Trabecular Bone Score and Central Quantitative Computed Tomography for the Prediction of Vertebral Fragility Fractures in Postmenopausal Women

김근영,전윤경,고태식,김인주,김근영 대한골대사학회 2023 대한골대사학회지 Vol.30 No.1

Background: We aimed to investigate whether densitometry results and volumetric bone mineral density (vBMD) can predict vertebral fragility fractures (VFF) in postmenopausal women. Methods: We enrolled 271 postmenopausal women aged >45 years who visited our hospital for health check-ups between September 2016 and September 2017. The lumbar spine (LS) and femoral neck (FN) densitometry results and trabecular bone score (TBS) were calculated using dual energy X-ray absorptiometry. vBMD was assessed using central quantitative computed tomography (cQCT). Baseline and follow-up X-ray images were reviewed to evaluate thoracolumbar vertebral compression fractures (CFs), according to the Genant criteria. Results: At baseline, 76 patients (28.0%) had CF. Additional or progressive fractures were noted in 26 participants (9.6%) with a median follow-up of 19.5 months. The median TBS and cQCT were significantly higher in participants without baseline CF than those with baseline CF (P<0.001). During the follow-up, Kaplan–Meier analysis showed that T-scores of the LS and FN <-2.5, degraded microarchitecture based on the TBS (≤1.200), and vBMD <80 mg/cm3 was significantly associated with future osteoporotic CF. The final multivariate Cox regression analysis showed that baseline CF and low TBS and vBMD were significant risk factors for future VFF. Conclusions: Participants with baseline CF and degraded microarchitecture had higher CF predisposition. Moreover, cQCT can predict future vertebral fractures.

우리나라의 지역 특성이 지역 경제 성장에 미치는 요인과 영향 분석

김근영,Kim, Geunyoung 인천대학교 도시과학연구원 2020 도시과학 Vol.9 No.1

This study analyzed the factors affecting economic growth using multiple regression model and Geographically Weighted Regression in consideration of population, industry and employment, housing and political characteristics on economic growth by region. The analysis results are summarized as follows. First, the total employment growth rate, manufacturing employment growth rate, local election turnout and the level of party consensus between the central and local governments are having a positive impact on regional economic growth. Second, according to the GWR analysis, the population has a positive impact on economic growth in the southern region of Korea, and the increase in the total number of employees has a positive impact on the southern region of Gyeonggi Province, Gangwon Province, North Chungcheong Province and North Gyeongsang Province. Finally, the voter turnout of urbanites is positively affecting economic growth in South Chungcheong Province, Gangwon Province and the southern coast, while North Jeolla and South Jeolla provinces have a positive impact on economic growth as the parties of the central and local governments are equal. The results of this study may suggest the role of local government for regional economic development.

대도시권 시대의 도시정책을 위한 기초지자체 유형 구분

김근영,Kim, Geunyoung 인천대학교 도시과학연구원 2020 도시과학 Vol.9 No.2

The purpose of this study is to present a plan to distinguish 229 local governments nationwide by taking into account various characteristics such as population, employment, housing, and industry of the region for customized urban policies in the era of metropolitan areas. The National Statistical Portal (KOSIS) collected and standardized data related to population, housing, industry, and finance by region from 2000 to 2015 for the classification of regional types necessary for customized urban policies, and this was used to classify them into regional types that considered population, employment, housing and industry. The summary of the analysis results is as follows. First, as a result of the regional type classification, 10 key employment sites (4.4%), 5 employment centers (2.2%), 38 residential centers (16.6%), 20 growth areas (8.7%), 26 industrial cities (11.4%), 35 low-fertile farming and fishing villages (15.3%) and 95 stagnant areas (41.5%). Second, the Seoul metropolitan area is the most diverse type of metropolitan area in the country, with most of its core employment sites inside Seoul, residential centers inside and outside Seoul, and growth areas in the southeastern part of the country (Busan, Ulsan, and Gyeongsangnam-do) are mixed with industrial and growth areas centered around Busan, Ulsan and surrounding areas, while the rest of the local governments are found to be low-fertile farming villages or stagnant areas. Daegu (Daegu, Gyeongbuk) is an industrial city in Daegu, and the rest of the local governments are either low-density farming and fishing villages or stagnant areas. The Honam region (Gwangju and Jeolla) was found to be a low-mill farming and fishing village or stagnant area except for Gwangju, while the Chungcheong region (Daejeon, Sejong, and Chungcheong) was seen as a growth area with areas adjacent to Daejeon, Sejong, and the Seoul metropolitan area, and some industrial cities were included. Finally, the Gangwon area was mostly classified as low-density farming and fishing villages and stagnant areas.

家蠶의 바이러스成 軟化病에 관한 硏究 : Ⅱ.奬勵蠶品種의 原種에 대한 抵抗性 檢定 Ⅱ.Resistance to Flacherie and Densonucleosis Virus in the Parantal Lines of the Leading Silkworm Varieties in Korea

金槿榮,姜錫權,李載昌 한국잠사학회 1986 한국잠사곤충학회지 Vol.28 No.2

Resistance to the flacherie virus(FV) and the densonucleosis virus(DNV) of 10 Japanese lines and 10 Chinese lines used for hybrids was tested and the results obtained are as follows: 1. Hansaeng #1 showed the highest resistance to the FV among the tested Japanese lines whereas Mudeung was of lowest resistance. In Chinese lines tested on the resistance to the FV, Jam 118 was the higest while Jam 116 was the lowest. 2. In Japanese lines tested on the resistance to the DNV, it was shown that Jam 117. Gyeongchu, Mudeung, Hansaeng #1 and Hansaeng #3 were of the complete resistance but Jam 115 showed the lowest resistance. On the other hand, all the Chinese lines tested showed the complete resistance to the DNV.

Effects of Lead(IV) Acetate on Procoagulant activity in Human Red Blood Cells

김근영,Kyung-Min Lim,Jung-Hun Shin,Ji-Yoon Noh,Jae-Bum Ahn,Da-Hye Lee,정진호 한국독성학회 2009 Toxicological Research Vol.25 No.4

Lead (Pb) is a ubiquitously occurring environmental heavy metal which is widely used in industry and human life. Possibly due to a global industrial expansion, recent studies have revealed the prevalent human exposure to Pb and increased risk of Pb toxicity. Once ingested by human, 95% of absorbed Pb is accumulated into erythrocytes and erythrocytes are known to be a prime target for Pb toxicity. Most of the studies were however, focused on Pb2+ whereas the effects of Pb4+, another major form of Pb on erythrocytes are poorly understood yet. In this study, we investigated and compared the effects of Pb4+, Pb2+ and other heavy metals on procoagulant activation of erythrocytes, an important factor for the participation of erythrocytes in thrombotic events in an effort to address the cardiovascular toxicity of Pb4+. Freshly isolated erythrocytes from human were incubated with Pb4+, Pb2+, Cd2+ and Ag+ and the exposure of phosphatidylserine (PS), key marker for procoagulant activation was measured using flow cytometry. As a result, while Cd2+ and Ag+ did not affect PS exposure, Pb4+ and Pb2+ induced significantly PS exposure in a dose-dependent manner. Of a particular note, Pb4+ induced PS exposure with a similar potency with Pb2+. PS bearing microvesicle (MV), another important contributor to procoagulant activation was also generated by Pb4+. These PS exposure and MV generation by Pb4+ were well in line with the shape change of erythrocyte from normal discocytes to MV shedding echinocytes following Pb4+ treatment. Meanwhile, nonspecific hemolysis was not observed suggesting the specificity of Pb4+-induced PS exposure and MV generation. These results indicated that Pb4+ could induce procoagulant activation of erythrocytes through PS exposure and MV generation, suggesting that Pb4+ exposure might ultimately lead to increased thrombotic events.

다문화가정 연구개관과 향후 방향성

김근영,곽금주,배소영 한국심리학회 2009 한국심리학회지 일반 Vol.28 No.3

Many social scientists have shown keen interest in the way multi-cultural family members adjust themselves to live in Korea. The present study is designed to summarize recent research trends about multi-cultural families in Korea, to critically review contemporary studies' limitations, and to propose future topics for the next decade. Based on complete enumeration, it is suggested that more studies about father's contributions and about adolescent members are needed. Topics such as benefits of multi-cultural experiences, psychopathologies of immigrant members, and development of acculturation styles in Korea are also suggested for possible topics that have not been thoroughly investigated yet. Regardless of research topic, future studies should include Korean control groups in their research design, to warrant appropriate comparisons between immigrant families and native Korean families. 다문화가정 구성원이 우리 사회에서 어떠한 양상으로 살아가고 있는가에 관한 문제는 최근 심리학을 비롯한 국내 사회과학자들의 많은 관심을 끈 주제이다. 본 연구는 2000년대 발표된 다문화관련 심리학적 국내 연구들을 개관하고 이를 해외 연구들의 추세와 비교해 보며, 국내 다문화가정 연구들의 경향성을 통해 향후 대두될 연구주제를 제시하려는 목적으로 쓰여졌다. 국내 연구의 개관을 통해 현재 다문화 연구들에서는 특히 비교대상의 부재, 그리고 청소년 및 아버지를 포함한 연구대상의 부재가 두드러졌으며, 또한 다문화경험의 다양한 측면을 탐구하는 연구 및 다문화 구성원의 정신병리에 대한 연구도 부족한 실정으로 드러났다. 또 보다 심층적인 문화적응론에 대한 제시도 외국에 비해 많이 부족한 상황으로, 이들 주제가 미래의 다문화가정 연구의 핵심으로 떠오를 가능성이 높다는 점을 시사하였다.

AC(After Corona) 시대의 도시계획

김근영 (사)한국도시계획가협회 2020 Urban planners Vol.7 No.3

중부내륙고속도로 제9공구

김근영,이경래 대한토목학회 2002 대한토목학회지 Vol.50 No.7

Identifying Characteristics of Incidents at Hazardous Material Facilities

김근영,Kim, Sang Won,Won, Jai Mu 한국방재학회 2009 한국방재학회논문집 Vol.9 No.6

Safety and quality assessment systems are very important in manufacture, storage, transportation, and handling of hazardous materials(hazmat) to prevent hazmat disasters. At present, hazardous materials exist everywhere in our daily lives with various forms of plastics, household products of cleaning and washing detergents, fertilizers or petroleum-related products. However, hazardous materials are dangerous substances when they are released to human or environment. Hazardous materials become very widely used substances in the age of oil-based industrial economy. The Korean Ministry of Environment (KMOE) describes about one hundred thousand types of chemicals are produced and used worldwide. Over four hundred new chemicals are introduced in every year. A crucial question for the Korean hazardous material management may have been raised: Will you be safe from hazardous material incidents? The gas leak disaster at Union Carbide's Bhopal, India in 1984 that made over 6,400 people killed and 30,000 to 40,000 people seriously injured is the representative case for the safety of hazmat. Korea becomes vulnerable to hazmat disaster due to the development of high-tech industry. Thus, the risk assessment system is required to Korea for transferring abandoned hazmat management systems to self-correcting safety systems. This research analyzed characteristics of various hazmat incidents applying statistical analysis methods including frequency analysis or analysis of category data to hazmat incidents for ten years. All of three analyses of category data indicate the significance of causality between hazmat incident site groups and seasons, regional groups, and incident casualty groups.

Retroperitoneal Suppurative Fistula Caused by Remnant Suture Material in a Poodle Dog

김근영,이채영,김민연,최현종,홍정호,김효연,박효진,김나현,이동빈,이재훈 한국임상수의학회 2021 한국임상수의학회지 Vol.38 No.6

An eight-year-old, 3.4 kg, spayed female poodle dog was referred to Gyeongsang National University Animal Medical Center with obstinate bilateral retroperitoneal subcutaneous abscess. The medical history revealed ovariohysterectomy (OHE), lipoma, and mammary gland tumor excision performed two years ago. The dog presented with left retroperitoneal subcutaneous abscess discharge five months back and was treated by abscess drainage and antibiotics in a local veterinary hospital, but a relapse was reported on discontinuing antibiotics. On physical examination, the dog was febrile (40°C) and both retroperitoneal masses showed typical inflammatory reaction and purulent discharge. On serum chemistry analysis, hyperproteinemia, hyperglobulinemia, and elevated levels of C-reactive protein were observed. Cytologic examination showed degenerative neutrophils and phagocytic macrophages. Radiological examination revealed encapsulated hypoechoic subcutaneous masses in bilateral abdominal flank and the left flank mass was connected with the caudal pole of left kidney through fistula. Based on the diagnostic examination, exploratory celiotomy was recommended and left nephrectomy, and resection of bilateral masses were performed. During procedure, fistula between caudal pole of left kidney and left subcutaneous abscess was detected and suture material was identified. Resected tissue was histologically examined and diagnosed as suppurative abscess caused by the suture material. This case report describes chronic suppurative foreign body reaction including caudal pole of left kidney and bilateral retroperitoneal subcutaneous masses induced by the suture material used in OHE two years ago and the necessity of computed tomography examination to identify character of mass and extent of surgical resection.