맥주전문바 이용객의 방문빈도 결정요인 및 한계효과: 강남지역의 맥주 전문바를 중심으로

김연선,소국섭 한국외식경영학회 2008 외식경영연구 Vol.11 No.3

The focus of this study is placed on identifying determinants of visitor’s visit frequency for beer bar and respondents who were surveyed were visitors for beer bars in Gangnam Area, Seoul. For a study on demand, Poisson Model is generally applied and especially in case dependent variable appears to be non-negative integer. However, Truncated Poisson Model useful for analysing the data. collected by on-site survey was utilized. Marginal effects on independent variables which have significantly an influence on visit frequency of users for beer bar played the role of strengthening reliability for the variables. The variables are as follows: Gender, reward program, mileage card, motivation, satisfaction, selection attributes. Ultimately, the estimated result and its marginal effects would be used as basic information for beer bar’s mangers to set marketing strategy for the maximization of visitor’s demand represented by visit frequency.

Rho(D) 항원에 감작된 임산부의 산전 선택적 혈장 교환술 경험 1예

김연선,최태윤,김원배,이동화,강득용 대한임상병리학회 1995 대한임상병리학회지 Vol.15 No.4

Investigation of the Effects of Horticultural Activity Program for Mothers to Improve Relationship with Child

김연선,박신애 인간식물환경학회 2016 인간식물환경학회지 Vol.19 No.6

This study was conducted to find the effectiveness of a horticultural activity program for mothers to improve the relationship between mother and child. The target participants were comprised of 60 mothers who have a child aged between 4 to 7 years, and they were divided into the experimental group (n=30) and the control group (n=30). Those of the experimental group attended 6 sessions of the horticultural activity program in total (one session per week, 90 minutes on average), and those of the control group did not participate in the program. A survey on parenting stress, self-esteem, parenting efficacy and emotional empathy was conducted before and after the program. Its results indicated that the participants of the experimental group showed statistically significant improvements in the parenting stress level (associated with the characters of children, the relationship with them, and learning expectation). Their self-esteem also showed statistically significant improvements from perspectives of self-abasement, relationships with others, leadership and popularity, and assertiveness and anxiety. Their parenting efficacy including efficacy as a parent; anxiety and frustration as a parent; and interest and attention to parental roles showed statistically significant improvements, but there was no statistically significant difference in emotional empathy including emotional sympathy and empathic concern. In addition, the results of the satisfaction survey conducted among the mothers of the experimental group after the program indicated that their satisfaction of the overall program, the time required for a session, and the frequency of the program was high. In this study, it was found that positive changes could be realized through the horticultural activity program for the improvement of the relationship between mother and child by modifying relevant factors. It is expected that the participants of the study may experience more positive improvements if they can join horticultural activities with their child later, and it is necessary to develop programs that can engage parents in other environments based on the results of this study.

GO-30 : Clinical impact of the number of the retrieved pelvic lymph nodes in epithelial ovarian cancer

김연선,이지혜,구유진,민경진,홍진화,이재관 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

목적: To investigate the diagnostic and therapeutic effect of pelvic lymphadenectomy (PLA) according to the number of the retrieved nodes in epithelial ovarian cancer (EOC) 방법: Data were obtained from the patients who were surgically treated for newly diagnosed EOC from 2002 to 2014. According to the number of retrieved pelvic nodes, patients were divided into three groups: no-PLA, group A (1-5), and group B (>5). Survival outcomes were evaluated. 결과: Of 111 patients identified, 48 were in early stage and 63 in advanced stage. PLA was performed in 71.2%, and the mean number of retrieved pelvic nodes was 7 (1-25). Between the two groups of A (n=40) and B (n=37), there was no difference in the rate of pelvic nodes metastasis (22.5% in group A and 24.3% in group B, p=0.85). In univariate analysis, patients of no-PLA showed significantly higher rates of recurrence (OR: 2.04, 95% CI 1.02-4.09) and death (OR: 8.20, 95% CI 1.03-65.58) than those of group B, while the differences were not significant between group A and B. In multivariate analysis, nodes number was not a significant risk factor for both recurrence and death, and patient`s age and residual mass was the single most important factor associated with disease free survival and overall survival, respectively. 결론: Pelvic nodes sampling may have a similar diagnostic and therapeutic value compared to a thorough PLA in EOC. Careful targeting of node in PLA is more plausible than an attempt to remove lymph nodes as much as possible in terms of similar survival gain and low complication.

한국인의 치주염 환자로부터 분리된 Staphylococcus aureus의 다양한 항생제 감수성 양상

김연선 대한구강악안면병리학회 2012 대한구강악안면병리학회지 Vol.36 No.6

Saliva from the oral cavity was collected from 129 patients with periodontitis and 54 Staphylococcus aureus isolates were isolated from these samples. The S. aureus isolates were tested for their resistance patterns against 15 antibiotics using the disc diffusion method. The percentage of S. aureus isolates resistant to ampicillin was the highest (92.6%). In addition, the percentage of S. aureus isolates resistant to penicillin, oxacillin, cefotetan, cefepime and erythromycin was 90.7%, 11.1%, 11.1%, 9.3% and 5.6%, respectively. However, S. aureus isolates were susceptible to gentamycin, clindamycin, trimethoprim/sulfamethoxazole and vancomycin. 96.3% of S. aureus isolates were resistant to antibiotics. Among them, the percentage of two antibiotic-resistant S. aureus isolates was 74.1%, the percentage of one antibiotic-resistant S. aureus isolates was 5.6%, the percentage of three antibiotic-resistant S. aureus isolates was 3.7% and the percentage of S. aureus isolates resistant to more than 4 antibiotics was 13%. The most common multiple antimicrobial resistance pattern was AM-P. Furthermore, the percentage of methicillin-resistant S. aureus isolates was 11.1% and they were resistant to more than 3 antibiotics.

IPA기법을 활용한 한옥마을 선택속성의 중요도-만족도 연구

김연선 한국콘텐츠학회 2020 한국콘텐츠학회논문지 Vol.20 No.7

This study was conducted to research the Selection Attributes of tourists in Jeonju Hanok Village. The purpose of this study was to study the importance and satisfaction after visiting the Jeonju Hanok Village using IPA analysis, and to provide results and marketing implications. The survey was conducted from the October to the November in 2018. A total of 300 questionnaires were distributed and 258 responded questionnaires were reliable to be used as a sample. The result of the survey was analyzed by using SPSS 15.0 version for window with Paired t-test and IPA method. Frequency Analysis was also conducted for the characteristic of samples. As a result of the study, first, the cleanliness of tourist attractions was the highest among the selection attributes, and the next ranking was in the order of parking lot facilities, natural scenery, food, and weather. Second, the natural property was the most satisfactory as a selection property item that tourists visiting Hanok Village were satisfied with, followed by climate(weather), regional characteristics, historical and cultural resources, and cleanliness of tourist attractions. Third, depending on the importance-satisfaction value of the selection attribute variable perceived by tourists visiting Hanok Village, it is necessary to develop various programs in Hanok Village and prepare measures to increase tourist satisfaction. 본 연구는 전주 한옥마을 관광객들의 선택속성에 관한 연구를 수행하였다. 전주 한옥마을 방문 시에 중요하게 생각하는 중요도와 방문 후 만족도를 IPA 분석을 활용하여 연구하고, 이에 따른 결과와 마케팅적 시사점을 제공하였다. 설문 조사는 2018년 10월 초부터 11월 말까지 일대일 방식으로 진행하였고, 총 300부를 배포하였으며, 불성실하게 응답한 설문지 42부를 제외한 총 258부를 유효표본으로 활용하였다. 본 연구의 유효표본에 대한 분석은 SPSS for Window Version 15.0 프로그램을 이용하여 분석하였다. 표본의 일반적인 사항은 빈도분석(Frequency Analysis)을 실시하여 표본의 특성을 파악하였고 대응표본 T 검정(Paired Sample T-test)을 활용하여 연구하였다. 연구의 결과는 첫째, 선택속성 중에 관광지의 청결성이 가장 높았고, 그다음 순위는 주차장 시설, 자연경관, 음식·먹거리, 기후(날씨)순으로 나타났다. 둘째, 한옥마을을 방문하는 관광객들이 만족한 선택속성 항목은 자연경관이 가장 만족한 것으로 나타났고, 기후(날씨), 지역의 특색, 역사문화자원, 관광지 청결 순으로 조사되었다. 셋째, 한옥마을을 방문하는 관광객들이 지각하는 선택속성 변수의 중요도-만족도 값의 사분면 위치에 따라서 한옥마을의 다양한 프로그램 개발과 관광객의 만족도를 올리기 위한 방안 마련이 필요할 것으로 판단된다.

Rarity of TLR4 Asp299Gly and Thr399Ile Polymorphisms in the Korean Population

김연선,황유진,김성용,양선미,이기영,박이병 연세대학교의과대학 2008 Yonsei medical journal Vol.49 No.1

Purpose: Activation of the innate immune system and chronic low-grade inflammation are thought to be involved in the pathogenesis of atherosclerosis and also thought to be associated with type 2 diabetes and its complications. As a receptor for bacterial lipopolysaccharide and heat-shock proteins, Toll-like receptor 4 (TLR4) is one of the central regulators of the immune response. Recent studies have reported an association between TLR4 polymorphisms and diabetes and its complications in Caucasian populations. Materials and Methods: In this study, we analyzed the association between TLR4 gene polymorphisms in patients with features of type 2 diabetes and healthy controls in Korea. Two polymorphisms of the TLR4 gene (Asp299Gly and Thr399Ile) were examined in 225 diabetic patients and 153 healthy controls using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and single-strand conformation polymorphism (SSCP). Results: No Asp299Gly or Thr399Ile mutations were detected in any of the 378 subjects. Seven subjects from each group who had slightly different SSCP patterns were selected for sequencing, but we found no TLR4 polymorphisms on Exon3. The Asp299Gly and Thr399Ile TLR4 gene polymorphisms were absent in both groups, which was similar to the results for Japanese and Chinese Han subjects. Conclusion: Our data and other Asian data suggest that a racial difference can be found in the frequency of the TLR4 polymorphism.

국내 치과병·의원에서 분리한 S. aureus의 coagulase 및 protein A 분석에 의한 유전자 형별

김연선 대한구강악안면병리학회 2012 대한구강악안면병리학회지 Vol.36 No.5

The dental infections have been increased due to the widespread overuse and exposure to antibiotics. One of the well-known pathogens is S. aureus The pathogenic properties of S. aureus is associated with the virulence gene. The objective of this study is to investigate the distribution of virulence gene of S. aureus which may contribute to the prevention and treatment of bacterial infections. 54 strains of S. aureus were separated from saliva taken from 129 outpatients diagnosed with periodontitis from Jun. to Dec., 2010 in Seoul. 44 (46.6%) and 13 (31.7%) strains of them were obtained from 88 and 41 outpatients from the S and E dental clinics, respectively. Then, the distribution of virulence gene and genetic diversity were analyzed with the PCR technique. The result of the S. aureus isolates possessed coagulase gene and showed six polymorphism types 390~470 bp (1.8%), 550~633 bp (3.7%), 630~714 bp (9.3%), 715~795 bp (20.4%), 796~876 bp (40.7%) and 877~957 bp(22.2%) due to variable numbers of tandem repeats present within the gene. In this study it will be anticipated that this study can contribute to establish efficiently the countermeasure about the prevention and treatment of antibiotic bacterial infections.

재발 유두상 갑상선암을 수술한 경우 관해와 관련된 인자

김연선,홍석준 대한외과학회 2006 대한외과학회 학술대회 초록집 Vol.2006 No.11

GG-5 : High-risk human papillomavirus (HPV) infection in women with external genital warts

김연선,이지혜,구유진,민경진,홍진화,이재관 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

목적: Low-risk human papillomavirus is well-established cause of genital warts, but the influence of high-risk HPV (HR-HPV) remains unclear. The present study aimed to evaluate the clinical characteristics of the patients with external genital warts (EGW), and evaluate the role of high-risk HPV (HR-HPV) testing for predicting the disease progress. 방법: Data from the patients who were eligible for the clinical diagnosis of EGW between 2002 and 2014 were retrospectively reviewed. The diagnosis of EGW included condyloma acuminatum as well as all other types of symptomatic condylomatous lesion. The demographic characteristics, cytopathologic results, and clinical progress were obtained using medical records. HPV high-risk DNA testing was performed by hybrid capture II. 결과: Out of 49 patients identified, 21 (42.9%) cases had a biopsy-proven EGW. The mean age was 36.4 years (range, 21-67), and two patients were virginal women with biopsy-proven condyloma acuminatum. At diagnosis of EGW, abnormal Pap smear and positive HR-HPV were shown in half of the patients (44.7% and 50%, respectively). 48.6% of the cases were poor responders to treatment, who required repeated application of chemical agents or surgery, but the rate of poor response had no significant relation to HR-HPV positivity (p=.462). Of 21 cases followed up after resolution of the lesions, five (24%) had recurrence. Six-month recurrence-free survival was 80% in HR-HPV negative group and 70.7% in positive group (p=.426). 결론: In women with EGW, the incidence of concomitant infection with HR-HPV is fairly high, but it seems to have no effect on the progress of the lesion during treatment. Whether the HR-HPV infection is a risk factor of recurrence should be verified through multi-center large cohort studies.