Holoprosencephaly 1례

김노현,박상조,황태규,이순용 인제대학교 1993 仁濟醫學 Vol.14 No.2

Holoprosencephaly는 대뇌 반구 발달의 실패와 중앙선상의 안면기형을 나타내는 드문 선천성 질환이다. 저자들은 출생시 토순 및 비정상적인 안면소견을 보여 시행한 전산화 단층촬영에서 Alobal type으로 확진된 환아를 경험하였기에 보고하고자 한다. Holoprosencephaly is the result of an embryogenic defect of prechodal mesoderm which leads to incomplete morphogenesis of the fore brain and variable deficit of facial midline anomalies. A case of holoprosencephaly, alobal type with premaxillary agenesis in 1-day-female patient was presented. She had hypotelorism, cleft upper lip, and flat nasal bridge. Diagnosis of holoprosencephaly is confirmed by clinical features and CT-scan. A brief review of literatures was made.

쌍구형 회전교차로 도입에 따른 운영효과 연구

김노현,김명수 한국ITS학회 2017 한국ITS학회논문지 Vol.16 No.6

본 연구는 대전광역시 중구에 위치한 대고오거리와 성모오거리를 대상으로 회전교차로 도입 시 나타나는 효과에 대하여 미시적 교통시뮬레이션 프로그램인 VISSIM을 이용하여 분 석하였다. 분석결과 기존 교차로의 구간 별 평균 통행속도는 31.51km/h로 분석되었으며, 평균 지체 시간은 32.5초로 분석되었다. 대고오거리만 회전교차로로 전환시 평균 통행속도 35.04km/h, 평균 지체시간 24.5초로 분 석되었고, 성모오거리만 회전교차로로 전환될시 구간별 평균 통행속도는 34.79km/h, 지점별 평균 지체시간은 28.0초로 분석되었다. 마지막으로 대상지 2개 지점을 쌍구형 회전교차로로 전환 될 시의 구간 별 평균 통행속도는 38.62km/h, 지점별 평균 지체시간은 20.4초로 분석되 었다. 이와 같이 두 개 교차로를 각각 회전교차로로 전환하는 시나리오에서 지체시간이 감소 하는 것으로 나타났고, 두 개 지점을 모두 회전교차로로 연결하는 쌍구형 회전교차로 전환 시 지체시간이 가장 적게 나타나 기존 교차로에 비해 효율적이라고 판단되었다. This was a study on the ultimate effect and characteristics of introducing a roundabout through a review of literature on the subject of roundabout. In order to examine an effect produced when roundabout is substituted for ordinary signal-controlled intersection operated at Daego Five-way Intersection and Seongmo Five-way Intersection located in Junggu, Daejeon Metropolitan City, site to be studied, the produced effect was analyzed through comparison between before and after introducing roundabouts in series at Daego Five-way Intersection and Seongmo Five-way Intersection by using microscopic traffic simulation program VISSIM widely used for analyzing an effect of roundabout based on a survey of geometric structure, traffic volume and signal interval on the site. As mentioned above, when Daego Five-way Intersection and Seongmo Five-way Intersection was changed to roundabout, a positive effect was produced on average speed and delay time in comparison with the existing status. It is possible to expect that roundabout can be more efficiently operated when 2 places on the site are changed to double roundabout than when separately changed to roundabouts.

국어과 성적평가에 있어서의 선택형 평가와 서답형평가의 비교연구

김노현 ( No Hyeon Kim ) 한국어교육학회 1966 국어교육 Vol.- No.12

영아연축의 임상양상 및 ACTH 치료효과에 관한 고찰

김노현(No Hyun Kim),황태규(Tae Gyu Hwang),이순용(Soon Yong Lee) 대한소아신경학회 1993 대한소아신경학회지 Vol.1 No.2

The anticonvulsant effect of ACTH in the treatment of infantile spasms has been well documented. But the principal mechanism of ACTH, duration of therapy and dosage are still controversial. The authors made a comparative study with the type of disease, time of treatment and therapeutic dosage for the effectiveness of ACTH therapy. The results were as follows: 1. Six cases(23%) were in cryptogenic group and nineteen cases(77%) were in symptomatic group. There was no significant statistical difference between two groups in treatment outcome(p>0.25). 2. Early treatment group with treatment within 4 weeks after onset included 14 patients(54%), while late treatment group with treatment after 4 weeks of onset included 12(46%). There was no significant statistical difference in effectiveness of ACTH therapy between them(p>0.25). 3. High dose group(above 100U/M/day) included 9 patients(35%), while low dose group(below 100U/M/day) included 17 patients(65%). In high dose group, ACTH therapy was more effective than low dose group(p<0.05).

2014 인천장애인아시아경기대회 및 2018 평창동계패럴림픽 선수촌 병원 내 한의진료소 내원환자 고찰

김노현(No Hyeon Kim),기유미(Yu Mi Gi),김태규(Tae Gyu Kim),조후인(Hu In Cho),최종호(Jong Ho Choi),신정미(Jung Mi Shin) 대한스포츠한의학회 2018 대한스포츠한의학회지 Vol.18 No.1

Objectives The purpose of this study was to analyze characteristics of patients who visited Korean medicine clinic at 2014 Incheon Asian Para Games and 2018 Pyeong-chang Winter Paralympics. Methods 517 cases (322 first visit and 195 reuse) of Incheon and 201 cases (91 first visit and 110 reuse) of Pyeong-chang were investigated. Results & Conclusions 1. The rate of patients who had experienced acupunture treatment were 62.1%(Incheon) and 72.5%(Pyeong-chang). 3. The rate of patients with injury were 92.9%(Incheon) and 89.0%(Pyeong-chang). 4. Low back, neck, shoulder were most 3 parts of injury. 5. The average number of reuse per a patient were 1.88±1.259(Incheon) and 2.50±2.473(Pyeong-chang). 6. The satisfaction of treatment was 4.86±0.349 in Pyeong-chang.

5지회전교차로 운영에 따른 교통개선방안에 관한 연구

김명수,김노현,김예지 대한교통학회 2017 대한교통학회 학술대회지 Vol.76 No.-

회전교차로는 교차로 내에 위치한 중앙교통섬을 중심으로 하여 시계반대방향으로 차량이 운행되며 진입 차량은 회전 중인 차량에 양보하는 것을 기본원리로 하는 평면형 교차로이다. 해외 교통선진국에서는 회전교차로의 우수성이 인정받아 활성화 되어 있으며 최근 우리나라에서도 해외에서 증명된 회전교차로의 긍정적인 효과를 인지하고 2004년에 국토교통부에서 회전교차로 설계지침을 발표하였다. 한국교통연구원 회전교차로 정책연구 지원사업 조사에 따르면 시범사업동안 설치된 회전교차로를 도입 전·후의 조사결과 교통사고, 지체시간, 통행속도 등에서 일반 평면교차로로 운영되었을 때보다 긍정적인 효과를 보였으며 이번 연구에서는 일반적인 3,4지 회전교차로가 아닌 5지교차로를 주제로 미시적 교통프로그램 VISSIM을 이용하여 연속적인 회전교차로의 도입 전·후를 비교 후 나타나는 효과에 대해 분석하는 것을 목적으로 한다.

Establishment and Selection of Indicator Materials for Cervi Parvum Cornu Pharmacopuncture

양규진,이기범,김노현,김태규,기유미,주환수,서창용,이인희,정화진,하인혁,이재웅 대한침구의학회 2017 대한침구의학회지 Vol.34 No.4

Background: Recently, Cervi Parvum Cornu pharmacopuncture has been widely used. But no studies on the indicator materials for Cervi Parvum Cornu pharmacopuncture have been conducted. The aim of this study was to select indicator materials that would aid in the uniform preparation of standardized Cervi Parvum Cornu pharmacopuncture. Methods: Three lots of Cervi Parvum Cornu pharmacopuncture were analysed. Each lot was prepared using the same methods and materials. Chondroitin sulfate, alanine, and leucine were selected as the indicator materials for Cervi Parvum Cornu. For standardization, chondroitin sulfate analysis was performed using the colorimetric method, while alanine and leucine were analyzed using liquid chromatography–mass spectrometry (LC–MS). Results: Analysis of the three lots of Cervi Parvum Cornu pharmacopuncture found chondroitin sulfate levels of 108.9 ± 17.3 ug/ml, 118.8 ± 5.0 ug/ml and 112.3 ± 11.9 ug/ml. Alanine levels were 44.9 ± 2.8 ug/ml, 44.6 ± 0.3 ug/ml, and 43.9 ± 0.2 ug/ml. Leucine levels were 29.6 ± 0.7 ug/ml, 29.0 ± 0.1 ug/ml, and 29.4 ± 0.1 ug/ml. Conclusion: These results suggest that chondroitin sulfate, alanine, and leucine may be useful for the standardization of Cervi Parvum Cornu pharmacopuncture.

복합부위통증증후군의 침구치료 효과에 대한 연구동향 고찰

김호선,배영현,김해솔,서창용,김노현,양규진,이기범 대한침구의학회 2016 대한침구의학회지 Vol.33 No.4

A Review of Research on the Effects of Acupuncture and Moxibustion Treatment to Complex Regional Pain Syndromes Ho Sun Kim1,2,*, Young Hyun Bae1, Hae Sol Kim1, Chang Yong Suh1, No Hyeon Kim1, Kyu Jin Yang1 and Gi Bum Lee1 1Department of Acupuncture and Moxibustion Medicine, Gang-Nam Jaseng Hospital 2Department of Science in Korean Medicine, Graduate School, Kyung Hee University Objectives : This study was performed to review articles concerning acupuncture or moxibustion treatment for Complex Regional Pain Syndromes. Methods : On-line databases including PubMed, Cochrane Library, Ovid-EMBASE, NDSL and OASIS were searched to find articles concerning acupuncture or moxibustion treatment for Complex Regional Pain Syndromes. Several overlapping articles and those not relevant to the topic were excluded, as well as review articles and commentaries. Results : 16 case reports were selected through the procedure, all of which presented successful treatment cases of Complex Regional Pain Syndromes with acupuncture and moxibustion. Most of them presented one single patient case and were published in Korea. However, almost half of them were printed in English, and had been continuously published since 2005. It was remarkable that pharmacopuncture was predominantly used to treat Complex Regional Pain Syndromes. Also, we noted that Chinese scalp acupuncture needs to be studied further as two successful cases were presented from the U.S army. Conclusion : The results show that several case reports have been published regarding Complex Regional Pain Syndromes treated with acupuncture and moxibustion. However, all of them were case reports which are given low status in Evidence-Based Medicine. We expect that a more diverse range of articles, including case control studies, cohort studies and randomized controlled trials will be performed in the near future, and that a unified outcome measure will be developed for Complex Regional Pain Syndromes.

청소년기 요추간판탈출증에 대한 한방 보존적 치료 12례의후향적 분석

김해솔,배영현,김호선,서창용,김노현,이기범,양규진 대한침구의학회 2016 대한침구의학회지 Vol.33 No.1

Objectives : This study was performed to assess the effectiveness of conservative Korean traditional medical treatment on lumbar intervertebral disc herniation in 12 adolescents. Methods : Data were collected from adolescent patients diagnosed with lumbar intervertebral herniation by MRI, hospitalized at Jaseng Korean Medicine Hospital from January 1, 2014 to December 31, 2015. A total of 12 patients were included in the study. Patients were treated by acupuncture, pharmacopuncture, electroacupuncture, herbal medicine, chuna manual therapy, physical therapy during hospitalization period. To measure treatment outcomes, a verbal numerical rating scale (VNRS), Oswestry disability index (ODI), range of motion (ROM), Straight leg raising test (SLR), and EQ-5D were used. Results : The average age of the participants was 16.05±1.62. The average of duration of symptom was 19.25±26.83 (weeks) and the average length of hospitalization was 23.8±16.4 (days). 2 patients (17 %) suffered from only lumbar pain, while 10 patients (83 %) suffered from lumbar and leg pain. No participant suffered from only leg pain. 8 patients (67 %) were diagnosed with disc herniation in one segment, and 4 patients (33 %) were diagnosed with disc herniation in multiple segments. A total of 17 disc segments (28 %) were herniated. The most herniated lumbar level was L4-5. 3 segments were diagnosed with bulging (17 %), 6 with protrusion (35 %), and 8 with extrusion (47 %). Extrusion was the most frequent herniated type. After treatment, the average VNRS of lumbar pain significantly decreased from 5.58±1.62 to 2.91±1.56 (p<0.001) and the average VNRS of leg pain significantly decreased from 5.16±2.51 to 3.08±1.8 (p<0.001). ODI significantly decreased from 48.87±18.72 to 28.57±15.05 (p<0.05), and EQ-5D significantly increased 0.58±0.31 to 0.80±0.12 (p<0.05). Range of flexion significantly improved from 61.25±32.62 to 68.33±26.22 (p<0.05). Conclusion : Conservative Korean Traditional Medical Treatment may be effective in the treatment of lumbar intervertebral disc herniation in adolescence. However, more case reports and clinical research are needed.

경항통에 대한 추나요법의 효과: 체계적 문헌고찰과 메타분석

이기범,하인혁,김호선,배영현,김노현,서창용,양규진,정유화,소민지,이윤재,Lee, Ki-Beom,Ha, In-Hyuk,Kim, Ho-Sun,Bae, Young-Hyun,Kim, No-Hyeon,Suh, Chang-Yong,Yang, Kyu-Jin,Jung, You-Hwa,So, Min-Ji,Lee, Yoon-Jae 척추신경추나의학회 2016 척추신경추나의학회지 Vol.11 No.2

Objectives : To determine the effectiveness of Chuna manual therapy for neck pain Methods : We searched 7 electronic databases(OASIS, NDSL, Ovid-MEDLINE, Ovid-EMBASE, Cochrane library, AMED, CNKI) to find all Randomized controlled trials that used Chuna manual therapy as a treatment for neck pain. The methodological quality of each RCT was assessed by the Cochrane risk of bias tool. Results : 7 RCTs met our inclusion criteria. The meta-analysis of 7 studies showed favorable results for the use of Chuna manual therapy. High risk of bias were observed for performance bias and detection bias. Conclusions : Our systematic review found favorable results using Chuna manual therapy for neck pain. But there are several limitations in our study due to lack of well-designed RCT. To obtain stronger evidence, further clinical trials would be needed.