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민태훈(Taehoon Min),나형철(Hyungchul Na),김노유(Nohyu Kim) 한국비파괴검사학회 2011 한국비파괴검사학회지 Vol.31 No.2
위상잠금 적외선 열화상장치를 제어하기 위한 랩뷰(LabVlEW) 프로그램을 기본적인 적외선 열화상 하드웨어와 함께 개발하였다. 개발된 열화상 제어 프로그램은 열화상 카메라와 할로겐램프를 임의의 주기함 수로 동기화 시키면서 사이리스터 회로를 기반으로 랩뷰 소프트웨어에 의해 제어가 가능하도록 설계하였다. 개발된 프로그램은 스크린 메뉴 방식으로 구성되어 컴퓨터 화면에서 열원의 주기와 에너지, 적외선 카메라의 동작과 이미지 취득을 사용자가 자유롭게 변경하고 그 결과를 화면에서 확인할 수 있도록 제작되었다. 개발된 열화상 제어 프로그램과 장치를 이용하여 판재 내부의 원형인공결함의 이미지를 검사하여 광학 이미 지와 비교하였다. A LabVIEW program has been developed together with simple infrared thermography(IRT) system to control the lock-in conditions of the system efficiently. The IR imaging software was designed to operate both of infrared camera and halogen lamp by synchronizing them with periodic sine signal based on thyristor(SCR) circuits. LabVIEW software was programmed to provide users with screen-menu functions by which it can change the period and energy of heat source, operate the camera to acquire image, and monitor the state of the system on the computer screen. In experiment, lock-in IR image for a specimen with artificial hole defects was obtained by the developed IRT system and compared with optical image.
만성기침 환자에서 천명의 경험 유무에 따른 기침이형천식 진단율의 차이
이병재,민태훈,최동철 대한천식 및 알레르기학회 2004 천식 및 알레르기 Vol.24 No.1
Backgrond : Objective tests including the methacholine bronchial provocation test and the induced sputum examination are now crucial in the detection of causes of chronic cough. On the other hand, carefully taken history of characteristics, complications, or duration of cough are known not useful in diagnosing causes of chronic cough. Objectives : Patients with a history of cough lasting more than 3 weeks were enrolled. Patients who were current smokers, who had been receiving an angiotensin-converting enxyme inhibitor, who had basal EFV3 less than 70% of predicted value, who had adventitial sound on auscultation, or who had experienced resting dyspnea were all excluded. We divided the patients into two groups according to the ever wheeze history. The methacholine test (reference value of PC20 = 25㎎/㎖) and the induced sputum eosinophil percentile (reference value = 3%) were compared between the two groups. All patients were evaluated by an anatomic diagnostic protocol, and the prevalence of cough variant asthma was compared. Results : Three hundred eighty-two patients (138 males and 244 females) with mean age of 48.2 years met the inclusion criteria. The mean duration of cough was 30.4 months (range, 3 weeks to 600 months). Ever wheezers were 154 (40.3%), and non-wheezers were 228 (59.7%). Ever wheeze group showed higher positive methacholine test (37.7% vs. 14.5%, p<0.001) and increased sputum eosinophils (43.5% vs. 11.4%, F<.001) compared to non-wheeze group. The prevalence of cough variant asthma was significantly higher in ever wheeze group (33.8% vs. 6.1%, F<.001), and that of eosinophilic bronchitis showed similar result (13.6% vs. 4.8%. F<.01). The positive predictive value of the methacholine test was lower in non-wheeze group compared to ever wheeze group (42.4% vs. 86.2%, F<.01). Conclusion : Ever wheeze history might be very important in suspecting, cough variant asthma as a cause of chronic cough. In chronic cough patients without ever wheeze, prevalence of cough variant asthma and positive predictive value of methacholine test were low. (J Asthma Allergy Clin Immunol 24 : 94-102, 2004)
조덕신,이병재,민태훈,강보현,김형훈,이병완,최동철 대한내과학회 2002 대한내과학회지 Vol.63 No.4
The hemolytic uremic syndrome (HUS) is a clinical syndrome defined by the presence of thrombocytopenia, microangiopathic hemolytic anemia and acute renal failure with or without a clinically apparent etiology. The conventional treatment of choice is plasmapheresis as a first-line therapy. Most patients respond to plasmapheresis whereas some patients are refractory to the therapy. The second-line therapy is not well established although various therapies such as steroid, vincristine, intravenous immunoglobulin have been suggested. The intravenous immunoglobulin therapy in refractory hemolytic-uremic syndrome have rarely been successful in complete remission. We report a case of refractory HUS in a 48 year-old man who developed hemolytic anemia, thrombocytopenia, acute renal failure and ischemic retinopathy. The patient was refractory to plasmapheresis as a first-line therapy. The patient received intravenous immunoglobulin therapy as a second-line therapy after 8 days of plasmapheresis, which subsequently resulted in a complete remission of refractory HUS. The complete remission using immunoglobulin in HUS has not been previously reported in Korea.
조덕신,이병재,민태훈,강보현,김형훈,이병완,최동철 대한내과학회 2002 대한내과학회지 Vol.63 No.4
The hemolytic uremic syndrome (HUS) is a clinical syndrome defined by the presence of thrombocytopenia, microangiopathic hemolytic anemia and acute renal failure with or without a clinically apparent etiology. The conventional treatment of choice is plasmapheresis as a first-line therapy. Most patients respond to plasmapheresis whereas some patients are refractory to the therapy. The second-line therapy is not well established although various therapies such as steroid, vincristine, intravenous immunoglobulin have been suggested. The intravenous immunoglobulin therapy in refractory hemolytic-uremic syndrome have rarely been successful in complete remission. We report a case of refractory HUS in a 48 year-old man who developed hemolytic anemia, thrombocytopenia, acute renal failure and ischemic retinopathy. The patient was refractory to plasmapheresis as a first-line therapy. The patient received intravenous immunoglobulin therapy as a second-line therapy after 8 days of plasmapheresis, which subsequently resulted in a complete remission of refractory HUS. The complete remission using immunoglobulin in HUS has not been previously reported in Korea.(Korean J Med 63:431-435, 2002) 저자들은 국내에는 드문 성인 용혈성 요독 증후군 환자에서 혈장 교환술에 반응이 없어 이차적 치료로 면역글로불린을 투여하여 완전 치유가 되었기에 이를 문헌 고찰과 함께 보고하는 바이다.