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金悅子 中央醫學社 1977 中央醫學 Vol.33 No.6
A clinical study was carried out on 314 cases under the impression of Fever of Unknown Origin from Jan. 1973 to Dec. 1976, admitted to Dept. of Internal Medicine, National Medical Center and the following results were obtained. .1) Of 87 cases with clinical impression of typhoid fever, 51 cases were confirmed by sero-bacteriologic studies as typhoid fever. Of 227 cases of febrile cases without typical clinical symptoms of typhoid fever, 54 cases were confirmed by sero-bacteriologic studies as typhoid fever. 2) The cases of previous treated with antibiotics, Sero-bacteriologically positively value was very low it is considered that the patient with FUO particul-arly who improved clinically and symptomatically on antibiotics therapy, may turn out to be the typhoid fever. 3) The patients with typical classical manifestations of typhoid fever, Serobacte riologically positively rate was very high. Bone marrow culture, typhoid cell examination in the bone marrow were very useful diagnostic methods in cases of clinically suspected typhoid fever.
腸티푸스 患者의 骨髓所見像 : 1. "Typhoid Cell"의 診斷的 價値 1. Diagnostic Value of "Typhoid Cell" in the Bone Marrow
金悅子,朴星輝 中央醫學社 1976 中央醫學 Vol.30 No.2
“Typhoid cells” were observed on the bone marrow specimens obtained from 75 cases of 114 typhoid fever patients, and the following results were obtained; 1) Typhoid cells were observed in II(50.0%) of 22 bacteriologically proved cases, in 12(48.0°%) of 25 serologically proved cases, and in 9(32.1%) of 28 clinically suspected cases which were negative bacteriologically and serologically. Total obse?rved cases of the typhoid cell were 32(42. 7%) of 75 subjects. 2) The rate of typhoid cell appearance (42. 7%) was more higher than the rate of positive culture examination (27.2%) and same result was observed even in clinically suspected cases (32. 1%). Typhoid cells were observed, at any time, during the course, even in clinically suspected cases in our series, and so it is considered that typhoid cell examination in the bone marrow is a very useful method in the diagn?osis of typhoid fever, even in clinically suspected cases.
腎症候群患者의 光學顯微鏡學的 및 電子顯微鏡學的 比較硏究
金悅子,柳秀雄,金鐘卨 최신의학사 1972 最新醫學 Vol.15 No.1
The nephrotic syndrome is a clinical term useful in describing patients with massive proteinuria, hypoalbuminemia, hyperlipidemia and edema. Other terms have been used to describe the various clinical forms of the syndrome and its relationship to a variety of pathologic lesions, namely, nephrosis, pure nephrosis, lipoid nephrosis and nephrosonephritis. The syndrome may occur in association with certain recognizing disorders. Thus it may occur: 1. In various systemic diseases which affected the kidneys, such as diabetes mellitus, systemic lupus erythematosus, amyloidosis, syphilis. 2. During the course of a chronic glomerulonephritis which was preceded months or years before by recognized attack of acute glomerulonephritis. 3. Following renal vein thrombosis or constrictive pericarditis. 4 As a result of drug toxicity (tridion, gold, bithmus etc.) or allergic manifestations (poison oak, bee stings etc. ). And it also occurs due to intrinsic renal disease, the so-called primary form of the syndrome, the glomerular changes as revealed by percutaneous renal biopsies are variable and multiple. The response to steroid therapy and clinical course are also variable. This paper represents a study of 5 adult patients, suffering from the nephrotic syndrome based on the criteria with proteinuria, hypoproteinemia, edema, hyperlipidemia, sedimenturia, normal blood pressure and usually normal conventional renal function tests, in an attempt to review the details of the clinical, laboratory and pathological findings by electron microscopic and light microscopic studies and correlated with corticosteroid therapy. The following conclusions are drawn: Histologic findings on renal biopsy specimen demonstrated that five types such as membranous type, probable proliferative type, chronic glomerulonephritis, lipoid nephrosis, and mixed type, respectedly. Complete remission was induced in no case with steroid therapy. However, purely proliferative glomerulonephritis appeared to respond better to steroid therapy with patient showing incomplete remission in both cases. Fusion of foot process was seen in 4 cases among 5 cases while the thickening of basement membranes were noted in all cases on electron microscopic study. Pathologic changes were seen in epithelial cell, such as increased number of lysosome and vaculoles, "dense body, dilatation of subbasilar spaces and proliferation of mesangial cell on electron microscopic study which were not recognized by light microscopic study.
김열자 ( Y. J. Kim ),강희태 ( H. T. Kang ),박용재 ( Y. J. Park ),이동용 ( D. Y. Lee ) 대한내과학회 1973 대한내과학회지 Vol.16 No.12
A clinical study was made on 24 cases of digitalis intoxication which were observed at the National Medical Center from 1970 to 1973 and following results were obtained. 1) Gastrointestinal symptoms were most seen in subjective symptoms of the patient and