Vitamin B_12缺乏이 血液成分 및 細胞內 Mitochondria enzyme Activity 에 미치는 영향

權容駿 대구효성가톨릭대학교 1982 연구논문집 Vol.24 No.3

Vitamin B_12 deficiency has been shown to result in an decrease of the bodyweight, and an increase of the succinate dehydrogenase CoQ reductase activityof liver mitochondria of rat. But There was no effect on the succinate dehydrogenase CoQ reductase activityof heart Mitochondria of rat. CoQ_10 had no positive effect on the hematological data, body weight, andSuccinate dehydrogenase CoQ reductase activity of both liver and heart of rat.

노인요양시설의 마케팅 포지셔닝 분석에 관한 연구 - 안양시 5개 시설을 중심으로 -

권용준,이태휘,한종길 한국노인복지학회 2012 노인복지연구 Vol.0 No.55

The goal of private Elderly Care Facilities, not public, is to make profit, and in order to make profit, Marketing strategies for dominating the advantageous market in advance are very fundamental and significant area. But the research on this area is insufficient. There were varied researches on marketing strategy at various fields ever, most studies made in the field of elderly care facilities are related to service quality improvement or elderly care facilities. So at this study, selected attribute will be drawn through advanced research of selected attributes, on the basis of this advanced research, marketing positioning will be conducted on elderly care facilities for urban area. 노인요양보험제도가 시행된지 3년이 지났지만, 노인요양시설과 관련한 연구는 서비스 품질 향상이나 정책개선을 다룬 연구에만 치우쳐 있는 실정이다. 이러한 측면에서 본 연구에서는 노인요양시설의 선택속성을 바탕으로 한 노인요양시설 마케팅 포지셔닝 분석을 실시하였다. 분석대상은 안양시 5개 시설에 어르신을 위탁한 부양의무자를 대상으로 하였으며 노인요양시설의 선택속성에 대한 고객만족도를 조사하여 이를 포지셔닝하였다. 분석 결과, A시설은 가족 및 지역사회연계서비스, D시설은 구전효과, E시설은 시설의 규모면에서 각각 고객만족도가 높았고 B시설과 C시설은 교통의 편리함에서 중첩된 만족도를 보여 주간보호 노인에 대한 교통서비스 확대가 향후 경쟁우위를 점할 수 있는 요인으로 분석되었다.

회화 공간과 텍스트 : 샤갈(Chagall)과 아폴리네르(Apollinaire)의 공간구조

권용준 한국프랑스학회 2004 한국프랑스학논집 Vol.47 No.-

단백질 측정용 SH-SAW 센서 개발

권용준,김재호,고광락,노용래 한국음향학회 2004 韓國音響學會誌 Vol.23 No.1

본 연구에서는 항원-항체 결합반응을 통해 액상의 단백질 분자를 감지할 수 있는 SH형 SAW센서를 개발하였다. 측정하고자 하는 항원으로는 anti-Human-immune-globulin (anti-HigG) 단백질을, 이에 대응하는 항체로는 HigG를 채택하였다. 압전 단결정 LiTaO₃를 사용하여 100 MHz로 발진되는 센서를 제작하고, 센서의 지연선 위에 Ti/Au층을 증착하였다. 증착된 Au층 위에 SAM (self assembled monolayer)을 형성시켜서 추가되는 항원의 농도에 의한 센서의 주파수 변화를 측정하였다. 개발된 센서의 최소검출단위는 노이즈 레벨 400 Hz 이하 값에 10.8 ng/ml/Hz의 민감도를 가지며, anti-HigG 항원의 질량하중 효과에 대해 안정적인 반응을 보였다. We developed SH-SAW sensors to detect protein molecules in liquid solutions applying a particular antibody thin film on the delay line of transverse SAW devices. The antibody investigated was human-immune-globulin G (HigG) to hold the antigens (anti-HigG) in the protein solution. We fabricated the sensor generating 100 MHz with the piezoelectric single crystal LiTaO₃. We measured the frequency change of the sensor by adding the anti-body concentration on SAM (self assembled monolayer) deposited on the Au layer. The sensor showed stable response to the mass loading effects of the anti-HigG molecules with the sensitivity up to 10.8 ng/ml/Hz at noise level 400 Hz below.

Thermodynamic Investigation of the Formation of Complexes between Norfloxacin and Various Mononucleotides

권용준,한성욱,이현미,조태섭,이동진 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.9

The fluorescence of norfloxacin was quenched by various nucleotides. The ratio of the fluorescence intensities in the absence and presence of nucleotide was linearly dependent on nucleotide concentration, suggesting that quenching occurred through the formation of nonfluorescent norfloxacin-nucleotide complexes. The gradient of the linear relationship represented the equilibrium constant of complex formation; it decreased with increasing temperature. The slopes of van’t Hoff plots constructed from the temperature-dependent equilibrium constants were positive in all cases, indicating that complex formation was energetically favorable – i.e.,exothermic, with negative Gibb’s free energy. The equilibrium constant increased when triphosphate was used instead of monophosphate. It also increased when the oxygen at the C'_2 position of the nucleotide was removed. Both enhancements were due to entropic effects: entropy decreased when complexes with AMP or GMP formed, while it increased when norfloxacin complexed with ATP, GTP, dAMP and dGMP.

별리 외 1편

권용준 천년의시작 2008 (계간)시작 Vol.7 No.3

점토계소지내에서 전기로 더스트 중금속의 소성 온도별 안정화거동

권용준,김유택,이기강,김영진,강승구,김정환,Kwon, Yong-Joon,Kim, Yoo-Taek,Lee, Gi-Gang,Kim, Young-Jin,Kang, Seung-Gu,Kim, Jung-Hwan 한국세라믹학회 2002 한국세라믹학회지 Vol.39 No.8

전기로 더스트를 점토 또는 백토와 혼합하여 소성온도에 따른 전기로 더스트 내에 존재하는 Cr, Cd, Cu, Pb, Fe, Zn 중금속들의 거동을 조사하였다. 전기로 더스트를 점토와 백토에 각각 0∼50 wt%씩 첨가하였고, 소성은 $200^{\circ}C$ 간격으로 $200∼1200^{\circ}C$ 범위 내에서 수행하였다. 소성된 시편은 TCLP법에 의한 용출실험을 거친 후 ICP-AES로 분석하였다. 중금속표준용액을 이용한 양이온 교환능 실험결과 점토와 백토가 기존의 중금속 흡착제인 제올라이트와 비슷한 중금속 양이온 교환능을 보였으며, Cr에 대해서는 더 우수한 교환능이 관찰되었다. TCLP법에 의한 용출실험 결과 Cr과 Fe는 모든 시편에서 거의 용출되지 않았으며, Cd과 Zn은 소성온도가 증가하고 전기로 더스트의 함량이 적을수록 용출량이 감소하였다. 점토 또는 백토와 전기로 더스트를 혼합 소성 시 일차적으로 양이온 교환능에 의해 중금속이 준안정화되고 이차적으로 공융반응에 의하여 중금속들이 완전하게 고정화되어 중금속 용출을 억제하는 것으로 추정된다. 본 연구에서 백토가 점토 보다는 전기로 더스트 중금속의 안정화에 더 효과적이었다. Stabilization behavior of Cr, Cd, Cu, Pb, Fe and Zn heavy metals in the EAF dust was investigated by adding EAF dust to clay or white clay, respectively, up to 50 wt% with 10 wt% intervals and sintering at temperatures between 200 and $1200^{\circ}C$ with $200^{\circ}C$ intervals with an aid of ICP-AES followed by TCLP test to evaluate heavy metal cation exchange capacity of the clay or the white clay. The clay or the white clay had a better Cr ion exchange capacity than that of zeolite. The TCLP leaching test for the sintered specimens showed that Cr and Fe were rarely detected for all the specimens and the concentration of Cd and Zn decreased with increasing sintering temperature and decreasing EAF dust contents respectively. When the clay or the white clay were mixed with EAF dust, cation exchange may occur between the clay and the EAF dust so that the first stabilization of the mixtures containing semistabilized heavy metals may happen. Stabilization of heavy metals in the ceramic bodies was further completed probably due to the eutectic reaction caused by the sintering of semi-stabilized mixtures. It was conceivable that the white clay rather than the clay may be a better stabilizer for the EAF dust containing heavy metals.

Ethionine투여로 인한 Rat의 肝과 腎臟의 脂質過酸化와 脂質量의 變化에 미치는 BHT의 영향

권용준 대구효성가톨릭대학교 1991 연구논문집 Vol.43 No.1

The present study was undertaken to evalute the effect of ethionine and butylated hydroxytoluene(BHT) on the changes of lipid peroxidation, total lipid, phospholipid, total cholesterol, and total triglyceride of liver and kidney in male rat. The results obtained were summarized as follows; 1) Hepatic and renal lipid peroxidation were significantly increased by ethionine administration(I.P.). But after concomitant administration of ethionine (I.P) and BHT(I.P or P.O.), lipid peroxidation of liver and kidney were significantly decreased in comparion to that of ethionine alone injection(I.P) 2) Total lipid and triglyceride of liver were significantly increased by ethionine injection (I.P.). But after concomitant administration of ethionine(I.P.) and BHT(I.P. or P.O.), these values were significantly decreased in comparison to that of ethionine alone injection(I.P.) 3) Althought total lipid and triglyceride of kidney by ethionine alone injection(I.P.) were slighylt increased in comparison to that of normal group, there were no differenc betrween these two groups. After concomitant administration of ehionine(I.P.) and BHT(I.P. or P.O), these values were significantly decreased in comparison to that of ethionine alone injection(I.P.). 4) There were no effect on phospholipid and total cholesterol of liver and kidney by ethionine alone injection(I.P) or concomitant administration of ethionine(I.P.) and BHT(I.P. or P.O.)

한스 홀바인의 <외국 대사들>에 나타난 시적 구조 : 죽음의 이미지를 중심으로

권용준 한국프랑스학회 2003 한국프랑스학논집 Vol.41 No.-

뒤샹 비용과 입체주의 조각 : 아폴리네르의 조형적 시각을 중심으로

권용준 한국프랑스학회 2012 한국프랑스학논집 Vol.77 No.-

Aux yeux d'Apollinaire, Duchamp-Villon était un vrai et authentique sculpteur cubiste avec Bransusi et Archipencko comme il le précise dans son ouvrage Méditations esthétiques Les Peintres cubistes, où est montrée son idée d'une sculpture absolue. On pourra vérifier son nouvelle esthétique sculpturale, dite cubiste, dans ses quelques oeuvres. On peut remarquer l'élimination des détails faciaux et l'éxagération de la délinéation caractéristique du crâ̂ne dans le Baudelaire. Cette simplicité extrê̂me par les lignes de force projette l'image de ce poète moins comme d'un humain que comme d'une intelligence désincarnée. Le sculpteur recrée la face saturnienne et introspective du poète, révélée par la forte sphère du crâ̂ne, et présente le résultat d'un processus non seulement sculptural mais aussi intellectuel. Il trouve la clef d'une libération des méthodes et des motifs périmés, s'approche du langage architectural et de la qualité directe du plans de l'ordre géométrique, caractère essentiel du cubisme avec la simplicité. Le point essentiel de cet esthétique n'échappa pas aux yeux d'Apollinaire qui prend sérieux sa capacité de conception, pour une autre réalité, et, pour cette raison, le poète fait attention au Baudelaire. Les Amants de Duchamp-Villon sont un chef-d'oeuvre parmi série des reliefs de 1913. Cette oeuvre représente la figure inversée d'un homme et d'une famme, avec des éléments uniques, caractérisés par des lignes de force et des accents formels. On apprécie là le principe radical du cubisme : structure par incision condensée et accumulation adaptée de parties fragmentaires, accentuées par une anatomie géométrique. Cette composition est déterminée par le mouvement interne, sumultané, issu de l'harmonie entre le creux et la saillie. D'autre part, la composition abstraite est remarquable sans perdre une taille tri-dimentionnelle. Dans ce temps-là, Apollinaire met l'accent souvent sur le simultanéisme. Pour cette raison il apprécie ‘la recherche d'atmosphère’ dans les Amants. Pour expliquer l'univers nouveau de Duchamp-Villon qui n'a plus rien à faire avec l'imitation, Apollinaire introduit le sens de l'architecture. Il définit son effort pour se dégager de la nature comme l'achèvement d'une architecture, dont le sens n'est autre que la sculpture fidèle à son propre esthétique et indépendante des autres caractères hors des attributs sculpturaux. Il s'agit de la sculpture conceptuelle qui garde son caractère absolu. Nous pouvons facilement accepter qu'Apollinaire annonce, pour achever une pureté sculpturale, la transfiguration du réel évoqué par le mystère du visible. C'est une aventure vers une nouvelle histoire de la sculpture abstraite, due à la conception dynamique de la nature. Apollinaire veut voir naî̂tre une sculpture différente, inattendue, dans la ligne directe du grand principe établi par les jeunes artistes cubistes et admis par le sculpteur audacieux fixant les yeux sur l'avenir, Duchamp-Villon ; l'avenir de la sculpture qui s'épanouira dans son esthétique de l'esprit nouveau. Ce sera un nouveau surréalisme.