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가미금궤신기환(加味金櫃腎氣丸)의 항암(抗癌) 및 항전이(抗轉移) 효과(效果)에 관(關)한 연구(硏究)
김용태,전영수,김정효,김성훈,Kim, Yong-Tae,Jeon, Young-Soo,Kim, Jung-Hyo,Kim, Sung-Hoon 대한암한의학회 1999 大韓癌韓醫學會誌 Vol.5 No.1
To evaluate the antitumor activity and antimetastatic effects of Kamigumgusingihwan(KGSH) studies have ken done. The results were obtained as follows: 1. KGSH extracts exhibited a weak cytotoxicity against A549, SK-OV-3, B16-F10, and SK-MEL-2 cell lines. But exhibited potent cytotoxicity against P388 cell line in a dose-dependent manner. 2. The concentration inhibiting adhesion of A549, to complex extracellular matrix up to below 30% of control was recognized at $10^{-3}g/ml$ of KGSH 3. KGSH extracts showed a weak inhibitoty effect on DNA topo-isomerase I from calf thymus. 4. The T/C% was 137% in KGSH treated group in S-180 bearing ICR mice. 5. In pulmonary colonization assay, a number of colonies in the lungs were decreased significantly in KGSH treated group as compared with control group. 6. In hematological changes in B16-BL6 injected C57BL/6, numbers of WBC were decreased insignificantly in KGSH treated groups, and also those of platelet were increased insignificantly in KGSH treated groups as compared with control. 7. In CAM assay, KGSH extracts inhibited angiogenesis at $15{\mu}g/egg $concentration significantly as compared with control. Taken together these results, it is strongly demonstrated that KGSH significantly suppressed tumor metastasis by blocking cell adhesion to extracellular matrix. Therefore, KGSH is expected to be clinically a potent antimetastatic drug for the prevention and treatment of cancer.
IPMSM의 철손계수 산정방법에 따른 철손오차 비교 및 분석
김용태(Yong-Tae Kim),김동영(Dong-Young Kim),조규원(Gyu-Won Cho),김규탁(Gyu-Tak Kim) 대한전기학회 2013 대한전기학회 학술대회 논문집 Vol.2013 No.4
본 논문에서는 Epstein Data를 이용한 Steinmetz 방정식의 철손 계수 산정 방법을 제안하였다. 주파수에 의한 함수로 철손 계수를 산정하는 방법은 주파수에 따라 선형적으로 나타나야 하는 히스테리시스 손실 성분이 비선형성을 가지게 되고, 주파수 증가에 따라 이상와전류 손실이 감소하는 양상을 보인다. 따라서 본 논문에서는 앞서 언급한 방법의 문제점을 보완하기위해 철손 계수를 자속밀도에 대한 함수로 정의하고 4가지 근사함수를 사용하여 철손 계수를 산정하여 비교ㆍ분석하였다.
김용태(Yong Tae Kim),김영기(Young ki Kim),최윤봉(Yoon Bong Choi),안옥균(Ok Kyun Ahn),강연준(Yeon June Kang) 한국자동차공학회 2003 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-
A Study to determine the structure-borne noise radiated by a dash panel of a real car is performed by using the finite element method (FEM) and the boundary element method (BEM). The radiation efficiency is used to estimate the structure-borne noise radiated by a dash panel. The stiffening a dash panel changes the radiation efficiency. A proper increasing stiffness can decrease the structure borne noise of a dash panel. Experimental results of radiation efficiency of a dash panel agree with the simulation results.
SOAP 메시지 처리 개선과 NBTM을 사용한 모바일 웹 서버의 성능 향상
김용태(Young-Tae Kim),정윤수(Yoon-Su Jeong),박길철(Gil-Cheol Park),이상호(Sang-Ho Lee) 한국컴퓨터정보학회 2008 韓國컴퓨터情報學會論文誌 Vol.13 No.5
최근의 급속하게 변화하는 모바일 인터넷 환경에서 이전의 웹 서버 성능으로는 사용자의 빈번한 연결 요구에 대해 적절한 대응이 어렵기 때문에 웹 서비스 엔진의 성능 향상이 필요하다. 따라서 본 논문은 웹 서비스의 성능 향상을 위해서 부가적으로 설치하는 톰캣 서블릿 컨테이너와 무관하게 사용자의 접속 요청을 처리하고, SOAP(Simple Object Access Protocol) 메시지 처리 시간을 단축하는 모바일 웹 서비스의 서버 구조를 제안한다. 제안한 웹 서버 구조는 사용자 요구 수신기, 웹 문서 처리기, SOAP 프로토콜 처리기, NBTM(Non-Blocking and Thread Manager) 관리자, 세션 관리자로 구성한다. 제안된 시스템은 표준 웹 서비스 프로토콜을 완전하게 지원하고, 웹2.0의 모바일 웹 서비스 시스템의 통신 오버헤드와 메시지 처리 시간, 서버의 오버헤드를 감소하며, 웹2.0 환경에서 구현 실험을 통한 지연 수행 평가에 의해서 웹2.0 표준 모바일 웹 서비스 시스템과 성능을 비교, 평가하여 성능 향상을 확인하였다. Recently, the mobile Internet is rapidly changing environment in a user s web server performance requires frequent connection is difficult because the proper response is needed to improve the performance of web services engine. Therefore, the goal of this paper is to improve the performance of web services for the installation of additional access to users regardless of tomcat servlet container and process the request and to shorten processing time of SOAP (Simple Object Access Protocol) message of the server structure to offer web mobile services. The web-sever structure is consists of user demand receiver, web document processor, SOAP protocol processor, NBTM(Non-Blocking and Thread Manager) manager, session manager. The system fully supports a standard web-service protocol, reduces the message processing time and communication overhead of mobile web-service system in Web 2.0 and overhead of server, and confirms the improvement of capability by comparing and evaluating Web 2.0 standard mobile web-service system through delaying achievement evaluation by the experiment of realization in Web 2.0 environment.
김영호(Young Ho Kim),윤용범(Yong Bum Yoon),김정룡(Chung Yong Kim),김용태(Yong Tae Kim),김주성(Joo Sung Kim) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.4
N/A The incidence of intrahepatic cholelithiasis is higher in East Asia including Korea, than in the West. There have been several clinical studies on intrahepatic cholelithiasis, but the subjects of those studies were limited to operated patients. In this study we analyzed 263 patients whose intrahepatic duct stones were confirmed not only by operation but also by radiologic studies. Among the patients, the male to female ratio was 1:1.5 and thirty-six percent of the patients had a past medical history of cholecystectomy. Involvement of both intrahepatic ducts was most common (39.5%) and stones were detected more frequently in the left intrahepatic duct (34.6%) than in the right (25.9%). Extrahepatic duct stones were found more frequently in the patients where both lobes were involved than in those with single lobe involvement. Regardless of the presence of acute cholangitis, one or more organisms grew in alniost every bile culture (98%). In the detection of intrahepatic duct stones, the sensitivity of computed tomography or percutaneous transhepatic cholangiography was higher than that of ultrasonography or endoscopic retrograde cholangiopancdeatography. From the above results, we suggest that biliary bacterial infection may play an importent role in the pathophysiology of intrahe- patic duct stones and that bile stasis also may play a considerable role. Further studies on efficient methods to diagnose and evaluate intrahepatic duct stones are needed in the future.
김영호(Young Ho Kim),윤용범(Yong Bum Yoon),김정룡(Chung Yong Kim),박중원(Joong won Park),김용태(Yong Tae Kim) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.1
N/A The clinical characteristics of 53 patients with chronic pancreatitis were analyzed retrospectively to investigate the clinical aspects of chronic pancreatitis in Korea. Alcohol was the most important cause of chronic pancreatitis (51%). In 30% of the patients the causes were not evident. The most common symptoms were abdominal pain (93%) and weight loss (77%). The levels of serum amylase were elevated in only 37% of the patients even during acute exacerbation. In radiologic studies, pancreatic calcifications were found in 65% of the patients In 12 of the 53 patients, chronic pancreatitis could be dignosed only by ERCP. The most common complications were diabetes mellitus (30%), followed by pseudocyst (28%) and biliary tract obstruction (23%). The most common cause of surgical operations was the inability to differentiate chronic pancreatitis from pancreatic cancer with the conventional diagnostic tools including radiologic studies. In the patients with alcoholic chronic pancreatitis, males occupied the larger proportion, weight loss was more severe, and the degree of hyperbilirubinemia was less than in the patients with idiopathic chronic pancreatitis. Although the patients with idiopathic calcifications were older than the patients without pancreatic calcifications, there was no difference in clinical characteristics between calcific and noncalcific chronic pancreatitis exept the mean age. In conclusian, alcohol is the most important cause of chronic pancreatitis in Korea and the ERCP is very useful for diagnosis of chronic pancreatitis, but the level of serum amylase activity is not.