experimental conditions.