지식경영은 휴먼 터치로부터

김형회,Kim, Hyeong-Hoe 한국IT전문가협회 2003 소프트웨어세계 Vol.6 No.-

New Integrated Information System for Pusan National University Hospital

김형회,조경원,김혜숙,김주심,김정현,한상필,박춘복,김석,채영문 대한의료정보학회 2011 Healthcare Informatics Research Vol.17 No.1

Objectives: This study presents the information system for Pusan National University Hospital (PNUH), evaluates its performance qualitatively, and conducts economic analysis. Methods: Information system for PNUH was designed by componentbased development and developed by internet technologies. Order Communication System, Electronic Medical Record, and Clinical Decision Support System were newly developed. The performance of the hospital information system was qualitatively evaluated based on the performance reference model in order to identify problem areas for the old system. The Information Economics approach was used to analyze the economic feasibility of hospital information system in order to account for the intangible benefits. Results: Average performance scores were 3.16 for input layer, 3.35 for process layer, and 3.57 for business layer. In addition, the cumulative benefit to cost ratio was 0.50 in 2011, 1.73 in 2012, 1.76 in 2013, 1.71 in 2014, and 1.71 in 2015. The B/C ratios steadily increase as value items are added. Conclusions: While overall performance scores were reasonably high, doctors were less satisfied with the system, perhaps due to the weak clinical function in the systems. The information economics analysis demonstrated the economic profitability of the information systems if all intangible benefits were included. The second qualitative evaluation survey and economic analysis were proposed to evaluate the changes in performance of the new system.

Dimension RxL Max HM기기에서 NT-proBNP 검사평

김형회,이은엽,손한철 부산대학교 병원 암연구소 2008 부산대병원학술지 Vol.- No.23

Background: N-terminal pro-brain type natriuretic peptide (NT-proBNP) has been identified as a promising biochemical marker for congestive heart failure (CHF). Recently, the NT-proBNP assay using electrochemiluminescence method has been developed. We evaluated performance of the NT-proBNP assay and its relationship with Triage BNP assay. Methods : NT-proBNP(DADE BEHRING, Germany) was evaluated for within-run precision, within-day precision, between-days precision, and linearity. With 96 patients samples, NT-proBNP were compared with Triage BNP assay. For reference interval, we tested 120 healthy adult sample under 75years old. Results : The coefficients of variation(CVs) of within-run precision, within-day precision and between-days precision were less than 10%, mostly 6%. The lower reportable limit was 10.1 pg/mL and upper limit was 30,000 pg/mL. The comparison study indicated good agreement between Triage BNP positive results and NT-proBNP, but correlation was not excellent. The reference interval were 85.1 pg/mL for man and 120 pg/mL for woman. Conclusions : NT-proBNP(DADE BEHRING, Germany) showed a good precision and good agreement with Triage BNP positive results, but correlation was not excellent. 배경: 혈장 BNP 측정은 울혈성 심부전의 진단과 평가에 이용되며 또한 급성관상동맥질환 환자의 위험도 평가 및 호흡곤란을 보이는 환자의 감별진단에 이용될 수 있다. 본 연구에서는 자동화학 장비인 Dimension RxL-Max(DADE BEHRING, Germa) 이용하여 NT-proBNP(PBNP) 검사의 정밀도와 일간 변동, 기존의 Triage BNP assay (Biosite Inc., San Diego, USA) 와 상관성 등의 수행능력을 비교하고 한국인의 참고범위를 설정하고자 하였다. 방법 : 3가지 농도의 상품화된 정도관리 물질을 이용하여 검사일내 정밀도, 검사일간 정밀도와를 직선성 평가를 실시하고 상관성평가는 96명의 환자검체를 이용하여 Triage BNP assay와 비교하였고, 참고범위는 75세미만의 건강성인 120 명 을 대상으로 설정하였다. 결과: 정밀도 분석은 검사 간 변이계수 (between-run coefficient of variation), 일간변이계수 (b etween-day coefficient of variation) 빛 총변이계수(total coefficient of variation) 모두 10%이하이고 대부분 6%이하의 우수한 결과를 보였고, NT-proBNP 검사의 보고가능 범위는 하한치가 10.1pg/mL, 상한치가 30,000 pg/mL 이었다. Triage BNP와 비교에서 불일치율이 11.4%였고 Triage BNP에서 cut-off이상을 보인 환자의 일치율은 98.1%로 상당히 좋았다. 75세 미만의 건강성인에서 97.5th percentile 을 기준으로 참고범위의 설정은 남자는 85.1 pg/mL, 여자는 120 pg/mL 이었다. 결론 : NT-proBNP는 우수한 정밀도와 직선성을 보여주었고 기존의 검사와 비교에서 검사결과의 일치율은 높았지만 상관관계는 낮았다.

우리나라 年金保險에 關한 考察 : 公務員 年金制度를 中心으로

金亨會 서울大學校保建大學院 1970 公衆保健雜誌 Vol.7 No.2

It is one of the current policies of this country to introduce social insurance and expand it step by step. In order to obtain data required for the extension and development of pension insurance aimed at supporting the living of retired and aged persons, wisits were made to the Pension Bureau of the Ministry of Gvernment Administration from September 1 to October 20, 1970. As the results of studies and analysis conducted of data thus obtained on the operating status of the government employees' pension system, the following conclusion was reached: 1) As of the end of 1970, the total number of government employees suject to the application of the Government Employees's Pension Law was 410,150. Ordinary category employees constituted 49.1 per cent or the greatest proportion, educational employees 30 per cent, manual workers 20.7 per cent, and judges 0.2 per cent or the smallest proportion. 2) The government employees were broken down by seniority of service into the following gro-ups those with seniority one year to five years constituted 51.7 per cent or the greatest proportion, those with seniority of six 10 years 22.5 per cent, those with seniority of 11 to 15 years 9.9 per cent, those with seniority of 16 to 20 years 13.2 per cent, and those with seniority of more than 20 years only 2.7 per cent. 3) The average annul increase rate for the number of government employees entitled to benefit from the pension system was 5.9 per cent. Their retirement rate was6.1 per cent. 4) The government employees who retired in 1970 were broken down into the following groups of seniority:those with seniority of one year toi four years constuted 49.8 per cent or the greatest proportion, those with seniority of five to none years 26.5 per cent, and those with with seniority of 15 to 20 years 11.2 per cent or the smallest proportion. 5) Studies should be made to devise the method of benefiting the government employees excluded from the application of the Government Employees' Pension Law and to set the scope of application under a consolidated system. 6) The greatest of the financial resources for the apyment of insurance money was procured by way of contribution made by the Government and premiums paid by employees. The rates of both the contribution made by the Government and the premium paid by employees were same at 2.3 per cent from 1962 to 1968, 2.5 per cent in 1969, and 5.5 per cent in 1970. 7) The payment of pension constituted the greatest percentage of insurance money paid, and the accumulated reserve funds and the reserve funds constituted large proportions, while managerial expenses occupied only 1 to 3 per cent. 8) The increase rate of the Pension Fund reached an average of 36 per cent per annum. Its amount increased from \1, 730,000,000 in 1962 to 13,560,000 at the end August 1970. 9) The rates of contribution made by the Government and premium paid by employees under the pension insurance policy should be determined in such a way as to insure their we living of government employees and the promotion of their welfare As measures incidental to the merger of the short-term insurance money(formedical treatment) and the long-term insurance mo-ney(for the payment of pension), it is recommended that the contribution rates be readjusted. 10) There were 16 kinds of insurance money comprising seven kinds of short-term insurance money and nine kinds of long-term insurance money. The short-term insurance money was to be paid for medical treatment, delivery of child, funeral and ritual, while the long-term insurance money was to be paid for retirement, injury, and the living expenses of breaved families. 11) The average annual payment of insurance money was \38,429 per case. The amount of short-term in surance money was\5,039 and that of long-term insurance money \86,050. 12) The average annual amount of contribution by each employee was \1,750 in 1962, \3,060 in 1967, and \6,900 in 1969. The average amount of benefit given to each employee reached \342 in 1962, \4,600 in 1967, and \13,600 in 1969. 13) The government employees' pension system is a safe and permanent means of insuring their living. Its effects are being sharply elevated. Individual beneficiaries are free to choose a lump-sum payment or yearly installment payments. The ration of insurance money to the amount of contribution made by the beneficiary was 9.3-fold under the government employees' pens-ion system the corresponding figure under the average rivate insurance policy was only 1.3-fold. 14) It is the fundamental objective to seek the qualitative improvement of insurance and to make it realistic as a means of supporting the living of the insured. 15) A single insurance prganization is recommended as a prerequisite to the consolidation of pension insurance. Also essential for the operation of insurance is to train skilled insurance personnel and appropriately assign them. In view of the improtance of statistics concerning insurance, the establishment of an organization exclusively engaged in statistics is desirable.

Laccaria laccata B.의 Phytohemoagglutinin에 關한 硏究

金亨會 고려대학교 의과대학 1973 고려대학교 의과대학 잡지 Vol.10 No.3

만성호중구성백혈병 2예

김형회,여승민,문건식,이은엽,김순호 대한임상검사정도관리학회 1994 臨床檢査와 精度管理 Vol.16 No.2

네트워크 사회에 성공하려면

김형회,Kim, Hyeong-Hoe 한국IT전문가협회 2001 소프트웨어세계 Vol.5 No.-

An Improved Auto-Generation System to Obtain Reference Intervals for Laboratory Medicine

김형회,홍해숙,김신영,트란퉁,이지민,김화선,조훈 대한의료정보학회 2010 Healthcare Informatics Research Vol.16 No.1

Objectives: Reference values are highly required parameters for all tests in the clinical laboratory, and the supplementary provision of reliable reference intervals is an important task for both clinical laboratories and diagnostic test manufacturers. Despite the progress that has been made in the conceptual aspects of reference intervals, in practice their use is still not completely satisfactory. Most of the laboratories have used various methods to calculate statistic-based reference intervals,and they have mainly focused on extracted data, yet its use is considerably limited. We had to deal with the inconvenience of using a number of programs (SPSS or SAS, MS Excel) in order to calculate the results of reference intervals. Methods: In order to obtain standardized reference intervals, we developed an integrated program that can calculate, by a nonparametric method, reference intervals with using the Clinical and Laboratory Standards Institute (CLSI) processes as its guideline. We also developed a grouping interface that enables users to customize classification of each group (age, gender, blood group,race, etc) when calculating reference intervals. Results: To verify the developed program, we compared the reference intervals of the current data on 281 persons for 8 total areas, and the reference intervals were was already calculated beforehand with by using this new program. As a result, both results perfectly matched. Conclusions: This integrated program will be convenience for calculating reasonable values through continual datainspection at an inspection lab for calculating reference intervals. The newly developed program will improve the consistency and reliability of the statistics on reference intervals.

만성 C형 간염환자에 있어서 단핵구의 Th1/Th2 사이토카인 생성에 관한 연구

김형회,이은엽,손한철 대한진단검사의학회 2002 Annals of Laboratory Medicine Vol.22 No.4

배경 : C형 간염바이러스(HCV)에 감염되면 환자의 약 50%는 만성간염을 일으키며 이 중 약 반은 간경변 혹은 간암으로 진행한다. HCV 감염환자에서 만성화와 질병의 진행에 따른 면역조절기전을 알아보기 위하여 IFN- , IL-12, IL-2의 Th1 사이토카인과 IL-4의 Th2 사이토카인을 이용하여 면역능을 분석하고자 하였다.방법 : 만성 C형 간질환 환자 31명(만성간염 19예, 간경변증12명)과 대조군의 혈청과 배양된 말초혈 단핵구에서 생성된IFN- , IL-12, IL-2, IL-4 사이토카인을 효소면역법으로 측정하였다. 결과 : 혈청 IFN- 치는 만성간염과 간경변증에서 대조군보다유의하게 높았다(P<0.05). 대조군의 단핵구자연생성 IFN- 치는 모두 검출농도 이하로 낮았지만 만성간염에서는 42%, 간경변증은 75%에서 검출되어 대조군과 유의한 차이가 있었다( P<0.05). PHA로 자극한 단핵구에서 생성된 IFN- 치는 간질환군에서 대조군에 비해 유의하게 낮았다(P<0.05). 혈청 IL-12는 대조군 및 간질환군에서 모두 검출되지 않았고 PHA로 자극한 단핵구 생성 IL-12치는 대조군보다 간염군에서 유의하게 낮았다(P<0.01). IFN- 는 IL-12, 림프구 수, 단핵구 수와 유의한 상관관계를 보였고 다른 사이토카인과 상관성은 없었다.

만성 신부전이 있는 혈액투석 환자에서 말초혈 림프구 T세포 아형과 혈청 가용성 CD8(sCD8)치의 분석

김형회,문순영,여승민,김시내,이은엽 대한임상병리학회 1995 대한임상병리학회지 Vol.15 No.3