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        구내 골신장술 후 식립된 전치부 임플란트보철 치험보고

        김한석,김명래,이성근,강상원,김기환,김형섭 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.1

        Objective : This is to report the effectiveness of intraoral distraction osteogenesis for alveolar augmentation in the extremely atrophied alveolar defects and to review the clinical results of the 2 cases. Subjects and Methods : Anterior segmental osteotomy was performed and the trans-oral alveolar distractors(Martin, Germany) were applied in 2 patients with the severe acquired anterior maxillary and mandibular defect. After latent period for 1 week, the osteomized alveolar segments were distracted by 1 ㎜ a day (0.5 ㎜/l turn) for 8 days in case Ⅰ and 0.6 ㎜ a day(0.3 ㎜/l turn) for 10 days in case Ⅱ. The consolidation period was about 8 weeks in each case. Thereafter, 6 titanium threaded implants(Branemark, Restore) were simultaneously installed with removal of distractor. The implants were tested clinically and radiographically. Results : Amounts of acquired alveolar bone were 8 ㎜ in case Ⅰ and 6 ㎜ in case Ⅱ respectively, with the increased width of the ridge crests and soft tissue expansion. Dental implants installated on the augmented alveolar ridges in 8 weeks after distrction were confirmed as in good osseointegration and in good function without any complications. Conclusion : Intraoral distraction osteogenesis can be a good option for alveolar ridge augmentation of the severely atrophied ridges and soft-tissue defects. However, for the better vector control of distracting segments and for anterior esthetics, customized distraction devices could be considered later.

      • 통영시와 양산시의 강우시 합류식 하수관거 월류수(CSOs)에 관한 비교연구

        김한석,정병길,정유진,박광현,성낙창 東亞大學校 附設 環境問題硏究所 2004 硏究報告 Vol.26 No.-

        The Objective of this study was conducted to investigate the comparison of combined sewer overflows(CSOs) characteristics for rainy season in Tongyoung and Yangsan city. Two sites for the analysis of CSOs were chosen each in the city of Tongyoung, a coastal area, and in the city of Yangsan, an inland area. The analysis of water quantity on CSOs was conducted with Flo-Tote(Ⅱ) and SIGMA 920. For analysis parameters, BOD_(5), COD_(Cг), TSS, T-P, and T-N were analyzed 12 times in a day. In case of Tongyoung, the pollution load of TSS was noticeable since its large permeability coefficient created by unpaved roads and these results caused in the large inflow of earth and sand or solid materials into combined sewers in the event of precipitation.

      • KCI등재
      • KCI등재후보

        Heparin Binding Epidermal Growth Factor가 인간 방광근육의 비대 / 비후에 미치는 영향

        김한석,이상돈,최성 대한배뇨장애요실금학회 2008 International Neurourology Journal Vol.12 No.2

        Puropose: The bladder outlet obstruction (BOO) causes a bladder hypertrophy and/or hyperplasia with time. Heparin binding epidermal growth factor like growth factor (HB-EGF) is a potent mitogen for bladder smooth muscle cell (BMSC), causing significant cellular hypertrophy. Few studies have evaluated the effect of HB-EGF on bladder hypertrophy or hyperplasia. We studied to evaluated the effect of HB-EGF on the hypertrophy or hyperplasia of human BSMC and fibroblast. Material and methods: To evaluate the change of expression of HB-EGF mRNA of human BMSC under a constant stimuli of 40cm-H20 pressure during 0, 1, 3 and 5 hours, RT-PCR was perfromed. The human BMSC and bladder fibroblasts with the addition of the recombinant HB-EGF 25ng/ml were performed 3H-thymidine and 3H-leucine incorporation assay for DNA and protein production, respectively. Results: The expression of HB-EGF mRNA in BMSC under a constant stimuli of 40cm-H20 pressure was up-regulated with time (p<0.05). The optimal concentration of HB-EGF was 25ng/ml. The 3H-Lecine and 3H-thymidine activity in both human BSMC and fibroblast were significantly increased in addition of 25ng/ml of HB-EGF (p<0.05 and p<0.05, respectively). Conclusions: Constant hydrostatic pressure induces the expression of HB-EGF in human BSMC. Subsequently HB-EGF induces hypertrophy and hyperplasia of human BSMC and fibroblast in vitro. Our data support that HB-EGF is one of relevant BOO-induced growth factors. (J Korean Continence Soc 2008;12:169-77)

      • 통영시와 양산시의 건기시 합류식 하수관거 월류수(CSOs)에 관한 비교연구

        김한석,정병길,성낙창 東亞大學校建設技術硏究所 2004 硏究論文集 Vol.28 No.1

        Two analysis sites were set up each for this study in the city of Tongyoung, which has the characteristics of a coastal area, and in the city of Yangsan, which has the characteristics of an inland area, water quantity, and water quality and analysis of initial rainfall pollution level on Combined Sewer Overflows(CSOs) were performed. Based on the findings of these analyses. comparing and predicting the characteristics of effluent considering rainfall intensity using SWMM modeling is the purpose of this study. Following the compilation and analysis of data. the selection of analysis sites for preliminary samples, and the confirmation and examination of the sites for the field study, two sites for the analysis of CSOs were chosen each in the city of Tongyoung, a coastal area, and in the city of Yangsan, an inland area. The analysis of water quantity on CSOs was conducted with Flo-Tote(Ⅱ). For analysis parameters. BOD_(5), COD_(Cr), TSS, T-P, and T-N were analyzed 12 times a day. The results of SWMM modeling based on the amount of rainfall of Tongyoung and Yangsan revealed a little difference between measured value and predicted values, but the difference was modest in terms of volume. However, continuous studies on major coefficients and variables considering the amount of rainfall and local characteristics are required for more exact conclusion.

      • 신세포암에서 기원한 부신전위에 대한 부신적출술의 치료적 유용성

        김한석,김택상,류현열 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.1

        Background : Adrenalectomy has traditionally been included as a component of the radical nephrectomy. However, its role remains controversial. The incidence and characteristics of ipsilateral adrenal involvement in patients with renal cell carcinoma(RCC) were assessed to determine whether ipsilateral adrenalectomy during radical nephrectomy is essential. Materials and Methods : Between March 1985 and March 2005, the medical records of 230 patients, who underwent a radical nephrectomy were reviewed retrospectively. All patients had unilateral RCC, and radical nephrectomies were performed either with(adrenalectomy group, 102 patients) or without(adrenal sparing group, 128 patients) an ipsilateral adrenalectomy. The medical records, pathologic specimens, preoperative and post operative CT findings were reviewed. The survival rate was assessed using the Kaplan-Meier method. In conjuntion with a univariate analysis, a multivariate analysis was performed, using a Cox regression analysis, to determine the independent prognostic factors. Results : The ages of the adrenalectomy and adrenal sparing groups ranged from 5 to 79(mean age : 54.3 years) and 2 to 82 years(mean age : 53.6 years) respectively. there was no significant differences between the two groups in terms of age, sex, location, clinical stages and tumor grade. Of the 102 patients with ipsilateral adrenalectomy, 7 (6.9%) patients had adrenal involvement, all of which had advanced stage (cT3 or greater) in preoperative CT scan. In 5 of these 7 patients, adrenal involvement was documented in preoperative CT, but in the other 2, there were no adrenal abnormalities in CT scan. In 3-year survival rates of adrenalectomy group and adrenal sparing group were 76.6% and 75.7%, respectively, and the 5-year survival rates were 72.6% and 72.2%, respectively (p=0.952). In adrenalectomy group, high T stage and adrenal involvement were revealed as prognostic factors by the multivariate statistical analysis (p=0.005, and 0.000 respectively) Conclusions : A routine ipsilateral adrenalectomy during a radical nephrectomy may not be needed, particulary in localized early stage renal cell carcinoma (T1~2). Ipsilateral adrenalectomy during a radical nephrectomy does not improve the prognosis of patients with renal cell carcinomas.

      • 정신분열병 및 기타 정신증 환자에서 나타난 박해자의 시대에 따른 변화

        김한석,박상학,김상훈,황걸,김학렬 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

        Objective: This study aimed to investigate changes of the persecutors in patients with schizophrenia and other psychotic disorders with the vicissitude of the times in Korea. Methods: Data were collected from 15 papers (total: 2,944 persons, Male: 1,677, Female: 1,267) about persecutors observed in schizophrenia and other psychotic disorder patients with persecutorU' delusion which were published between 1962 and 2004 in Korea. Persecutors were classified into 7 Classes: CIass 1 (unspecified or all person), Class 2 (family, relatives), Class 3 (neighbors, friends, fellows), Class 4 (the communists, the Red-army, spy), Class 5 (secret agents, Police, political character or army), Class 6 (impersonal), Class 7 (others). 15 published papers were classified into 3 groups (A,B,C) by times: group A (1945-1960, Pros and cons of democracy and communism), group B (1961-1992, Suppression of democracy and anti-communist policy by military), group C (1993-2004, Democracy by civilian). The authors investigated the total frequency (%), tendency of changes, difference of frequency of 7 classes in each group of times (A,B,C). Results: 1) Class 1 was the most common persecutor (25.35%) in all of 3 groups (A,B,C). 2) Class 2 and 6 showed the highest tendency of increase and Class 4 showed the highest tendency of decrease. 3) In comparison of the times (A,B,C), Class 4 in A, Class 5 in B, Class 6 in C showed higher frequency. 4) In comparison between capital region and country, CIass 1 and 5 in capital region and Class 6 in country showed higher frequency. 5) In comparison by sex, Class 3 in male and Class 2 in female showed higher increasing tendency. Class 4 and 5 in male showed more decreasing tendency than female in C times, Conclusion: Persecutors of persecutory delusion in patients with schizophrenia and other psychotic disorders vary by sex and residential region, and have been changing with the vicissitude of the times.

      • KCI등재

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