소아 안와질환의 전산화단층촬영 소견

김옥화 대한영상의학회 1985 대한영상의학회지 Vol.21 No.6

We analized computed tomography (CT) of 29 cases of various orbital diseases in pediatric age group. Diagnoses were confirmed by either operation or direct ophthalmoscopy. The patients were examined during the period of last 3 years. The results were as follows: 1. Of 29 cases, 21 were male and 8 were female, and the age ranged from 20 days to 15 years. 2. Intraorbital tumors were 13 cases consisting of 7 retinoblastoma, 3 pseudotumor, and 1 each of congenital teratoma, cavernous lymphangioma, and optic glioma. Of remaining 16 cases. 6 had orbital fracture. 5 persistent hyperplastic primary vitreous (PHPV), 3 vitreous opacity, and 2 primary glaucoma. 3. The CT findings of the retionblastoma were a lobulated or oval soft tissue mass density (40-60 HU) extending into the vitreous without significant enhancement on postcontrast scan. Of 7 cases, 4 had calcifications within the tumors. The extraglobal extension of the tumor was shown in 2 patinets demonstrating markedly thickened clera with enhancement and dilated optic nerve. 4. There were 5 patients with PHPV having a history of white pupil since birth, and all were affected unilateraly. Four patients had vitreous opacity and 3 of those showed either linear or branching tree-like densities within the vitreous on the postcontrast scan. Another one had a lobulated increased density protruding into the vitreous which was difficult to differenciate from the similar finding of retinoblastoma. Remaining one case demonstrated a deformed and decreased density in the lesional lens without change in the density of the vitreous. This was confirmed to be caused by persistence of the embryonic hyaloid artery attached to the posterior capsule of the lens. 5. There were 3 patients with vitreous opacity and 2 of them were dut to retinal detachment and 1 was caused by retrolental fibroplasia. The CT findings of retinal detachement were homogeneous or heterogenous opacities in the vitreous. In a case of retrolental fibroplas a, irregular, band-like density was seen along the posterior wall of the globe bilaterally. 6. Two cases of primary glaucoma showed large globe with a widened anterior chamber. 7. Among 6 cases of orbital fractures, 5 were blow-out fracture. The blow-out fractures showed fractures of the medial orbital wall or orbital floor with herniated intraorbital contents into the neighboring ethmoid or maxillary sinus.

소아의 원발성 부갑상선 기능항진증: 전신에 낭포성 섬유성 골염을 일으킨 증례보고

김옥화 대한영상의학회 1989 대한영상의학회지 Vol.25 No.4

A ll-year-old boy with 3 months history of back pain was found to have a parathyroid chief cell hyperplasis at operation. Initial roentgenograms showed dense metaphyseal lines in the knee and wrist and compression fractures involving the lumbar spine. Two months later extensive generalized osteitis fibrosa cystica developed throughout the entire skeleton inclu-ding the skull. Serum chemistry and parahyroid hormon assay were compared before and after operation. Primary hyperparathyroidism was not corrected even after the operation and the patient succu-mbed 1 year and 6 months after the initial diagnosis.

폐전이를 동반한 소아 갑상선암: -흉부 X선 검사 신티그램으로 7년간 경과를 관찰한 1례 -

김옥화 대한영상의학회 1989 대한영상의학회지 Vol.25 No.4

Miliary lung metastasis is well known in thyroid carcinoma. However thyroid carcinoma itself is very rare in children. We have seen a case of papillary adenocarcinoma of the thyroid in a 12-year old boy. He had extensive nodular lung metastases on the chest X-ray which were confirmed by 131-1 scintigraphy and biopsy of a cervical lymph node. Radioactive iodine therapy was instituted for 5 years and nodular lung metastases effectively disapperared on the follow-up chest X-ray A lung scintigraphy with 131-1 however showed residual uptake in the lung suggesting that scintigraphy is more sensitive and therfore useful for evaluating the management of the thyroid carcinoma.

종양연관성 성조숙과 과도신체발육을 동반한 소아 간암 -2예 보고-

김옥화 대한영상의학회 1990 대한영상의학회지 Vol.26 No.2

Sexual precocity in a 28-months-old boy and markedly accelerated skeletal growth with large body in a 5 years and 5 months-old-girl are reported. The former resulted from human chorionic gonadotropin-producing hapatoblastoma and the latter from cerebral gigantism associated with hepatoma, These two different disorders are discussed on the common basis of rare association of malignant hepatic tumors with precocious sexual and/or somatic growth. The clinical manifestations, chemical abnormalities, and the radiologic findings are presented with a brief review of the literature.

Lethal Neonatal Short-limbed Dwarfism

김옥화 대한영상의학회 1986 대한영상의학회지 Vol.22 No.1

We have detailed our experiences on 6 cases of neonatal lethal shore-limbed dwarfism and reviewed the articles. They include, achondrogenesis, thanatophoric dysplasia, asphysiating thoracic dysplasia, osteogenesis imperfenta confenita, and hypophospatasia lethalis. Five babies were born alive but died soon after birth and one was a stillbirth. The main cause of failure to thrive was respiratory insufficiency. Each case was having quite characteristic radiologic findings. even if the general appearances were similar to the achondroplasts clinically. Precise diagnosis is very important for genetic counselling of the parents and alarm to them the possibility of bone dysplasias to the next offsprings. For this purpose, the radiologists play major role for the correct diagnosis. We stress that when the baby is born with short-limbed dwarfism, whole body radiogram should be taken including lateral view and postmortem radiogram is also very precious.

Scrub typhus의 단순 흉부방사선학적 소견 : 경남 울산 지방의 160례에 대한 분석

김옥화 대한영상의학회 1993 대한영상의학회지 Vol.29 No.2

Scrub typhus (Tsutsugamushi disease) is an acute febrile systemic illness caused by Rickettsia tsutsugamushi that is transmitted to humans by the bite of larval-stage trombiculid mites (chiggers). The authors analyzed chest radiographic findings of scrub typhus in 160 patients in Ulsan area. One hundred and eight (67.5%) of 160 patients showed abnormal findings which included lung lesions in 108 patients (67.5%), cardiomegaly in 37 patients (23.1%), lymphadenopathy in 25 patients (15.6%) and pleural effusion in 11 patients (6.9%) among the lung lesions. interstial patterns were seen in 107 patients (66.9%), mostly fine or medium reticulonodular, and air-space patterns in 14 patients (8.8%) and combined interstitial and air-space patterns in 13 patients(8.1%). Sixty-four patients (40%) had combined chest radiographic findings. The typical chest radiographic findings of scrub typhus would be helpful in evaluation of the causes of acute fevbrile illness that occur during late fall in the endumic area.

정상 부인 및 질염환자의 질내 균종에 관한 비교 연구

김옥화 대한병리학회 1983 Journal of Pathology and Translational Medicine Vol.17 No.3

Desmoplastic Fibroma of Bone in a Toe: Radiographic and MRI Findings

김옥화,김선정,김지연,류지화,추혜정,이선주,이인숙,서경진 대한영상의학회 2013 Korean Journal of Radiology Vol.14 No.6

Desmoplastic fibroma is a rare benign primary bone tumor that is histologically similar to the soft tissue desmoid tumor. It most often involves the mandible, large long bone or iliac bone. Desmoplastic fibroma in a toe has been extremely rarely reported. Authors report a rare case of desmoplastic fibroma of bone occurring in the distal phalanx of a foot, with descriptions of the radiographic and MRI findings, correlation of the radiologic and pathologic findings, and discussion on the differential diagnosis of the tumor.

Multifocal Spinal Hemangioblastoma in von Hippel-Lindau Syndrome: A Case Report and Literature Review

김옥화 대한영상의학회 2015 대한영상의학회지 Vol.72 No.3

Hemangioblastoma is a benign vascular neoplasm of the central nervous system that occurs frequently in the cerebellum and other areas of the central nervous system including spinal cord and brainstem. Spinal hemangioblastoma can present as a sporadic isolated lesion or as a component of von Hippel-Lindau syndrome. The author presents a case of 32-year-old man with von Hippel-Lindau syndrome and spinal hemangioblastomas represented by multiple small spinal lesions, with an emphasis on the magnetic resonance imaging findings and clinical characteristics of von Hippel-Lindau syndrome-associated spinal hemangioblastomas.

Spinal Meningeal Melanocytoma with Benign Histology Showing Leptomeningeal Spread: Case Report

김옥화,김선정,추혜정,이선주,이인숙,김지연,김훈 대한영상의학회 2013 Korean Journal of Radiology Vol.14 No.3

Meningeal melanocytoma is a rare benign tumor with relatively good prognosis. However, local aggressive behavior of meningeal melanocytoma has been reported, especially in cases of incomplete surgical resection. Malignant transformation was raised as possible cause by prior reports to explain this phenomenon. We present an unusual case of meningeal melanocytoma associated with histologically benign leptomeningeal spread and its subsequent aggressive clinical course, and describe its radiological findings.