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Idiopathic Pleuroparenchymal Fibroelastosis Presenting in Recurrent Pneumothorax: A Case Report
노현진,송정섭,서윤,허솔미,김태정,김효림 대한결핵및호흡기학회 2014 Tuberculosis and Respiratory Diseases Vol.77 No.4
Idiopathic pleuroparenchymal fibroelastosis (PPFE) is a rare, recently classified entity that consists of pleural and subjacent parenchymal fibrosis predominantly in the upper lungs. In an official American Thoracic Society/European Respiratory Society statement in 2013, this disease is introduced as a group of rare idiopathic interstitial pneumonias. We describe a case of a 76-year-old woman with cough and recurrent pneumothorax. She was admitted to our hospital with severe cough at first. High resolution computed tomography (HRCT) disclosed multifocal subpleural consolidations with reticular opacities in both lungs, primarily in the upper lobes, suggesting interstitial pneumonia. Rheumatoid lung was diagnosed initially through an elevated rheumatoid factor, HRCT and surgical biopsy at the right lower lobe. However, one month later, pneumothorax recurred. Surgical biopsy was performed at the right upper lobe at this time. The specimens revealed typical subpleural fibroelastosis. We report this as a first case of idiopathic PPFE in Korea after reviewing the symptoms, imaging and pathologic findings.
The Relationship between Hippocampal Volume and Cognition in Patients with Chronic Primary Insomnia
노현진,주은연,김성태,윤소미,구대림,김대영,이근호,홍승봉 대한신경과학회 2012 Journal of Clinical Neurology Vol.8 No.2
Background and Purpose Differences in hippocampal volume (HV) were compared between chronic primary insomniacs (PIs) and good sleepers (GSs), and the relationship between HV and memory function in PIs was investigated to clarify the effect of chronic sleep deprivation on brain structure and cognition. Methods Twenty PIs (mean age, 50 years; 18 females) and 20 age-, gender-, and educationmatched GSs were enrolled. Brain magnetic resonance imaging (MRI) was performed on a 1.5-T MRI scanner. Left and right HV and intracranial volume (ICV) were measured manually. Nighttime polysomnography and neuropsychological testing were also applied to all subjects. Group differences in HV were analyzed and the relationships between HV and sleep questionnaire data, nighttime polysomnography, and neuropsychological findings were evaluated. Results Compared to GSs, PIs exhibited significantly increased sleep latency and arousal index and a decreased percentage of REM sleep in nighttime polysomnography, as well as impaired verbal and visual memory, and frontal lobe function. Absolute HV and ICV did not differ significantly between PIs and GSs. In the PIs, right and left HVs were negatively correlated with the duration of insomnia and the arousal index, and positively correlated with the recognition of visual memory. In addition, free recall in verbal memory was positively correlated with left HV in PIs. Conclusions These findings suggest that chronic sleep deprivation impairs memory and frontal lobe function, and that a long duration of insomnia and poor sleep quality contribute to a bilateral reduction in HV.
노인주거시설의 공용공간 변화에 관한 연구 : 1960년대와 1990년대의 미국 사례를 중심으로 Focused on the 1960s and 1990s in the U.S
노현진,김혜정 대한건축학회 2000 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.20 No.1
The purpose of this study is to analyze the change of communal spaces in the elderly housing in the U.S. between the 1960s and 1990s, in order to propose a new direction of communal spaces for the elderly housing in Korea. The research method which has been used is a case study. Ten cases which have been built in 1960s and 7 cases which have been built in 1990s are analyzed. focused on the spaces for the basic public life, leisure, activities and convenience. The research findings are as follows : 1) There is tendency that the communal space has become subdivided from a lager and center oriented, to small various place within the community. 2) In terms of basic public spaces, the type of- facilities are same as in the 1960, yet small, various type has been provided in the case of the 1990s 3) Outdoor leisure spaces and religious service facilities has been reduced in terms of, sizes and facility types. 4) The medical care facilities and everyday life-support facilities such as bank and commercial facilities are increased.
노현진,최진욱,김준표,문경준,방오영 대한신경과학회 2014 Journal of Clinical Neurology Vol.10 No.3
Background Primary angiitis of the central nervous system (PACNS) is a rare disorder and isoften difficult to diagnose due to the lack of a confirmatory test. PACNS can generally be diagnosed based on typical angiographic findings. We describe herein a patient diagnosed with PACNSdespite the presence of normal findings on conventional angiography. Case Report A 44-year-old man with a recent history of ischemic stroke in the right posteriorcerebral artery territory developed acute-onset vertigo. Diffusion-weighted imaging revealed anacute infarction within the left posterior inferior cerebellar artery. His medical history was unremarkable except for hyperlipidemia; the initial examination revealed mild gait imbalance. Duringthe 10 days of hospital admission, the patient experienced four recurrent ischemic strokes withinthe posterior circulation territory (occipital lobe, pons, and cerebellum). He was diagnosed withrecurrent cerebral infarctions due to PACNS. The basilar artery exhibited no demonstrable luminal stenosis, but there were direct imaging signs of central nervous system angiitis including wallthickening and contrast enhancement. High-dose intravenous steroid therapy followed by oralprednisolone was administered. There was no further stroke recurrence and follow-up imagingof the arterial walls showed normalization of their characteristics. Conclusions The present case emphasizes the importance of wall imaging in the diagnosis andtreatment of PACNS.