http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
김승협 ( Seung Hyup Kim ),김유선 ( You Sun Kim ),김서현 ( Seo Hyun Kim ),이동훈 ( Dong Hoon Lee ),박세준 ( Se Jun Park ),윤서영 ( Seo Young Yun ),김대영 ( Dae Young Kim ),이정훈 ( Jeong Hun Lee ),문정섭 ( Jeong Seop Moon ) 대한소화기학회 2016 대한소화기학회지 Vol.67 No.4
Proctitis is an inflammatory change of rectal mucosa induced by various agents or stimulus. Among many etiologies, it may be caused by medical treatments such as radiation or antibiotics. Proctitis usually presents with rectal ulcer but abscess formation is uncommon. Therapy using Ssukjwahun exerts its effect by directly applying the smoke around genital area and anus with various medicinal brewed herbs, especially worm-wood. Secondary metabolite of this plant, monoterpene, is known to facilitate circulation, exert anti-inflammatory effect, and help control pain. Herein, we report an unusual case of infectious proctitis presenting with rectal ulcer and abscess formation after perianal application of warm steam made by Artemisia asiatica smoke for treatment of dysmenorrhea. (Korean J Gastroenterol 2016;67:212-215)
간내 담관암의 전산화단층촬영소견의 특징 - 간 흡충중과의 연관성을 중심으로 -
최병인(Byung Ihn Choi),박재형(Jae Hyung Park),김주완(Chu Wan Kim),김승협(Seung Hyup Kim),김원홍(won Hong Kim),한만청(Chung Yong Kim),김정룡(Eun Sil Yu),김용일(Man Chung Han),유은실(Chu Wan Kim) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.1
N/A 22 patients with intrahepatic cholangiocarcinomas of the liver were examined with computed tomography (CT). Initial symptom was nonspecific such as upper abdominal discomfort or pain in majority. There was no patient with jaundice or liver cirrhosis. 13 patients (59%) showed positive skin or stool test for clonorchis sinensis. 17 patients had the peripheral type of cholangiocarcinoma and five patients had the main duct type. The tumors showed low-density rnasses in pre and postcontrast CT scan in all cases vith wide variation of homogeneity. The tumor margins were irregular in 18 patients (82%) and the degree of contrast enhancement of the tumor was minimal in 19 patients (86%). 13 patients, who had the clonorchiasis, showed mild, and diffuse dilatation r>f the intrahepatic bile duct in addition to the low-density mass. 12 patients (55%) showed extrahepatic metastasis. In peripheral type of the tumor, five patients showed fine, stippled or aggregated powderlike high-density areas in precontrast Cl scan that vere mucinous substances within the mass on pathologic section. Eleven patients showed markedly low-density masses even in postcontrast CT which corresponded to diffuse, microcystic change of the tumor on resected specimen. In main duct type, all patients showed focal ductal dilataion around the low-density mass. Intrahepatic cholangiocarcinoma should be the primary diagnostic consideration when characteristic CT findings are detected in noncirrhotic patient with clonorchiasis.
이세한(Se Han Lee),이정표(Jung Pyo Lee),김세중(Se Joong Kim),김성균(Seong Gyun Kim),김연수(Yon Su Kim),하종원(Jong Won Ha),안규리(Curie Ahn),김승협(Seung Hyup Kim),한진석(Jin Suk Han),김성권(Suhng Gwon Kim),이현순(Hyun Soon Lee),이정상( 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.5
Renal lymphangiectasia is a rare cystic kidney disorder. This disorder has been termed renal lymphangioma, renal lymphangiomatosis, pararenal lymphatic cyst. We report on a 32-year-old man admitted with complaints of abdominal discomfort, in whom unilateral renal lymphangiectasia with renal vein thrombosis was diagnosed. Abdominal computed tomography revealed left perirenal fluid collection with multiloculation. Left renal vein was completely obliterated due to thrombosis and inferior vena cava (IVC) was partially obliterated. Perirenal fluid collection and renal vein thrombosis were treated initially with percutaneous drainage and anticoagulation therapy. The biochemical features of the drained fluid were compatible with lymphatic fluid. Since there was no decrease in the amount of daily drainage, left nephrectomy and IVC thrombectomy was performed on the 34th day of hospitalization. Left kidney was enlarged (15×10×18 ㎝, 750 g) and composed of numerous smooth, thin-walled cysts. Pathologic diagnosis was renal lymphangiectasia.
김상준(Sang Joon Kim),박재형(Jae Hyung Park),김승협(Seung Hyup Kim),노동영(Dong Young Noh),정인목(In Mork Jung) 대한소화기학회 1991 대한소화기학회지 Vol.23 No.3
Hepatic artery aneurysms are rare lesions and have ifficulty in diagnosis and treatment. Upper abdominal pain accompanied by recurrent gastrointestinal bleeding can be a suspicious sign of the hepatic artery aneurysm. Ultrasonography is the screening diagnostic tool, but preoperative evaluation of the aneurysm and collaterals to the liver is well accomplished by the angiography. Surgical therapy is needed because the aneurysms have a significant propensity toward rupture and its high mortality. Maintanence of the hepatic blood flow after artery ligation should be considerd, but hepatocellular survival is possible due to collaterals, increased oxygen uptake from portal vein. Percutaneous transcatheter embolization is alternative to surgery and has gained clinical application in recent years, especially intrahepatic aneurysm and active bleeding. We experienced a 53-year old woman who underwent recurrent upper gastrointerstinal bleeding and duodenal ulcer was suspected by endoscopy. She was intractabel to the surgery to ulcer bleeding and suspicious mass was paepated on the and portion of the duodenum, so, angiography was done and revealed that the thumb tip sized proper hepatic artery aneurysm was presnet. We treated it successfully with transcatheter coil embolization & report it now.
한준구,박재형,김형석,박길선,이구,김승협,최병인,한만청,이효석,김정룡,Han, Joon-Koo,Park, Jae-Hyung,Kim, Hyung-Suk,Park, Kil-Sun,Lee, Goo,Kim, Seung-Hyup,Choi, Byung-Ihn,Han, Man-Chung,Lee, Hyo-Suk,Kim, Chung-Yong 대한영상의학회 1990 대한영상의학회지 Vol.26 No.4
Hepatocellular carcinoma(HCC) is one of the most common malignancies in Korea. Despite of recent advances in diagnostic and surgical technics, early diagnosis of HCC is difficult and chance of surgical resection is still very low because of the multiplicity of tumors and associated liver cirrhosis. Transarterial chemoembolization(TAE) is a proven effective mean of treating HCC whether it is operable or not. The authors analyzed the survival data from 193 patients of HCC who were diagnosed and had undergone TAE in Seoul national University Hospital from February 1987 to January 1988. Methods of TAE were the infusion of mixture of Lipiodol and Adriamycin with or without following administration of Gelfoam soaked in Mitomycin C. One year survival rate of all 193 cases was 53%. One year survival rate was affected by the presence and the degree of arteriovenous(AV) fistula as well as Child class, stage of the disease and degree of arteriovenous(AV) fistula as well as Child class, s age of the disease and degree of portal vein involvement. One year survival rte was 55.9% for Child class A, 46.9% for class B, 35% for class C, and 58.4% for stage I, 46.9% for stage II, and 38.9% for stage III. Patients who had the involvement of main portal vein revealed one year survival rate of 30.6%, whereas 44.1% for the patients who had the involvement of first order branch and 60.5% for the patients who had no involvement of portal vein or involvement was noted in smaller branches. Patients who had AV fistula of grade(┼┼) ahd one year survival rate of 18.5%, 27.6% for (┼) group, and 60.1% for(-)group. Patients who had undergone Gelfoam embolization after the infusion of Lipiodol-Adriamycin mixture had one year survival rate of 57.3% whereas who had not undergone gelfoam embolization revealed one year survival rate of 47 %. These results suggest that TAE is a very effective mean of treating HCC and the presence of AV firstula is one on the poor prognostic factors of HCC. A though this study lacks comparison between the same clinical groups, it is suggested that Gelfoam embolization after the infusion of Lipiodol-Adriamycin mixture may improve the prognosis of the patients.
수술로 절제한 위장관기질종양에서 Ki-67 발현의 예후적 중요성
정성연 ( Seong Yeon Jeong ),박원우 ( Won Wo Park ),김유선 ( You Sun Kim ),박영일 ( Young Il Park ),김승협 ( Seung Hyup Kim ),윤원재 ( Won Jae Yoon ),문정섭 ( Jeong Seop Moon ),이병모 ( Byung Mo Lee ),홍성우 ( Seong Woo Hong ),강 대한소화기학회 2014 대한소화기학회지 Vol.64 No.2
목적: 현재까지 위장관기질종양(GIST)을 양성과 악성으로 분류할 수 있는 명확한 조직학적 기준은 없지만, 전이나 재발을 일으킬 수 있는 위험도를 종양세포의 유사분열 수와 종양의 크기를 기준으로 나누고 있다. Ki-67은 세포 증식의 표지자로 사용되는 단백질로, GIST의 예후 인자로의 가능성이 주목되고 있다. 이에 저자들은 수술 치료를 시행한 GIST 환자 중 Ki-67 면역조직화학염색을 시행한 32예의 Ki-67 지수와 유사 분열 지수와의 관련성, GIST의 재발률 및 무병 생존율에 대하여 분석 검토하여 보았다. 대상 및 방법: 인제대학교 서울백병원에서 수술 치료를 통하여 GIST를 제거한 32명의 환자를 대상으로 연구를 시행하였고 환자들의 의무기록을 통하여 성별, 연령, 증상 등의 임상적 특징과, 종양의 크기, 위치 등의 조직학적 특징 및 재발률에 대하여 조사하였다. 결과: NIH 진단기준으로 very low risk는 4예, low risk는 9예, intermediate risk는 14예, high risk는 5예였다. Ki-67 지수는 1-18%의 범위 내에 있었고, 평균은 5.56±4.48%였다. 평균 추적관찰 기간은 35.72±29.04개월이었고 관찰 도중 6 예(18.7%)에서 재발 혹은 전이가 발견되었다. Ki-67 지수가 5% 이하인 군의 누적 무병 생존율은 12개월, 24개월, 60개월에 각각 100%, 100%, 86%였다. 반면 Ki-67 지수가 5% 초과인 군의 누적 무병 생존율은 12개월, 24개월, 60개월에 각각 82.1%, 70.3%, 46.9%로 Ki-67 지수가 5% 이하인 환자에 비하여 무병 생존율에 유의한 차이를 보였다(p=0.007) 결론: Ki-67 지수가 5% 초과할 경우 GIST 재발의 고위험성을 시사한다. 향후 Ki-67 지수의 표준화와 치료 방향의 결정에 미치는 Ki-67 지수의 역할에 대한 연구가 필요하다. Background/Aims: Assessment of malignant potential in gastrointestinal stromal tumor (GIST) is still problematic. The maximum tumor diameter and the mitotic index are generally used as an index of malignancy of GISTs. The Ki-67 labeling index has recently been used as an index of cell growth. The aim of this study was to investigate the prognostic value of K -67 in GIST. Methods: We retrospectively reviewed the medical records of 32 patients with GIST who underwent surgical resection at Inje University Seoul Paik Hospital. We analyzed their Ki-67 expression, histologic finding, and prognosis. Results: According to the tumor size and mitotic count, 4 patients were classified as very low risk, 9 patients as low risk, 14 patients as intermediate risk and 5 patients as high risk. The average Ki-67 index was 5.56±4.48%. The median follow-up duration was 35.72±29.04 months, and local/distant recurrences were observed in 6 (18.7%) patients. The overall cumulative disease free survival rates in patients with Ki-67 index ≤5% at 1 year, 2 years, and 5 years were 100%, 100%, and 86%, respectively. The overall cumulative disease free survival rates in patients with Ki-67 index >5% were at 1 year, 2 years, and 5 years were 82.1%, 70.3%, and 46.9%, respectively. There was significant relationship between elevated Ki-67 and disease free survival rate (p=0.007). Conclusions: Our study suggests that Ki-67 index >5% confers a higher risk of relapse in patients with GIST. Future work should focus on standardization of Ki-67 assessment and specification of its role in making treatment decisions.(Korean J Gastroenterol 2014,64:87-92)
Doppler초음파를 이용한 발육지연태아의 흉부하강대동맥 혈류속도파형의 양상
윤보현 ( Bo Hyun Yoon ),이필량 ( Pyl Ryang Lee ),김승협 ( Seung Hyup Kim ),신희철 ( Hee Chul Shin ),김승욱 ( Syng Wook Kim ) 대한주산의학회 1990 大韓周産醫學會雜誌 Vol.1 No.1
A real time sector scanner with a pulsed Doppler transducer was used to study and compare the blood flow velocity wavefroms of fetal descending thoracic aorta in 97 normal pregnancies and 50 cases of fetal growth retardation with 170 and 67 examinations, respectively. All pregnancies were in the third trimester. In both groups, A / B ratio, resistance index, and pulsatility index remained unchanged with increasing gestational age. In growth reatarded pregnancies, there were singnificant increases in A / B ratio, pulsatility index, and resistance index, and significant decrease in end diastolic velocity compared to those in normal pregnancies(p<0.05), reflecting increased peripheral vascular resistance. In the 8 distressed fetuses, Doppler findings were more pathological than those in the fetuses without distress. This method may be of value in the evaluation of fetal well-being in risk pregnancies by giving an early sign of hemodynamic changes in developing hypoxia.