SWAT 모형을 이용한 토지이용변화에 따른 유량 및 유사량 변화에 대한 연구

문희일 ( Hee Il Moon ),김경섭 ( Kyung Sub Kim ) 한국물환경학회 ( 구 한국수질보전학회 ) 2010 공동 추계학술발표회 Vol.2010 No.-

SWAT 모형을 이용한 토지이용 변화에 따른 유량 및 유사량 변화에 대한 연구

문희일 ( Hee-il Moon ),김경섭 ( Kyung-sub Kim ) 한국환경기술학회 2011 한국환경기술학회지 Vol.12 No.1

우리나라는 인구의 도시집중과 경제개발 계획에 따른 산업의 고도화로 토지이용이 급격히 변화하였다. 이러한 현상은 우수의 불투수지역 확대, 하천부지의 축소, 산림 및 유수지의 감소 등을 진행시켜 하천유량의 변화와 지하수위 저하 등 많은 문제점을 야기하고 있다. 따라서 토지이용 변화에 따른 하천유역의 유량을 산정하기 위해서는 과거와 현재 각각의 토지이용에 따른 유량을 산출하기 위한 수문모델을 적용하는 연구가 필요하다. 본 연구에서는 장기유출 모형인 SWAT 모델을 이용하여 유역내의 유량, 유사량을 산정하였다. 적용대상 유역은 한강수계 남한강 하류부에 위치한 흑천 유역으로 하였다. 적용 결과 유량 및 유사량은 불투수층 증가, 농업지역 감소 등 토지이용 변화에 영향을 받는 것으로 나타났다. Land use is drastically changed in recent years by urbanization, population and economic growth in Korea. It caused a lot of problems such as variation of river flow and ground water level by increase of impermeable layer and decrease of riparian land, forest and retarding reservoir etc. Therefore, it is needed to run a long-term hydrological model to estimate water quantity and quality in given watershed by the change of land use. In this research, SWAT model which is one of the long-term runoff model was utilized to simulate flow rate and sediment load. Heuk stream watershed located at downstream of south Han river was selected to know the effect of land use change. After model application, it was found that flow rate and sediment load were affected by the land use change such as impermeable layer increase and agricultural area decrease.

만성 B형 활동성 간염환자에서 HBeAg과 임상양상에 따른 간조직내 B형 간염 바이러스 Core 항원의 발현양상

문희용(Hee Yong Moon),박상진(Sang Jin Park),한광협(Kwang Hyub Han),오승희(Seung Hee Oh),전재윤(Chae Yoon Chon),문영명(Young Myoung Moon),박인서(In Suh Park),박찬일(Chan Il Park) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.4

N/A Background/Aims: The expression of hepatitis H virus core antigen(HBcAg) in the liver reflects the state of viral replication and may influence the immune response of the host. Methods: We investigated the intrahepatic expression of HBcAg using immunohistochemistry in patients with biopsy proven chronic active hepatitis B(CAH-B) according to HBeAg status and clinical patterns. Results: The intrahepatic expression of cytoplasmic HBcAg(cHBcAg) in patients with CAH-B was significantly higher in the group of HBeAg positive than negative(p0.05). In patients with HBeAg negative CAH-B, the intrahepatic expression of cHBcAg was relatively higher in the group of sustained ALT elevation during follow-up than persistent normal ALT, but statistical signifi- cance was not observed. The pattern of intrahepatic expression of cHBcAg can be different in patients with CAH-B according to the timing of the liver biopsy and the level of transaminase following the liver biopsy. Conclusions: The intrahepatic expression of cHBcAg in patients with CAH-B was different according to the timing of liver biopsy and the level of transaminase following the liver biopsy as well as HBeAg status. (Korean J Gastroenterol 1996;28: 520 - 529)

류마티스 관절염환자의 혈청 Interleukin-10

유빈 ( Bin Yoo ),박재경 ( Jae Kyoung Park ),오원일 ( Won Il Oh ),오순환 ( Sun Whan Oh ),문희범 ( Hee Bom Moon ) 대한류마티스학회 1997 대한류마티스학회지 Vol.4 No.1

Objective: To investigate whether the serum levels of IL-10 in patients with rheumatoid arthritis are different from those of normal controls and SLE patients and to find out any correlation with disease activity parameters of rheumatoid arthritis. Methods: Sera from 20 healthy normal persons, 16 rheumatoid arthritis patients and 16 patients with systemic lupus erythematosus were collected and measured for IL-10 and IL-6. Various disease activity parameters were measured in RA patients. Results: The serum level of IL-10 in RA patients was significantly elevated compared to normal controls but lower than those of SLE patients. In RA patients there was no definite correlation between the disease activity parameters and serum IL-10 levels. Despite significant improvements in terms of various disease activity parameters, there was no significant change of serum IL-10 levels after treatment in RA patients. In seropositive RA patients, positive correlation was found between serun IL-10 and rheumatoid factor levels. Conclusion: Our findings show that the serum IL-10 levels in patietns with RA are elevated compared to normal controls but lower than those of SLE patients. There was no correlation between serum IL-l0 levels and disease acivity parameters of RA.

JAUS에 따른 무인자동차 시스템 설계

문희창(Hee Chang Moon),남일진(Il Jin Nam),김정하(Jung Ha Kim) 한국자동차공학회 2005 한국자동차공학회 춘 추계 학술대회 논문집 Vol.2005 No.5_1

This paper deals with unmanned vehicle system composition and system operating test. Nowadays the research of unmanned vehicle and intelligent vehicle is increased. Especially universities and research institutes are studying unmanned vehicle system for using it to use military equipment. Generally unmanned vehicle system is compose of several system such as vehicle control system, vision system, obstacle detecting system, global positioning system, and tele-operated system. Till now, we developed each system and test it. In this paper, we explain each system of unmanned vehicle, unification method of each system and the joint reference architecture for unmanned system.

Histologic findings of three-wall intrabony defects around dental implants using different grafting materials in beagle dogs

문희일,문상권,김창성,이용근,조규성,최성호,Moon, Hee-Il,Moon, Sang-Kwon,Shim, Chang-sung,Shim, Jung-Sung,Lee, Yong-Keun,Cho, Kyu-Sung The Korean Academy of Periodontoloy 2003 Journal of Periodontal & Implant Science Vol.33 No.3

연구목적 : SLA surface dental implant 주위의 3면 골내낭에서 xenogeneic demineralized bone matric putty, porous ${\beta}$-tri-calcium phosphate, 새로이 개발된 non-crystalline calcium phosphate glass를 사용한 치료를 조직학적으로 비교 평가하기 위한 것이다. 연구방법 : 실험동물로는 15개월에서 18개월 사이의 12kg에서 15kg 정도되는 성견을 사용하였다. 20개의 SLA surface implant가 사용되었으며, 성견 하악의 양측에 각각 2개씩 사용되었다. 임플란트 식립전에, 각각의 임플란트 근심면에 straight fissure bur를 이용하여 표준화된 3면 골내앙(근원심 5mm ${\times}$협설 3mm ${\times}$깊이 3mm)을 형성하였다. 형성된 골 결손부에는 demineralized bone matrix putty, porous ${\beta}$-tri-calcium phosphate, non-crystalline calcium phosphate glass를 넣은 것을 각각 실험군으로, 이식재를 넣지 않은 것을 대조군으로 사용하였다. 8주 후에 실험 동물을 희생시키고 조직학적 관찰을 하였다. 결과 : 조직학적 소견상 임플란트 주위에 급성 염증 소견은 보이지 않았으며, non-crystalline calcium phosphate glass은 매우 적은량의 신생골을, ${\beta}$-TCP을 이용한 골내낭에서는 약간의 기저부에서 유래된 신생골이 관찰된다. ${\beta}$-TCP granules 가운데로 상당량의 측면의 골에서 유래된 신생골 형성이 보인다. xenogeneic DBM putty에서는 많은 량의 신생골이 기저부에 형성된 것을 볼수 있으나 대조군과의 차이는 크지 않다. 이식재의 종류와 상관없이 흡수되지 않은 이식재를 임플란트 주위에서 관찰할 수 있었다. 골내낭 안의 이식재들은 모두 connective tissue로 둘러 싸여 있었다. 모든 실험군에서 이식재에서 기인한 신생골 형성과 임플란트 표면에 신생 골유착의 조직학적 증거는 발견되지 않았다.

치과용 고카라트 Au-Ag-Pt-Zn 합금의 시효경화 거동

문희만(Hi-Man Moon),손국현(Kuk-Hyeon Son),박찬아(Chan-A Park),김기철(Gi-Chul Kim),박영환(Young-Hwan Park),이희경(Hee-Kyung Lee),김형일(Hyung-Il Kim) 대한치과재료학회 2002 대한치과재료학회지 Vol.29 No.3

성견 1면 골내낭에서 탈회 냉동 건조골과 calcium sulfate 혼합 이식 및 calcium sulfate 차단막 사용이 치주조직 치유에 미치는 영향

문희일,조규성,채중규,최성호,Moon, Hee-Il,Cho, Kyoo-Sung,Chai, Jung-Kiu,Choi, Seong-Ho 대한치주과학회 1998 Journal of Periodontal & Implant Science Vol.28 No.2

Numerous bone graft materials have been used in Periodontics, in an attempt to reach the main goal of periodontal therapy, i.e. the regeneration of periodontal tissue lost due to destructive periodontal diseases. The present study investigates the effect of composite graft of DFDB and Calcium sulfate with and without Calcium sulfate barrier in Periodontal 1-wall intrabony defects in dogs. Following the initiation of general anesthesia by I.V. administration of 40mg/Kg of Pentobabital, second premolar was extracted and full thickness flap elevated. The crown portion of premolars was removed. Exposed root canals were sealed with Caviton and covered completely with flap. After the healing period of 8 weeks, the surgical sites were re-opened and 1-wall intrabony defects were created, and treated with flap operation alone(control group), with composit graft of 80% DFDB and 20% Calcium sulfate(Experimental group 1), with composite graft of DFDB and calcium sulfate with calcium sulfate membrane( Experimental group 2). Healing response was histologically observed after 8 weeks and the results were as follows : 1. New bone formation was 70 % in the control group, 93 % in the Experimental group I, 89 % in the Experimental group II. There was a no differences between Experimental groups. 2. New cementum formation was not significantly different between control and two Experimental groups. 3. The length of connective tissue adhesion was 30 % in the control, 7% in the Experimental group I and 11 % in the Experimental group II. 4. After 8weeks, calcium sulfate was completely resorbed, while DFDB particle remained. These results suggest that the use of composite graft of allogenic DFDB and Calcium sulfate with and without Calcium sulfate barrier in periodontal 1 wall intrabony defects have little effect on connective tissue adhesion, but has beneficial effect on new alveolar bone and new cementum formation, and prevent downgrowth of epithelium and connective tissue effectively.

2005 DARPA Grand Challenge & Formula SAE 소개

남일진(Il Jin Nam),문희창(Hee Chang Moon),김정하(Jung Ha Kim) 한국자동차공학회 2005 한국자동차공학회 Symposium Vol.- No.-

The Defense Advanced Research Projects Agency (DARPA) intends to conduct a race of autonomous ground vehicles from the vicinity of Los Angeles, CA to Las Vegas, NV. A cash prize will be awarded to the winner. The course will feature both on-road and off-road portions and will include extremely rugged, challenging terrain and obstacles. The purpose of the race is to stimulate interest in and encourage the accelerated development of autonomous ground vehicle technologies that could be used by the US military. The other subject is Formula SAE. The Formula SAE® competition is for SAE student members to conceive, design, fabricate, and compete with small formula-style racing cars. The restrictions on the car frame and engine are limited so that the knowledge, creativity, and imagination of the students are challenged. The cars are built with a team effort over a period of about one year and are taken to the annual competition for judging and comparison with approximately 120 other vehicles from colleges and universities throughout the world. The end result is a great experience for young engineers in a meaningful engineering project as well as the opportunity of working in a dedicated team effort.

간 외 담관암의 수술과 방사선 치료의 효과

김정일 ( Jeong Il Kim ),강선형 ( Sun Hyoung Kang ),남관우 ( Gwan Woo Nam ),권대순 ( Dae Soon Kwon ),고평곤 ( Pyung Gohn Goh ),황세웅 ( Se Woong Hwang ),고광훈 ( Kwang Hun Ko ),정재훈 ( Jae Hoon Jung ),문희석 ( Hee Seok Moon ),성 대한내과학회 2008 대한내과학회지 Vol.75 No.2

목적: 간 외 담관암의 보존 요법, 근치적 수술 및 수술 후 방사선 치료의 효과를 알아보고자 하였다. 방법: 1998년부터 2005년까지 충남대학교병원에서 간 외담관암으로 치료를 받은 53명을 대상으로 하였다. 18명(1군)은 경피 경간 담도 배액술이나 내시경적 담도 배액술을 받았고, 17명(2군)은 근치적 절제술을 받았으며 18명(3군)은 근치적 절제술 후에 방사선 치료를 받았다. 결과: 1년 생존율은 1군, 2군, 3군이 각각 33.3%, 64.7%, 88.9%였고, 3년 생존율도 제 1군, 2군, 3군에서 각각 5.7%, 64.7%, 61.1%였다. 1군보다 2, 3군에서 의미있는 생존율의 향상이 있었지만 2군과 3군 사이에는 차이가 없었다. 3년 무병 생존율은 2군이 64.7%, 3군은 66.7%로 차이가 없었다. 생존율에 영향을 주는 인자로 성별, 나이, 위치, 주위 신경침범, 수술 방법, 분화도, 림프혈관 종양 색전, T 병기, N 병기를 알아보았다. 2군내에서는 수술 방법, T 병기, N 병기가 의미있는 인자였고, 3군과 비교시에 분화도가 좋을 경우에 생존율이 높았다. 3군내에서는 연령만이 의미있는 인자였고, 2군과 비교시에 림프절의 전이가 있을 경우에 생존율의 유의하게 향상되었다. 재발율은 34.3%로 주위 조직과 림프절에서 주로 재발하였으며 방사선 치료 후에 심각한 부작용은 없었다. 결론: 간 외 담관암은 비수술적인 고식적 치료보다는 근치적 절제술이 생존율 향상에 필수적이다. 또한, 근치적 절제술이 시행된 경우에 연령이 젊고 림프절의 전이가 있을 경우 방사선 치료가 생존율을 높이는데 기여하리라 사료된다. Background/Aims: To evaluate the effect and prognostic factors related to curative surgical resection and adjuvant radiotherapy in patients with extrahepatic bile duct cancer. Methods: The authors performed a retrospective analysis of 53 patients with extrahepatic bile duct cancer who were treated at Chungnam National University Hospital between 1998 and 2005. 18 patients (Group 1) were managed with percutaneous bile drainage (n=13) or endoscopic bile drainage (n=5), 17 patients (Group 2) underwent only curative resection, and 18 patients (Group 3) received radiotherapy after curative resection. The radio-sensitizer used in these patients was 5-FU. Results: Three-year overall survival was 5.6% in group 1, 64.7% in group 2, and 61.1% in group 3, with no significant difference noted between group 2 and group 3. The disease-free survival rate was 64.7% in group 2 and 66.7% in group 3, with no significant difference noted between the two groups. We evaluated age, sex, differentiation, tumor location, perineural invasion, operative method, lymphovascular tumor emboli, T stage, and N stage as possible prognostic factors. T stage, N stage, and operative method were significant factors in group 2, but age was the only significant factor in group 3. Group 2 patients had longer overall survival than did group 3 patients with well-differentiated cancer, but group 3 patients had longer survival than did group 2 patients with lymph node metastasis. The recurrence rate was 34.3% (mean value) and was no different between group 2 and group 3. Recurrence sites included local tissue, such as liver, and regional lymph nodes. There were no serious complications during radiotherapy. Conclusions: Patients who underwent curative surgical resection and adjuvant radiotherapy after surgery had no statistically significant difference in survival or recurrent rates. However, curative surgery is considered to be the only method to improve survival. Our results suggest that radiotherapy after curative resection may improve survival in patients with lymph node metastasis. (Korean J Med 75:194-201, 2008)