눈운동장애 없이 시력 저하를 보인 해면정맥동 내경동맥류 1예

김승훈,김선웅,김범태,장지호,Seung Hoon Kim,Sun Woong Kim,Bum-Tae Kim,Jee Ho Chang 대한안과학회 2012 대한안과학회지 Vol.53 No.3

Purpose: Oculomotor disturbance is the common manifestation of intracavernous carotid aneurysm cases. Intracavernous carotid aneurysms causing compressive optic neuropathy with no oculomotor disturbance are relatively rare due to their anatomical characteristics. We experienced a case of intracavernous carotid aneurysm which resulted in a shifted supraclinoid segment of the internal carotid artery, presenting with visual loss and visual field defect with no oculomotor disturbance. Case summary: A 40-year-old woman presented with loss of vision in the right eye. A relative afferent pupillary defect was observed in this eye. Visual field test showed quadranopsia in the right eye. Magnetic resonance imaging revealed that the intracavernous carotid aneurysm had shifted the supraclinoid segment of the internal carotid artery to the superomedial position. The right optic nerve was directly molded by the shifted supraclinoid segment of the internal carotid artery at the point of the bifurcation between the anterior cerebral artery and the middle cerebral artery. A Guglielmi detachable coil (GDC) embolization was performed successfully with no operational complications. Six months after coiling, best corrected visual acuity of the right eye was 1.0, and the visual field defect had recovered in all except the superior temporal field. Conclusions: Oculomotor disturbance is frequently associated with intracavernous carotid aneurysms. Nevertheless, optic neuropathy without oculomotor disturbance may be the only sign in patients with an intracavernous carotid aneurysm that causes shifting of the supraclinoid segment of the internal carotid artery. J Korean Ophthalmol Soc 2012;53(3):486-491

류마티스 관절염 환자에서 Conserved T 세포 수용체의 CDR3 motif를 표현하는 제2형 콜라겐 특이 T세포주의 형성과 유지

김승훈,조미라,윤지희,박성환,조철수,황수연,김호연,Kim, Seung-Hoon,Cho, Mi-La,Youn, Jeehee,Park, Sung-Hwan,Hwang, Sue-Yun,Cho, Chul-Soo,Kim, Ho-Youn 대한면역학회 2001 Immune Network Vol.1 No.1

Background: To determine the molecular structure of type II collagen-specific T-cell receptors associated with rheumatoid arthritis (RA). Methods: We generated CII-specific T-cell lines of 8 RA patients by prolonged in vitro culture with bovine CII (bCII) and the immunogenic peptide (256-270) of human CII. The proliferation response towards CII stimulation was measured from the uptake of 3H-thymidine. Changes in the secretion of Th 1 and Th2 cytokines in the culture supernatent were measured by ELISA. The TCR clonotypes of these T-cells were examined by RT-PCR/SSCP analyses of all 22 $V_{\beta}$ chains. Results: T-cells from patients' tissue exhibited strong proliferation index upon CII stimulation, which was maintained up to 6 months in the culture. The secretion of INF-$\gamma$from these T-cells increased along with the duration of culture time, while the amount of IL-4 production did not show significant changes. The SSCP band patterns of patients' T-cells appear as discrete bands unlike the smeary streak produced from normal samples. Some SSCP bands, each representing selected expansion of a TCR containing certain subtype of $V_{\beta}$ peptides, appeared to be identical in more than one patients. Among these, the expansion of SSCP band representing the $V_{\beta}$ 14 CDR3 region persisted after switching the antigen to the immunogenic human peptide (256-270). Conclusion: CII-reactive T-cells expressing distinct CDR3 motifs are selectively expanded in the peripheral blood and synovial fluid of RA patients, and their persistent proliferation upon CII stimulation, as well as the production Th 1-type cytokines, may play pivotal roles in RA pathogenesis.

마이크로파를 이용한 급속 가열 연신 공정의 동역학 모델링과 정상상태 특성 해석

김승훈,백영남,허유,Kim, Seung-Hoon,Paik, Yeong-Nam,Huh, You 한국섬유공학회 2006 한국섬유공학회지 Vol.43 No.6

Fiber forming is an important technology for producing multi-functional goods that have a flexible and structured plane form by using raw material with special properties. This research reports on the metal fiber manufacturing technology that adopted induction heating and drawing, but without use of dies that are now installed in the conventional wire drawing processes. Heating wires allows the drawing process to build up necking and to shorten the process by reducing the process steps so that a new and efficient production method of metal fibers is to be conceived and developed. A new device that can process a single wire consists of three major parts: the drawing part comprised of capstans, that is, feeding roll and take-up roll with specially hardened circumferential surface, the change gear part with continuously controllable draw ratio, and the heating part that includes a heating source and an energy propagation channel and an electromagnetic wave absorber With this device feasibility of the induction heating method is tested and the characteristics of the metal wire drawing process is analyzed. Results show that the microwave can be applied to attenuate the metal wire as a heating source and the experimental profiles of the cross-sectional area in the heated drawing zone under a steady state condition coincide well with those from theoretical model. The diametric variation of the drawn wires increased, however, as the drawing ratio increased.

$(HF)_2(CO)$ 분자착물에 관한 Ab Initio 연구

김승훈,Kim, Seung Hoon 대한화학회 1998 대한화학회지 Vol.42 No.6

$6-31+G^{\ast}^{\ast}와\;6-311+G^{\ast}^{\ast}$의 기본조를 사용해서 이합체 분자착물 FH…FH, FH…CO, FH…OC 뿐만 아니라 $(HF)_2(CO)$의 형성가능한 두가지 삼합체 분자착물들에 대해서 HF-SCF, MP2 그리고 B3LYP 계산을 수행했다. 이 삼합체 분자착물들에 대한 여러 가지 바닥상태 성질들을 구하였으며, 대응하는 단위체들과 이합체들의 성질들과 비교하였다. FH…CO가 FH…OC에 비해 평균 0.85 kcal/mol 만큼 안정했고, F-H…F-H…C≡O가 F-H…F-H…O≡C 보다 1∼2 kcal/mol 만큼 안정한 것으로 계산되었다. 삼합체 분자착물 형성에 따른 C≡O stretching band 는 그들의 이합체들(FH…CO, FH…OC)에 비해 각각 24, $37\;cm^{-1}$만큼, H-F stretching band는 각각 $54, 353\; cm^{-1}$만큼 red shift 되는 것으로 평가되었다. The HF-SCF, MP2 and B3LYP calculations have been performed on the two conceivable clusters $(HF)_2(CO)$ trimers as well as their dimer complexes FH…FH, FH…CO and FH…OC applying $6-31+G^{\ast}^{\ast}$, and $6-311+G^{\ast}^{\ast}$ basis sets. A variety of ground state properties of these trimer complexes have been listed, and compared with corresponding properties of isolated monomers and combined dimers. It was calculated that FH…CO is more stable than FH…OC by average 0.85 kcal/mol and F-H…F-H…C≡O is more stable than F-H…F-H…O≡C by 1-2 kcal/mol. The C≡O stretching bands of the F-H…F-H…C≡O and F-H…F-H…O≡C were red shifted by 24, $37\;cm^{-1}$ compared with the FH…CO and FH…OC respectively. Also, H-F stretching bands were red shifted by 54 and $353\;cm^{-1}$.

스펙트럼 영역 빛간섭단층촬영기를 이용한 근시 정도에 따른 황반 구조의 정량적 분석

김승훈,박주연,박태관,온영훈,Seung Hoon Kim,Joo Youn Park,Tae Kwann Park,Young-Hoon Ohn 대한안과학회 2011 대한안과학회지 Vol.52 No.11

Purpose: To investigate the correlation of macular retinal thickness and refractive error using spectral-domain optical coherence tomography (SD-OCT). Methods: A total of 120 eyes with no posterior abnormalities were enrolled in the present study. Subjects were divided into 3 groups based on their spherical equivalent. Visual acuity, refraction, slit lamp examination, tonometry and fundus examination were performed. Retinal thickness between the RPE and IS/OS junction was measured at the fovea, 1 mm (inner ring) and 2 mm (outer ring) superiorly, inferiorly, nasally and temporally using SD-OCT. Overall average thickness, average foveal thickness, and the inner and outer ring macular thickness were measured. Results: The average foveal thickness was significantly greater in the high myopic eyes than in the low to moderate myopic and emmetropic eyes (p = 0.001). However, the RPE-IS/OS junction thickness of the foveola and the outer macular thickness were significantly lower (p = 0.001, p = 0.002) in the high myopic eyes. There was a weak, but significant negative correlation between refractive error and average foveal thickness (r = -0.38, p = 0.001). A positive correlation was found between refractive error and the RPE-IS/OS junction thickness (r = 0.40, p = 0.001). Conclusions: Macular retinal thickness is related to refractive error in normal subjects. Effects of eyeball elongation are more apparent in high myopic eyes than in low to moderate myopic eyes. A significant decline in the RPE-IS/OS junction thickness suggests the photoreceptor outer segments in the foveola are damaged in high myopic eyes. J Korean Ophthalmol Soc 2011;52(11):1286-1295

정시안에서 스펙트럼영역 빛간섭단층촬영기를 이용한 연령과 성별에 따른 황반 두께의 변화

김승훈,최경식,이성진,Seung Hoon Kim,Kyung Seek Choi,Sung Jin Lee 대한안과학회 2011 대한안과학회지 Vol.52 No.3

Purpose: To evaluate the changes in macular thickness with regard to age and gender in normal subjects with emmetropia using spectral domain optical coherence tomography. Methods: The present study consisted of 90 healthy subjects (162 eyes) with no ophthalmic evidence of retinopathy and who had emmetropic eyes. The data from macular measurements using spectral domain optical coherence tomography was analyzed according to the groups divided by age (Group 1: 0 to 19 years of age, Group 2: 20 to 39 years of age, Group 3: 40 to 59 years of age, Group 4: 60 to 80 years of age) and gender. Results: Macular thickness of the central circle was 253.40 ± 23.03 μm in all subjects. There was no significant change with age (p > 0.05). However, the measurements at the inner (3 mm) and outer circle (6 mm) showed a reduction of macular thickness with age (p < 0.05). The macular thickness at the central and inner circle was significantly lower in the female subjects (p < 0.05). In group 3 and 4, macular thickness at the central circle in males was greater than in females. In group 3, the average inner macular thickness in males was significantly greater than in females (p < 0.05). Conclusions: In normal subjects with emmetropia, there are statistically significant differences in macular thickness between subjects of different age and gender. The results from the present study can be expected to provide a reference value for evaluating macular disease. J Korean Ophthalmol Soc 2011;52(3):299-307

PerFix<SUP>Ⓡ</SUP> Plug을 이용한 무긴장 탈장 교정술의 단기 성적 보고

김승훈(Seung Hoon Kim),정재희(Jae Hee Chung),송영택(Young Tack Song) 대한외과학회 2003 Annals of Surgical Treatment and Research Vol.64 No.5

큐브 위성 INHASAT의 전력계 분석

김승훈(Seung-Hoon Kim),김세준(Se-Jun Kim),김정훈(Jeong-Hun Kim),박경인(Kyung-In Park),유창경(Chang-Kyung Ryoo),최기영(Kee-Young Choi) 한국항공우주학회 2020 한국항공우주학회 학술발표회 논문집 Vol.2020 No.7

2019년 자살 관련 지표들과 추이

김승훈 ( Seung Hoon Kim ),이두웅 ( Doo Woong Lee ),권준현 ( Junhyun Kwon ),양지은 ( Jieun Yang ),박은철 ( Eun-cheol Park ),장성인 ( Sung-in Jang ) 한국보건행정학회 2021 보건행정학회지 Vol.31 No.2

This study aimed to update suicide-related indicators including suicidal ideation, suicide attempts, and the number of suicidal deaths. Based on up-to-date information, we observed the trends of suicide-related indicators. In this study, five data sources were used to observe the trends of suicide-related indicators: Statistics Korea (1983-2019), Korean National Health and Nutrition Examination (KNHANES, ‘07-13, ‘15-19), Korean Community Health Survey (KCHS, ‘08-09, ‘13, ‘17), Korean Wealth Panel Study (KOWEPS, ‘12-19), and Korea Health Panel Survey (KHP, ‘10-13, ‘16-17). The suicide rate, which peaked in 2011, declined until 2017 and then started to rise again from 2018, recording a suicide rate of 26.9 per 100,000 people in 2019. The rate of suicidal ideation estimated based on the recently available data was 4.62% (KNHANES, ‘19), 3.51% (KHP, ‘16), 2.87% (KHP, ‘17), and 1.70% (KOWEPS, ‘19). That of suicide attempt as recent year was 0.43% (KNHANES, ‘19), 0.07% (KOWEPS, ‘19). Annual percentage change of death by intentional self-harm was -2.11% (Statistics Korea), and that of suicidal ideation was -14.7% (KNHANES), -2.5% (KCHS), -10.6% (KOWEPS), and -11.3% (KHP). Annual percentage change of suicide attempt was -5.0% (KNHANES), -4.4% (KCHS), and -11.3% (KOWEPS). The lower the income level, the higher the probability of experiencing suicide ideation and suicide attempts. Considering the recent increase in suicide rate in contrast to the continuing decline in suicidal ideation and suicide attempts, continuous data observation and appropriate policies regarding suicide prevention are needed.

아동권리협약 채택 20주년의 의미와 과제

김승훈(Seung-Hoon Kim) 大韓赤十字社 人道法硏究所 2009 人道法論叢 Vol.- No.29

아동은 앞으로 미래를 이끌어갈 중요한 자원이며 자산이다. 아동은 잘 성장하고 자신의 잠재력을 최대한 발달시키면서 성장할 권리를 가지며, 사회나 성인들은 이를 지원할 의무를 가지는 것이다. 따라서 이들에게도 독립적인 인간으로서 성인과 동등한 권리가 있다는 것이 유엔 아동권리협약의 지향점이다. 아동의 권리보장 문제는 아직 우리 사회에서 그리 익숙한 개념은 아니지만 국제적으로는 아동권리에 대한 관심이 매우 높은 것이 현실이다. 특히 아프리카 일부 국가에서의 아동이 처한 모습을 보면, 그 나라의 사회문화적인 수준을 알 수 있을 정도이다. 현대사회에서는 수동적인 아동보호에서 능동적인 아동권리 보장이라는 적극적인 아동권리사상이 발달하였지만 아동이 보호의 대상에서 권리의 주체로 인식되기까지 높은 벽을 지나야 했으며 앞으로도 무한한 인내가 필요할 것이다. 아동의 인권을 침해하는 것은 헌법에서 보장하는 국민의 기본권을 위반하는 것이다. 동시에 정부가 아동의 인권 보호를 소홀히 하는 것은 명백히 국제법의 위반이기도 하다. 아동권리협약’ 제19조 제1항은 “당사국은 아동이 부모, 후견인, 기타 아동 양육자의 양육을 받고 있는 동안 모든 형태의 신체적 · 정신적 폭력, 상해나 학대, 방임 또는 유기, 성적 학대를 포함한 혹사나 착취로부터 아동을 보호하기 위하여 모든 적절한 입법적 · 행정적 · 사회적 및 교육적 조치를 취하여야 한다”라고 규정하였다. 따라서 정부는 아동권리협약이 채택된 20주년을 기념하고 그 숭고한 이념을 보급하기 위하여 협약에서 규정한 권리 내용을 전 국민들에게 보급할 수 있는 방안의 마련과, 기존 국내법이 아동권리협약의 내용과 배치될 경우에는 개정을 위하여 노력하여야 할 것이다. 아동의 권리를 지키고 실현시키는 일은 정부, 비정부, 국제기구, 가정, 학교를 망라한 우리 모두의 책임이기 때문이다. Children are important resources and assets to lead the future. Responsibility for the rights of children will ultimately hinge on the translation of agreed principles into national laws, plans of action, and allocation of resources. Children have a privilege to develop their potential capacities while growing up, so that the society or adults will have the obligation to support them. Therefore they are also independent humans what shall enjoy same privileges as adults. This is the convention on the Rights of the Child. The problem with the rights of the child is the society not being familiar with the concept in which it only draw interests in the international scene. In particular, if you see a child in a critical condition in any country in Africa, it could be associated with culture. In modem society, protecting children from passive to active rights of children that rights of child idea is developed positively. However, it must pass through high walls and it will need infinite perseverance before the target of protection of child recognizes to the subject of rights. Infringing the constitutional rights of child is to guarantee people's basic rights are violated. At the same time, the governments neglect of the child's human rights protection is clearly a violation of international law. The Convention on the Rights of the Child, article 19 para. 1, clearly states that, "States Parties shall take all appropriate legislative, administrative, social and educational measures to protect the child from all forms of physical or mental violence, injury or abuse, neglect or negligent treatment, maltreatment or exploitation, including sexual abuse, while in the care of parents, legal guardians or any other person who has the care of the child." Therefore, the government should stipulate right information and action plan to all people, and exert more efforts if the existing laws placed with contents of convention on the rights of child for revision, as well as celebrating 20th anniversary the convention on the rights of child for which was adopted by governments to bring about noble ideas. To protect and work to realize the rights of a child is not only our responsibilitybutalsothegovemments, non-government and international organizations, home and school.