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      • KCI등재

        Myocardial T1 and T2 Mapping: Techniques and Clinical Applications

        김판기,홍유진,임동진,서영주,박철환,김진영,장수연,이혜정,허진,김영진,최병욱 대한영상의학회 2017 Korean Journal of Radiology Vol.18 No.1

        Cardiac magnetic resonance (CMR) imaging is widely used in various medical fields related to cardiovascular diseases. Rapid technological innovations in magnetic resonance imaging in recent times have resulted in the development of new techniques for CMR imaging. T1 and T2 image mapping sequences enable the direct quantification of T1, T2, and extracellular volume fraction (ECV) values of the myocardium, leading to the progressive integration of these sequences into routine CMR settings. Currently, T1, T2, and ECV values are being recognized as not only robust biomarkers for diagnosis of cardiomyopathies, but also predictive factors for treatment monitoring and prognosis. In this study, we have reviewed various T1 and T2 mapping sequence techniques and their clinical applications.

      • 교내 구내식당 음용수와 복도 정수기수의 미생물오염 조사

        김판기,최성부 용인대학교 자연과학연구소 2002 自然科學硏究所論文誌 Vol.7 No.1

        This study was carried out to determine the adequacy of drinking water in school cafeteria and purified water for portability. In this study, total bacteria and total coliform were included. For this study, three places of cafeteria (NSC, SBC, DBC) and 3 sites of purified water were used and collected two times from each places during September 30 to November 1. The following results were obtained ; In school cafeteria NSC, SBC, DBC, the total bacterial count were 143 - 234 CFU/ml. Total bacterial count were some higher compared with guideline of Ministry of Environment's Potable Water Quality Standared. The total coliform were not deteted except one place, DBC. In portable water site, the total bacterial count were 41 - 316 CFU/ml, two places water over the Standard. The total coliform were not detected except one place, NSI, The contamination in drinking water at school were varied, it is important for water hygiene to do regular management in drinking water suppliers.

      • KCI우수등재
      • 구루메 急性 毒性 實驗

        金判起 용인대학교 자연과학연구소 1997 自然科學硏究所論文誌 Vol.2 No.2

        미강 발효추출물(구루메)의 경구투여에 의한 급성독성을 평가하기 위하여 시험물질을 2.5, 5.0, 10.0 ml/kg/day의 용량으로 ICR계 암.수 마우스에 1회 경구투여 하였다. 투여 후 사망동물, 일반증상 및 체중변화를 관찰하였으며, 부검 후 육안적 부검소견을 실시하여 얻어진 결과는 다음과 같다. 대조군 및 시험물질 투여군에서 전 투여기간에 걸쳐 투여물질에 의한 사망동물은 없었으며, 일반증상은 투여 후 별다른 이상이 관찰되지 않았다. 시험물질 투여 후 체중을 측정한 결과 중용량군과 고용량군의 수컷에서 투여 2일 후에 일시적으로 체중이 감소하는 경향을 나타냈으며, 특히 고용량군에서는 Day 0의 체중에 비하여 투여 2일의 체중은 유의한 감소를(p<0.05) 보였다. 그런, 투여 6일 이후의 수컷체중은 유의한 변화가 인정되지 않았다. 암컷체중에서는 유의한 변화가 인정되지 않았다. 육안적해부소견은 중용량군 수컷중 1례에서 대장일부에 미약한 염증성 변화가 관찰되었으나 시험물질에 의한 영향으로 인정되지 않았으며 기타 다른 시험군에서는 특이할 만한 육안적 소견이 관찰되지 않았다. 이상의 결과를 종합하여 볼 때, 본 실험조건에서 미강발효추출물(구루메)에 대한 LD50은 10ml/kg/day 이상으로 추정되었다. Glumate is one of the fermented chaff solution which main component is glutamate. We investigated the acute toxicity of Glumate were examined using SPF ICR mouse for 2 weeks. The Glumate was administered by gastric intubation, 2.5ml/kg, 5.0ml/kg, 10ml/kg body weight. The results were as follows : 1. There were no adverse effects on the clinical observation and no dead mouse due to the effects of administered materials. 2. There were some body weight change in the male high dose group on the 2 days after administration, but it was recovered 6 days after administration. 3. Pathological changes of the brain, liver heart, spleen, kidney, stomach, lung, testis, ovary, uterus, intestine and thymus were not observed in the treated mouse. From the obove results, the Glumate has no acute toxicity upto the 10mg/kg of oral dose, and the LD50 of Glumate is estimated higher than 10ml/kg of oral dose.

      • KCI등재

        독립된 거래객체로서의 건물에 관한 법률문제 연구

        김판기 한양법학회 2017 漢陽法學 Vol.28 No.4

        Land and buildings are recognized as objects of independent transactions in the domain of property law. In the case of buildings, there are several legal issues depending on the state of the building. For example, Various legal issues may arise as follows: What is the scope of the buildings that are subject to property registration?, Whose ownership is vested in building buildings?, Can a building under construction be registered? and so on. However, in the current law, there is not regulation about the concept of building. We only must satisfy the required conditions to be acknowledged as a building which becomes a target of the real-estate registration by judicial precedents and the regulation concerned with registration : ① a building has to be got settled firmly at the land, ② a building has to be divided in structure(for example : a roof, the four walls of a building and so on), ③ a building may be independently used. There are various demands recently for buildings. And buildings which have various uses and structures have appeared one after another. So, the concept of a simpler building in the past is increasingly difficult to solve. The definition of concept by working guidelines or interpretation is a consistent response to the legislative and legislative issues relating to the building. Therefore, we need to clarify the concept of the building which is the separated object of transactions. In this study, I would review analysis the required conditions to be acknowledged as a building in Korea and Japan(real-estate system of Japan is very similar to real-estate system of Korea). On the basis of review and analysis, I would give careful consideration to concept formulation about these buildings. And then, I would offer a legislative bill on definition of the building which is the separated object of transactions as follows: [Civil Act] Article 99(Immovables and Movables) ① Land and things firmly affixed thereto shall be immovables. All things other than immovables shall be movables. ② In the preceding paragraph, things firmly affixed thereto shall be building that a piece of work that has been settled on land with independent property values and uses and all things other than building.

      • KCI등재후보

        일조방해로 인한 손해배상채권에 있어서 소멸시효의 기산점 - 대법원 2008. 4. 17. 선고, 2006다35865 전원합의체 판결 -

        김판기 대한변호사협회 2009 人權과 正義 : 大韓辯護士協會誌 Vol.- No.389

        The interruption of light means disadvantages arising from being blocked from a direct ray of light, and if the degree of that interruption exceeds the generally accepted tolerance limits in light of social norms, then interruption of light can be viewed as an unlawful and harmful act as a matter of private law. The property losses such as a price decline of real estate caused by an unlawful act of interruption of light occur at one time on which building has been completed unless there are special circumstances. However, mental damage suffered by the residents of building invaded, as a result of getting living environments deteriorated such as blocking of a direct ray of lights due to interrupted light, shall be considered as damages occurring everyday continuously as long as the invading building continues to exist. But Supreme Court made an error by deciding a case as below - prescription in respect of right to claim for damages resulting from interruption of light provided by article 766 (1) of the Civil Code starts to run, in principle, from the date when buildings, etc., which are being unlawfully constructed, have been completed or the construction of its outside frame has been completed because shadow caused by the act of constructing does not increase any more and a land owner can expect property losses or mental damage, etc. as a result of interruption of light occurring currently or in the future. So, in this study I would consider and point out an error about this decision. 일조권은 사람이 건강하고 쾌적한 생활을 누릴 수 있는 환경요소 중 태양의 직사광선을 받을 권리를 의미하는 것으로, 인접 토지상의 건물 등에 의하여 태양의 광선이 차단되는 불이익을 받는 경우 그 보호를 요구할 수 있다. 일반적으로 일조권의 침해로 발생하는 손해는 부동산의 시세 하락 등의 재산상 손해, 이러한 재산상 손해로 인하여 겪게 되는 정신적 손해, 일조방해로 인하여 직사광선이 차단되는 등 생활환경의 악화로 인해 거주자가 입게 되는 정신적 손해 등 서로 성질이 다른 다양한 것들이다. 그러나 대상판결은 불법행위가 계속적으로 행하여지는 결과 손해도 역시 계속적으로 발생하는 경우와는 달리 손해가 계속 발생하더라도 가해행위 자체가 이미 종결되어 이를 제거할 수 없는 경우에는 그 계속적 손해에 대한 배상채권은 불법행위시에 전범위에서 일률적으로 그 소멸시효가 진행된다고 보고, 대상판결의 사안과 같은 아파트의 건축으로 인한 일조권침해는 건축행위의 종료와 함께 종결되고, 다만 그 손해만이 계속하여 발생한다고 봄이 상당하므로 건축을 마치고 준공검사를 받은 때에 특별한 사정이 없는 한, 그 소멸시효가 진행된다고 판시하여, 일조권 침해와 같은 계속적 불법행위에 의한 손해배상청구권의 소멸시효 기산점의 해석에 대한 문제점을 드러내고 있다고 생각한다. 이에 본 논문에서는 일조권의 개념과 법적성질에 대하여 살펴보고 이를 토대로 일조방해에 의해 발생되는 손해를 어떻게 구분할 수 있는지를 고찰하였다. 그리고 일조권 침해에 따른 각각의 손해에 대하여 그 손해배상청구권의 기산점을 어떻게 결정할 것인지에 대해 국내외 학설과 판례를 중심으로 고찰하여 대상판결의 사안을 재검토해 보기로 한다.

      • 랫드 수유기에 폭로된 Bisphenol A의 영향

        김판기,류재흥 龍仁大學校 2003 용인대학교 논문집 Vol.21 No.-

        Bisphenol A used to the production of epoxy resins and polycarbonate plsastics. This study was carried out investigate the effects of bisphenol A treatment on during lactation period of the F1 and dams. Sprague-Dawley female rat of 10 weeks old were used. The dose level were control, low (2 ㎍/㎏), medium (200㎍/㎏), middle high (2,000㎍/㎏), high (20,000㎍/㎏). The rats were mated with male rats on a 2:1 ratio basis. Repeated doses of bisphenol A were treatment on female rats for 21 days after parturiton. Dams adn offsprings were sacrificed after lactation period. The result as follows. 1. Bisphenl A increased the liver, spleen, kidney weight of female offspring, but not depending on the dose. Male offspring, also increased liver, spleen kidney weight and testis, prostate gland weight, but not depending on the dose. 2. Number of 3.2.2 dams show premated estrus cycle on medium (200/㎏), mid high (2,000㎍/㎏), high (20,000㎍/㎏) treated with bisphenol A 3.HPLC (High Performance Liquid Chromatography) analysis detected 21.2% of average bispheno A equivalent to treatment dose in serum of dams, and also found in offspring serums. The results indicate that the estrus was induced during lactation period of dams by bisphenol A, also reached offspring blood through the dams breast milk.

      • 물고기 배자를 이용한 acetaminophen의 내분비교란성 탐색

        김판기 용인대학교 자연과학연구소 2011 自然科學硏究所論文誌 Vol.16 No.1

        Acetaminophen (AA) is a commonly used analgesic and antipyretic drug that is present in >850 over-the-counter and prescription formulas. AA is taken acutely, as well as chronically, by millions of adults and children. Metabolism of AA, primarily in the liver by mixed function oxidases, can result in the production of a highly reactive metabolite, N-acetyl-p-benzoquinoneimine (NAPQI). At high doses acetaminophen elicits well-characterized hepatotoxic effects due to the production of NAPQI, which are exacerbated by ethanol consumption. Several in vivo studies suggest AA may alter some hormone-regulated processes in reproductive tissues. AA reduced the reproductive capacity, testicular weight, and spermatogenesis of mice and reduced E2-induced uterine peroxidase activity and nuclear progesterone receptor protein in immature mice. In humans, AA had no significant effect on breast cancer risk but reduced the risk of ovarian cancer and significantly lowered basal levels of gonadotropin and estradiol. However, AA did not increase uterine wet weight in mice or rats, and did not affect E2-induced increases in rodent uterus weight. In this study, toxicogenomics used to find out the outcome of this modulating in fish embryo. The results could not found out the exact findings of this effects, but you can use this protocols using fish embryo and some markers in this purpose.

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