http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
SIP RFC 3261과 H.323 표준에 부합하는 멀티미디어 단말기의 설계 및 구현
박보미,성동수,이건배 경기대학교 부설 산업기술종합연구소 2003 산업기술종합연구소 논문집 Vol.26 No.-
본 논문에서는 인터넷 환경에서의 영상회의 표준인 IETF의 SIP와 ITU-T의 H.323을 모두 만족하는 멀티미디어 단말기를 설계하고 구현한다. 현재 개발된 영상회의 시스템은 SIP 또는 H.323만을 지원하고 있으며, 두 표준을 지원하는 시스템간의 상호 운용을 위해 SIP-H.323 게이트웨이가 필요하다. 그러나 게이트웨이의 표준 논의가 현재 진행 중이기 때문에 이와는 별도로 2개의 표준을 모두 지원하는 멀티미디어 단말기의 필요성이 대두되었다. 본 논문에서 구현된 멀티미디어 단말기는 SIP 및 H.323 표준을 모두 만족하도록 구현되었으며, 두 개의 프로토콜 지원으로 인한 시스템의 복잡도를 해결하기 위하여 공통 부분인 RTP/RTCP, 음성 및 영상 코덱 제어 부분을 통합하였다. 실험 결과로부터 본 시스템은 두 표준안을 만족함을 알 수 있다. In this paper, we have implemented the multimedia terminal supporting both IETF SIP and ITU-T H.323 for video-conference standards over internet environment. Because of supporting only SIP or H.323 in current video-conference systrms, interoperability between both standards is needed. Since SIP-H.323 gateway has been currently discussed for it, a video-conference system supporting two standards is necessary to be developed separately. The system implemented in this paper is satisfied with two standards, and has been designed for reducing the system comptexity on supporting two standards. The system uses maximally RTP/RTCP protocol, audio and video codec that is the common module of two sfandardizations. Consequently, we have known that the system is satisfied with two standards through expertments.
박보미,임승길,김은진,남희진,Dongdong Zhang,배주현,강명모,김희연,이원태,Bjarne Bogen 연세대학교의과대학 2017 Yonsei medical journal Vol.58 No.3
Purpose: Dickkopf 1 (DKK1) has been extensively investigated in mouse models of multiple myeloma, which results in osteolytic bone lesions. Elevated DKK1 levels in bone marrow plasma and serum inhibit the differentiation of osteoblast precursors. Presentpharmaceutical approaches to target bone lesions are limited to antiresorptive agents. In this study, we developed a cyclized oligopeptide against DKK1-low density lipoprotein receptor-related protein (LRP) 5/6 interaction and tested the effects of the oligopeptideon tumor burden. Materials and Methods: A cyclized oligopeptide based on DKK1-LRP5/6 interactions was synthesized chemically, and its nuclearmagnetic resonance structure was assessed. Luciferase reporter assay and mRNA expressions of osteoblast markers were evaluatedafter oligopeptide treatment. MOPC315.BM.Luc cells were injected into the tail vein of mice, after which cyclized oligopeptidewas delivered subcutaneously 6 days a week for 4 weeks. Results: The cyclized oligopeptide containing NXI motif bound to the E1 domain of LRP5/6 effectively on surface plasmon resonanceanalysis. It abrogated the Wnt-β-catenin signaling inhibited by DKK1, but not by sclerostin, dose dependently. RT-PCR and alkaline phosphatase staining showed increased expressions of osteoblast markers according to the treatment concentrations. Bioluminescence images showed that the treatment of cyclized oligopeptide reduced tumor burden more in oligopeptide treated group than in the vehicle group. Conclusion: The cyclized oligopeptide reported here may be another option for the treatment of tumor burden in multiple myeloma.
Factors Influencing Vaccination in Korea: Findings From Focus Group Interviews
박보미,최은정,박보현,한혜진,조수진,최희정,이선화,박혜숙 대한예방의학회 2018 예방의학회지 Vol.51 No.4
Objectives: Immunization is considered one of the most successful and cost-effective public health interventions protecting communities from preventable infectious diseases. The Korean government set up a dedicated workforce for national immunization in 2003, and since then has made strides in improving vaccination coverage across the nation. However, some groups remain relatively vulnerable and require intervention, and it is necessary to address unmet needs to prevent outbreaks of communicable diseases. This study was conducted to characterize persistent challenges to vaccination. Methods: The study adopted a qualitative method in accordance with the Consolidated Criteria for Reporting Qualitative Research checklist. Three focus group interviews were conducted with 15 professionals in charge of vaccination-related duties. The interviews were conducted according to a semi-structured guideline, and thematic analysis was carried out. Data saturation was confirmed when the researchers agreed that no more new codes could be found. Results: A total of 4 main topics and 11 subtopics were introduced regarding barriers to vaccination. The main topics were vaccine hesitancy, personal circumstances, lack of information, and misclassification. Among them, vaccine hesitancy was confirmed to be the most significant factor impeding vaccination. It was also found that the factors hindering vaccination had changed over time and disproportionately affected certain groups. Conclusions: The study identified ongoing unmet needs and barriers to vaccination despite the accomplishments of the National Immunization Program. The results have implications for establishing tailored interventions that target context- and group-specific barriers to improve timely and complete vaccination coverage.
ICAO의 ASBU(Aviation System Block Upgrades) 추진 동향(1)
박보미,김준혁,Park, Bomi,Kim, Jun-hyuk 한국항공운항학회 2016 한국항공운항학회지 Vol.24 No.2
Development of air navigation and avionics technologies led to solve the problems that conventional ATM system had. The International Civil Aviation Organization developed the Aviation System Block Upgrades (ASBU) initiative in order to harmonize global ATM planning and technology upgrades and urged to implement the recommendations for the member States. The ASBUs provide the road map to assist air navigation service providers in the development of their individual strategic plans and investment decisions. In this paper, the operational concepts in 2 performance improvement areas, Airport Operations and Globally Interoperable System and Data in ASBUs, have been summarized. In Airport Operations area the new management technologies and required systems are presented for optimizing the traffic flow in airport area and terminal airspace. Data format standards and required systems presented for information integration and usage of the new system under Globally Interoperable System and Data area.
박보미,Bharat Bhusan Patnaik,오승한,김동현,조용훈,정헌천,이용석,고기성,김익수,한연수 한국곤충학회 2013 Entomological Research Vol.43 No.5
The tumor suppressor, QM has been cloned and characterized from eukaryotic organisms including humans, vertebrates, invertebrates, plants and yeast. However, no study on Pieris rapae QM (PrQM) has been reported to date. In this study, cDNA encoding a putative QM protein (PrQM) was obtained from expressed sequence tags (ESTs) of the Pieris rapae cDNA library. Phylogenetic analysis of PrQM showed high similarity of amino acid sequence with other putative homologues identified from Heliothis virescens (95%), Bombyx mori (92%), Plutella xylostella (92%), Drosophila melanogaster (89%) and Polyrhachis vicina (85%), indicating that QM is highly conserved among insects. Semi‐quantitative PCR datasets revealed that PrQM transcripts are highly expressed in head, silk gland, integument and fat body, with pronounced expression observed during the egg stage. The coding region of the PrQM gene was cloned into the pET28 (+) expression vector and the recombinant protein purified by His‐tag affinity chromatography was used for antibody production. Western blotting with the anti‐PrQM antibody detected a single band corresponding to the expected molecular weight of both endogenous (26 kDa) and recombinant (29 kDa) PrQM. Furthermore, immunohistochemical and confocal microscopic analysis with the anti‐PrQM antibody showed that the QM gene is highly expressed in the cytoplasm of fat body, gut and Malpighian tubules in virus‐uninfected control larvae, but down‐regulated at 4 days post Pieris rapae granulovirus (PiraGV) infection. These data show that PrQM is negatively regulated upon virus infection and suggests a putative immunomodulatory function.
박보미 한국보건사회연구원 2012 보건복지포럼 Vol.192 No.-
노인의 기본 권리로서, 생활공간인 주거지와 교통환경의 안전성과 편리성이 보장되어야 할 것이며, 삶의 안전성 또한 보장되어야 할 것이다. 본 고에서는 2011년도 노인실태조사를 이용·분석하여, 노인의 주거환경 및 교통환경 그리고 삶의 안전성에 대해 실태를 파악 하였다. 그 결과, 주거·교통 환경에서 불편함을 겪고 있는 것으로 나타났으며, 삶의 안전성에서도 취약함이 발견되었다. 이에 고령친화 적이고 안전한 생활환경을 만들기 위한 지속적인 정책이 필요함을 알 수 있다. 나아가 제특성별로 생활환경에 있어 차이가 나타나, 취약층에 대한 세부적인 정책 역시 필요하다.