단순진폐증에 대한 흉부 고해상 전산화 단층촬영의 진단적 의의

김경아,김지홍,장황신,안형숙,임영,윤임중,Kim, Kyoung-Ah,Kim, Hi-Hong,Chang, Hwang-Sin,Ahn, Hyeong-Sook,Lim, Young,Yun, Im-Goung 대한예방의학회 1996 Journal of Preventive Medicine and Public Health Vol.29 No.3

Early recognition of coalescence in pneumoconiotic lesions is important because such coalescence is associated with the respiratory symptoms and deterioration of lung function. This complicated form of pneumoconiosis also has worse prognosis than does simple pneumoconiosis. High resolution computerized tomography(HRCT) provides significant additional information on the stage of the pneumoconiosis because it easily detects coalescence of nodules and emphysema that may not be apparent on the simple radiograph. The purpose of this study is to clarify the role of HRCT in detection of large opacity and the relationship of change between the coalescence of nodules or emphysema and lung function in dust exposed workers. 1. There was good correlation between the HRCT grade of pneumoconiosis and ILO category of profusion. 5(9.09%) in 55 study population had confluent nodule extending eve, two o, more cuts on HRCT. HRCT could identify the pneumoconiotic nodules which was not found by simple radiogrphy in 6 workers with category 0/0. 2. No significant difference was observed coalescence of nodules and emphysema by dust type. 3. There was no significant difference in pulmonary function according to ILO and HRCT classification. 4. HRCT could detect the significant reduction in $FEV_1,\;FEV_1/FVC$, PEFR, $FEF_{25},\;FEF_{50},\;and\;FEF_{75}$ and remarkable increase in RV and TLC in study persons with emphysema compared with non-emphysema group. 5. Emphysema was found more often in nodules-coalescence group than small opacity group by HRCT. We found that HRCT could easily detect areas of coalescence and complicated emphysema compared to plain chest X-ray. Also our data suggest that it is primarily the degree of emphysema rather than the degree of pneumoconiosis that determines the level of pulmonary function.

수열 합성 공정 조건이 티탄산 납의 상 형성에 미치는 영향

김경아,김정석,천채일,Kim, Kyoung-A,Kim, Jeong-Seog,Cheon, Chae-Il 한국세라믹학회 2011 한국세라믹학회지 Vol.48 No.1

Lead titanate ($PbTiO_3$) powder was prepared from lead nitrate ($Pb(NO_3)_2$) and titania ($TiO_2$) by hydrothermal route. Phase formation process was investigated by observing the phases formed in various experimental conditions like different KOH concentration, reaction temperature and time. $PbTiO_3$ powder was fabricated when the KOH concentration was 0.8M or higher. An intermediate compound, $PbTi_{0.8}O_{2.6}$, was formed at first by a reaction between PbO and $TiO_2$ and changed into $PbTiO_3$ powder with a perovskite crystal structure. A $PbTiO_3$ phase was formed in a shorter time when a KOH concentration was increased from 0.8M to 8M because a driving force for a $PbTiO_3$ formation was increased due to an increase in a degree of supersaturation. And $TiO_2$ (rutile) and $3PbO{\cdot}H_2O$ were observed at room temperature in a 0.8M KOH solution and $TiO_2$(rutile) and PbO (litharge) in a 8M KOH. A $PbTiO_3$phase was also formed in a shorter time at a higher reaction temperature as a reaction temperature influenced the rates for a dissolution and a precipitation.

PM2.5로 자극한 폐상피세포의 $NF{\kappa}B$ 활성화에 NO의 역할

김경아,남혜윤,문제혁,정진숙,임영,Kim, Kyoung-Ah,Nam, Hae-Yun,Mun, Je-Hyeok,Jeong, Jin-Sook,Lim, Young,Kai, Hirofumi 대한결핵및호흡기학회 2002 Tuberculosis and Respiratory Diseases Vol.52 No.6

연구배경 : PM2.5는 호흡기질환의 악화 및 호흡기 질환에 의한 사망률과 밀접하게 관계가 있다. PM2.5에 의한 호흡기 염증반응의 악화가 그 원인으로 생각되나 염증반응의 조절기전은 확실하지 않다. 본연구에서는 PM2.5에 의한 폐장의 염증반응을 조절하는데 중요한 역할을 하는 전사인자인 $NF{\kappa}B$의 활성화 기전을 알아보아 염증 조절기전에 대한 이해를 높이고자 시도되었다. 방 법 : 폐상피세포주인 A549 세포에서 PM2.5 자극에 의한 $NF{\kappa}B$의 활성화 및 ROS, 그리고 RNS 분비를 관찰 하였다. iNOS 억제제인 L-NIL가 $NF{\kappa}B$ 활성화에 미치는 영향을 관찰하였다. 결 과 : PM2.5는 A549 세포에서 $NF{\kappa}B$의 활성화를 유도 하였다. PM2.5로 A549 세포를 자극시 즉각적인 RNS의 분비는 관찰되었으나 명확한 ROS의 증가는 관찰되지 않았다. RNS 억제제인 L-NIL 처리시 $NF{\kappa}B$ 활성화는 억제되었다. 결 론 : A549 세포에서 PM2.5에 의하여 유도된 즉각적인 $NF{\kappa}B$ 활성화 과정에는 RNS가 중요한 역할을 할 것으로 생각된다. Background : The present study was performed to further improve our understanding of molecular mechanisms involved in the activation of NFkB, a major transcriptional factor involved in the inflammatory response in the lung, by particulate matter in lung epithelial cells with an aerodynamic diameter of less than $2.5{\mu}m$(PM2.5). Materials and Methods : Immediate production of reactive oxygen species (ROS) and nitrogen species (RNS), with the PM2.5 induced expression of inducible nitric oxide synthase (iNOS), $I{\kappa}B$ degradation and $NF{\kappa}B$-dependent transcriptional activity, in 549 cells, were monitored. Addition, we also examined the effect of the iNOS inhibitor, L-N6-(1-iminoethyl) lysine hydrochloride (L-NIL), on the PM2.5-induced $NF{\kappa}B$ activation in A549 cells. Results : The rapid degradation of $I{\kappa}B$ and the increase of transcriptional activity of the $NF{\kappa}B$-dependent promotor were observed in A549 cells exposed to PM2.5. The immediate production of ROS in response to PM2.5 in A549 cells was not clearly detected, although immediate responses were observed in RAW264.7 cells. A 549 cells, cultured in the presence of PM2.5, produced an increase in NO, which was noticeably significant after 15 min of exposure with the expression of iNOS mRNA. The addition of L-NIL, an iNOS inhibitor, significantly inhibited the PM2.5-induced $I{\kappa}B$ degradation and the increase of the $NF{\kappa}B$-dependent transcriptional activity. Conclusion : These results suggest that PM2.5 stimulates the immediate production of RNS, leading to the activation of $NF{\kappa}B$ in the pulmonary epithelium.

소아물리치료사와 소아작업치료사의 보조공학 활용 수준 및 자신감

김경아,정동훈,Kim, Kyoung-A,Jeong, Dong-Hoon 대한물리치료학회 2013 대한물리치료학회지 Vol.25 No.1

Purpose: This study sought to identify the utilization and confidence in assistive technology (AT) for pediatric physical therapists (PPTs) and pediatric occupational therapists (POTs) for the purpose of improving the utilization of AT in clinics. Methods: The subjects of this study were 167 therapists (98 PPTs and 69 POTs) who work at general hospitals, welfare centers, facilities for the disabled, and special education schools in Seoul and Gyeonggi province. The frequency analysis and chi-squared test were used. Results: This study found that both PPTs and POTs recognize that AT benefits infants with disabilities; however, they show low confidence in using AT. Applications of AT are concentrated on wheelchairs for mobility and assistance with seating position, with orthotics/prosthetics for both purposes. POTs were found to use a wider variety of AT devices. While both PPTs and POTs frequently select/recommend devices, both groups are less involved with delivery methods, manufacture of devices, and education on AT use. Conclusion: These findings show the actual conditions of utilization and confidence in AT of PPTs and POTs deeply involved with AT, and emphasize that AT training is essential for pediatric treatment by comparing domestic and foreign studies.

원발성 부갑상선항진증에 의한 악골의 다발성 갈색종양

김경아,고광준,Kim, Kyoung-A,Koh, Kwang-Joon 대한영상치의학회 2010 Imaging Science in Dentistry Vol.40 No.3

Brown tumor is usually diagnosed at the terminal stage of hyperparathyroidism. Diagnosis of this tumor is confirmed by endocrinologic investigations along with clinical and radiographic examination. Radiographical differential diagnosis of this tumor includes central giant cell granuloma, aneurysmal bone cyst, metastatic tumor, multiple myeloma, and Paget disease. This report presents a rare case of multiple brown tumors occurring at the maxilla and mandible, which was initially misdiagnosed as central giant cell granuloma. Plain radiographs demonstrated multiple well-defined multilocular radiolucency. CT images showed soft tissue mass with low attenuated lesions, perforation of the lingual cortical plate, and a heterogeneous mass at the right thyroid lobe. These findings were consistent with parathyroid adenoma. The patient had hypercalcemia, hypophosphatemia, and elevated alkaline phosphatase level. Surgical excision of the tumor was performed. No recurrence was observed during a 28-month follow-up.

경기 지역 대기 오염 농도의 시간 변동성과 관련된 종관 기상 상태의 전개

임규호(Gyu-Ho Lim),김경아(Kyoung-A Kim) 한국기상학회 1996 Asia-Pacific Journal of Atmospheric Sciences Vol.32 No.1

폐암에서 혈중 Cyfra 21-1, SCC 항원 및 CEA의 진단적 유용성

김경아 ( Kyoung Ah Kim ),이미화 ( Me Hwa Lee ),고윤석 ( Youn Suck Koh ),김선희 ( Seon Hee Kim ),임채만 ( Chae Man Lim ),이상도 ( Sang Do Lee ),김우성 ( Woo Sung Kim ),김동순 ( Dong Soon Kim ),김원동 ( Won Dong Kim ),문대혁 ( Dae H 대한결핵 및 호흡기학회 1995 Tuberculosis and Respiratory Diseases Vol.42 No.6

현대섬유미술에 나타난 재료 연구- 신체이미지를 중심으로-

김경아 ( Kyoung Ah Kim ) 한국기초조형학회 2014 기초조형학연구 Vol.15 No.1

문화라는 테두리 안에 들어오는 모든 창작영역에서 몸은 표현하고자하는 대상이자 표현주체로서 존재해왔다. 동서고금을 막론하고 인간의 끊임없는 창작주제중 하나는 바로 우리의 몸이다. 현대섬유미술에서도 신체는 여러 작가들에 의해 지속적으로 표현되어 왔다. 최근의 현대섬유예술에 대한 연구는 작품주제가 어떠한 제작과정을 거쳐 조형 작품으로 표현되는지에 대한 연구가 주를 이루었고 섬유라는 재질적 특성상 재료와 기법중심으로 분석이 이루어졌다. 본 연구에서는 특히 작품주제인 몸에 대한 이론적 배경을 중심으로 주제와 재료의 조형적 특징과의 관계성을 발견하여 섬유미술에 적용 가능한 조형분석연구 방법론을 제시하고자한다. 이를 위한 이론적 배경으로 먼저, 섬유조형에 대한 조형적 배경 및 특징과 신체에 대한 미학적 배경을 고찰 하였다. 또한 섬유미술에서의 재료에 대해서는 현대섬유작품에서의 재료 활용 현황을 국내외 작가 173명의 작가 작품을 대상으로 분석해보았다. 이를 바탕으로 신체를 표현한 국내외 섬유예술가 6명의 표본작품들의 재료적 특징과 조형성과의 관계성을 찾아내고자 하였다. 이에 따라 본 연구의 결과는 다음과 같다. 첫째, 작품의 신체에 대한 미학적 분석이 작품의 조형성 및 재료 선정 및 표현방식에도 영향을 준다. 둘째, 섬유미술에서의 재료사용시 근원적 다양함 보다는 표현하고자 하는 작가의 컨셉이 재료의 재질적 특징을 만들어 낸다는 것이다. 이러한 결과는 섬유작품에 대한 깊이 있는 이해와 다각적인 조형분석연구의 가능성을 시사하고 있다. The body has always existed as an object that people want to express and as a subject of expression in all creative areas within the boundaries of culture. In all ages and countries, one of the creative themes has been the human body. In contemporary textile art, the body has been a subject of expression by several artists. In this study, a modeling analysis research methodology differentiated in textile art is presented while investigating the relationships between the formative characteristics of the topics and textile materials, focusing especially on a theoretical background of the body. For the theoretical background, first of all, the historical background and characteristics of fiber molding and the aesthetic backgrounds of the body were investigated. In addition, the textile materials used in the works of 173 domestic and international contemporary textile artists were analyzed in order to investigate the status of materials utilized. Also, based on this, the relationship of material properties to plasticity in sample works of six domestic and international textile artists expressing the human body was investigated. The results of this study are as follows: First, the aesthetic analysis of the body of the work influences the plasticity of the work, the selection of materials, and method of expression. Second, when choosing materials, the characteristics of the material were produced based on the concept of the work according to the artists` intention rather than on underlying diversity. These results promote a deep understanding of the work of textile art and suggest the possibility of multifaceted formative analysis.

Magnetic and Structural Properties of Mg(Fe2-xAlx)O4 Thin Films

Kyoung Sun Kim,Seung Ho Han,Ho Gi Kim,Young Taek Lee,김경아,김정석,Chae Il Cheon 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.54 No.2

The magnetic and the structural properties of Mg(Fe2-xAlx)O4 thin films prepared by using the sol-gel method were investigated. The Mg(Fe2-xAlx)O4 thin films crystallized into the single spinel phase in air and the crystallization temperature increased from 500℃ (x = 0) to 800℃(x = 2) with increasing Al content x. The lattice constant and the grain size was decreased when the Al content increased in the Mg(Fe2-xAlx)O4 thin films annealed at 800℃. The Mg(Fe2-xAlx)O4 thin films with x ≤ 1.2 had Neel temperatures (TN) higher than room temperature while the thin films with x ≥ 1.6 lost ferrimagnetic ordering. The Mg(Fe2-xAlx)O4 thin films show the largest saturation magnetization (Ms) value of 87 emu/cm3 at x = 0.0 and the magnetization decreased with increasing Al content(x). The magnetic characteristics of the Mg(Fe2-xAlx)O4 thin films are discussed in terms of the cation distributions over the octahedral and the tetrahedral sites in the spinel structure. The magnetic and the structural properties of Mg(Fe2-xAlx)O4 thin films prepared by using the sol-gel method were investigated. The Mg(Fe2-xAlx)O4 thin films crystallized into the single spinel phase in air and the crystallization temperature increased from 500℃ (x = 0) to 800℃(x = 2) with increasing Al content x. The lattice constant and the grain size was decreased when the Al content increased in the Mg(Fe2-xAlx)O4 thin films annealed at 800℃. The Mg(Fe2-xAlx)O4 thin films with x ≤ 1.2 had Neel temperatures (TN) higher than room temperature while the thin films with x ≥ 1.6 lost ferrimagnetic ordering. The Mg(Fe2-xAlx)O4 thin films show the largest saturation magnetization (Ms) value of 87 emu/cm3 at x = 0.0 and the magnetization decreased with increasing Al content(x). The magnetic characteristics of the Mg(Fe2-xAlx)O4 thin films are discussed in terms of the cation distributions over the octahedral and the tetrahedral sites in the spinel structure.

만성요통환자에서의 통증신념과 우울, 통증생활방해와의 관계에서 대처전략의 매개효과

김경아(Kyoung-A Kim),추상희(Sanghui Chu) 한국콘텐츠학회 2017 한국콘텐츠학회논문지 Vol.17 No.10

본 연구는 만성 요통 환자의 통증 신념과 우울, 통증 신념과 통증생활방해 사이의 통증대처(능동적 대처와 수동적 대처)의 매개 효과를 확인하고자 하였다. 수집된 자료는 SPSS-WIN 21.0 프로그램으로, 다중매개 효과는 Indirect SPSS macro (Bootsrapping)를 사용하여 분석하였다. 분석결과 통증신념은 3.42 ± 9.67점이었고, 수동적 대처 29.68 ± 8.04점, 능동적 대처 25.49 ± 4.22점, 우울은 25.49 ± 11.56점, 통증생활방해는 46.94 ± 12.65점 이었으며, 이 5 가지 변수 간에 유의한 상관관계가 있었다. 만성요통 환자의 통증신념과 우울 사이에서 수동적 대처와 능동적 대처의 다중매개효과는 (b=.453, 95% CI=.228, .703)로 유의하였다. 통증신념과 통증생활방해에서 수동적 대처와 능동적 대처의 다중매개효과는 (b=.285, 95% CI=.131, .519)로 유의하였다. 능동적인 대처 전략은 통증 신념과 우울, 통증생활방해 사이의 관계에 긍정적인 중재 효과로 작용할 수 있음을 발견하였으며, 수동적 대처 전략은 부정적인 효과를 보임을 알 수 있었다. 따라서 만성 요통 환자를 대상으로 능동적 대처를 늘리는 대처 전략 프로그램이 필요하다. The Purpose of this study was to investigate of coping strategies(active and passive) between pain beliefs and depression, pain disability among chronic back pain patients. Data were analyzed by the SPSS-WIN 21.0 program. Indirect SPSS macro(Bootsrapping)was used to analyze the multiple-mediation model of this study. The result showed that the mean score for pain belief was 3.42±9.67, and he passive coping strategies was 29.68±8.04, active coping was 25.49±4.22. The mean score of depression was 25.49±11.56. The pain disability index was 46.94±12.65. It found that there were significant correlations among the 5 variables. The multiple mediated effects of passive coping and active coping on pain beliefs and depression were (b=.453, 95% CI=.228, .703) and on pain beliefs and pain disability were (b = .285, 95% CI = .131, .519) in chronic low back pain patients. This study discovered that the active coping strategies had a positive mediating effect in the relationship between pain beliefs and depression, pain beliefs and pain disability. And passive coping strategies had a negative mediating effect. Based on findings of this study, improving the active coping strategy programs or management is highly recommended in chronic back pain patients.