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      • SCOPUSKCI등재

        대동맥류의 수술적 치료에 관한 임상적 연구

        류지윤,전홍주,조광현,Ryu, Ji-Yun,Jeon, Hong-Ju,Jo, Gwang-Hyeon 대한흉부심장혈관외과학회 1997 Journal of Chest Surgery (J Chest Surg) Vol.30 No.3

        We have experienced 25 cases of aortic aneurysm from October 1987 to January 1996. Patients ranged in age from 26yrs to 73yrs(mean age 52. Syrs). There were 13 males and 12 females. Eighteen cases were thoracic aneurysm and seven were abdom nal aneurysm. The cause of aneurysm were dissecting in 16cases aneurysms and non-dissecting in 9 cases. Risk factors of aortic aneurysm were hypertension, hypercholesterolemia, Marfan's syndrome. In thoracic aneurysm patients, 1'S cases of dissecting aneurysm underwent aneurysmectomy and replacement of vessel interposition graft with or without coronary artery implantation on the graft. 6 cases of non-dissecting aneurysm underwent operation with same policy as dissecting aneurysm. In 7 case of abdominal aneurysm,all patients underwent aneurysmectomy and graft interposition with straight i)r Y graft. Thcre were 5 postoperative death(mortality 20%). Several cases of complications were improved with proper managements. All survivors showed improvement in clinical symptom and sign and discharged without specific complications. 인제대학교 부속 부산백병 원 흉부외과학교실에서는 지난 87년 10월부터 96년 1월까지 총25례의 흉부 및 복부 대동맥류를 수술로 치험하였다. 환자의 연령은 최소 26세에서 최고 73세(평균연령 52. 5세)였으며 남자가 13명 여자가 12명이였다. 발생 부위에 따라흉부 대동맥류가 18례 복부 대동맥류가7례였다. 원인에 따른 분류에서 16례가 박리성이 였으며 9례가 비박리성 대동맥류였다. 동맥류의 위험 인자로는 고혈압이 가장 많았으며 기타 고지질증, Marfan증후군등이였다. 흉부 대동맥류는 침범 부위에 따라 동맥류 절제술과 인조혈관 대치술 및 관상동맥 이식술등을 증례에 따라적절히 시행하였다. 복부 대동맥류는 동맥류 절제후 침범 부위에 따라 일자 또는 역Y형 인조혈관 을 대 치시켰다. 총 5례의 술후 사망이 있어서 수술 사망률은 20%였으며 생존 환자는 특별한 합병증 없이 퇴원하였다.

      • SCOPUSKCI등재

        심내막상 결손증 술후 추적 관찰에 관한 연구

        류지윤 대한흉부심장혈관외과학회 1994 Journal of Chest Surgery (J Chest Surg) Vol.27 No.3

        Endocardial cushion defect is a rare congenital heart disease. From September 1985, we experienced 20 cases of endocardial cushion defects and postoperative follow up was taken.We reviewed preoperative clinical data, echocardiography, cardiac cath data, operative method & time. After operation, we performed echocardiography and examined mitral valve function & integrity of patch closure sites. Postoperative follow up was taken regularly & follow up period was from 2 month to 91 months. Several postoperative complications were overcome with adequate treatment. There were 3 cases of early death and mortality rate was 15% [3/20].

      • 六味地黃湯 및 八味地黃湯이 抗改良型 馬杉腎炎에 미치는 影響

        柳志允 圓光大學校大學院 1983 學位論叢 Vol.10 No.-

        The curative effectiveness of Yukmijiwhangtang and Palmijiwhangtand for kidney disease has been widely known in oriental medicine. Their effectiveness in clinical therapy was investigated in this paper. This study was to investigate the anti-nephritic effects of the treatments of Yukmijiwhangtang and Palmijiwhangtang on the modified Masugi's nephritis. With the modified model of Masugi's nephritis in rat, the antinephritic effects of Yukmijiwhangtang and Palmijiwhangtang were evaluated by determing the biochemical parameters in urine, serum and renal cortex as well as by light microscopic observation in kidneys. After manafacturing the anti-rat kidney serum, it was given to the subjects in order to bring about nephritics. The results of this study were as follows: 1. The level of protein in urine was reduced significantly on 30th day after treatment of Yukmijiwhangtang. 2. THe level of protein in urine was reduced significantly on 10th day after treatment of Palmijiwhangtang. 3. The activity levels of AIP and LDH were reduced but not significant. 4. The levels of choresterol and triglyceride in serum of nephritic rats with the treatment of Palmijiwhangtang were reduced significantly on 30th day after treatment. The level of BUN was not significant. 5. Histological examination using a light microscope showed a significant recovery of glomerular lesions of nephritic rats treated with Palmijiwhangtang.

      • 開心術 時 血淸 β₂-microglobulin의 變動에 關한 硏究

        柳智允 인제대학교 1989 仁濟醫學 Vol.10 No.2

        오늘날 개심수술의 성적은 현저히 진보되었다고 할 수 있는 반면, 개심술 후 신장기능 부전증의 발생률은 심장수술 대상자의 확대와 어려운 장시간의 수술 등으로 인하여 오히려 증가된 상태에 있다고 하겠다. 신부전이란 일단 발생하게 되면 환자의 예후를 크게 좌우하기 때문에 신부전의 조기 진단과 치료는 환자의 예후에 매우 중요하다. Berggard가 밝힌 저분자 단백인 β2-MG(분자량 11,800)가 최근 신 기능의 지표로써 응용되고 있는데, 혈중 β2-MG는 쉽게 신 사구체 기저막을 통과하여 세뇨관에서 거의 모두 재흡수되어 세뇨관상피에서 대사 분리된다. 따라서 사구체 기능 장해가 있으면 혈중 β2-MG의 농도가 증가될 것이며, 재흡수 장해가 있으면 뇨중 β2-MG의 배설량이 증가된다는 사실에 바탕을 두고 있다. 개심술에 의한 신 기능의 변화를 예상하는데 도움이 되는지의 여부를 검토하기 위하여 저자는 소아 및 성인 개심술 환자 55명에서 혈중 β2-MG치의 수술 전후 변동을 추적하여 다음과 같은 결과를 얻었다. 1.開心術 全例에서 수술 후 제 1일째부터 혈청β2-MG치의 상승이 있었다. 2.수술 전 BUN치와 β2-MG치의 상관관계를 검토해본 결과 소아군(N=25)에서는 상관계수(r)가 0.8512, 성인군(N=30)에서는 상관계수(r)가 0.8636으로 양군 모두 매우 유의한(p<0.001) 正常關 관계를 보여주었다. 3.소아군과 성인군 모두 술후 4일째 β2-MG치는 각기 2.61±0.88mg/l, 3.39±1.47mg/l로 최대치에 도달하려는데, 양군간에 의미있는 차(p<0.05)가 있었고, 술후 7일째 양군 모두 술전치에 접근하였다. 4.소아 및 성인 양군 모두에서 BUN치의 시간적 변동과 β2-MG치의 시간적 변동이 유사한 변화를 하였으나 신 기능 부전으로 사망한 1례에서는 β2-MG치의 변동이 보다 예민하였다. 5.체외순환 60분 미만군(N=24)과 60분 이상군(N=31) 상호간에 술후 β2-MG 최대치에 유의한 차(p<0.01)가 있었다. Nowadays, inspite of the remarkable development of the results of open heart surgery, the incidence of postoperative acute renal failure (ARF) has been increased due to the expansion of the candidates and prolonged operation time for complicated cases. It is also well known that ARF after open heart surgery, if once occurred, is a critical complication, therefore early diagnosis and treatment about it are very important for prognosis. Recently a low molecular weight β2-microglobulin (β2-MG) has been used as a indicator of renal function. Because of the properties of β2-MG, serum concentration of it is increased in glomerular dysfunction and urine excretion of it is increased in tubular dysfunction. Author studied about the perioperative changes of serum β2-MG and BUN concentration in 25 children and 30 adults for evaluation of the significances of β2-MG as a parameter of postoperative renal function in open heart surgery, and the results were obtained as follows. 1.In open heart surgery the serum β2-MG concentration was elevated postoperatively in the all cases from the first postoperative day. 2.There were a significant correlation between the preoperative BUN and β2-MG concentration (p< 0.01). The correlation factor (r) in child group was 0.8512, and in adults 0.8636, 3.The maximum level of serum β2-MG in the both child and adult groups were noticed in 4th. postoperative day as 2.61 ±0.80 mg/l in child group and 3.39±1.47 mg/l in adult group, and there was a significant difference between the two groups statistically (p<0.05). 4.The pattern of changes of serum concentration of β2-MG with time was very similar with the changes of BUN, but in a case of ARF (expired with it) the changes of β2-MG was more remarkable. 5.There was a significant differences in the maximum level of β2-MG between the 2 groups according to the ECC time (groups of below and above 60 minutes) (p<0.01).

      • SCOPUSKCI등재

        식도의 평활근종 수술치험 1

        류지윤,우종수,조광현,Ryu, Ji-Yun,U, Jong-Su,Jo, Gwang-Hyeon 대한흉부심장혈관외과학회 1987 Journal of Chest Surgery (J Chest Surg) Vol.20 No.1

        We experienced a case of esophageal leiomyoma recently in department of Thoracic and Cardiovascular Surg., Pusan Baik Hospital, Inje Medical College. Patient had suffered from dysphagia and chest discomfort for 2 years. The esophagogram showed an ovoid smooth filling defect in lower portion of the esophagus, mucosal fold of esophagus was not destroyed. A benign intramural tumor of the esophagus such as leiomyoma was suspected with X-ray finding and clinical features. Open thoracotomy was performed through the left 8th intercostal space. A firm egg sized mass in the well of lower esophagus was enucleated by blunt dissection with caution to avoid injury of the mucosa of the esophagus. The diagnosis of leiomyoma was confirmed with histopathological finding. Postoperative course was uneventful.

      • KCI등재

        Clinical Analysis of Spontaneous Pneumomediastinum

        류지윤 대한결핵및호흡기학회 2012 Tuberculosis and Respiratory Diseases Vol.73 No.3

        Background: Spontaneous pneumomediastinum is a rare and benign condition that generally occurs in young generations without any precipitating factor or underlying disease. The purpose of this study is to review our experience in dealing with this entity and detail a reasonable course of assessment and management. Methods: From December 1999 to May 2012, 32 spontaneous pneumomediastinum patients were managed in our hospital. We retrospectively reviewed the result of management. Results: Patients ranged in age from 10 to 38 years, with the mean age of 18.3±5.6 years. Twenty-five patients were men and seven were women. Initial WBC count was 10,039±2,993/μL and thirty-one patients underwent computed tomography. Twenty-two patients underwent esophagography and results were shown to be normal. Twenty-five patients were admitted in the hospital and the mean duration of admission was 3.4±2.0 days. All patients were managed conservatively and discharged without any complications. Conclusion: Spontaneous pneumomediastinum is a benign condition combined with mild inflammatory signs and secondary causes must to excluded to avoid unfavorable outcomes and select proper management modality. Background: Spontaneous pneumomediastinum is a rare and benign condition that generally occurs in young generations without any precipitating factor or underlying disease. The purpose of this study is to review our experience in dealing with this entity and detail a reasonable course of assessment and management. Methods: From December 1999 to May 2012, 32 spontaneous pneumomediastinum patients were managed in our hospital. We retrospectively reviewed the result of management. Results: Patients ranged in age from 10 to 38 years, with the mean age of 18.3±5.6 years. Twenty-five patients were men and seven were women. Initial WBC count was 10,039±2,993/μL and thirty-one patients underwent computed tomography. Twenty-two patients underwent esophagography and results were shown to be normal. Twenty-five patients were admitted in the hospital and the mean duration of admission was 3.4±2.0 days. All patients were managed conservatively and discharged without any complications. Conclusion: Spontaneous pneumomediastinum is a benign condition combined with mild inflammatory signs and secondary causes must to excluded to avoid unfavorable outcomes and select proper management modality.

      • SCOPUSKCI등재

        형질세포 육아종 1례 치험 보고

        류지윤,우종수,조광현,Ryu, Ji-Yun,U, Jong-Su,Jo, Gwang-Hyeon 대한흉부심장혈관외과학회 1987 Journal of Chest Surgery (J Chest Surg) Vol.20 No.4

        Plasma cell granuloma of the lung is very rare and most commonly detected in routine chest films. The prognosis of this disease is usually good with surgical resection. Recently, we experienced a case of this, the diagnosis of which was confirmed by postoperative histopathological examination. The operation was right upper lobectomy under the impression of benign tumor of the lung. The postoperative course was uneventful and the patients was discharged without any complication. Now we report this with literature reviews.

      • 상지 동맥 폐쇄를 동반한 흉곽출구증후군 수술 치험 : a case report

        류지윤,김연수,장우익,김욱성 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.2

        Thoracic outlet syndrome refers to the compression of the subclavian vessels and brachial plexus at the superior aperture of the thorax. It was previously designated according to the presumable etiologies such as scalenus anticus, costoclavicular, hyperabduction, cervical rib, and first thoracic rib syndromes. We experienced a case of thoracic outlet syndrome(cervical rib) combined with arterial obstruction of upper extremity. A 47-year-old male patient had suffered from pain, tingling sensation, and coldness of right hand. Preoperative brachial and CT angiography showed extrinsic compression of proximal subclavian artery with luminal thrombosis. Thromboendarterectomy and division of pectoralis minor tendon were done(1st operation), Transaxillary resection of first rib, cervical rib and scalenus anticus, thoracoscopic thoracic sympathicotomy and thromboendarterctomy were done(2nd operation). Thromboembolectomy was done(3rd operation). After the final operation good arterial pulsation of upper extremity was shown and maintained.

      • SCOPUSKCI등재

        흉곽출구 증후군 수술 치험 1례

        류지윤,강인득,조광현,Ryu, Ji-Yun,Gang, In-Deuk,Jo, Gwang-Hyeon 대한흉부심장혈관외과학회 1988 Journal of Chest Surgery (J Chest Surg) Vol.21 No.3

        Thoracic outlet syndrome refers to compression of the subclavian vessels and brachial plexus at the superior aperture of the thorax. it was previously designated according to presumable etiologies such as scalenus anticus, costoclavicular, hyperabduction, cervical rib and first thoracic rib syndromes. We experienced a case of thoracic outlet syndrome[costoclavicular syndrome] which was caused by posttraumatic left clavicular fracture. Patient had suffered from swelling and cyanosis of left forearm and hand. preoperative vascular doppler test, angiography and venography were performed. First rib resection was done with transaxillary approach. After operation preoperative cyanosis and swelling of left forearm and hand were disappeared. Postoperative course was uneventful.

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