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To investigate the correlation of the vascular spiders with variceal bleeding in patients with liver cirrhosis, we performed esophagoscopy to determine the pretence and the size of the varices and a concomitant skin examination far assessment of cutaneous vascular spiders in 40 patients with liver cirrhosis who admitted to Pusan National University Hospital from Aug. 1988 to Aug. 1989 The results were as follows 1) The ratio of males to females was 4:1 in bleeder, and 7:3 in nonbleeders and the age group was most preveatent in 6th decades (30.0%), and 5th decades (35.0%). 2) The incidence of vascular spiders was 30/40 (75%) and that of varices was 35/40 (87.5%), variceal bleeders had a higher average unmber of spiders compared with those who hart never bled (90%, 60%, P$lt;0.005). 3) The incidence of vascular spiders according to the etiology was 17/26 (65%) in postnecrotics, 6/6 (100%) in alcoholics, So in alcoholic cirrhosis, the incidence of vascular spider and variceal bleeding was higher (p$lt;0.005). 4) The incidnce of vascular spider and variceal bleeding according to the child's classificattati waa more higher in C group (85.0%, 69.2%) than A (60.0%. 50.0%) and B (76%, 35%) (p$lt;0.05) group. 5) Twelves of 40 patients (30%) with large spiders ($gt;15㎜), 14 of 40 patients (32.5%) with numerous spiders ($gt; 10) had high incidence of varices and the patients with multiple a stypical lesion had high incidence of varices also.
The survery on blood pressure of a part workmen(1.264 persons) from February 1 to May 30 in 1997 as shown the types of following as the average blood pressure, the possible proportion in Which will be striken with blood pressure, and the types of high blood pressure. 1. Average Blood Pressure The higher is age, the more is the average blood pressure increased in the constractor and expender blood pressure, and analyzed by age and sex the men in twenties and thirties were in creased greatly, but in forties were shown little difference. 2. The prevalence rate of hypertension in which will be striken with High Blood Pressure. In the prevalence rate of hypertension in which will be striken with high blood pressure is shown in creasingly up to 14.8 percent, and in age 11.8 percent in thirties, 21.4 in forties, 39.7 in fifties. That is, the higher is age, the more is The prevalence rate of hypertension increased. In the proportion of fat, 2.9 percent is shown in no less than zero percent, 18.3 percent in from zere to 19 percent, and 23.7 percent in over 20 percent. That is, blood pressure is increased in proportion to the fat proportion. 3. Types of High Blood Pressure The entire types of blood pressure are shown as follows: Diastolic alone is shown 65.8 percent in the expender blood pressure, Diastolic and Systolic 31.5 percent in the expender and constractor blood pressure, and Systolic alone 2.7 percent in the constroctor blood pressure.
It is known that severe infestation of polychaetes with abalone shells can cause mortality and affect productivity. In order to obtain accurate data on polychaete infestations, we surveyed the infection rate of polychaetes in the abalone, Haliotis discus hannai cage farms located in Wando area. The survey included changes in infestation rates for three years, monthly and seasonal changes in infestation rates and infestation rates in the spawning field. The range of infestation rate of polychaetes against abalone for 3 years was 23.8-52.8%. In general, infestation rate increased rapidly around high temperature (around August) and peaked in autumn. The mean infestation rate of the polychaetes of the onshore farms producing abalone was 5.4%. Therefore, the rate of polydorides infestation in abalone farms in Wando-gun increased during the period of rising water temperature, and it is considered that the infestations that occur during the production of young shell may be affected.
1999년 10월에서 11월 사이에 남해안 일대의 홍민어 종묘 생산장에서 20~30열령의 치어가 척추만곡 및 이상유영을 하며 대량 폐사하였다. 병어는 특이 외부 증상이 없었고, 높은 누적폐사량이 바이러스 질병으로 의심되어, 조직학적 및 분자생물학적인 검사를 행하여 폐사원인을 확인하였다. 폐사개체의 조직을 H-E 염색하여 관찰한 결과 뇌와 안구의 신경세포에서 공포와 괴사가 관찰되었고, 전자현미경 관찰에서는 안구와 뇌에서 바이러스 입자가 관찰되었다. RT-PCR 결과에서는 ≒426 bp의 DNA 단편을 확인할 수 있었다. 이러한 결과로 홍민어에서 발생한 대량폐사는 바이러스성 신경괴사증(VNN)으로 진단되었다. Mass mortalities occurred among red drum lavae, 20 to 30 days old, culturing at hatcheries on southern costal area. No specific external signs were observed except abnormal swimming and spinal deformity. It was, however, suspected as a viral etiology due to high mass mortalities so that histopathological and molecular biological study was performed to evaluate the agent. Both vacuoles and necrosis were observed on nerve cells of brain and eye by H-E staining, and viral particles were observed on electronmicroscopic examination. On the other hand, DNA fragment, approximately 426 bps, was amplified with RT-PCR. The above results were able to diagnosis the etiological agent of mass moralities in red drum larvae as VNN(viral nervous necrosis)virus.
The effects of dietary yeast β-glucan administration on growth, nonspecific immune responses, serum lysozyme, skin mucous lysozyme, NBT (nitroblue tetrazolium) reduction by phagocytes, and disease resistance against Edwardsiella tarda in Japanese eel, Anguilla japonica were evaluated. Fish were fed the diets supplemented with 0%, 0.1% and 0.5% of yeast β-glucan to a commercial diet for 6 weeks. The body weight gain from the fish fed on the 0.5% supplemented diet for 6 weeks was significantly higher than the control. Both serum and skin mucous lysozyme were significantly higher in the all experimental groups except 2 weeks of 0.5% group. The bactericidal activity of serum was slightly increased at 6 weeks. Also, The intracellular superoxide anion production of kidney phagocytes was significantly higher in the all experimental groups. The diet supplemented with 0.1% were also found to raise the relative percent survival (RPS) of Japanese eel after an artificial challenge with 1×107 cells of Edwardsiella tarda per fish. The results suggested the potential of yeast β-glucan to activate some innate immune responses and to improve the growth in Japanese eel.