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      • 간세포암에서 CD34 발현의 임상적 의의에 관한 연구

        권기범,최병주,편준철,윤병철,이상욱,한병훈 고신대학교 의학부 2001 高神大學校 醫學部 論文集 Vol.16 No.1

        Background Angiogenesis seem to be essential for hepatocellular carcinoma progression It could be evaluated by observing the CD34 expression. In the present study, we studied to define whether or not angiogenesis has the correlation with clinicopathological characteristics of hepatocellar carcinoma. Methods In 46 cases of hepatocellar carcinoma, we examined the CD34 expression in tumor and surrounding non-tumorous liver tissue using immune histochemistry Microvessel density was also calculated Results The expression of CD34 was diffuse and strong in all hepatocellular carcinoma tissue and sparse in adjacent area of the surrounding cirrhotic regenerating nodule The mean microvessel density was not significantly different between in the group of Edomondson's grade Ⅰ-Ⅱ(n=30, 25 9±15 5 ) and the group of Edmondson's grade Ⅲ-Ⅳ(n=16; 33.1±11.8; P=0.085) And it was not significantly different either between the patients (n=27) with tumor smaller than 4.6cm (30.6±15.1) and the patients (n=19) with larger than 4.6cm (25.3±13.6, P=0.225) in diameter. However overall survival was worse in patients (n=22) with high microvessel density (>284) than in patients (n=24) with low microvessel density significantly (P=0.043) Conclusion The expression of CD34 may serve as the diagnostic tool in differentiating hepatocellular carcinoma from benign regenerating nodule. Although microvessel density showed no significant correlation with size and histopathological grade of hepatocellular carcinoma, angiogenesis may be used as a prognostic marker.

      • 최근 7년간 충남 북서지역의 소아에서 발생한 쯔쯔가무시열의 임상적 고찰

        권기범,박준수 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.2

        Purpose : Tsutsugamushi fever has been reported in Korean children. However there are not any reports regarding children of the Northwestern Choongnam province. Hence we are reporting clinical features of the Tsutsugamushi disease in chidren of these area. Methods : We reviewed clinically or serologically confirmed 11 Children of Tsutsugamushi fever from Cheonan and Choongchung Nam Province, who were admitted to Soonchunhyang University Cheonan Hospital from October 1997 through October 2003. We investigated the age, sex ratio, clinical manifestations, laboratory findings and response to therapy. Results : The mean age of patients was 6.5 years, ranging from 2 to 14 years. 7 cases(63.6%) were bovs and 4 cases(36.4%) were girls. The mean duration of the treatment was 6.8 days. The most common symptoms were fever in all cases and cough in 2 cases (18.1%). Frequent signs were skin rash in all cases, eschar in 9 cases (81.8), regional lymphadenopathy in 3 cases (27.2%). The main locations of the eschars were neck in 3 cases(33.3%), and chest, thigh, penis, occipital, back, ear in each 1. Laboratory findings included leukopenia in 4 cases(36.3%), lejkocytosis in 3 cases(27.2%), anemia in 2, ESR elevation in 5, and positive CRP in all cases, SGOT elevation in 9 cases, SGPT elevation in 8 cases, positive passive hem agglutination test in 7 cases (63.6%). Clinical improvement was noticed in all cases after treatment with chloramphenicol, tetracycline, doxycycline, or roxythromycin. The mean duration for defervescence after treatment was 1.4 days. There were not complications or recurrence in any case. Conclusions : Tsutsugamushi fever have appeared in children of Cheonan and Choongnam Province. We should be aware of clinical manifestation such as fever, skin rash, eschar, and lymphadenopathy during the period of October and November in order to diagnose the Tsutsugamushi fever properly.

      • 合倂反對株主의 株式買受請求權

        權奇範 서울市立大學校 1988 論文集 Vol.22 No.-

        The remedy for a dissenting shareholder in a merger prescribed in §191 of the Korean Securities Exchange Act (hereinafter referred to as "The Act"), so-called "appraisal fright", is admittedly for the protection of minority shareholders. Affirming the plausibility of this right, this article examimes the relevant problems of §191 of The Act such as the procedure and requirements for perfecting this right and the basis for the valuation of dissenting shares. Especially, this artical criticizes the complexity of the valuation procedure and the lack of acceptable valuation basris, and suggests: i) this right be available in those unlisted corporations ; ii) this valuation procedure be shortened into two staged-private negotiation and judicial decision ; iii) all valuation factors be taken into consideration in the valuation procedure.

      • KCI등재

        Evaluation of Drilling Efficiency by Percussion Testing of a Drill Bit with New Button Arrangement

        권기범,조정우,송창헌,박진영,오주영,이재욱 한국정밀공학회 2014 International Journal of Precision Engineering and Vol. No.

        Rock drilling machines are commonly used for surface drilling, soil nailing reinforcement, tunnel excavation, and undergroundmining. These machines use drill bits that directly impact into the rock and are operated by percussive force and torque. Drill-bitbuttons need to be designed to increase drilling efficiency; here, we present the results of a series of single blow tests on granitic rocksamples using a piston drop type percussion testing system that enable us to compare the drilling efficiency of a new buttonarrangement design with conventional arrangements. Drilled rock volumes were measured by laser scanner after testing, and drillingefficiencies were evaluated by calculating percussive energies and drilled volumes. The results indicate that the new buttonarrangement design can be used to improve the drilling efficiency.

      • KCI등재

        무액면주식에 대한 소고

        권기범 법무부 2013 선진상사법률연구 Vol.- No.63

        The 2011 revision of the Korean Commercial Code((hereinafter refferd to as ‘KCC’) has newly introduced no-par value share to enhance corporate financing ability. However, leaving too many questions in the hands of interpreters, it shows several defects. From the author's point of view, further complementary minor amendements are to be followed as soon as possible. Firstly, additional provisions should be established concerning the conversion procedure including conversion ratio between par-value and no-par value share. Secondly, present regulation as to the cancellation of shares, consolidation of shares and share splits is to be ameliorated : among others, provisions as for the consolidation of shares must be wholly reset. And then, necessary differentiation between par-value and no-par value share should be provided in the cancellation, consolidation and split procedures. Thirdly, as for no-par value share, it is argued that both nominal and actual reduction of capital be allowed under Articles 438-446 KCC. Fourthly, it is argued that a corporation with no-par value shares may issue new shares correspondent to its capital increase out of capital surplus. Fifthly, it is argued that share dividends under Article 462-2 KCC be also allowed to those corporations with no-par value shares. Finally, a clear criteria should be introduced as to the calculation and accounting entry of capital and capital surplus in cases of extra-ordinary issuance of shares accompanied by corporate mergers, divisions and etc. 2011년 개정상법은 그 동안 액면주식만을 고집하던 것에서 탈피하여 무액면주식을 도입하였다. 자금조달의 원활화를 위한 일대 변혁으로서 환영받을 일이다. 그러나 실제 운용에서 발생할 수 있는 제반 문제점들에 대한 미세 조정 규정이 충분하지 못하여, 주식 소각, 주식병합, 주식분할, 주식배당, 액면주식과 무액면주식의 상호 전환, 자본금 감소, 법정준비금의 자본금 전입 등에 관하여 까다로운 해석상의 문제들을 야기한다. 그렇다고해서 이들에 대하여 액면주식에 관하여 그동안 확립된 해석론(그 중심에는 발행주식의 액면총액을 자본금으로 규정하는 상법 제451조 제1항이 있다)을 그대로 적용하기도 곤란하다. 이 글에서는 무액면주식을 실제 운용하는 데 있어서 발생하는 제반 의문점들을 살펴보고, 해석에 의해 보완이 되는 부분은 해석으로 그렇지 못한 부분에 대해서는 개정안을 제시하기로 한다. 첫째, 액면주식과 무액면주식의 상호 전환에 대하여 보다 상세한 입법적인 정리를 하여야한다. 개정상법은 단지 정관이 규정하는 바에 따라 하면 되는 것으로 규정하고 있으나, 이것만으로는 부족하다. 쟁점들에 대해 보다 명시적인 규정을 두어야 할 것이다. 예컨대 전환 비율이 1 : 1이 아닌 형태도 가능한지가 대표적이다. 둘째, 종래부터 주식의 소각·병합·분할에 대해서는 액면주식에 관하여도 의문점들이 적지 않았는데, 이번 무액면주식의 도입으로 상황이 더욱 복잡하게 되었다. 이 글에서는 무액면주식의 소각·병합·분할에 관한 해석론상의 의문점들을 살펴본 후, 입법론으로 주식소각·병합·분할에 관한 일반 규정을 두면서 그 적용에 있어서 액면주식과 무액면주식을 차별화하는 방안을 제시하였다. 셋째, 무액면주식을 발행한 경우에 실질상의 자본금 감소가 가능한가에 대하여는 개정상법의 해석론으로 가능하다고 본다. 넷째, 무액면주식이 발행된 경우 법정준비금의 자본금 전입시 신주발행을 할 수 있는지 여부에 대해 개정상법은 침묵하고 있는데, 개정상법의 해석론으로 가능하다고 본다. 다만, 입법론으로는 발행기준 등 이에 관한 명문 규정을 두는 것이 바람직하다. 다섯째, 무액면주식이 발행된 경우에도 주식배당이 가능하다고 해석되나, 입법론으로는 상법 제462조의2의 규정의 문언을 보다 명확하게 개정할 필요가 있다. 여섯째, 합병 등의 재편행위시의 특수한 신주발행으로 인한 자본금 및 자본준비금의 계상에 대하여 통일된 기준을 입법적으로 정할 필요가 있다.

      • KCI등재

        청산회사의 구조조정능력

        권기범 한국경영법률학회 2007 經營法律 Vol.18 No.1

        【Zusammenfassung】 Umstrukturierungsfähigkeit der Abwicklungsgesellschaft Kwon, Kiboum Der Beitrag behandelt die sogenannte Umstrukturierungsfähigkeit (Verschmelzungs-, Spaltungs- und Unternehmensübertragungsfähigkeit usw.) einer aufgelösten Aktiengesellschaft(Abwicklungsgesellschaft). Ansatzpunkte sind der Rechtsbegriff, die Rechtsnatur(Identitätstheorie) und vor allem die Rechtsfähigkeit der Abwicklungsgesellschaft. Dabei wird insbesonders die Zweckänderung der Abwicklungsgesellschaft betont, denn die Zweckänderung eine entscheidende Rolle spielen soll :zwar nach Rechtssprechung und heißender Meinung ist die Rechtsfähigkeit der Abwicklungsgesellschaft streng auf dem Liquidationszweck beschränkt. Danach werden erläutert : daß die Unternehmensübertragung der Abwicklungsgesellschaft nur im Bereich der Abwicklungszweck zulässig ist, aber dagegen daß weder die Share-Exchange noch der Formwechsel jedennfalls vereinbar mit dem Liquidationszweck ist. Aufgrund §174 Abs.3 Koreanisches Handelsgesetzbuch(als ‘KHGB' abgekürzt) ist fraglos zulässig die Verschmelzung, an der sich eine Abwicklungsgesellschaft als übertragende Gesellschaft beteiligt. Dabei bedarf es kein Fortsetzungsbeschluß im Sinne von §519 KHGB. Nicht gerelt ist der Fall, daß sich die neue Gesellschaft in Auflösung befindet. Mit der Erwägung des Regelungszweck von §174 Abs.3 KHGB soll es bejaht werden. Ähnliches gilt für die Spaltungen. Übertragende Gesellschaften können bei einer Spaltung wie bei der Verschmelzung auch Abwicklungsgesellschaften sein, solange mit der Verteilung des Vermögens unter den Aktionären noch nicht begonnen wurde. Ein Fortsetzungsbeschluß der Abwicklungsgesellschaft ist gar nicht erfoderlich. Abwicklungsgesellschaften können aber nicht übernehmende Gesellschaften bei einer Spaltung sein. Schlließlich wird argumentiert, daß die weitere Umstrukturierungsfähigkeit einer Abwicklungsgesellschaft auch nur auf die Vereinbarkeit mit dem Liquidationszweck angewiesen sein soll.

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