경추에서 추체 골밀도와 골단판 두께가 압박력에 미치는 영향

권희,An, Howard S.,임태홍,전창훈 대한척추외과학회 1999 대한척추외과학회지 Vol.6 No.3

연구계획 : 경추 추간판 질환시 경추체간 골유합술 후 발생되는 골단판 침강의 원인과 정도를 조사하기 위해 신선 사체의 경추를 이용하여 골밀도 측정, 골단판 두께 측정 및 생역학적 조사를 하였다. 연구목적 : 경추의 골밀도와 골단판 두께가 압박력에 미치는 영향을 조사하고, 생역학적 측면에서 골단판 처리방법 을 재조명하여 환자의 선택과 수술 방법의 선택에 보다 나은 정보를 주고자 함에 있다. 대상 및 방법 : 7개의 신선 사체에서 C3에서 C7까지를 각각 박리하여 DEXA로 골밀도를, CT scan으로 골단판 두 께를 측정한 후 각 척추체를 상하로 분리하여 이들을 골밀도가 비슷하게 세 개의 군으로 나누었다. 1군은 골단판이 보존된 군, 2군은 골단판의 일부를 제거한 군, 3군은 골단판을 모두 제거한 군으로 나누어 MTS를 이용하여 압박실험을 하였다. 결과 : 골밀도와 골단판 파괴를 일으키는 압박력 사이에는 비례관계가 있었으나 골단판 두께와 골단판 파괴가 발 생되는 압박력 및 골밀도 사이에는 유의한 상호관계가 발견되지 않았다. 또한 1군이 3군보다 압박력에 견디는 힘이 유의하게 높았으나 1군과 2군, 2군과 3군 사이에는 유의한 차이가 없었다. 결론 : 술전 골밀도의 고려가 환자선택과 수술방법 선택에 중요할 것으로 생각되며, 골유합부의 침강을 줄이기 위 해 가능한 한 많은 골단판의 보존이 필요하리라 사료된다. Study Design : This is a biomechanical study to evaluate the subsidence at the cervical endplate from seven fresh cadavers. The study performed after evaluating a bone mineral density(BMD) and a thickness of the endplate. Objectives : To evaluate the effect of BMD and endplate thickness on the biomechanical strength in an anterior cervical interbody fusion model. Material and Methods : A total of 7 cervical spines(C3-C7) were obtained from fresh cadavers and dissected through the intervertebral disc to obtain the isolated vertebrae. BMD of each vertebral body was measured using a dual-energy x-ray absorptiometry(DEXA) and thickness of endplates was measured by CT images. Each vertebral body was cut into halves through the horizontal plane and prepared specimens were assigned one of the following 3 groups so that group mean BMDs became similar. In group 1, the endplates were preserved intact. The endplates in group 2 were burred into approximately 1/2 of the intact thickness. In group 3, the endplates were totally removed. Each specimen underwent the destructive compression test by using an Instron material test system(MTS). Results : There was significant linea relationship between BMD and load to failure. The load to failure of group 1 was significantly greater than group 3. Conclusion : Preoperative consideration of BMD would be important for patient selection and the choice of a surgical technique. And it may be important to preserve the endplate as much as possible to reduced the incidence of subsidence when performing the cervical interbody fusion.

지구성 운동과 순발성 운동에 있어서의 훈련효과의 대한 비교 연구

권희,심동원 대한스포츠의학회 1991 대한스포츠의학회지 Vol.9 No.1

콩트:여름날의 해후

권희 사회발전연구소 1995 한국인 Vol.14 No.8

척추 유합술에 이용된 자가골과 이종골 이식의 유합률 비교

권희,김부경,송준민,신병준,김연일,나수균 대한척추외과학회 1997 대한척추외과학회지 Vol.4 No.1

Study Design : This was a retrospective review. Thirty-seven consecutive patients were studied after thoracolumbar and lumbar posterolateral fusion using autograft of Lubboc to compare fusion rate, Clinical result, anesthetic time, blood loss and complications. Objective : To investigate the efficacy of Lubboc graft in the thoracolumbar and lumbar posterolateral fusion. Summary of Background Data : Previsional studies have reported that xenograft graft in the thoracolumber posterolateral fusion had poor fusion rate and clinical result. We analyzed Lubboc graft based on fusion rae, clinical result, anesthetic time, blood loss and complications. Methods : The authors had one retrospective analysis of 37 patients who were treated by posterolateral fusion with instrument from March 1993 to February 1995. Fusion was estimated by plain xray based on Brantigan classification and clinical result was analyzed with visual analogue scale. 37 patients were divied 3 group by graft material. Group I was consisted of 19 patients treated by posterolateral fusion with autograft, group Ⅱ was consisted of 5 patients treated by autograft and Lubboc, group Ⅲ was consisted of 13 patients treated by Lubboc. The authors analyzed fusion rate, clinical result, anesthetic time, blood loss and complications between each group. Results : The fusion rate of autograft(group Ⅰ) was 84%(16/19 cases), autograft and Lubboc(group Ⅱ) was 80%(4/5 cases), Lubboc(group Ⅲ) was 0%(0/13 cases). Clinical result were as follows : group Ⅰ is excellent-13 cases, good-3 cases, fair-3 cases, group Ⅱ is excellent-4 cases, poor-Ⅰ case and group Ⅲ is good-3 cases, fair-8 cases, poor-2 cases. Conclusion : Lubboc graft in posterolateral fusion of spine should be not recommanded due to the poor result. We recommand to mix autograft and Lubboc, when autograft is not suffcient

Spontaneously Reported Hepatic Adverse Drug Events in Korea: Multicenter Study

권희,이숙향,김성은,이재현,지영구,강혜련,박병주,박중원,홍천수 대한의학회 2012 Journal of Korean medical science Vol.27 No.3

Hepatic adverse drug reactions (ADRs) to certain drugs may differ within each country, reflecting different patterns of prescription, socioeconomic status, and culture. The purpose of this study was to assess the suspected cause of hepatic ADRs using the spontaneously reported pharmacovigilance data from Korea. A total of 9,360 spontaneously reported adverse drug events (ADEs) from nine Pharmacovigilance Centers were analyzed. Risk of hepatic ADEs was assessed by calculating the reporting odds ratio (ROR). Of the 9,360 cases, 567 hepatic ADEs were reported. The most frequently prescribed drug classes inducing hepatic ADEs were anti-tuberculotics, cephalosporins, valproic acids, penicillins, quinolones, non-steroidal anti-inflammatory drugs (NSAIDs), anti-viral agents, and statins. ROR values were especially high in anti-tuberculosis drugs, systemic antifungal drugs for systemic use, anti-epileptics, propylthiouracil, and herbal medicines. Underlying diseases such as tuberculosis (6.9% vs 0.9%), pneumonia (4.9% vs 1.7%), intracranial injury including skull fracture (4.5% vs 0.9%), HIV (3.4% vs 0.4%), subarachnoid hemorrhage (2.8% vs 0.5%), and osteoporosis (2.4% vs 1.4%) were significantly more common in hepatic ADE group. In conclusion, anti-infective drugs, anti-epileptics, NSAIDs and statins are the most common suspects of the spontaneously reported hepatic ADEs, in Korea. Careful monitoring for such reactions is needed for the prescription of these drugs.

위전절제술 후 Early Enteral Nutrition과 Total Parenteral Nutriton의 전향적 비교 연구

권희,손은선,고종희,안지현,송승은,이은주,이호선,조미화,강정애,신혜선,윤석준,윤호영,김충배 한국병원약사회 2007 병원약사회지 Vol.24 No.4

This study was aim to compare nutritional parameter, immune competency, and types of complication between early enteral nutrition (EN) and total parenteral nutrition (TPN) after total gastrectomy. Patients were prospectively randomized to receive early EN by nasoenteral tube (n=17) or TPN via central venous catheter (n=16) after total gastrectomy in Yonsei University Health System from March 2006 to July 2007. The nutritional goals were 25kcal/kg/day for total daily calories and 1.5g/kg/day for total daily protein. No significant differences were found between the two groups regarding nutritional parameters and length of stay. However, AST/ALT level on post operating day (POD) 7 was slightly higher in the TPN group compared to the early EN group. There were no infectious complications in either group. Complications encountered in the early EN group were GI complications such as nausea, vomiting, abdominal distension and increased AST/ALT levels whereas in the TPN group, total bilirubin and ASL/ALT elevations. Considering the fact that both groups showed small decrease in weight, active nutritional support is essential in patients with total gastrectomy. There were no statistically significant differences between early EN and TPN group following total gastrectomy in terms of nutritional parameters and immune competency. Based on this result, both early EN and TPN seem to be appropriate in supplying nutrition after total gastrectomy.

승용디젤엔진용 러버코팅 크랭크 샤프트 스프라켓 개발

권희도(Heedo Kwon),송계웅(Kyeoong Song),이병철(Byungchul Lee),이종원(Jongwon Lee),김형신(Hyungshin Kim) 한국자동차공학회 2014 한국자동차공학회 학술대회 및 전시회 Vol.2014 No.11

The purpose of this paper is chain whine noise improvement on the diesel engine with rubber coated sprocket. Chain whine noise is one of the biggest issues on the engine using the chain as timing drive system. Furthermore, the rubber coated sprocket can meet durability target and can develop better noise behavior by optimizing the nipple shape of rubber coated sprocket. The optimized nipple shape can help the progressive contact when the chain was engaged in the sprocket.

인테리어 스타일리스트 박래경 씨의 감각적인 집

권희란,Gwon, Hui-Ran 한국주택협회 2007 주택과 사람들 Vol.201 No.-

집을 꾸미는 데 둘째가라면 스타일리스트 박래경 씨의 분당 전원 주택은, 소탈하면서도 내추럴한 느낌이 강한 곳이다. 화려하게 꾸미지 않아도 멋스러움이 묻어나는 그녀의 집은 화이트와 브라운의 두 가지 컬러를 적절하게 배합해 꾸며진 심플하면서도 세련된 공간이다.

단순미로 창조한 편안함이 있는 곳-'카페 윈'

권희란,Gwon, Hui-Ran 대한제과협회 1997 베이커리 Vol.4 No.-

오데사 국립 음대 신문희 교수의 삶과 공간

권희란,Gwon, Hui-Ran 한국주택협회 2006 주택과 사람들 Vol.193 No.-

러시아에서 동양인 최초의 젊은 여교수로 유명세를 치른 작은 체구의 신문희 교수. 영국의 왕립음악학교, 이탈리아에서 정식 성악 코스를 거친 그녀는, 이제 보수적이면서도 정적인 한국의 클래식 음악계를 활기찬 손길로 노크하고 있다. 그것도 정통 클래식이 아닌 크로스오버 음악으로. 음악인이기 전에 한없이 꿈 많고 여린 감성의 소유자인 그녀가 말하는 '나의 인생과 나의 집'.