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      • KCI등재

        Pilot Study: Effects of Acupuncture on the Muscle Cramps of Liver Cirrhosis Patients

        김승모,곽민아,주정현,신임희,김경순,이창형 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.3

        Objective: The purpose of this clinical trial is to examine the efficacy and safety of electroacupuncture on liver cirrhosis patients suffering from muscle cramps. Methods: A total of 14 liver cirrhosis patients with muscle cramps were treated by electroacupuncture three times a week for four weeks (12 times total). The electrical stimulation was a frequency of 100 Hz. Evaluation of the muscle cramps was measured by a questionnaire of subjective symptoms. The patients’ condition was evaluated four times over a period of eight weeks. We also assessed the deterioration of liver disease using the Child-Pugh score and blood tests. Results: This study proves that four weeks of electroacupuncture treatment is effective in reducing the frequency of muscle cramps and that the effects of electroacupuncture treatment lasted during another four-week follow-up period after treatment. Conclusions: This study suggests that electroacupuncture treatment is beneficial for improving muscle cramps in liver cirrhosis patients (p=0.000). Electroacupuncture is thought to be a safe treatment for liver cirrhosis patients with muscle cramps without contributing to the worsening of liver function. Further study with a larger sample size is needed to confirm our findings.

      • KCI등재

        시호(柴胡)가 총담관결찰 및 taurocholate 부하(負荷) 흰쥐 간의 MAO 활성에 미치는 영향

        김승모,왕오호,박재현,Kim, Seong-Mo,Wang, Wu-Hao,Park, Jae-Hyun 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.2

        Object : This study was carried out to examine the effect of Bupleuri Radix on experimental cholestasis, and make clear apart of this mechanism. Methods : Two models of common bile duct ligation group and taurocholate load group after common bile duct ligation were induced, and Bupleuri Radix extract was taken orally for 14 days. In the 1, 2, 4, 7 and 14 days after treatment, the mitochondrial and microsomal monoamine oxidase(MAO) A and B activities in liver were measured. Results : The mitochondrial MAO A and B activities increased in both Blupleuri Radix treated group after common bile duct ligation and Blupleuri Radix treated group after taurocholate load and common bile duct ligation. MAO A increased in Blupleuri Radix treated group after taurocholate load and common bile duct ligation, and MAO B increased in Blupleuri Radix treated group after common bile duct ligation. The microsomal MAO A activities increased in both Blupleuri Radix treated group after common bile duct ligation and Blupleuri Radix treated group after taurocholate load and common bile duct ligation. Conclusion : According to the result, it is consider that Blupleuri Radix not only improves cholestatis in liver, but also decreases a genetic synthesis of taurocholic acid.

      • KCI등재

        전체층황반원공을 동반한 망막색소변성환자의 수술적 치료: 증례보고

        김승모,여준형,김중곤 대한안과학회 2019 대한안과학회지 Vol.60 No.3

        Purpose: To report the long-term outcome after surgical repair of a full-thickness macular hole (FTMH) in a patient with retinitis pigmentosa (RP). Case summary: A 55-year-old male who had been diagnosed with retinitis pigmentosa in both eyes 5 years earlier presented with decreased visual acuity in his left eye over the last 6 months. On examination, his Snellen best-corrected visual acuity (BCVA) was 1.0 in the right eye and 0.3 in the left eye. Slit-lamp examination of the anterior segment was remarkable only for posterior chamber intraocular lenses in each eye. Fundus examination demonstrated extensive bony spicule-like pigmentation in the mid-peripheral region in both eyes and a FTMH with approximately one-third disc diameter in the left eye. The optical coherence tomography (OCT) findings confirmed a FTMH with a surrounding cuff of intraretinal fluid and vitreomacular traction in the left eye. The patient underwent 23-gauge pars plana vitrectomy (PPV) with indocyanine green-assisted internal limiting membrane peeling and gas tamponade. One week postoperatively, an anatomically well-sealed macular hole was confirmed by OCT. At the 3-month postoperative follow-up, the BCVA improved to 0.63 and the hole remained closed until his last follow-up (postoperative 6 years). Conclusions: Although macular hole is a rare occurrence in RP patients, it should be considered as a cause of significant visual loss in patients with this disorder. Our case suggested that over the long-term, PPV may be tolerable in the management for FTMH in RP. 목적: 망막색소변성환자에서 발생한 전체층황반원공에 대해 수술적 치료 후 장기 결과를 보고하고자 한다. 증례요약: 5년 전 망막색소변성을 진단받은 55세 남자가 6개월 전 시작한 좌안의 시력저하를 주소로 내원하였다. 내원 시 최대교정시력은 우안 1.0, 좌안 0.3이었고, 세극등검사상 양안 후방의 인공수정체 이외의 특이 소견은 없었다. 안저검사상 양안 망막 중간주변부에 광범위한 골소체 모양의 색소침착 및 좌안 황반부에 시신경 크기 1/3 정도의 황반원공이 확인되었고, 빛간섭단층촬영검사상 유리체황반견인을 동반한 전체층황반원공과 원공둘레의 망막내액이 관찰되었다. 이에 수술적 치료를 계획하였으며, 유리체절제술 및 인도시아닌그린을 이용한 내경계막벗김술, 과불화프로판을 이용한 안내가스충전술을 시행하였다. 술 후 1주일에 시행한 빛간섭단층촬영검사상 황반원공은 해부학적으로 폐쇄된 것이 확인되었으며, 술 후 3개월째 좌안 최대교정시력은 0.63까지 호전되었다. 마지막 방문(술 후 6년)까지 시력과 황반원공의 폐쇄는 안정적으로 유지 중이다. 결론: 망막색소변성환자에서 전체층황반원공이 합병된 경우 내경계막벗김술을 동반한 유리체절제술이 치료 방법으로 고려될 수 있다.

      • KCI등재

        Herbal Medicine for the Treatment of Viral Hepatitis B and C: A Systematic Review of Randomized Controlled Trials

        김승모,이유리,조나경,최홍식,김경순,Kim, Seung-mo,Lee, Yu-ri,Cho, Na-kyung,Choi, Hong-sik,Kim, Kyung-soon The Society of Internal Korean Medicine 2021 大韓韓方內科學會誌 Vol.42 No.4

        본 연구는 B형 및 C형 간염에 대한 한약 치료의 효과를 평가하기 위해 무작위 임상연구를 대상으로 체계적 문헌고찰 및 메타분석을 시행하였다. 검색엔진은 EMBASE, Pubmed, NDSL, KMBASE, KISS, KISTI, Koreamed, Koreantk, Oasis database를 이용하였으며 국내의 검색 엔진 키워드는 '간염' 또는 '바이러스성간염', '한약', '무작위 배정 임상시험'을, 국외 검색 엔진 키워드는 'hepatitis' or 'viral hepatitis' and 'herbal medicine' or 'traditional chinese medicine' and 'randomized controlled trial'을 이용하였다. 연구 결과 15개의 무작위배정 임상시험을 선택되었으며, 그 중 통계적으로 유의미한 결과를 나타낸 연구는 한약과 양약 복합치료군이 양약을 투여한 대조군에 비해 HBV DNA loss에서 높은 효과를 보였다. 한약과 양약 복합치료군이 양약을 투여한 대조군에 비해 HBeAg loss에서 통계적으로 유의한 효과를 보였으며, 한약과 양약 복합치료군이 양약을 투여한 대조군에 비해 ALT가 감소하였다. 본 연구는 B형 및 C형 간염환자를 대상으로 한약의 효과를 확인하기 위해 기존에 시행된 RCT 연구를 대상으로 체계적 문헌고찰을 시행하였으며, 한약과 양약의 복합치료가 양약 단독치료에 비해 치료효과가 더 높은 것으로 나타났다. The aim of this study was to perform a systematic review and meta-analysis of randomized controlled trials (RCTs) that applied herbal medicine to treat viral hepatitis B and C in order to determine the therapeutic efficacy of herbal medicine. EMBASE, Pubmed, NDSL, KMBASE, KISS, KISTI, Koreamed, Koreantk, and Oasis databases were searched to identify RCTs. The selected studies were assessed by the Cochrane group's risk of bias tool. A total of 15 RCTs were selected, and the hepatitis B virus (HBV) DNA reduction was significantly higher in patients treated with herbal medicine combined with Western medicine than in patients treated with herbal medicine. Herbal medicine combined with Western medicine was also superior to Western medicine alone in achieving hepatitis B e-antigen (HBeAg) and alanine aminotransferase [ALT] reduction. Only herbal medicine alone was not superior to Western medicine treatments in achieving HBV DNA, HBeAg, and ALT reduction.

      • KCI등재후보

        민영의료보험이 의료이용에 미치는 영향 : 국내 실증적 연구의 고찰

        김승모,권영대 보건의료산업학회 2011 보건의료산업학회지 Vol.5 No.4

        The arguments exist that private health insurance(PHI) policy holders tend to use the health care services more than non-policy holders due to their little out-of-pocket spending, resulting in the adverse effects on the finances of National Health Insurance. This study aims to increase the objective understanding of the issue and to draw a direction of further research, by reviewing the articles, reports and statistics which examined the effects of purchasing PHI policies on health care utilization. Significant differences in healthcare utilization, except for the very partial increase of utilization in outpatient settings, have been not found. The similar trends of the results have existed in a few previous studies which tried to control the endogeneity of medical use and health insurance with latent variables which affect the decision on medical use and health insurance. However, we can not exclude the potential change of healthcare utilization patterns because the portion of the insured of indemnity PHI is becoming rapidly larger in the market. For further research, we should try to obtain the objective information of subjects' past medical history, health status, health related behavior, and income affecting purchase of PHI and utilization of healthcare services. And the efforts of controlling the endogeneity of medical use and health insurance with latent variables which affect the decision on medical use and health insurance, are very considerable.

      • KCI등재
      • KCI등재

        Sport referees’ career commitment as a mediator between quality of work life (QWL) and turnover intent

        김승모,Wai Chi Yip 국민체육진흥공단 한국스포츠정책과학원 2018 International Journal of Applied Sports Sciences Vol.30 No.2

        Referees as facilitators or conductors of every game play an extremely critical role in sports because they are one of the most important elements in providing pleasant and fair experiences to participants, spectators, and others in sporting events (Cuskelly & Hoye, 2013; Grunska, 2002). Referees’ role becomes even more significant in sanctioned, formal, or important competitions (Yip, Kim, & Love, 2017). To smoothly manage each game, referees should have not only sufficient knowledge of the rules and regulations of their sport but also a correct understanding of the aims of each event based on the level of competition so that they can adopt an appropriate standard in officiating in line with those aims. For instance, the objectives and values of recreational sports are fun, a healthy lifestyle, and skill development through sport participation rather than winning, which is the most highly valued element in competitive sports (Chelladurai & Kerwin, 2017). Therefore, referees’ approach to recreational sports should focus more on positive sport experiences and enjoyment than on winning. Sport officiating is a challenging and demanding task performed under great stress because referees are expected to continuously make correct, safe and fair judgments of every individual play during a match (Kim, 2017; Yip et al., 2017). Since referees are well aware of how important their calls are in a game, they make great efforts to remain focused on each play to meet these expectations. However, it is almost impossible for them to perform perfectly with no mistakes during every competition. Although bad calls unwittingly made by referees are often accepted as part of a game, it is not uncommon to see fans and media criticizing and blaming bad calls that may actually have altered the outcome of a match, which could ultimately intensify the stress and pressure on referees (Folkesson, Nyberg, Archer, & Norlander, 2002; Parsons & Bairner, 2015). Infuriated critics often go beyond merely blaming referees for bad calls. Players and coaches often verbally abuse and even physically attack referees when the players and coaches do not agree with their calls. For instance, soccer players who were angry about being shown a red card killed referees during amateur soccer matches in Argentina and Mexico in 2016 (Couzens, 2017; Gibson, 2016).

      • KCI등재

        사염화탄소의 장기(長期) 투여(投與)로 유발된 백서(白鼠) 간경변(肝硬變)에 대한 형방지황탕(荊防地黃湯)의 조직병리학적 영향

        김승모,Kim, Seong-Mo 대한한방내과학회 2008 大韓韓方內科學會誌 Vol.29 No.2

        Objective : This study was carried out to investigate the effects of oral administration of Hyeungbangjihwang-tang (HBJHT) on the liver cirrhosis of rats induced by Carbon tetrachloride for 10 weeks. Method : The histopathological changes were observed. The HBJHT extracts were daily dosed at 50, 100 and 200mg/kg for 12 weeks. Results : Severe hepatocellular necrosis and ballooning, hyperplasia of connective tissue, subdued reduction of hepatic lobule, and hyperplasia of bile duct in portal triad were dramatically decreased in the HBJHT-treated group compared to that of the Carbon tetrachloride-treated control group in histopathological observation. The diameter of hepatic lobules was significantly enlarged in the HBJHT-treated group compared to that of the Carbon tetrachloride-treated control group, and the amounts of connective tissue, degenerative cells and bile ducts were significantly and dose-dependently decreased. Conclusion : It is concluded that HBJHT has a significant recovering effect on the liver of rats induced by carbon tetrachloride.

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