風池(GB20)의 天麻藥鍼이 Intraluminal Filament 삽입술에 의하여 유발된 白鼠의 뇌허혈에 미치는 영향

나건호,윤대환,나창수,채우석 대한침구의학회 2008 대한침구의학회지 Vol.25 No.1

Objectives : Delayed neuronal death(DND) of pyramidal neuronsin the CA1 regions of the hippocampus has been extensively studied following global brain ischemia, whereas little is known about DND in this highly vulnerable brain region after focal brain ischemia. The aim of the present study was to investigate the effect of Gastrodiae Elata(GA) pharmacopuncture on hippocampal neuronal apoptosis in rats with focal brain ischemic injury. Materials and methods : The neuroprotective effects of water extracts of GA were investigated in middle cerebral artery occlusion(MCAo) of Sprague-Dawley(SD) rats. Seventy-five healthy SD ratswere randomly divided into five groups following MCAo : control group with focal ischemia, saline injection group, pharmacopuncture group GA-1(0.0007㎎/㎖/g), pharmacopuncture group GA-2(0.00035㎎/㎖/g), phar- macopuncture group GA-3(0.00014㎎/㎖/g). Results : The intensity of mGluR5 increased in the GA-1 group. The intensity of Bax and the Bax/Bcl-2 ratio decreased in the GA-1 group. The intensity of Bcl-2 increased in all the GA groups. The density of neurons stained by Cresyl violet and ChAT increased in the GA-1 group. Conclusions : Our study suggests that GA pharmacopuncture at GB20 showed anti-apoptotic and neuro- protective effects on cholinergic neuronsin focal cerebral ischemia caused by stroke in SD rats.

특발성안면신경마비환자군과 건강검진군의 양도락 진단결과에 대한 비교연구

나건호,이동현,정영표,정효근,김현수,류충열,조명래,채우석,설재욱 대한침구의학회 2006 대한침구의학회지 Vol.23 No.4

Objectives : The aim of the present study was to evaluate Yandorak for the wide inflection and establishment of a diagnostic system. Methods : We analyzed the measurement value of Yandorak on fifty one patients with idiopathic facial paralysis and eighty four healthy persons from April 1, 2005 to March 1, 2006 by using Yangdorak(YDRAK-94N, Sord Medicom Co., Korea). Statistical analysis was performed using the SPSS 11.0 for Windows, Mann-Whitney test for the comparisons followed side(Right and Left), sex, palsy localization in idiopathic facial paralysis and normal group and one-way ANOVA(Kruskal Wallis) for the comparisons followed age. P < .05 was considered significant statistically. Results : The difference of the electric current value of all meridian except Bladder(BL) of normal group on both side extremity was not significant statistically. Electric current value of all meridian except Gall-Bladder(GB) was more higher in idiopathic facial paralysis group than in normal group. The measurement value of Yandorak followed sex and palsy localization were not significant statistically. Conclusion : It is suggested that the measurement value of six Hand Yang & Eum channel, Liver Meridian of Foot Gworeum(厥陰) and Stomach Meridian of Foot Yangmyeong(陽明) is more higher in idiopathic facial paralysis group than in normal group.

五行鍼과 六氣鍼을 응용한 뇌경색환자 치험 1

나건호,채우석,조명래,이동현,정영표,김현수,류충열 경락경혈학회 2006 Korean Journal of Acupuncture Vol.23 No.1

Objectives : The purpose of this case is to report the improvement after treatment about a patient with cerebral infarction by Sa-Am`s Ohaeng-acupuncture and Liuqi-acupuncture. Methods : We treated the patient with acupuncture therapy from 6th September 2004 to 15th November 2004 by reinforcing Dadun(Liv 1) Zusan Li(S 36) Quchi(Li 11) and reducing Taibai(Sp 3) on the basis of Etiological Analysis and Differenciation of Endogenous Wind caused by Damp Phlegm and heat.

糖尿1號方의 藥鍼 및 口腔投與가 Streptozotocin에 의한 흰쥐의 糖尿病性 腎症에 미치는 영향

나건호,조명래,조수인 대한침구의학회 2005 대한침구의학회지 Vol.20 No.6

Objective : The present study was carried out to investigate the preventive effect of Anti-diabetic prescription 1(AD-1) on streptozotocin(STZ)-induced diabetic nephropathy. Methods : AD-1 consists of eleven herbs that have an effect on diabetes mellitus. AD-1 was given to rats with the combination of oral administration and herbal-acupuncture stimulation. The experimental animals were divided into 3 groups : normal group of rats, control group of STZ-induced diabetic rats, sample group with AD-1 treatment. Experimental diabetes was induced by the injection of STZ(60㎎/㎏) to the rat via the peritoneum. The effect of AD-1 on STZ-induced diabetic nephropathy was observed by measuring the serum level of creatinine and BUN. Urine secretion of albumin for 24 hours and urine level of glucose measures too. Anti-oxidative stress of AD-1 administration in living body was estimated by measuring lipid peroxide and GSH content in cortex of kidneys. Results : STZ induced increase of serum creatinine, BUN and albumin secretion were lowered by AD-1 treatment. Conclusions : The AD-1 treatment showed protective effect on rat diabetic nephropathy model, and action mechanism of the effect was thought to be concerned with anti-oxidative stress.

당뇨1호방의 약침 및 구강투여가 Streptozotocin에 의한 흰쥐의 당뇨병성 신증에 미치는 영향

나건호,조수인,조명래 대한침구의학회 2005 대한침구의학회지 Vol.22 No.5

Objectives : The present study was carried out to investigate the preventive effect of Anti-diabetic prescription 1(AD-1) on streptozotocin(STZ)-induced diabetic nephropathy. Methods : AD-1 consists of eleven herbs that have an effect on diabetes mellitus. AD-1 was given to rats with the combination of oral administration and herbal-acupuncture stimulation. The experimental animals were divided into 3 groups : normal group of rats, control group of STZ-induced diabetic rats, sample group with AD-1 treatment. Experimental diabetes was induced by the injection of STZ(60㎎/㎏) to the rat via the peritoneum. The effect of AD-1 on STZ-induced diabetic nephropathy was observed by measuring the serum level of creatinine and BUN. Urine secretion of albumin for 24 hours and urine level of glucose measures too. Anti-oxidative stress of AD-1 administration in living body was estimated by measuring lipid peroxide and GSH content in cortex of kidneys. Results : STZ induced increase of serum creatinine, BUN and albumin secretion were lowered by AD-1 treatment. Conclusion : The AD-1 treatment showed protective effect on rat diabetic nephropathy model, and action mechanism of the effect was thought to be concerned with anti-oxidative stress.

Meralgia Paresthetica 치료(治療) 1례에(例) 대한 증례보고

나건호,박은주,신정철,이동현,이삼로,류충열,윤여충,조명래,Na, Gun-ho,Park, Eun-ju,Shin, Jeong-cheol,Lee, Dong-hyun,Lee, Sam-ro,Ryu, Chung-ryul,Yoon, Yeo-choong,Cho, Myung-rae 대한침구의학회 2005 대한침구의학회지 Vol.22 No.1

대퇴부 작열감, 동통, 부종을 주소로 내원한 환자 1례를 대상으로 점액낭염에 의한 meralgia paresthetica의 진단 하에 한방적 치료를 시행하여 임상 양상을 관찰한 결과 다음과 같은 결론 을 얻었다. 1. meralgia paresthetica는 포착성 신경병증으로 외측 대퇴 피 신경이 압박되거나 손상되어, 대퇴부 전외측에 감각 저하, 이상 감각 및 작 열감을 호소하는 질환이다. 2. meralgia paresthetica는 한방적으로 '비병(痺病)', '마목(麻木)' 등의 범주에 해당하며 양혈산한통락(養血散寒通絡)의 치법을 활용할 수 있다. 3. 통비(痛痺)와 착휘(着輝)에 해당하는 meralgia paresthetica환자에게 가미활혈탕(加味活血湯) 투여 및 환측(患側)의비관(?關) 복토(伏兎) 충문(衝門) 풍시(風市) 족삼리(足三里) 등의(等) 혈위(穴位)에 자침(刺針)과 습식부항(濕式附缸)을 시술하여 6일만에 현저한 치료 효과를 보았다. 4. 환자는 고관절의 ROM에 있어서 초진시 신전제한 $60^{\circ}$였으나, 5회의 치료 후 신전제한 $0^{\circ}$로 회복되었으며 퇴원시 대퇴부 인통(引痛), 부종(浮腫), 발열(發熱) 등의 증상이 모두 경감되었다.

Meralgia paresthetica 治療 1例에 대한 증례보고

나건호,박은주,신정철,이동현,이삼로,류충열,윤여충,조명래 대한침구의학회 2005 대한침구의학회지 Vol.33 No.2

Objectives : The purpose of this case is to report the improvement after treatment about a patient with meralgia paresthetica.. Methods : We treated the patient with acupuncture therapy and Herbal medication from 11th October 2004 to 15th October 2004 by evaluating femoral function with VAS score and R.O.M of femur joint. Results : After 5 times of treatment, this patient achieved excellent outcome following the technique, showing that clinical symptom as like heating sense, edema and pain was disappeared, VAS changed from 10 to 1 and there was no limitation of ROM of femur. Conclusions : Meralgia paresthetica is a symptom complex that includes numbness, paresthesias, and pain in the anterolateral thigh, which may result from either an entrapment neuropathy or a neuroma of the lateral femoral cutaneous nerve(LFCN). Oriental medical treatment for meralgia paresthetica resulted in satisfactory results by diminishing the symptoms progressively during the five days of tretment. Differential diagnosis was based on careful physical examination. More research of meralgia paresthetica is needed.

뇌경색환자 치험 1례를 통한 五行鍼과 六氣鍼의 연구

나건호(Gun-ho Na),이동현(Dong-hyun Lee),정영표(Yeong-pyo Jeong),정효근(Hyo-keun Jeong),이은방(Eun-bang Lee),류충열(Chung-ryul Ryu),조명래(Myung-rae Cho),채우석(Woo-seok Chae) 한의병리학회 2006 동의생리병리학회지 Vol.20 No.3

오행침(五行鍼)과 륙기침(六氣鍼)을 응용한 뇌경색환자 치험 1례

나건호 ( Gun Ho Na ),이동현 ( Dong Hyun Lee ),정영표 ( Yeong Hyo Jeong ),김현수 ( Heong Hu Kim ),류충열 ( Chung Ryul Ryu ),조명래 ( Myung Rae Cho ),채우석 ( U Seok Chae ) 대한경락경혈학회 2006 Korean Journal of Acupuncture Vol.23 No.1

Objectives: The purpose of this case is to report the improvement after treatment about a patient with cerebral infarction by Sa-Am`s Ohaeng-acupuncture and Liuqi-acupuncture. Methods: We treated the patient with acupuncture therapy from 6th September 2004 to 15th November 2004 by reinforcing Dadun(Liv 1)·Zusan Li(S 36)·Quchi(Li 11) and reducing Taibai(Sp 3) on the basis of Etiological Analysis and Differenciation of Endogenous Wind caused by Damp Phlegm and heat. Results: 1. Right hemiplegia improved Gr.Ⅰ to Gr.Ⅳ after acupuncture therapy. 2. we interpreted `reinforcing Dadun(Liv 1) and reducing Taibai(Sp 3)` as using Simjeonggyeok in conjunction with Simseunggyeok on the basis of Sa-Am`s Ohaeng-acupuncture. 3. we interpreted `reinforcing Dadun(Liv 1) and reducing Taibai(Sp 3)` as Excreting Dampness in Spleen on the basis of Liuqi-acupuncture. 4. we interpreted `reinforcing Zusan Li(S 36) and Quchi(Li 11)` as Eliminating Wind-dampness and Menstrual Regulation.

노인성 구강-안면 이상운동증 환자 2례에 대한 증례보고

이동현,나건호,신정철,위통순,류충열,조명래,채우석,윤여충 대한침구의학회 2005 대한침구의학회지 Vol.22 No.5

Objectives : The purpose of this case is to report the improvement after the acupuncture therapy and herbal medicine about two patients with senile oro-facial dyskinesia. Methods : We treated the patient with acupuncture therapy and herbal medicine by evaluating facial, lips, jaw and tongue expression of AIMS(Abnormal Involuntary Movement Scale) and clinical symptom progress. Results : We have recently experienced two cases of senile oro-facial dyskinesia. Two patients were improved significantly through the acupuncture therapy and herbal medicine, so we report it for the better treatment. Conclusion : Oro-facial dyskinesia is stereotyped movements, consisting of smacking and pursing of the lips, lateral deviation and protrusion of the tongue, and occasionally lateral deviation and protrusion of the jaw. Spontaneous oro-facial dyskinesias occur in the elderly and had been said to result from edentulousness. Oriental medical treatment for oro-facial dyskinesia resulted in satisfactory results by diminishing the symptoms progressively during the admission periods. More research of oro-facial dyskinesia is needed.