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흰쥐 자궁근의 자발적 수축과 칼륨 경축에 미치는 칼숨의 효과
김의용 全北大學校 學徒護國團 1981 全國大學生學術硏究發表論文集 Vol.6 No.-
The influences of Ca^++ upon the spontaneous contraction and the contracture induced by 60mM K^+ - Tyrode solution were studied in isolated uterine muscle. Longitudinal muscle' strips were prepared from the rat uteri in estrous stage. All experiments were performed in tris-buffered Tyrode solution which was aerated with 100% O_2 and Kept at 35℃. The results obtained were as follows; 1. In the uterine strips contracting spontaneously, both the amplitude of peak tension and the area of contraction curve increased dose-dependently in the range of 0.5 - 8mM Ca^++. The frequency of contraction increased as the concentration of Ca^++ increased to 2mM, but above this concentration the frequency decreased. In Ca^++ -free media, however, contraction was not developed. The tension of uterine strips increased in proportion to an increase of K^+ concentration in media and reached peak value at the concentration of 100mM K^+. In the contracture induced by 60mM K-Tyrode solution, the developed tenstion increased dose-dependently as the concentration of external Ca^++ increased to 8mM and even in the absence of external Ca^++, k-contracture appeared, which was not sustained. The above results suggest that exterenal calciumion is essential for spontaneous uterine contraction, and the amplitude of peak tension in spontaneous contraction is related to transmembrane Ca^++influx.
김의용 인제대학교 1989 仁濟醫學 Vol.10 No.2
토끼 심장의 동발결절 세포의 막전압이 심장근의 다른 세포에 비해 작은 이유 중의 하나는 Na과 K의 세포막 투과성 비율(PNa/PK=α)이 큰 것이 한 원인으로 생각된다. Membrane potential of cells in the isolated SA node of rabbit was measured by conventional glass microelectrode and investigated the effect of [K+]o variation in control, 20mM Na, Mn++ -containing 20 mM Na and Acetylcholine-containing Tyrode solution. All experiments were performed in tris-buffered Tyrode solution which was aerated with 100% O2 and kept at 37℃. The results obtained were as follows : 1.The membrane potential exposed to normal Tyrode solution containing 3 mM K+ was about -40mV. At extracellular K+ concentration from 1 to 30mM the membrane potential was reasonably well described by Goldman-Hodgkin-Katz equation on the assumption that [K+]i was 150mM and that the ratio of membrane permeability coefficient for Na+ and K+, PNa/PK (α) was 0.25. 2.In the presence of 5×10-6M Acetylcholine, the membrane potential at [K+]o levels from 1 to 30mN were fitted with the predicted value on the assumption that PNa/PK (α) was 0.09. 3.In 20mM Na-Tyrode solution replaced by equimolar Tris, the membrane potential was hyperpolarized and showed slightly deviated to depolarized direction compared to the predicted value by Goldman-Hodgkin-Katz equation. 4.In Mn++ -containing 20mM Na-Tyrode solution by equimolar Tris, the membrane potential was also hyperpolarized but showed the correspondence with the predicted value by Goldman-Hodgkin-Katz equation compared with the case of 20mM Na-Tyrode solution. From above all the results, it is suggested that low membrane potential of SA node reflects not a low [K+]i but rather a relatively high ratio PNa/PK (α), of about 0.25, that is, Na influx contribute to the membrane potential.
이탈리아 건축가 까를로 아이모니노의 건축유형학과 도시형태학에 관한 연구
김의용 동명정보대학교 2000 東明情報大學校論文集 Vol.3 No.-
The study of architectural typology for redefining essence of architecture involves the problem of architectural form, the relations of architecture and city, the problem of precedent, and the interpretation of classic. In this study is historically researched the process of theory of architectural typology in Italian Rationalism and is analyzed the works applied this theory of an Italian architect. The viewpoint of Carlo Aymonino who is worked among the new-rationalist architects in the School of Venice, relates the architectural typology to city. Carlo Aymonino's architecture tried to revive the historical continuity thought the architectural application of urban space make it possible the various transformation of architectural typology and urban morphology.
김의용 인제대학교 1988 仁濟醫學 Vol.9 No.2
세포외액의 칼슘이 자궁근의 자발적 수축에 필수적이며 자발적 수축에서의 장력의 크기는 세포외액으로부터의 칼슘 유입에 의존한다고 생각된다. The influences of Ca++ on the contraction and the contracture induced by 60mM K-Tyrode solution were studied in isolated uterine muscle. Longitudinal muscle strips were prepared from the uteri in estrous stage. All experments were performed in tris-buffered Tyrode solution which was aerated with 100% O2 and kept at 35℃. The results obtained were as follows ; 1.In the uterine strips contacting spontaneously both the amplitude of peak tension and the area of contraction curve increased dose-dependently in the range of 0.5-8mM Ca++. The frequency of contraction increased as the concentration of Ca++ increased to 2mM, but above this concentration the frequency decreased. In Ca++ -free media, however, contraction was not developed. 2.The tension of uterine strips increased in promotion to an increase of K+ concentration in media and reached peak value at the concentration of 100wM K+. 3.In the contracture induced by 60mM K-Tyrode solution, the developed tension increased dose-dependently as the concentration of external Ca++ increased to 8mM and even in the absence of external Ca++, K-contracture appeared, which was not sustained. The above results suggest that external calcium ion is essential for spontaneous uterine contraction, and the amplitude of peak tendon in spontaneous contraction is related to transmembrane Ca++ influx.
1945년부터 1962년까지 부산 가톨릭 성당건축의 성격에 관한 연구 - 배치형식과 건축양식을 중심으로 -
김의용 대한건축학회지회연합회 2008 대한건축학회연합논문집 Vol.10 No.1
The purpose of this study is to clarify the characteristics of the catholic cathedral architecture in Busan. Especially, this study is focused on architectural style and the site planning of the catholic architecture effected by social and economic situation from 8.15 liberation to 1962. The catholic architecture style in Busan of this periods is separated in four type : the revival style, eclecticism style, functional style and modern style. These styles was effected by the social-economic situation and growing attention of catholic in Korea.
김의용 동명정보대학교 2002 건축도시연구소 저널 Vol.1 No.-
The study on architectural typology for redefining essence of architecture involves the problem of architectural form, the relations of architecture and city, the problem of precedent, and the interpretation of classic. In this study if historically reserched the process of theory of architectural typology in Italian Rationalism and is analyzed the tendence of theory of architects. Especially, this study is focused on the diverse approach to the concept of architectural type of italian architects who tried to introduce a historical continuity to the process of project. In conclusion of this study is looked over the practical application of theory of architectural typology and was defined the relation between architecture, urban, history, and context.