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권유진,손다혜,정태하,이용재 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.1
Since ancient times, licorice, the root of Glycyrrhiza glabra, has been known to have a wide spectrum of therapeutic effects. Glycyrrhizin is cleaved to glycyrrhizic acid, which is subsequently converted to glycyrrhetic acid by human intestinal microflora. Glycyrrhetic acid is a potent inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD) and performs a range of corticosteroid-like activities. The pharmacologic effects of licorice contribute to its anti-inflammatory, antioxidative, anti-allergenic, and antimicrobial properties. Licorice has been used to treat liver disease, gastrointestinal disorders, oral disease, and various skin disorders and has been used in gum, candy, herbs, alcoholic beverages, and food supplements. Licorice and its extracts, especially glycyrrhizin, can be taken orally, through the skin (in the form of gels and oils), and intravenously. Licorice demonstrates mineralocorticoid-like activity not only by inhibiting 11β-HSD2, but also by binding to a mineralocorticoid receptor, leading to potentially adverse risks of mineralocorticoid-like overactivity. Chronic use of licorice can lead to hypokalemia and hypertension, and some people are more sensitive to licorice exposure. Based on clinical trials, this review summarizes the positive effects of licorice and other reported side effects.
뚜껑문 안와저 골절에 있어서 망상 흡수성 판을 이용한 관혈적 정복술 및 내고정술
권유진,김지훈,황재하,김광석,이삼용,Kwon, Yu-Jin,Kim, Ji-Hoon,Hwang, Jae-Ha,Kim, Kwang-Seog,Lee, Sam-Yong 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.5
Purpose: Trapdoor orbital blowout fracture is most common in orbital blowout fracture. Various materials have been used to reconstruct orbital floor blowout fracture. Absorbable alloplastic implants are needed because of disadvantages of nonabsorbable alloplastic materials and donor morbidity of autogenous tissue. The aim of the study is to evaluate usefulness of absorbable mesh plate as a reconstructive material for orbital blowout fractures. Methods: From December 2008 to October 2009, 18 trapdoor orbital floor blowout fracture patients were treated using elevator fixation, depressor fixation, or elevatordepressor fixation techniques with absorbable mesh plates and screw, depending on degree of orbital floor reduction, because absorbable mesh plates are less rigid than titanium plates and other artificial substitutes. Results: Among 18 patients, 5 elevator fixation, 4 depressor fixation, and 9 elevator and depressor fixation technique were performed. In all patients, postoperative computed tomographic (CT) scan showed complete reduction of orbital contents and orbital floor, and no displacement of bony fragment and mesh plate. Mean follow-up was 10 months. There were no significant intraoperative or postoperative complications. Conclusion: Three different techniques depending on the degree of orbital floor reduction are useful for open reduction and internal fixation of trapdoor orbital floor blowout fracture with absorbable mesh plates.
가정과 교사교육에서 금융소비자교육(Personal Financial Education) 반영 가능성 연구
권유진,이진화 중앙대학교 한국교육문제연구소 2011 한국교육문제연구 Vol.29 No.2
본 연구는 문헌분석과 가정과 교육과정 문서 및 가정교육과 소재 대학의 교육과정 분석을 통해 가정과 교사교육에 있어서 금융소비자교육의 중요성을 인식하고 다양한 금융소비자교육 내용 구성 틀을 기초로 하여 가정과 교사교육에 적용 가능성 및 발전 방향을 제시하는 데 그 목적이 있다. 연구방법은 주로 문헌 분석 및 실태 분석을 실시하였으며, 그 대상은 가정과 교육과정 문서 및 전국 가정교육과 소재 대학을 대상으로 하였다. 분석결과 교사교육을 위한 교육과정에는 가계경제와 소비자교육 중심 과목들이 주로 개설되어 있으며 중등 임용 평가 영역에 따른 과목명이 고르게 나타나지 않았다. 향후 금융소비자교육의 일관된 명칭과 개념을 가정교과에 적합하도록 논의할 필요가 있으며, 또한 소비자교육 외에 소비자관련법, 소비자로서의 권리와 책임, 소비자 문제해결과 관련된 과목이 다양하게 개설되어야 하며, 생애주기에 따른 진로설계와 맞물려 재무 설계 관련 내용이 교육과정에 포함되어야 하는 등 가정교과와 관련된 맥락이 다양하게 개발되어야 한다. The importance of the financial and consumer education is recently emphasized and secondary education in home economics as a required subject involves the financial and consumer education. In addition, the financial and consumer education should be reflected in teacher education for home economics teachers who conduct teaching and learning activities related to the financial and consumer education in a class. The purpose of this study is to suggest the frame of reference for a content analysis on the financial and consumer education through a literature review and analyze it based on the basic completion subject assessment supported by Korean Institution for Curriculum and Evaluation(KICE) and developed by Korean Home Economics Education Association(KHEEA). And its second purpose is to create potential for reflecting the financial and consumer education in teacher education for primary and secondary teachers in home economics, analyzing names of subjects related to the financial and consumer education in the college of education home economics and to search the development of the financial and consumer education.
권유진,박혜원,김민주,이병섭,Ellen Ai-Rhan Kim 대한의학회 2015 Journal of Korean medical science Vol.30 No.4
This study aimed to evaluate the validity of the ages and stages questionnaire in Korean(ASQ 1st edition, Korean Questionnaires, Seoul Community Rehabilitation Center, 2000)for premature infants. The study population consisted of 90 premature infants bornbetween January 1, 2005, and December 31, 2011, who were tested using the ASQ(Korean) and Bayley Scales of Infant Development (BSID) (II) at a corrected age of 18-24months. The validity of the ASQ (Korean) using cut-off values set at < -2 SD was examinedby comparing it to the BSID (II) components, namely, the mental developmental index(MDI) or psychomotor developmental index (PDI), which were both set at < 85. Thecalculation of the sensitivities, specificities, positive predictive values, and negativepredictive values of the ASQ (Korean) components revealed that they detected infants withneurodevelopmental delay with low sensitivity and positive predictive values, however, thecommunication domain showed moderate correlations with MDI. The failure in more thanone domain of the ASQ (Korean) was significantly correlated with the failure in MDI. TheASQ (Korean) showed low validity for screening neurodevelopmentally delayed prematureinfants.
McCune-Albright 증후군의 임상적 및 내분비학적 특징
권유진,김유미,김자혜,최진호,유한욱,Kwun, Yoojin,Kim, Yoo-Mi,Kim, Ja-Hye,Choi, Jin-Ho,Yoo, Han-Wook 대한유전성대사질환학회 2013 대한유전성대사질환학회지 Vol.13 No.2
Purpose: McCune-Albright syndrome (MAS) is caused by activating mutations in the GNAS gene, resulting in peripheral precocious puberty, caf$\acute{e}$-au-lait spots, and polyostotic fibrous dysplasia (POFD). The aim of the present study was to describe the diverse clinical and endocrine characteristics of patients with MAS. Methods: Seven patients with MAS were included in this study and medical charts were reviewed retrospectively for following parameters: patient's sex and age at diagnosis, POFD, ovarian cysts, and precocious puberty. Results: The mean age at diagnosis was $5.8{\pm}4.2$ years. One patient was male (14%) and the other six patients were female (86%). Peripheral precocious puberty was associated with 6 patients (86%). Five patients manifested premature menarche as early as 2 to 5 years of age. Letrozole was administered to 4 patients, tamoxifen to one patient and GnRH agonist to one patient. Five females developed ovarian cysts. Thyroid function tests were performed in all patients and one patient showed hyperthyroidism (14%) and has been treated with methimazole. One patient presented with pseudohypoparathyroisdism, phosphaturia, calciuria suggesting hypophosphatemic rickets. Six patients (86%) revealed POFD. One patient had symptoms of optic nerve compression and secondary esotropia and 2 patients had bone pain. Conclusion: This study described clinical characteristics and endocrine complications of patients with MAS. Careful physical examinations with history taking and serial endocrine function tests should be needed to detect complications such as endocrinologic hyperfunction and POFD.