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김갑성,이승덕,이창환 대한한의학회 2006 대한한의학회지 Vol.27 No.4
Objective : Based on the immunological dysfunction in RA and the immunological feature of Clematis mandshurica Maxim. herbal acupuncture solution (CM-HAS), this study examined whether subcutaneous (s.c.) administration of CM-HAS has anti-inflammatory effects on adjuvant arthritis (AA) in the rat. Methods : Complete Freund's adjuvant was used to induce AA in rats. Secondary paw swelling of AA rats was measured, and polyarthritis index was scored. The administration of CM-HAS (2, 5, 10 mg/kg) to the Sinsu-hyul (BL 23) acupuncture point subcutaneously (s.c.) inhibited the inflammatory response and restored the weight of body and immune organs of AA rats. In this study, inhibitory effect of CM-HAS on cyclooxygenase-2 (COX-2) was evaluated. The plant material selected for this study has been used in Korean medicine for the treatment of various diseases that are considered as inflammatory in nature, e.g. asthma, arthritis, rheumatism, fever, edema, infections, snakebite and related inflammatory diseases. Results : There were significant secondary inflammatory reactions in AA rats, accompanied with the simultaneous decrease of body and immune organs weight. The administration of CM-HAS (2, 5, 10 mg/kg, s.c.) improved the above changes significantly. CM-HAS showed inhibitory activity against COX-2, which supports their traditional uses. In this study, aspirin and indomethacin were used to contrast with CM-HAS as the COX-2 inhibitors. Conclusion: The findings of this study may explain at least in part why CM-HAS has been traditionally used for the treatment of inflammatory conditions in traditional Korean and Chinese medicine. Objective : Based on the immunological dysfunction in RA and the immunological feature of Clematis mandshurica Maxim. herbal acupuncture solution (CM-HAS), this study examined whether subcutaneous (s.c.) administration of CM-HAS has anti-inflammatory effects on adjuvant arthritis (AA) in the rat. Methods : Complete Freund's adjuvant was used to induce AA in rats. Secondary paw swelling of AA rats was measured, and polyarthritis index was scored. The administration of CM-HAS (2, 5, 10 mg/kg) to the Sinsu-hyul (BL 23) acupuncture point subcutaneously (s.c.) inhibited the inflammatory response and restored the weight of body and immune organs of AA rats. In this study, inhibitory effect of CM-HAS on cyclooxygenase-2 (COX-2) was evaluated. The plant material selected for this study has been used in Korean medicine for the treatment of various diseases that are considered as inflammatory in nature, e.g. asthma, arthritis, rheumatism, fever, edema, infections, snakebite and related inflammatory diseases. Results : There were significant secondary inflammatory reactions in AA rats, accompanied with the simultaneous decrease of body and immune organs weight. The administration of CM-HAS (2, 5, 10 mg/kg, s.c.) improved the above changes significantly. CM-HAS showed inhibitory activity against COX-2, which supports their traditional uses. In this study, aspirin and indomethacin were used to contrast with CM-HAS as the COX-2 inhibitors. Conclusion: The findings of this study may explain at least in part why CM-HAS has been traditionally used for the treatment of inflammatory conditions in traditional Korean and Chinese medicine.
김갑성,조명승 대한금속재료학회(대한금속학회) 1968 대한금속·재료학회지 Vol.6 No.2
A feasibility study on sulfide mineral bearing iron ore from Yangyang iron mine was made to eliminate sulfur contents. The study indicated that by magnetic separation and flotation a portion of sulfide minerals could be removed. Magnetic separation, alone, was not amenable to eliminate effectively the sulfur contents to meet the iron ore concentrate specification. Petrographic examination showed that dendritical intrusion of sulfide minerals into magnetite grains needed fine grinding over 100 mesh for liberation.
An Economic Feasibility Study on Shiwha MTV project
김갑성,허재완,이영성 한국지역학회 2009 지역연구 Vol.25 No.2
The Shiwha Multi-Techono Valley (MTV) project is one of the controversial issues since it plans to be built on landfill areas while it destructs some of tidelands which should be conserved. A feasibility study is conducted for the purpose of giving a guideline to decision makers including NGO’s and a developer. NGO’s agree to implement the project since the environments quality in Shiwha is very serious and it should be improved. For improvement of environments in Shiwha, it costs at least 450 billion won which would be donated by a developer of the MTV project. We try to find an optimal size of development so that the destruction of tidelands is minimized as well as at least 450 billion won is secured. We analyzed an economic validation, estimated environmental and social impacts. As the benefits of the project, foreign currency income, income of employee, and environmental improvement effects are concerned, whereas construction expenses, environmental economic loss because of destruction of tidelands, and additional environmental pollution as the costs of the project. Various development scenarios are analyzed in order to find an optimal size of development and an optimal pattern of landuse. As a result, at least 3,300,000 m2 and the above should be developed in order to get an economic feasibility. As the size of the project increase, the B/C (Benefit to Cost) ratio is improved. Additionally, the ratio of green fields should be decreased in order to the developer secures 450 billion won for environmental quality of Shiwha.