고주파 열치료 후 간세포암: 재발양상과 영향인자$^1$

남경진,오종영,최종철,박병호,이영일,Nam, Gyeong-Jin,O, Jong-Yeong,Choe, Jong-Cheol,Park, Byeong-Ho,Lee, Yeong-Il 대한영상의학회 2002 대한영상의학회지 Vol.46 No.2

목적: 간세포암의 고주파 열치료 후 재발양상과 재발에 영향을 미치는 인자에 대해 알아보았다. 대상과 방법: 조직 생검이나 종양표식물질, 삼중기 나선식 CT 소견으로 진단된 간세포암 환자 중 1999년 5월부터 2000년 3월까지 완전 괴사를 목적으로 고주파 열치료를 시행한 69명의 82개 종양을 대상으로 하였다. 대상 병변은 초음파에서 잘보이는 종양으로 개수가 4개 이하이고 종양의 직경이 5 cm 이하로,다른 치료를 받은 적이 없는 환자로 국한하였다. 치료 후 적어도 6개월 이상 삼중기 나선식 CT를 시행하여 종양의 크기, 간문맥과 인접 여부, CT에서의 형태, Child-Pugh 분류 등급,시술 전 알파 태아단백 수치의 인자가 각각 완전 괴사율과 경계면 재발율에 미치는 영향을 후향적으로 분석하였고, 환자 별로 시술 전 알파 태아단백 수치, Child-Pugh 분류 등급, 종양의 다발성이 새로운 병변의 출현에 미치는 영향을 후향적으로 분석하였다. 결과: 고주파 열치료 후 CT 추적 기간은 평균 8.95개월 (6-14개월)로 완전 괴사율은 91%이었고 경계면 재발율은 12%였다. 종양의 크기가 클수록, 종양이 간문맥과 인접한 위치에 있을 때 낮은 완전 괴사율과 높은 경계면 재발율을 보였다. 새로운 병변의 출현율은 19.4%로 알파 태아단백 수치가 높을수록, 종양이 다발성일수록 새로운 병변의 출현율이 높았다. 결론: 간세포암의 고주파 열치료 시 재발 양상과 재발에 영향을 미치는 상기 인자들을 명확히 인식하고 보다 조기에 적절히 시술을 한다면 간세포암에 대한 치료 효과를 향상시킬 수 있을 것으로 사료된다. Purpose: To evaluate patterns of recurrence and factors which influence them in radiofreqency (RF) ablation for the treatment of hepatocellular carcinoma (HCC). Materials and Methods: Between May 1999 and March 2000, 69 patients with 82 HCCs underwent RF ablation for complete necrosis. They were diagnosed by tissue biopsy or tumor marker, and the results of triphasic spiral CT. The indications were that nodular lesions were clearly visualized at sonography, less than 5 cm in size and less than four in number, and that patients had no history of previous treatment. Local therapeutic efficacy such as complete necrosis and marginal recurrence, and new lesions were evaluated by means of triphasic spiral CT performed at least six months after the completion of ablation. We then analyzed the correlation between local therapeutic efficacy and various influential factors such as tumor size, whether the tumor was attached to the portal vein, gross morphology, Child-Pugh classification, and $\alpha$- fetoprotein level before the procedure, as well as the correlation between new lesions and influential factors which included the $\alpha$-fetoprotein level before the procedure, Child-Pugh classification, and multiplicity per person. Results: During a mean follow-up period of 8.95 (range, 6-14) months after RF ablation, the rate of complete necrosis and of marginal recurrence was 91% and 12%, respectively. When a tumor was larger and was attached to a large branch of the portal vien, the incidence of incomplete necrosis and marginal recurrence was greater. The occurrence rate of new lesion was 19.4%. When the $\alpha$-fetoprotien level before the procedure was higher and a tumor was multiple in number, new lesions occurred more frequently. Conclusion: Sufficient knowledge of patterns of recurrence and the factors which influence them might improve the therapeutic effects of RF ablation in patients with HCC.

Legg-Calve-Perthes 병에 대한 골신티그라피 소견

남경진 대한영상의학회 1983 대한영상의학회지 Vol.19 No.1

The pathology of Legg-Calve-Perthes disease be can described as a vascular disturbance leading to necrosis and subsequent revascularization of the femoral epiphyseal ossification center. The regional distribution of bone-seeking radiopharmaceuticals in the skeleton can depend on a number of factors, but bone blood flow is a major physiological determinant of regional skeletal uptake of Tc-99m polyphosphate and bone imaging may thus be used for the detection of areas with both decreased and increased vascular supply. The authors analyzed the scintigraphic findings of 14 cases of Legg-Calve-Perthes disease at Kyung Hee University Hospital from Mar. '81 to Oct. '82. The results were as follows : 1. Scintigraphy revealed area of absent radioactivity in 14 cases ; lateral 2/3 portion of the femoral epiphyaseal ossification center was involved in 9 cases among 14 cases, and also increased radioactivity in epiphyseal ossification center, epiphyseal plate, or proximal metaphysis of femur were assoclated in 7 cases. 2. Three cases had radiographically normal hip, whereas scintigraphy revealed distinctly absent radioactivity in femoral epiphyseal ossification center. 3. Magnification of hip imaging using a pinhole collimator provided good definition of presence and extent of pathologic defect or uptake in epiphyseal ossification center, epiphyseal plate, and metaphysis. Bone imaging provided earlier and more accurate information concerning the extent of the necrotic and revascularization process of Legg-Calve-Perthes disease than the radiographs alone.

간질환에 대한 신티그라피의 진단적 의의 및 초음파진단과의 비교연구

남경진 대한영상의학회 1982 대한영상의학회지 Vol.18 No.3

A Tc-99m sulfur colloid hepatic scintigraphy is often the first imaging modality empolyed in the evaluation of the patient with suspected liver disease, since the hepatic scintigraphy is not only highly sensitive, low expense and easy of performance but also provides both sturctural and functional information of the liver. The author analyzed the scintigraphic finding in 304 patient proven various hepatic disease and 58 normal liver, and also retrospectively analyzed the result of hepatic scintigraphy and ultrasonography of the liver in 117 patients. The results were as follows: 1. The overall sensitivity and specificity of hepatic scintigraphy in the liver disease is 91% and 67%, respectively. 2. On the evaluation of the diffuse parenchymal parenchymal disease of liver, the scintigraphy was found to be highly sensitive (88%) and also specific image patteerns were found in cirrhosis. 3. The hepatic scintigraphy was highly sensitive (92%) in the detection of the focal lesions of liver. 4. The ultrasonography was capable of differentiating solid and cystic masses which were detected on scintigraphy, while scintigraphy was more sensitive in detection of hepatocellular disease. 5. Tc-99m sulfur colloid imaging remained the preferred inital screening method in patients with suspected liver disease, while ultrasonography should be done for those patients with a prior suspicious findings.

Left Circumflex Coronary Artery Fistula Connected to the Right Bronchial Artery Associated with Bronchiectasis: Multidetector CT and Coronary Angiography Findings

남경진,추기석 대한영상의학회 2013 대한영상의학회지 Vol.68 No.4

Coronary to bronchial artery fistula is a rare vascular anomaly secondary to enlargement of pre-existing vascular anastomosis between the coronary and bronchial arteries. This occurs when there is a constant disturbance of the pressure equilibrium involving either coronary or broncho-pulmonary disorder. Localized bronchiectasis is the most common related condition in patients with a coronary to bronchial artery fistula. Herein, we report on a case of a large left circumflex coronary artery to right bronchial artery fistula associated with bronchiectasis.

What factors make portal sites perform well in Korea?

남경진,권영선 한국정보사회학회 2013 정보사회와 미디어 Vol.- No.27

As the market size of portal business increases, the competition among portal sites has also increased in terms of both service quality and diversity. Google is the most powerful portal site in the world, whose market share is 65.2% of the world market, but this is not the case in Korea. The purpose of this study is to find the order of importance among hierarchical-factors which affect users in their choice of portal sites. Using an AHP analysis based on survey data, the order of importance of primary factors, first, information offering, followed by, in order, entertainment & additional services, interactivity, and usability. Including sub-factors of the primary factors, the order of importance is accuracy and quickness of information offering, diversity of entertainment & additional services and an understanding of usability. The results also show that Naver and Daum are preferred to Google, implying that the main role of portal site has evolved from gateway to access to the internet for searching information to total brand sites of diverse activity, which is consistent with the ranking of the market shares noted above.

국내 다문화교육역량 연구동향 분석

남경진 한국다문화교육학회 2023 다문화교육연구 Vol.16 No.2

The purpose of this study was to investigate the domestic research trend of multicultural education competency. Using RISS, 31 papers published in major Korean academic journals from 2012 to 2023 were selected and analyzed for this study. The papers were analyzed for research periods, research topics, research methods, and subjects of research. The research results were as follows. First, multicultural education competency has been continuously studied since 2012, with the most research conducted in 2018 and decreasing since then. Second, studies related to multicultural education competency were mainly published in journals pedagogy-related dealing with multicultural, educational, and learners. Third, the research topic that garnered the highest popularity was the examination of factors influencing multicultural education competency. Fourth, research on multicultural education competencies was mainly conducted using quantitative research methods. Fifth, it was verified the most of the subjects of the study were pre-service teachers. Based on these results, the future direction of multicultural education competency research was discussed, and it was suggested that a wider variety of research methods be used. 본 연구는 향후 다문화교육역량의 국내 연구동향을 살펴보기 위하여 2012년부터 2023년까지 한국연구재단의 등재지 및 등재후보지에 게재된 연구 중 다문화교육역량에 대한 31편의 논문을 선정하였다. 연도별 추이, 연구주제, 연구대상 등을 분석틀로 하여 연구동향 및 특징을 분석하였다. 연구결과는 다음과 같다. 첫째, 다문화교육역량 관련 연구는 2012년부터 지속적으로 연구되어왔으며 2018년 가장 많은 연구가 이루어졌으나 이후 다시 감소하였다. 둘째, 다문화교육역량 관련 연구들은 주로 다문화, 교육, 학습자를 다루는 교육학 관련 학술지에 주로 게재되고 있었다. 셋째, 다문화교육역량 관련 연구주제는 다문화교육역량의 영향에 대한 요인연구 유형이 가장 많았다. 넷째, 다문화교육역량의 연구는 주로 양적연구를 활용하여 이루어졌다. 다섯째, 다문화교육역량의 연구대상은 예비교사와 교사를 대상으로 하는 시도가 가장 많은 것으로 검증되었다. 이러한 결과를 토대로 다문화교육역량 연구의 향후 방향에 대해 논의하였으며 다양한 연구방법을 활용할 필요가 있다는 점을 시사하였다.

Do Real-time Interactions Increase Audience Satisfaction for Online Live Video Streaming Service?: The Case of AfreecaTV in Korea

남경진,김혜진,권영선 한국정보사회학회 2018 정보사회와 미디어 Vol.19 No.2

People’s behavior of multimedia consumption is now changing from passive watching to active or interactive watching. After opening of AfreecaTV, a leading Korean online personal broadcasting service, broadcasting jockeys broadcast their multimedia content, such as videos, shows, sports games and online games, with their own comments. The key feature distinguishing Afreeca TV from traditional broadcasting services is the interactivity between broadcasting jockeys and the audience. This paper tries to examine whether this interactivity could be interpreted as a new powerful viewing motive inducing the audience to choose a certain AfreecaTV channel by applying the uses and gratifications theory. Broadcasting jockey interaction was identified as an important factor that affects audience activity and satisfaction. Real-time interactions with both other audience members of the same interest was also found to be a critical factor in inducing audience to watch online live video streaming services. Along with the self-motivation to interact with other members of the audience, the effort of broadcasting jockeys to interact with audiences could play a critical role in increasing the audience’s motivation to viewing AfreecaTV.

나선식 CT를 이용한 췌장의 역동적 연구 : 조영제의 주입량에 따른 비교

남경진 대한영상의학회 1998 대한영상의학회지 Vol.38 No.2

Purpose: To determine the hemodynamics of the pancreas by investigating the enhancement patterns of pancreaticparenchyma, as seen on spiral CT, after the administration of various amounts of contrast medium, and to determineoptimal scan time by knowing the peak time of normal pancreatic parenchyma. Materials and Methods: Between January1995 and April 1997 55 cases of normal abdominal CT with dynamic enhancement study on pancreas, the subject were38 cases(28 persons) with good image, aged 21-65 years, men were twenty-one and women were seven. Non-ioniccontrast medium, 30ml(n=15), 60ml(n=9), 990ml(n=7), and 120ml(n=7) were injected at a rate of 3ml/sec. From 20sec. after the start of injection, 15 images were obtained at 3-sec intervals. Before and after injection, R.O.I.was applied to each image, and for the aorta and pancreatic parenchyma, Hounsfield units(H.U.) were measured; timeof enhancement and maximal H.U. were also measured. Results: After 30, 60, 90, and 120ml of contrast mediuminjection, mean maximal H.U. of pancreatic parenchyma was 36$\pm$7, 54$\pm$6, 68V13, and 92$\pm$8, respectively; mean valueat peak parenchymal enhancement of the pancreas was 27$\pm$3, 32$\pm$3, 42$\pm$3, and 52$\pm$3, respectively. Time intervalsof maximal enhancement of aorta and pancreatic parenchyma could not be obtained in 30ml injection, but 5,4$\pm$2.5,4.2$\pm$1.6, and 6.0$\pm$2.1sec in 60, 90, and 120ml injection, respectively. Conclusion: Maximal H.U. of parenchymalenhancement of the pancreas is directly proportional to the amount of injected contrast medium and the peak timeof parenchymal enhancement was 12sec after the injection of contrast material. Time interval of maximalenhancement of aorta and pancreatic parenchyma was 5.2$\pm$2.1sec.

Legg-Calve-Perthes 병에 대한 골신티그라피 소견

남경진,이선화,김은경,김순용 대한핵의학회 1983 핵의학 분자영상 Vol.17 No.1

전산화 단층 촬영 척수조영술의 방사선학적 고찰

남경진 인제대학교 1989 仁濟醫學 Vol.10 No.2

최근 2년 6개월간 인제의대 부산 백병원에 내원하여 Iopamidol제제를 척수 강내로 주입하여 척수조영술과 CT 척수조영술을 시행한 278명의 환자를 대상으로 후향적 분석을 하여 다음과 같은 결론을 얻었다. 척수조영술상 경막낭이 완전히 차단된 경우, CT 척수조영술은 차단 부위 이하 또는 그 이상의 병변을 잘 관찰할 수 있어 차단 원인과 침범 범위를 정확히 볼 수 있었다. 요추간판 탈출증에 있어 CT 척수조영술은 척수조영술과 비슷한 진단율을 보였지만 요추간판 석회화와 진공 현상 뿐만 아니라, 추관절 병변, 인대비후, tropism, Schmorl's node 등을 더 잘 나타내었다. CT 척수조영술은 척수종양과 감염의 종류와 주위 조직으로의 파급 정도를 평가하는데 도움이 되었다. CT 척수조영술은 또한 선천성 질환의 병변의 종류 및 침범 범위, 그리고 연관된 다른 기형을 잘 볼 수 있었다. 척수 손상에 있어서 CT 척수조영술은 척수 조영술에 비해 척추강내 출혈, 골편 및 손상의 정도를 평가하는데 매우 유용하였다. Computed Topography with administration of intrathecal contrast material (Iopamidol) was evaluated retrospectively in 278 patients. In all patients, both myelography and CT myelosraphy was performed. 1) On high grade subarachnoid obstruction in myelography, CT myelography demonstrates the cephalad or caudal extent of block with nature and extent of the lesion. 2) On disc disease, CT myelography well demonstrates protruded disc itself with disc calcification and vaccum phenomenon, as well as associated findings such as facet joint change, thickening of ligament flavum, posterior bony spur, tropism, Schmorl's node, etc. 3) CT myelography is helpful in evaluating the nature and paraspinal extent of infection and tumor. 4) In spine trauma, CT myelography is also useful in the evaluation of hemorrhage or bony fragment in spinal canal and spinal cord injury. 5) CT myelography also clearly demonstrates the extent and nature of the congenital anomalies such as spinal dysraphism or epidural cyst, with associated anomalies. 6) So, CT myelography should be considered as valuable diagnostic modality in the evaluation of various spinal diseases.