http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
문원진,김희진,노홍기,최진우,한설희 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.6
Objective: We hypothesized that prominent pulvinar hypointensity in brain MRI represents the disease process due to iron accumulation in Alzheimer disease (AD). We aimed to determine whether or not the pulvinar signal intensity (SI) on the fluid-attenuated inversion recovery (FLAIR) sequences at 3.0T MRI differs between AD patients and normal subjects, and also whether the pulvinar SI is correlated with the T2* map, an imaging marker for tissue iron, and a cognitive scale. Materials and Methods: Twenty one consecutive patients with AD and 21 age-matched control subjects were prospectively included in this study. The pulvinar SI was assessed on the FLAIR image. We measured the relative SI ratio of the pulvinar to the corpus callosum. The T2* values were calculated from the T2* relaxometry map. The differences between the two groups were analyzed, by using a Student t test. The correlation between the measurements was assessed by the Pearson’s correlation test. Results: As compared to the normal white matter, the FLAIR signal intensity of the pulvinar nucleus was significantly more hypointense in the AD patients than in the control subjects (p < 0.01). The pulvinar T2* was shorter in the AD patients than in the control subjects (51.5 ± 4.95 ms vs. 56.5 ± 5.49 ms, respectively, p = 0.003). The pulvinar SI ratio was strongly correlated with the pulvinar T2* (r = 0.745, p < 0.001). When controlling for age, only the pulvinar-to-CC SI ratio was positively correlated with that of the Mini-Mental State Examination (MMSE) score (r = 0.303, p < 0.050). Conversely, the pulvinar T2* was not correlated with the MMSE score (r = 0.277, p = 0.080). Conclusion: The FLAIR hypointensity of the pulvinar nucleus represents an abnormal iron accumulation in AD and may be used as an adjunctive finding for evaluating AD.
냉각제어된 Fe-Si-Mn-P 고장력 강판의 미세조직 및 기계적성질
문원진,김익수,강창용,성장현,김기도 ( Won Jin Moon,Ik Su Kim,Chang yong Kang,Jang Hyun Sung ) 한국열처리공학회 1997 熱處理工學會誌 Vol.10 No.2
Microstructure and mechanical properties of Fe-Si-Mn-P high strength steel sheet have been investigated by controlling the cooling rate. Bainite and ferrite were obtatined by annealing in the ferrite pluse austenite region, and ferrite and austenite were obtatined after annealing in the fully austenite region. Ferrite and pearlite were obtained when the cooling rate was controlled from the annealing temperature above 760℃ and bainite showed with increasing cooling rate, however below 760℃ ferrite and bainite were obtained. Tensile strengths and hardness nearly unchanged with increasing cooling rate after control the cooling rate from the temperature above 760℃, while tensile strengths increased and elongation decreased with increasing cooling rate when the cooling rate was controlled from the tempeature below 760℃. Without regard to annealing temperature, tensile strength increased and elongation decreased with increasing cooling rate. Tensile strengths and elongation values heat treated in the ferrite plus austenite region were higher than those in the fully austenite region. Retained austenite and strength-elongation balance showed the maximum value at 780℃ and decreased with increasing annealing temperature. Strength-elongation balance value was controlled by the retained austenite.
Fe-Si-Mn-P강판의 초기조직변화가 잔류오스테나이트 형성 및 인장성질에 미치는 영향
문원진,강창용,김한군,김기돈,성장현 ( Won Jin Moon,Chang Yong Kang,Han Goon Kim,Ki Don Kim,Jang Hyun Sung ) 한국열처리공학회 1997 熱處理工學會誌 Vol.10 No.1
This study has been conducted to investigate the effects of initial structure on the microstructure and tensile properties of high strength trip steel sheet. The initial structure before austempering remarkably influenced the second phase. The specimen with normalized initial structure showed mainly bainitic ferrite and retained austenite, while the as rolled specimen and spherodized specimen showed martensite plus retained austenite and martensite plus bainitic ferrite with small retained austenite, respectively. Two type of retained austenite, film type and granual type were observed in all specimens. The as rolled specimen appeared the highest contents of retained austenite owing to the compressive stress by cold rolling. The contents of retained austenite increased with increasing intercritical annealing temperature and austempering time. Tensile strength showed the highest in the as rolled specimen, while the highest elongation were obtained in the normalized specimen. The maximum T.S.×El. Value showed in normalized initial structure and increased with increasing intercritical annealing and austempering time. The highest Value of T.S.×El. obtained at austempering temperature of 400℃ and retained austenite of 12%.
문원진,백정환,정소령,김동욱,김은경,김지영,곽진영,이정현,이준형,이영흔,나동규,박정선,박선원 대한영상의학회 2011 Korean Journal of Radiology Vol.12 No.1
The detection of thyroid nodules has become more common with the widespread use of ultrasonography (US). US is the mainstay for detecting and making the differential diagnosis of thyroid nodules as well as for providing guidance for a biopsy. The Task Force on Thyroid Nodules of the Korean Society of Thyroid Radiology has developed recommendations for the US diagnosis and US-based management of thyroid nodules. The review and recommendations in this report have been based on a comprehensive analysis of the current literature, the results of multicenter studies and from the consensus of experts.
문원진,박동우,이승로,성진용,송순영,함창곡,김용수,박충기,태경,Moon, Won-Jin,Park, Dong-Woo,Lee, Seung-Ro,Seong, Jin-Yong,Song, Soon-Young,Hahm, Chang-Kok,Kim, Yong-Soo,Park, Choong-Ki,Tae, Kyung 대한영상의학회 1998 대한영상의학회지 Vol.38 No.2
Purpose: Tympanosclerosis is a common problem causing conductive hearing loss accompanied by chronic otitismedia. The purpose of this study was to evaluate the CT findings of tympanosclerosis, and correlate them with thesurgical findings. Materials and Methods: The CT scans of 17 patients with surgically-proven tympanosclerosis andthose of a control group of 34 patients with nontympanosclerotic chronic otitis media were reviewed. According totheir location, they were assigned to one of three groups; tympanic membrane, epitympanum, or ossicles. Results:Tympanosclerosis was found during surgery to be located in the tympanic membrane (n=11), the epitympanum (n=6), oraround the ossicles(n=8). Calcification of the tympanic membrane, ossicular thickening, narrowing of theepitympanum and calcification of the tympanic cavity occurred to a significant extent, and were more often afeature of tympanosclerosis than of nontympanosclerotic chronic otitis media (p<0.05). As an indicater of tympanicmembrane involvement, sensitivity and specificity of calcification of the tympanic membrane were 73% and 83%,respectively. As an indicator of ossicular involvement, the corresponding figures for ossicular thickening were50% and 93% ; as an indicator of involvement of the tympanic cavity (especially the epitympanum) the figures fornarrowing of the epitympanum and calcification of the tympanic cavity were 50% and 50% (respective sensitivities),and 89% and 93%(respective specificities). Conclusion: Tympanosclerosis usually appears on CT as ossicularthickening, narrowing of the epitympanum, calcification of the tympanic membrane and/or tympanic cavity. CT isvery helpful in evaluating ossicular involvement and determining the appropriate surgical treatment oftympanosclerosis.
문원진 대한영상의학회 1997 대한영상의학회지 Vol.37 No.5
Purpose : To compare the precise roles of high-resolution computed tomography (HRCT) and fiberopticbronchoscopy (FOB) in the evaluation of patients presenting with hemoptysis and to determine the optimal timingfor HRCT. Materials and Methods : The results of HRCT and FOB were compared in 23 patients (15 men, 8 women)presenting with hemoptysis. Etiologies included bronchietasis(n=4), parenchymal pulmonary tuberculosis(n=4), lungcancer(n=4), endobronchial tuberculosis(n=2), and broncholithiasis(n=2). Hemoptysis was proved to be due tomiscellaneous causes in an additional three cases and to be cryptogenic in four. The diagnostic results of FOBperformed before and after HRCT were compared as were those of HRCT performed within and after the first 48 hoursof active bleeding. Results : FOB and HRCT offered a correct diagnosis in 39% and 65% of cases, respectively(p=0.005). HRCT demonstrated three cases of bronchiectasis and three of parenchymal pulmonarytuberculosis which were beyond the range of a bronchoscope. In two of five cases in which HRCT findings werenonspecific, chondromatous hamartoma and lung cancer were confirmed by FOB. In cases where HRCT was performedprior to FOB, the latter demonstrated the location and diagnosis in 82% and 47% of cases, respectively (p=0.303) ;when HRCT was performed after FOB, HRCT was correct in 67% and 17% of cases, respectively (p=0.178). In none ofthree cases (0%) in which HRCT was performed during the first 48 hours of active bleeding did the procedure allowa specific diagnosis. In 15 of 20 (75%) cases in which HRCT was performed after the first 48 hours, however, thediagnosis provided by CT was correct. Conclusions : The results of this study suggest that in patients presentingwith hemoptysis, both HRCT and FOB should be used for evaluation, since they are diagnostically complementary. FOBis more useful for the diagnosis of endobronchial lesion, and HRCT for bronchiectasis and parenchymal pulmonarytuberculosis. If, in cases of hemoptysis, initial diagnosis is attempted within the first 48 hours of activebleeding, FOB should be the initial step, and HRCT images should not be obtained until active bleeding has beenshown on plain chest radiograph to have abated. If this initial approach takes place after the first 48 hours ofactive bleeding, FOB and HRCT are equally suitable.
신경계를 침범한 Langerhans 조직구 증식증 : 1예 보고
문원진 대한영상의학회 1997 대한영상의학회지 Vol.36 No.1
Langerhans 조직구 증식증은 세망내피계에 조직구의 특발성 증식을 특징으로 하는 전신 질환으로 신경계 이환은 시상하부와 뇌하수체후엽 침범이 가장 흔하며, 그 외 부위의 침범은 매우 드문 것으로 알려져 있다. 저자들은 시상하부와 함께 뇌간, 소뇌 및 측두엽을 침범한 Langerhanms 조직구 증식증 1예를 보고하고자 한다. 이 병변은 MRI상 T1강조영상 에서 동등 혹은 저신호 강도, T2강조영상에서 고신호강도을 나타내었고, CT 상 동등 밀도 의 종괴로 보였으며, CT 및 MRI 조영증강 영상에서 조영증강되는 다발성 결절로 관찰되었 다. Langerhans cell histiocytosis(LCH) is a systemic disorder characterized by idiopathic proliferation of histiocytes in the reticuloendothelial system; CNS involvement outside the hypothalamus or pituitary gland is uncommon. We present a case of LCH involving the brainstem, cerebellum, and temporal lobes, and also showing hypothalamic involvement. The lesions were isointense or hypointense on T1WI and hyperintense on T2WI, and showed multifocal enhancing nodules on post-contrast CT and Gd-enhanced MRI.
문원진,박주연,Won-Sung Yun,전지영,문연실,Heejin Kim,곽기창,Jong-Min Lee,한설희 대한영상의학회 2016 Korean Journal of Radiology Vol.17 No.5
Objective: Neuromelanin loss of substantia nigra (SN) can be visualized as a T1 signal reduction on T1-weighted highresolution imaging. We investigated whether volumetric analysis of T1 hyperintensity for SN could be used to differentiate between Parkinson’s disease dementia (PDD), Alzheimer’s disease (AD) and age-matched controls. Materials and Methods: This retrospective study enrolled 10 patients with PDD, 18 patients with AD, and 13 age-matched healthy elderly controls. MR imaging was performed at 3 tesla. To measure the T1 hyperintense area of SN, we obtained an axial thin section high-resolution T1-weighted fast spin echo sequence. The volumes of interest for the T1 hyperintense SN were drawn onto heavily T1-weighted FSE sequences through midbrain level, using the MIPAV software. The measurement differences were tested using the Kruskal-Wallis test followed by a post hoc comparison. Results: A comparison of the three groups showed significant differences in terms of volume of T1 hyperintensity (p < 0.001, Bonferroni corrected). The volume of T1 hyperintensity was significantly lower in PDD than in AD and normal controls (p < 0.005, Bonferroni corrected). However, the volume of T1 hyperintensity was not different between AD and normal controls (p = 0.136, Bonferroni corrected). Conclusion: The volumetric measurement of the T1 hyperintensity of SN can be an imaging marker for evaluating neuromelanin loss in neurodegenerative diseases and a differential in PDD and AD cases.