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      • KCI등재

        Umbilical trocar port site keloid management using a transposition flap after laparoscopic surgery

        권효정,김정휴,Chae Rim Lee,최장연,문석호,전영준,오득영 대한미용성형외과학회 2021 Archives of Aesthetic Plastic Surgery Vol.27 No.4

        Background Keloids can occur anywhere in the human body. They are difficult to remove and can cause distress in patients. Although many options are available to treat keloids, no single method is considered the optimal treatment of choice. The authors encountered cases where an umbilical keloid developed at the trocar site after laparoscopic surgery and managed the keloid using a transposition flap. Methods A total of 10 umbilical keloid patients treated from 2013 to 2020 were included in this study. All patients developed a keloid due to the placement of a laparoscopic trocar incision port, and their major complaints varied from an asymptomatic nodule to pruritus or pain. All excisions were performed under local anesthesia, and transposition flaps were planned afterward. The surrounding tissue was rearranged so that the shape of the umbilicus was deformed to the minimum extent possible. The keloid scars were examined both preoperatively and 6 months postoperatively using the Patient and Observer Scar Assessment Scale (POSAS). Results All surgical wounds healed well without complications. The average time interval from laparoscopic surgery to keloid scar revision was 4.3 years. The mean postoperative follow-up period was 10.9 months, and no patient underwent reoperation. Four patients were treated with triamcinolone after surgery due to mild hypertrophy or pruritus. The POSAS observer scale showed significantly decreasing scores over time in all patients (P=0.002). Conclusions Cosmetically unfavorable keloids that form in the umbilicus following laparoscopic surgery can be improved with a simple procedure using excision and transposition flaps.

      • KCI등재

        Vitamin D3 up-regulated protein 1 controls the priming phase of liver regeneration

        권효정,홍성국,남기환,최인표,김대용,김형진,원영석 대한수의학회 2013 Journal of Veterinary Science Vol.14 No.3

        Vitamin D3 up-regulated protein 1 (VDUP1) is a potent growth suppressor that inhibits tumor cell proliferation and cell cycle progression when overexpressed. In a previous study, we showed that VDUP1 knockout (KO) mice exhibited accelerated liver regeneration because such animals could effectively control the expression of cell cycle regulators that drive the G1-to-S phase progression. In the present study, we further investigated the role played by VDUP1 in initial priming of liver regeneration. To accomplish this, VDUP1 KO and wild-type (WT) mice were subjected to 70% partial hepatectomy (PH) and sacrificed at different times after surgery. The hepatic levels of TNF-α and IL-6 increased after PH, but there were no significant differences between VDUP1 KO and WT mice. Nuclear factor-κB (NF-κB), c-Jun-N-terminal kinase (JNK),and signal transducer and activator of transcription 3 (STAT-3)were activated much earlier and to a greater extent in VDUP1KO mice after PH. A single injection of TNF-α or IL-6 caused rapid activation of JNK and STAT-3 expression in both mice,but the responses were stronger and more sustained in VDUP1KO mice. In conclusion, our findings provide evidence that VDUP1 plays a role in initiation of liver regeneration.

      • 飮食物쓰레기의 效率的 管理를 위한 物理的 特性 및 處理

        권효정,정영헌,김임경,심언봉,오광중 부산대학교 환경문제연구소 2003 環境硏究報 Vol.21 No.-

        This study was conducted to manage food wastes in Korea efficiently. We carried out an experiments on food wastes generated from Yeonjae gu, Pusan as a representative boundary according to the measurement of apparent density, generation quantity, physical characteristics, proximate analysis, and elemental analysis as well as drying and carbonizing, and also tested the hazardous materials in fertilizer and compost from public and private recycling center in operation. The purposes of this study are to investigate current status of food wastes recycling methods and facilities, to examine the fuelization of food wastes, and to suggest the cost effective food wastes treatment plans. Based on the results of the analysis of apparent density and water content in food wastes, it was revealed that the apparent density of food wastes was in inverse proportion to the water content. The water content of food wastes was highly influenced by the fruit and vegetables such as watermelons. These results indicate that the food wastes with about 75 ~80wt% initial moisture content should be reduced under 70wt% moisture content by drying process pier to throwing away. Comparing the heating values of the food wastes which were calculated by Dulong's equation and Steuer's equation it was revealed that Steuer's equation(HHV 5,186 kcal/kg, LHV 880 kcal/kg) was more compatible than Dulong's equation(HHV 4,676 kcal/kg, LHV 330 kcal/kg) because the results of proximate analysis for the food wastes were very similar to those of sewage sludges. Additionally, to reduce water contents of food wastes under 60wt% as acceptable water contents for fuelization, it was also found that blending with 25wt% chars made from food wastes was more efficient than the drying of food wastes itself at 105°C, 45minutes in view of completion time. Furthermore, these chars generated from food wastes (about LHV 6,608 kcal/kg) comparable to commercial charcoal(LHV 7,134 kcal/kg) generated from oak trees and lower ash contents(under 15wt% of chars) than those.

      • KCI등재

        A Review on the Clinical Use of the Eight Extra Meridians

        권효정,박동석,남상수,김용석 대한침구의학회 2009 대한침구의학회지 Vol.26 No.3

        목적 : 기경팔맥의 임상활용을 위하여 기경팔맥의 개요와 기경팔맥을 이용한 침 치료법의 장점과 기존의 침 치료와의 차이점을 알아보고자 하였다. 방법 : 기경팔맥의 기원과 학문적 이론의 체계를 알아보기 위하여 한국학술정보(주)를 통해 검색한 국내 논문 9편을 참고하고, 기경팔맥을 이용한 치료법에 관한 국내외 서적 2편을 수집하였다. 또한 MedLine에서 기경팔맥을 이용한 치험례와 임상연구에 대해 영어로 작성된 논문 2편을 소개하였다. 결론 : 기경팔맥을 이용하면 정경 치료와 달리, 통증 등의 실체가 있는 질환에 대해 즉각적인 효과를 보이는 치료를 소수의 혈자리 자침으로써 간편하게 행할 수 있다. 또한 병증과 경락 유주 사이의 공간적 불일치가 있거나, 복잡한 정황으로 인해 四診을 통한 변증이 어려운 경우에 팔맥교회혈 또는 영구팔법 등의 기경팔맥을 이용한 치료를 사용할 수 있다.

      • KCI등재

        편기세정제가 오수처리시설의 미생물 활성에 미치는 영향

        권효정,박수영,조광명,김홍선 ( Hyo Jung Kwon,Soo Young Park,Kwang Myeung Cho,Hong Sun Kim ) 한국물환경학회 1997 한국물환경학회지 Vol.13 No.1

        The effects of a drop-type toilet bowl cleaner(TBC) on the activity of microorganisms of sewage treatment facilities were tested by various experiments such as biochemical methane potential(BMP) measurement, oxygen uptake rate(OUR) measurement, a semicontinuous anaerobic digestion and an activated sludge treatment experiments. The results of the BMP test showed that the methane production rate gradually decreased as the TBC concentration increased, showing little gas production above 5,000㎎/L. In the anaerobic digestion experiment, the gas production and methane content decreased when the TBC concentration in the sludge fed increased to 6,667㎎/L. The OUR test failed to show a threshold TBC concentration which influences the activity of activated sludge. However, the CSTR activated sludge study showed that the activity of the activated sludge can be affected at TBC concentrations above 5,000㎎/L.

      • KCI등재

        20대의 선거 참여를 장려하기 위한 모바일 서비스 디자인 연구

        권효정 사단법인 인문사회과학기술융합학회 2017 예술인문사회융합멀티미디어논문지 Vol.7 No.5

        In case of the people in their 20s who experienced elections for the first time, or had an experience in giving up on voting due to indifference to elections, their turnout at elections is still insufficient in comparison with other generations, and their interest in elections is also relatively low. The preceding researches with regard to this issue have been restricted to the quantitative analysis of factors in voter turnout from the policy aspects, and to the plan for promotion of universal voters’ participation in elections using media. Accordingly, this study researched and analyzed the relevant cases first, and conducted online-based user research targeting those in their 20s without election experience. It intended to make those in their 20s have interest in elections and perceive the importance of elections. The study also searched for the ways to increase the voter turnout at elections by suggesting the mobile election information service using a special user experiential analysis tool based on the above research. This study may have its originality and value as extensible convergence research in terms that it attempted open research from the perspective of design which could arouse interest of those in their 20s while overcoming the limitations of the existing preceding researches. 선거 경험이 최초이거나 혹은 무관심하여 투표를 포기한 경험이 있는 20대의 경우, 여전히 타 세대에 비해 선거참여율이 미비한 실정이고, 선거에 대한 관심도 상대적으로 낮다. 기존의 관련된 연구는 정책적 측면에서 투표 참여 요인에 관한 정량적 분석 연구이거나, 미디어를 활용한 보편적인 유권자의 선거참여를 촉진하는 방안에 관한 연구에 국한되어왔다. 따라서 본 연구에서는 먼저, 관련된 유사 사례를 조사 분석하고, 선거경험이 없는 20대를 대상으로 하여 온라인 기반의 사용자 조사를 실시하였다. 이를 기반으로 특수한 사용자의 경험적 분석 도구를 적용한 모바일 선거 정보 서비스를 제안함으로서, 20대에게 선거에 관심과 중요성을 인식시키고, 선거참여율을 향상시킬 수 있는 방안을 모색해보고자 하였다. 기존 선행연구의 한계를 극복하고, 20대의 흥미를 유발할 수 있는 디자인적 관점에서 열린 연구를 시도했다는 측면에서 독창성을 가진다고 볼 수 있으며, 또한 확장성 있는 융합연구로서의 가치를 가진다고 할 수 있다.

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