유방의 악성 선근상피종(Adenomyoepithelioma) 증례 보고

박상협,이아원,송병주,오승택,오세정,김정수,정상설 대한외과학회 2004 대한외과학회 학술대회 초록집 Vol.2004 No.5

Amprolium hydrochloride 투여에 따른 넙치(Paralichthys olivaceus)의 독성 영향

박상협,최영광,도정완,최혜승,김이경 한국어병학회 2023 한국어병학회지 Vol.36 No.1

The aim of this study was to examine the effect of amprolium hydrochloride on olive flounder Paralichthys olivaceus. Thirty flounder (average weight 230.27 g; average length 27.99 cm) was randomly allocated into six groups, namely, 50, 100, 150, 200, 400 and 600 mg/kg. As measure of acute toxicity the LD50 value of 148.18 mg/kg was obtained. Hematologic analysis was performed on days 1, 3, 7, 14, and 28 after the intramuscular injection of the drug. Among the plasma biochemistry profiles, glutamic oxalate transaminase (GOT) activity and blood urea nitrogen (BUN) were found significantly increased. In addition, histopathology analysis revealed frequent appearance of melanomacrophage center (MMC) and edema in the renal tissues after 20, 40 and 80 mg/kg on day 7, 14, 28. In summary, amprolium exposure seem to cause adverse effects of flounders.

공유 구(common ostium)의 원위부 동-정맥루를 동반 시행한 하지 동맥 우회술

박상협,양근호,박순철,문인성,고용복 대한혈관외과학회 2003 Vascular Specialist International Vol.19 No.2

Functionalization of Carbon Molecular Sieve (CMS) by PEI and preparation of Pt/PEI-CMS as a catalyst in PEMFC

박상협,양희나,이동철,박경우,김화중 한국공업화학회 2013 한국공업화학회 연구논문 초록집 Vol.2013 No.1

LNG선 Ballast Tank Mud Flushing System의 최적설계

박상협,송유석,김영복,Park, Sang Hyeop,Song, Yoo Seok,Kim, Young Bok 대한기계학회 2016 대한기계학회 논문집. Transactions of the KSME. C, 산업기술과 혁신 Vol.4 No.2

LNG선의 발라스트 탱크에 해수를 유입할 때 해수에 부유하고 있는 해저면의 머드 입자가 탱크 안으로 유입되고 탱크내에 침전되는 문제가 발생한다. 탱크에서 해수를 배출 할 때에 침전된 머드를 함께 제거할 수 있도록 발라스트 탱크 내에 머드 플러싱 시스템을 적용하였다. 본 연구에서는 플러싱 시스템의 머드 제거 효과를 평가하기 위해 입자 크기 분석기를 통해 머드의 입자 크기를 측정 하였으며, 입자 크기와 전단 응력의 관계를 바탕으로 수치해석을 통해 머드의 부유 성능을 평가하였다. 탱크내 머드 플러싱 배관 시스템을 최적화하여 탱크내 머드 부유 성능을 극대화하였다. During ballast of a LNG carrier, the mud at the sea floor can enter the tanks together with the ballast water if the LNG terminal is located at shallow water region. In order to remove the mud deposited on the tank floor during deballasting, the mud flushing system in the ballast tanks is applied. In this study, various analyses to conform the efficiency in the mud removal are performed. In order to design the mud flushing system, the particle size of the mud is measured by particle size analyzer. Flushing performance is evaluated by numerical analysis. From the results of numerical analysis including flow field and piping system network, the optimized flushing system is determined.

안면 손상의 위치와 외상성 뇌 출혈과의 관계

박상협,한승백,서영주,강 수,김아름,이형민,김아진 대한응급의학회 2016 大韓應急醫學會誌 Vol.27 No.6

Purpose: Several studies have reported that facial fractures were associated with traumatic brain injuries or cervical injuries. The purpose of this study was to analyze the relationship between the location of facial injury and traumatic brain hemorrhage in order to support future decisions for image evaluation in facial injury patients. Methods: In this retrospective cohort study, we evaluated facial injury patients without external head trauma who visited the emergency department at our hospital between January 1, 2014 and October 31, 2014. We divided the cohort into 2 groups: Facial injury patients with associated traumatic brain hemorrhage and those without traumatic brain hemorrhage. We compared the factors related to traumatic brain hemorrhage, such as facial injury locations, mechanism of accident, types of wounds, altered mentality, headache, and loss of consciousness between the two groups. Results: In 873 patients, 73 (8.36%) presented traumatic brain hemorrhage and the other 800 had no traumatic brain hemorrhage on a brain computed tomography (CT) scan. The rate of headache, loss of consciousness, altered mentality, traffic accident, fall down, fracture, temporal injury, frontal injury, multiple facial area injury, and upper facial area (frontal and upper orbital area) injury were higher in the traumatic brain hemorrhage group than in the non-traumatic brain hemorrhage group (p<0.05). The risk factors of traumatic brain hemorrhage were headache, loss of consciousness, altered mentality, facial bone fracture, and temporal area injury of the face. Conclusion: If a facial injury patient has any of the following factors temporal area injury, facial bone fracture, altered mentality, headache, and loss of consciousness, we have to evaluate the brain CT scan even if the patient had no external head injury.

SMCS, 환경성과, 그리고 경영성과 간의 관계

박상협,이상완 한국회계정보학회 2020 회계정보연구 Vol.38 No.4

[Purpose]Despite the recent SMCS study to address sustainability issues, the results of its research on the methods of use and performance of SMCS have been mixed. It can be pointed out that the reasons for the mix were limited in view of how SMCS was used and that the performance was not clearly classified at various levels. The purpose of this study is to examine the relationship between the methods of use of SMCS and to provide a broader understanding of the relationship between SMCS, environmental performance, and business performance. [Methodology]To achieve the purpose of this study, a questionnaire is distributed to executives of 400 domestic manufacturing companies, and a total of 97 questionnaires are used for statistical analysis. The hypothesis test is tested with the path coefficient of the structural model using PLS. [Findings]There was a significant positive(+) relationship between the use of SMCS. The use of SMCS was found to have a partially significant positive(+) relationship between environmental performance and management performance. In addition, environmental performance did not appear to have a significant relationship with management performance. [Implications]It is meaningful that the empirical analysis of SMCS, which is presented as a tool to support the recent issue of sustainability management, is significant. It is suggested that managers should consider the complementary relationship between control systems and use it elaborately to ultimately improve environmental performance and business performance. [연구목적]최근 지속가능성 이슈를 해결하기 위한 SMCS의 연구에도 불구하고 SMCS의 이용방식과 성과에 대한 연구결과는 혼재되었다. 혼재된 원인으로는 SMCS 이용방식에 대한 시각이 제한적이었으며, 성과를 다양한 차원에서 명확하게 분류하지 않았다는 점을 지적할 수 있다. 본 연구의 목적은 SMCS의 이용방식간의 관계를 살펴보고 SMCS, 환경성과, 그리고 경영성과간의 관계를 고려하여 이들간의 관계에 관한 보다 폭넓은 이해를 제공하는 데 있다. [연구방법]본 연구의 목적달성을 위해 국내 400대 제조기업의 임원들을 대상으로 설문지를 배포 및 회수하여 총 설문지 97부가 통계분석에 사용되었고 가설검정은 PLS를 이용하여 구조모형의 경로계수로 검정하였다. [연구결과]SMCS 이용간에는 유의한 정(+)의 관계가 있는 것으로 나타났다. SMCS의 이용은 환경성과와 경영성과에 부분적으로 유의한 정(+)의 관계가 있는 것으로 나타났다. 또한 환경성과는 경영성과에 유의한 관계가 없는 것으로 보여졌다. [연구의 시사점] 최근 이슈인 지속가능경영을 지원할 수 있는 도구로 제시되고 있는 SMCS를 실증분석하였다는데 의의가 있다. 경영자들은 통제시스템들간의 상호보완적인 관계를 고려하여 이를 정교하게 사용해야 궁극적으로 환경성과 및 경영성과를 증진시킬 수 있음을 시사하고 있다.

AEBS와 LDWS가 장착된 대형버스의 정기검사를 위한 검사요소 개발

박상협,한종호,윤윤기,이태희,이호상,강병도,Park, Sanghyeop,Han, Jongho,Yoon, Yoonki,Lee, Taehee,Lee, Hosang,Kang, Byungdo 한국자동차안전학회 2021 자동차안전학회지 Vol.13 No.2

In this paper, we proposes a study on the derivation of inspection factors for the periodic inspection of large buses equipped with AEBS and LDWS. we investigate the safety evaluation (NCAP) of domestic and foreign vehicles and safety standards for the two functions currently in operation and analyze the evaluation factors, measurement methods and evaluation scenarios and so on. In addition, the test scenario was derived by analyzing the vehicle safety evaluation data already held, Therefore, we use an real large bus and the inspection elements for the periodic inspection were derived.

인적자본 지속가능성 리더십, SMCS, 그리고 지속가능 성과간의 관계

박상협,이상완 한국경영학회 2022 經營學硏究 Vol.51 No.3

Recently, companies are striving to solve complex economic, environmental, and social issues required by various stakeholders. In order to solve these issues and achieve sustainability performance, human capital sustainability leadership plays an important role, and SMCS is proposed as a means of effectively and efficiently implementing managerial leadership. Therefore, in this study, considering human capital sustainability leadership, we intend to empirically analyze SMCS and sustainability performance in one framework. As a result of analysis, First, human capital sustainability leadership was found to have a significant positive effect on sustainability performance. Second, human capital sustainability leadership was found to have a significant positive effect on the use of SMCS. Third, SMCS was found to have a significant positive effect on sustainability performance. The results of this study show that various managerial leadership, that is, human capital sustainability leadership, is needed to solve recent various and complex issues, and that sustainability performance can be achieved by considering the relationship between SMCS usage methods. This suggests that unlike in the past, managers are required to have complexity leaderships, and these managers must use processes such as systems built in companies in an integrated and organic manner.

Helicobacter pylori 감염과 Interleukin $1\beta$ 유전자의 다형성에 따른 위암 발생 위험도

박상협,송교영,김진조,진형민,김욱,박조현,박승만,임근우,박우배,김승남,전해명,Park, Sang-Hyub,Song-Kyo-Young,Kim, Jin-Jo,Jin-Hyung-Min,Kim, Wook,Park, Cho-Hyun,Park, Seung-Man,Lim-Keun-Woo,Park, Woo-Bae,Kim, Seung-Nam,Jeon, Hae-Myung 대한위암학회 2004 대한위암학회지 Vol.4 No.3

Purpose: According to the recent studies, it is shown that the polymorphism of Interleukin $1\beta$ gene is associated with the incidence of gastric cancer caused by the Helicobacter pylori infection. Interleukin $1\beta$ is a cytokine markedly inhibiting gastric acid secretion. Interleukin $1\beta$ production associated with Helicobacter pylori gastric infection may exacerbate mucosal damage including chronic gastritis and atrophic gastritis, may induce eventual neoplasia. Among these Interleukin $1\beta$ gene polymorphisms, polymorphisms at -31 portion and -511 portion may associated with these processes, eventually increase the risk of gastric cancer. We investigated the risk of gastric cancer according to the Helicobacter pylori infection and genetic polymorphism of Interleukin $1\beta$ in gastric cancer patients. Materials and Methods: 176 individuals with gastric cancer and 40 healthy controls were analyzed. Each group was divided into two groups whether they infected with Helicobacter pylori or not. DNA was extracted from the peripheral blood in all groups. The PCR-RFLP method was used for investigating the distribution of genotype of C/C, C/T, T/T at -31 portion and -511 portion. Results: T/T genotype at -511 portion was $19.3\%$ in gastric cancer cases and $10\%$ in controls, which was statistically significant. (P=0.0432) The risk of gastric cancer was increased 4.86 ($1.26\∼18.77$) in group which had T/T genotype. In gastric cancer cases, C/C genotype at 31 portion was $27.6\%$ in group with Helicobacter pylori infection and $12.8\%$ in group without infection, which was statistically significant. (P=0.0047) The risk of gastric cancer was increased 4.82 ($1.81\~12.81$) in group which had C/C genotype. Conclusion: T genotype at -511 portion among the Interleukin $1\beta$ genetic polymorphisms may be the risk factor of gastric cancer. And, with Helicobacter pylori infection, C genotype at -31 portion may be the risk factor of gastric cancer.