한국인에서 안면 주름과 양성교근비대증에서의 A형 보툴리눔 독소 치료

노낙경 ( Nark Kyoung Rho ),김혜성 ( Hai Sung Kim ),김윤성 ( Yoon Seong Kim ),김연진 ( Yun Jin Kim ),김종혁 ( Chong Hyeok Kim ),민복기 ( Pok Kee Min ),서석배 ( Suk Bae Suh ),이강석 ( Kang Seok Lee ),이상주 ( Sang Ju Lee ),이우선 ( 대한피부과학회 2010 대한피부과학회지 Vol.48 No.10

Background: The utilization of botulinum toxin has rapidly expanded into various aesthetic applications. Achieving success with the aesthetic use of neurotoxins depends on several factors, including an understanding of the anatomy, the methods of dilution and the injection technique. Any guidelines representing a consensus for aesthetic treatments using botulinum toxin type A (BTA) have not been published in Korea. Objective: We wanted to provide consensus recommendations on the treatment of facial wrinkles and benign masseter hypertrophy using BTA in Korean patients. Methods: A panel of experienced Korean dermatologists was convened to develop a clinical consensus. The clinical consensus was comprised of the recommendations of the panel and the guidelines on general issues, such as the reconstitution and handling of the BTA, the procedural considerations, the dosing and injection-site standardizations, and the prevention and treatment of unwanted effects. Specific recommendations were provided according to the area of treatment, including glabellar lines, horizontal forehead lines, lateral periorbital wrinkles and benign masseter hypertrophy. Results: The recommended final concentration of BTA was 50 units/ml (5 units/0.1 ml) after reconstitution with physiologic saline. For glabellar lines, the members recommend three injection points (a total of 8 units). For forehead wrinkles, the members recommend nine injections in two rows into the frontalis with 1 unit/point. For crow`s feet, the members recommend three injections per side (7 units/side) at the lateral part of the orbicularis oculi. For benign masseter hypertrophy, three injections per side (24~30 units/side) were recommended. Conclusion: These consensus recommendations will provide a framework for Korean dermatologists who wish to perform safe and efficacious injection of BTA for facial rejuvenation. (Korean J Dermatol 2010;48(10):823~831)

Filler injection techniques for nasolabial folds and periorbital lines

노낙경 ( Nark Kyoung Rho ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2

군인에서 발생한 동창의 임상적 고찰

노낙경 ( Nark Kyoung Rho ),권용현 ( Yong Hyun Kwon ),이가영 ( Ga Young Lee ),김원석 ( Won Serk Kim ),김계정 ( Kea Jeung Kim ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.10

Background: Chilblain or pernio is a cold-induced, inflammatory skin problem which occurs usually on acral areas bilaterally. Because chilblain commonly develops in cold, damp climates, many soldiers may experience occupational chilblain during military service in Korea. Objective: The purpose of this study is to analyze the clinical characteristics of chilblain in Korean soldiers. Methods: We reviewed the clinical findings in 199 patients with chilblain who visited the department of dermatology, Armed Forces Capital Hospital during the 5-year period from 2002 to 2007. We investigated the epidemiology, aggravation factors, duration of the disease, clinical manifestations and treatment. Results: The results were as follows; The average age was 21.51±1.86 years old. The chilblain usually developed during winter and the duration of symptoms ranged from 1 day to 4 years. All patients developed skin lesions on acral areas. Erythematous skin lesions were observed in 133 patients and purpuric lesions were seen in 56 patients. The lesions were symmetrical in 171 patients 43 patients had history of recurrence. Treatment includes nifedipine and pentoxyfilline. The supportive treatment includes rest and keeping warm, topical corticosteroids or antibiotics and oral antihistamine, analgesics, or antibiotics. Conclusion: This investigation is expected to help understand and obtain more information on chilblain. (Korean J Dermatol 2007;45(10):996∼1003)

피부 병변과 무균성 뇌수막염을 동반한 Kikuchi 병 ( Histiocytic Necrotizing Lymphadenitis ) 1 예

노낙경(Nark Kyoung Rho),최석진(Suk Jin Choi),정찬우(Chan Woo Jeong),이일수(Eil Soo Lee) 대한피부과학회 2001 대한피부과학회지 Vol.39 No.8

Histiocytic necrotizing lymphadenitis, or Kikuchi’s disease, is a benign self-limiting febrile illness usually affecting young women, which is manifested clinically by fever and cervical lymphadenopathy. Skin involvement in Kikuchi’s disease is not frequent and Kikushi`s disease presenting as aseptic meningitis is rare, with only three previous reports in English literature to date. We present a 16-year-old girl with cervical lymphadenopathy and fever who was diagnosed with Kikuchi’s disease, suffering from multiple transient erythematous maculopapular skin lesions and presenting as aseptic meningitis. (Korean J Dermatol 2001;39(8): 896-901)

I am ready to inject botulinum toxin

노낙경 ( Nark Kyoung Rho ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2

Aesthetic use of botulinum toxin is very popular all over the world. From simple correction of the wrinkle to change the shape of the face, botulinum toxin injection is one of the basic procedures in daily dermatologic practice. But, still the lack of training opportunities makes residents and young dermatologists afraid of using it freely. Now, The Korean Society for Dermatologic Surgery, with the help of the Korean Dermatologic Association, has a plan to have bi-annual hands-on workshop for botulinum toxin treatment to improve skills and the latest knowledge of botulinum toxin for residents and young dermatologist. This course is an introduction in the use of botulinum toxin in facial aesthetics. It is ideal for the complete beginner, but also serves as a course for delegates that have attended courses elsewhere and wish to re-establish a sound foundation in this most important discipline and treatment modality. A great emphasis is placed on mastering the basic, standard techniques for the most-commonly treated facial indications, including horizontal forehead lines, glabellar frown wrinkles, periorbital wrinkles, and masseter hypertrophy. Aims and objectives: To gain an understanding of the history of Botulinum Toxin Where Botulinum Toxin is commonly used The use of Botulinum Toxin in aesthetic medicine Pharmacology and Toxicology Anatomical considerations (with special emphasis on the ethnic differences) Dosage Preparation & injection Techniques To gain and understand the importance of accurate patient assessment from the initial consultation through to the actual treatment itself by watching live demonstrations To understand how to carry out the procedures by undertaking a practical workshop in botulinum toxin (hands on workshop session) Program director Chang-Hun Huh, MD, PhD (Department of Dermatology, Seoul National University College of Medicine)

광범위 항생제 장기 사용 후 발생한 그람 음성 모낭염

김민구 ( Min Gu Kim ),노낙경 ( Nark Kyoung Rho ) 대한피부과학회 2006 대한피부과학회지 Vol.44 No.3

총상 신경초종 2 예

오정준(Jeong Joon Oh),노낙경(Nark Kyoung Rho),박상진(Sang Jin Park),이일수(Eil Soo Lee) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.8

We present two cases of plexiform schwannoma, a benign peripheral nerve sheath tumor, characterized by a plexiform growth pattern. Plexiform schwannoma must be distinguished from plexiform neurofibroma because of the propensity of the latter for malignant degeneration. Although plexiform schwannoma usually arises sporadically, it can be rarely associated with neurofibromatosis type 2. We report two cases of plexiform schwannoma. One was single sporadic lesion on the abdomen of a 28-year-old woman. The other showed multiple plexiform schwannomas associated with bilateral acoustic neuromas.

흰독나방(Euproctis similis) 유충에 의한 피부염

김민구 ( Min Gu Kim ),노낙경 ( Nark Kyoung Rho ) 대한피부과학회 2006 대한피부과학회지 Vol.44 No.8

The yellow-tail moth Euproctis similis, belongs to the genus Euproctis (Lymantriidae) and has a wide distribution within Korea, Japan, China and Europe. Contact with the `urticating hairs` of the Euproctis similes caterpillar induces dermatitis due to the combination of mechanical and chemical mechanisms. Clinically, patients with caterpillar dermatitis show wheals in the early stage and/or erythematous papules in the late stage after contact with the spicules. We report 5 young soldiers who developed pruritic wheals and erythematous papules on their upper back after contact with the hairs of the Euproctis similies caterpillar. (Korean J Dermatol 2006;44(8):984~987)

지네 교상 29예에 관한 임상적 고찰

김민구 ( Min Gu Kim ),김정아 ( Jung Ah Kim ),노낙경 ( Nark Kyoung Rho ),김범준 ( Beom Jun Kim ),김원석 ( Won Serk Kim ),이동윤 ( Dong Youn Lee ),이주흥 ( Joo Heung Lee ),양준모 ( Jun Mo Yang ),이일수 ( Eil Soo Lee ) 대한피부과학회 2006 대한피부과학회지 Vol.44 No.9

Background: The relative lack of knowledge and interest in arthropod bites has made it difficult to investigate centipede envenomation in Korea. Objective: To describe the epidemiology and clinical characteristics of centipede bites in Korea. Methods: A prospective study of clinical manifestations in patients with centipede bites was performed during the period of May 2004 to April 2005. Factors investigated included sex, age, location and time of assaults, affected parts of the body, signs and symptoms, treatment modalities, and complications. All centipedes that were involved were brought to the clinic, examined, and species-identified. Results: A total of 29 cases of centipede bite were identified. Scolopendra subspinipes was the causative centipede in all cases. Centipede bites occurred exclusively in summer (June, July, and August). Most of the bites which occurred during the daytime happened outdoors, whereas most nocturnal assaults happened indoors. All patients were bitten on an exposed area and the fingers (37.9%) were the most frequent sites of involvement. Local reactions developed at the bitten sites and usually remained localized. Erythema (100%) and local swelling (79.3%) were the most prominent features. The majority of patients did not show severe systemic symptoms. Most lesions healed completely within a week, without complications. Conclusion: Centipede bites are a common occurrance in rural and island areas during the summer season. Dermatologists need to be aware of the clinical manifestations in order to make an appropriate diagnosis and proper treatment decision. (Korean J Dermatol 2006;44(9):1037~1043)

소와 각질융해증 133예에 대한 임상적 고찰

김민구 ( Min Gu Kim ),김정아 ( Jung Ah Kim ),노낙경 ( Nark Kyoung Rho ),김범준 ( Beom Jun Kim ),김원석 ( Won Serk Kim ),이동윤 ( Dong Youn Lee ),이주흥 ( Joo Heung Lee ),양준모 ( Jun Mo Yang ),이일수 ( Eil Soo Lee ) 대한피부과학회 2006 대한피부과학회지 Vol.44 No.10

Background: Pitted keratolysis (PK) is an acquired, chronic, usually asymptomatic, non-inflammatory, superficial bacterial infection of the stratum corneum of the soles. Corynebacterium species are thought to be the causative organisms of PK. This condition is common in feet of active people wearing sweaty shoes, namely, athletes and soldiers. Objective: To analyze the clinical manifestations of pitted keratolysis. Methods: A total of 133 Korean male soldiers diagnosed with PK (aged between 19 and 33, mean 21.9 years) were included in this study. All patients were investigated between April 2004 and May 2005. Factors investigated included age, location, duration, date of visit, physical examination, subjective symptoms, associated medical conditions, and treatment modalities. All patients were examined carefully to verify accompanying erythrasma or trichomycosis axillaris (TMA). Results: About half of the patients visited our department in spring (March, April, and May). However, PK was found in all the seasons. The ball of the foot was the most frequently involved site (92.5%). The big toe (72.2%) was also a frequent site of involvement. Forty-five patients (41.7%) had coexistent erythrasma, 22 (20.4%) had TMA, and 14 (13.0%) had a simultaneous presence of both erythrasma and TMA. Hyperhidrosis (98.5%) and foul odor (95.5%) were the main complaints in most of the patients. Other symptoms associated with PK were sliminess (38.3%), burning (23.3%), itching (18.8%), and prickling (13.5%) sensations. Various treatment modalities such as topical antibiotics, topical antifungal agents, and oral erythromycin have been used. All lesions subsided within 1 month after treatment. Although recurrence rate was high (64.3%), parameters such as period of prevalence, size and shape of the lesion, and treatment modality were not associated with the recurrence rate. Conclusion: The present study provides basic clinical information on PK, which is a common condition of the feet of Korean male soldiers. (Korean J Dermatol 2006;44(10):1165~1170)