유체 거동에 따른 여과집진설비의 탈진향상에 관한 연구

김유재,윤도영,박효균,고재욱 한국공업화학회 2023 한국공업화학회 연구논문 초록집 Vol.2023 No.0

기능성게임 평가요소와 군 시뮬레이터 평가요소 비교분석에 관한 연구

김유재,김정윤 차세대컨버전스정보서비스학회 2018 차세대컨버전스정보서비스기술논문지 Vol.7 No.1

There is various training programs are being conducted to improve combat strength in the military. Among them, Virtual, Constructive and Live simulation using Defense M & S are one of the representative education and training systems, and this can be regarded as a category of serious games. In this study, we examine the training systems that are currently operating in the military with the classification criteria presented in the serious games, and examine the functionality of the military serious games by applying the evaluation elements of the serious games to the military simulators. For further research, we will collect objective data from the military training system and prepare appropriate evaluation factors and standards for military serious games. 군에서는 전투력을 향상시키기 위해 각종 교육훈련을 진행하고 있다. 그중 국방 M&S를 활용한 가상(Virtual) 시뮬레이션, 구성(Constructive) 시뮬레이션, 실(Live) 시뮬레이션이 대표적인 교육훈련체계 중 하나이고 이는 기능성 게임의 범주에 해당한다고 할 수 있다. 본 연구에서는 기능성게임에서 제시한 분류 기준으로 현재 군에서 운용중인 훈련체계들을 살펴보고, 기능성게임의 평가요소를 군 시뮬레이터에 적용해 봄으로써 군 기능성게임의 기능성을 살펴보고, 부족한 재미요소를 확인해 보고자 한다. 향후 연구로는 군 훈련체계에서 객관적인 데이터를 수집해 군 기능성게임에 적합한 평가요소와 기준을 마련할 것이다.

사염화탄소(CCl₄)에 의한 간손상 흰쥐의 Trithioformaldehyde의 방어효과(Ⅰ)

김영석,김종배,김천숙,권준택,최규홍,이종화,조병헌,차영덕,김유재 순천향대학교 1989 논문집 Vol.12 No.3

Trithioformaldehyde(TTFA) is a cyclic aliphatic compound containing three sulfur atoms. TTFA was synthetized from formalin and hydrogen sulfide in our Lab.. Pharmacological effects of TTFA were clarified in our Lab.: antifungal effects, and radiation protective effect in mice. In this experiment, the protective effect of TTFA on CCl₄ induced hepatotoxicity in rats was evaluated histopathologically. Groups consist of net control, administered with CCl₄ only and TTFA pretreatment. CCl₄(1ml/kg) was given i.p. as a 50%(V / V) solution in olive oil. TTFA(300mg/kg) suspended in 5% arabia gum was given i.p. 24hrs and 20min before CCl₄ administration. The rats that received CCl₄ were sacrificed 24hrs later. In pathological finding, massive fatty change with necrosis in the centrilobular area is found in CCl₄ only treated group. In TTFA pretreated group, a slightly necrotic change in the midzone is noted. Remarkable reductions in hepatic glycogen were observed in CCl₄ only administration. TTFA prevented them from disappearing. These results show that TTFA has a significantly protective effects aganinst CCl₄ induced hepatotoxicity.

연령적 추이에 대한 폐기능력에 관한 연구

심동원,김유재 순천향대학교 1991 논문집 Vol.14 No.2

In order to evaluate the age-related changes of pulmonary fuction, the vital capacities, tidal volumes, expiratory reserve volumn and respiratory rates were meansured in 1592 normal men and women aged between 10 to 49 years. The volunteers were composed of 355 boys and 402 girls aged between 10 and 18 years, 490 adults men and 289 adult women aged between 19 and 29 years, and middle age men in their thirties and fourties. The degrees of concomitant rise in lung volumn in accordance with the growth of physical body feature were measered in accordance with the growth of physical body feature were measered in boys and girls and reflections of body status in lung volumns were analyzed for the young adults. The age dependency of the inverse relation between lung volumn and body weight was also cheked of the middle aged men. Results are as follow : 1. During the age of 10 to 18, both the vital capacity and tidal voume increased with the progress of age : 2. The vital capacities and tidal volumes of young adults aged between 19 and 29 years remained constant. 3. The vital capacities and tidal volumes of middle aged men are found to be decrease with the progress of age. However, the decrease of vital capacities are more extensive than volumes. 4. In growth generation(10-18), adolescence(19-29), middle mature age(30-49), by the distinction of sex, the relation between vital capacity, tidal volume and body weight is very large(r >0.57), is indicative of simple regression curre.

CVD 반응기내 기체유동의 균일성 향상에 관한 수치적 연구

김유재(Y-J. Kim),김윤제(Youn J. Kim) 대한기계학회 2004 대한기계학회 춘추학술대회 Vol.2004 No.8

CVD 반응기 내에서의 유동장에 대한 샤워헤드 지름의 영향에 대한 수치적 연구

김유재(You-Jae Kim),김윤제(Youn J. Kim) 대한기계학회 2004 대한기계학회 춘추학술대회 Vol.2004 No.4

Plasma Enhanced Chemical Vapor Deposition (PECVD) process uses unique property of plasma to modify surfaces and to achieve the high deposition rates. In this study, a vertical thermal RF-PECVD (Radio Frequency-PECVD) reactor is modeled to investigate thermal flow and the deposition rates with various shapes of the showerhead. The showerhead in the CVD reactor has the shape of a ring and gases are injected in parallel with the susceptor, which is a rotating disk. In order to achieve the high deposition rates, we have simulated the thermal flow fields in the reactor with several showerhead models. Especially the effects of the number of injection holes and the rotating speed of the susceptor are studied. Using a commercial code, CFDACE, which uses FVM (Finite Volume Method) and SIMPLE algorithm, governing equations have been solved for the pressure, mass-flow rates and temperature distributions in the CVD reactor. With the help of the Nusselt number and Sherwood number, the heat and mass transfers on the susceptor are investigated. In order to characteristics of measure the flatness of the layer, furthermore, the relative growth rate (RGR) is considered.

마우스의 majarine과 tetrahydromajarine의 체온 감소와 실온변화에 대한 6-hydroxydopamine과 5,7-dihydroxytryptamine의 영향

金裕載,趙炳憲 순천향대학교 1987 논문집 Vol.10 No.1

Majarine that was isolated from Berberis koreana Palibin (Berberidaceae) is the isoquinoline alkaloid. Tetrahydromajarine with tertiary amine is obtained by reduction of majarine(quaternary ammonium salt) with sodium borohydride. Authors had investigated its pharmacological action on the central nervous system. We reported that majarine-induced hypothermia was connected with drugs affecting brain monoamine function in mice. In the present study, we made an attempt an attempt to delineate the possible involvement of brain monoamines in majarine and tetrahydromajarine-induced temperature effects. The responses of animals, which were treated with 6-hydroxydopamine(6-OHDA) to deplete brain catechoilamines, and of thoise which were treated with 5,7-야hydroxydopamine(5,7-옷) 새 deplete brain serotonin, to intraperitoneal administration of majarine, tetrahydromajarine and apomorphine were compared with those control animals at 20 and 28C anbient temperature. Either 6-OHDA 100 mg or before majarine, tetrahydromajarine and apomorphine injection in mice. The results were as follows: 1) Majarine, tetrahydromajarine and apomorphine produced dose-related decreases in rectal temperatyure at ambient of 20 and 28C in mice. On responses of mouse rectal temperature to different ambient temperatures, effecyts of majarine, tetrahydromajarine and apomorphine at 20C were more active than those at 28C. 2) The effects of the forms of amajrine derivatives was compared : a tertiary derivative of tetrahydromajarine was less active than a quaternary derivative of majarine on mouse rectal temperature. 3) At ambinent temperature of 20C , majarine and tetrahydromajarine-induced hypothermia were antagonized by 6-hydroxythemia was antagonizded by 6-tetrahydromajarine, but not by 5,7 -tetrahydromajarine. 4) At ambient temperature of 28C, majarine, tetrahydromajarine, but not by 5,7-dihydroxytryptamine. Consequently, we suggest that majarine show simultanneous effects of central and peripheral origin in cpmparison with tetrahydromajarine. The data indicates that majarine, tetrahydromajarine and apomorphine act on dopamine neurons in brain to influence body temperature.

크론병을 동반한 강직척추염에서 발생한 성인형 스틸병 1예

김유재 ( You Jae Kim ),박환성 ( Hwan Sung Park ),김수정 ( Su Jeong Kim ),김성수 ( Sung Soo Kim ),김용길 ( Yong Gil Kim ),이창근 ( Chang Keun Lee ),유빈 ( Bin Yoo ) 대한류마티스학회 2011 대한류마티스학회지 Vol.18 No.2

Adult-onset Still`s disease (AOSD) is an inflammatory disorder of unknown aetiology characterized by a variety of clinical symptoms. AOSD can precede or occur concomitantly with AS and only a few cases of AOSD with AS have been reported. A 21-year-old man presented with spiking fever, sore throat, arthralgia, maculopapular rash, lymphadenopathy, and chronic inflammatory back pain. His laboratory findings showed marked elevations of liver enzyme, C-reactive protein, erythrocyte sedimentatioin rate, ferritin, and sacroiliitis (grade 2), which were the main characteristics of AOSD and AS. Most symptoms except chronic low back pain were improved after treatment with corticosteroid and disease modifying anti-rheumatic drugs. He was then treated with anti- tumor necrosis factor-alpha (anti-TNF-α) agents to control the disease activity of AS and subsequently showed clinical and serological improvement. This is a first case report of AOSD combined with AS in Korea.

Effects of Trithioformaldehyde on the Biosynthesis of Prostaglandin in Vitro, Prostaglandin Production and Leukocyte Migration in Vivo

Kim, Yu-Jae,Park, Young-Hyun,Kim, Jong-Bae,Kim, Chung-Mok,Cha, Young-Deog,Kim, Young-Suk,Cho, Byung-Heon,Kim, Chun-Sook,Lee, Jong-Hwoa 순천향대학교 1987 논문집 Vol.10 No.2

본 실험실에서는 trithioformaldehyde (TTFA)를 합성하여, TTFA의 여러 약리작용을 검색하고 있다. 본 연구에서는 TTFA의 guinea pig lung homogenate에서 prostaglandins의 합성에 미치는 영향과 carrageenin으로 유도된 염증 산출물에서 prostaglandin의 생성과 백혈구 유주에 대한 작용을 관찰하였다. TTFA(up to 1000㎍/ml)는 guinea pig lung homogenate에 의한 prostaglandin의 합성을 유의하게 억제하였으며, 20㎎/㎏에서 carrageenin으로 유도된 염증에서도 prostaglandin의 생성을 53% 정도 억제하였다. 그러나 백혈구 유주는 TTFA에 의해 약간 증가되었다. Aspirin은 vivo에서 prostaglandin의 합성을 억제하나, 염증 삼출물에서 백혈구 유주에 대해서는 거의 영향이 없었다. Dexamethasone은 vitro에서 외인성 arachidonic acid를 기질로 가했을 때는 prostaglandin 합성에 영향이 없었고 carrageenin으로 유도된 염증에서는 prostaglandin의 생성과 백혈구 유주를 억제하였다. 이상의 결과로 trithioformaldehyde(TTFA)는 항염증 작용을 나타내며 이 작용은 cyclooxygenase를 억제하여 항염증 작용을 나타내는 aspirin 유사약물과 유사한 것으로 추정된다. Trithioformaldehyde(TTFA) was synthesized from formalin and hydrogen sulfide in our Lab. The effects of TTFA on the biosynthesis of prostaglandins from arachidonic acid in guinea pig lung, prostaglandin production and leukocyte migration in carrageenin-induced inflammation were investigated. These effects of TTFA were compared with those of aspirin and dexamethasone. TTFA inhibited cyclooxygenase in guinea pig lung homogenate and reduced rostaglandin concentration in inflammatory exudates. TTFA increased slightly leukocyte migration in inflammatory exudates. These effects of TTFA were similar to that of aspirin which inhibited biosynthesis of prostaglandin in vitro and had a relative small effect of leukocyte migration. Dexamethasone, which did not inhibit cyclooxygenase in vitro, had an effect different from that of TTFA on leukocyte migration in inflammatory exudates.

제왕절개술 환자에서 수술전 투여한 ketamine의 혈청 interleukin-6 및 수술후 통증에 대한 효과

김진수,김유재,안기량,김천숙,김일호,한찬수 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

The inflammatory reaction to tissue damage during surgery may induce central sensitization followed by hyperalgesia. Previous studies suggest that central sensitization is related to N-methyl-D-aspartate (NMDA) receptor activation, which can be blocked with NMDA antagonist, ketamine. Thus, we compared the effect of preoperative intravenous and epidural low doses of ketamine with placebo on serum interleukin-6 (IL-6) level and postoperative pain. ASA class I and II women scheduled for C-sections received intravenous ketamine 0.15mg/kg(group 2) or placebo(group 1), or epidural ketamine(0.15 mg/kg) before the operation. IL-6 levels were measured before and during the operation, and 8, 24, and 48 hrs after the operation. Visual Analogue Scales(VAS) and Verbal Ration Scales(VRS) were measured at 8, 24, and 48 hrs after the operation. Serum IL-6 levels at 8, 24, and 48 hrs after the operation were significantly lower in the intravenous ketamine and epidural ketamine groups than in the control group. VAS at 8 hrs and 48 hrs after the operation were significantly lower in the epidural ketamine group. VAS at 8 hrs and 48 hrs after the operation were significantly lower in the epidural ketamine group than in the control and intravenous ketamine groups. In conclusion, in the preoperative intravenous and epidural administration of low doses(0.15mg/kg) of ketamine, both are effective in reducing postoperative IL-6 levels. Epidural Ketamine is more effective than intravenous ketamine in postoperative pain control.