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Langerhans세포 조직구증의 세침흡인 세포학적 소견 - 1 예 보고 -
곽정자,진소영,이동화,Kwak, Jeong-Ja,Jin, So-Young,Lee, Dong-Wha 대한세포병리학회 1993 대한세포병리학회지 Vol.4 No.2
Langerhans cell histiocytosis or histiocytosis X is a disease of unknown etiology characterized by proliferation of mature histiocytes. While a few descriptions of the cytologic features of eosinophilic granuloma ocurring in the bone have been published, reports of cytologic findings of lymph node-based Langerhans cell histiocytosis are very rare. We report the cytologic findings of a case of Langerhans cell histiocytosis diagnosed by fine needle aspiration cytology from the left supraclavicular and right inguinal lymph nodes in a 65-year-old male. Cytologic smears showed characteristic reticuloendothelial cells which have elongated, folded, grooved nuclei and abundant pale cytoplasms. Particularly, nuclei were highly irregular and multilobated. A few mitotic figures were present. The cytologic diagnosis was confirmed by tissue biopsies from the left supraclavicular and right inguinal lymph nodes. Proliferation of histiocytes were also present in the skin. Immunohistochemistry for S-100 protein, vimentin, $\alpha1-antichymotrypsin$ and lysozyme showed positive staining. Electron microscopy disclosed Birbeck granules.
대학 축구선수의 항산화 물질 정맥투여가 근 손상 회복능력 및 실험관 반응에 미치는 영향
곽정자(Jung-Ja Kwak),최현민(Hyun-Min Choi),김효철(Hyo-Chul Kim),정재우(Jae-Woo Chung),김종경(Jong-Kyung Kim),노호성(Hosung Nho) 한국생활환경학회 2012 한국생활환경학회지 Vol.19 No.2
This study was designed to investigate cardiovascular responses and the recovery from muscle damage after the anti-aging intravenous therapy (AAIT) (once in 2 days, total 14 treatments) in 10 college soccer players. The hemodynamic responses and muscle damage fatigue factors were assessed before and after the AAIT treatment. Muscle damage was induced with 50 min downhill running at the intensity of 75% of VO₂max). The cardiovascular responses were measured by a non-invasive device Physio flow during exercise. After the treatment, There were no statistical differences in the levels of both La and VO₂max levels, while the rapid recovery occurred in the level of the GOT, CK, and ammonia compared to before the treatment (from 30.1±3.01 to 23.7±2.22 U/L; from 277±36.92 U/L to 174.2±40.8 U/L; 113.0±6.13 ug/dL to 75.2±2.92 ug/dL, respectively). Total vascular conductance, stroke volume, and cardiac output were significantly improved after the MIT treatment. Thus, the results indicated that the AAIT treatment may increase oxygen delivery to active skeletal muscle and improve the recovery from muscle damage. Our study suggests that the AAIT treatment could enhance exercise performance and intervene muscle damage in athletes during intense exercise.
16주간의 자전춤 참여가 중년비만고혈압여성의 관상동맥위험인자에 미치는 영향
곽정자(Kwak Jung-Ja),김종경(Kim Jong-Kyung),최현민(Choi Hyun-Min),노호성(Nho Ho-Sung) 한국체육과학회 2008 한국체육과학회지 Vol.17 No.2
It is generally known that cardiovascular and metabolic diseases such as hypertension, diabetes, hyperlipidemia increase morbidity and mortality in postmenopausal women. This study investigated the effects of Jajun-Dance to coronary heart disease of middle age women with hypertension. Thirteen sedentary women (55.8±5.2 yrs) were recruited for this study, and completed 16 weeks of Jajun-Dance program. All subjects were diagnosed as essential hypertension patients. Blood-sugar level (FBG), total cholesterol (TC), triglyceride (TG), systolic blood pressure (SBP), diastolic blood pressure (DBP) and visceral fat area (VFA) were measured. The Jajun-Dance program included 10 minutes warm up (exercise for flexibility), 40 minutes Jajun-Dance, and 10 minutes cool down. The subjects participated in Jajun-Dance program three times a week. Exercise was maintained at exercise intensity corresponding to rating of perceived exertion (RPE) 13-15. The results showed that FBG, SBP, and DBP (6.0 ㎜Hg) were significantly decreased after Jajun-Dance program. TG and VFA tended to decrease, but there were no significant differences. This study suggests that hypertensive middle-aged women could modify coronary risk factors with regular exercise, and that the aerobic Jajun-Dance program could effectively reduce high blood pressure.
이인자;서효신;곽정자;이세라;황은섬;이보라 중앙대학교 의과대학 간호학과 간호과학연구소 2009 중앙간호논문집 Vol.13 No.-
Purpose: The objectives of this study are to examine the effects of balance taping on dysmenorrhea in clinical nurses. Method: Clinical nurses were informed about a balance taping by an investigator who was trained with a 1-day education about it. On the date of menstrual onset. a balance taping was applied to clinical nurses. Prior to the application of balance taping, one hour after it. four hours after it. eight hours after it. 12 hours after it and 24 hours after it. scores indicating dysmenorrhea were measured. Result: Following the application of balance taping, changes in dysmenorrhea were evaluated. According to this, scores indicating dysmenorrhea were 6.57 prior to the application of balance taping, 4.74 at one hour after it, 3.93 at four hours after it, 3.50 at eight hours after it, 2.98 at 12 hours after it and 2.50 at 24 hours after it. These results indicate that scores indicating dysmenorrhea were gradually decreased with time to a statistically significant extent(p=.000). Conclusion: Balance taping is effective in reducing dysmenorrheal in clinical nurses.
이인자;서효신;최현주;반영란;양숙명;김진;곽정자 중앙대학교 의과대학 간호학과 간호과학연구소 2006 중앙간호논문집 Vol.10 No.-
Purpose : The study was designed to investigate the Effects of Hand Massage on the reduction of pre-operative patient’s anxiety. Method : The subjects of this study were the patients expecting an operation in the operating roαn. The experimental treatment was carried out according to the Hand Massage Protocol, developed by Snyder and interpreted by Cho. The visual analog scale as well as the blood pressure, pulse were used to assess the level of anxiety. The data were analyzed using the SPSS/PC+ program. Result : 1. The experimental group provided with a hand massage was show lower score for the pre-operative anxiety than the control group not provided with it’(p<.05). 2. The experimental group provided with a hand rnassage was pre-operative systolic blood pressure lower than the control group not provided with it(p<.05). 3. The experimental group provided with a hand rnassage was pre-operative diastolic bloodpressure lower than the control group not provided with it(p<.05). Conclusion : A hand massage may be useful for reducing anxiety of pre-operative patients.
Ki-1양성 대세포림프종의 세침흡인 세포학적 소견 - 1예 보고 -
권계현,곽정자,진소영,이동화,Kwon, Kye-Hyun,Kwak, Jeong-Ja,Jin, So-Young,Lee, Dong-Wha 대한세포병리학회 1993 대한세포병리학회지 Vol.4 No.2
Ki-1 lymphoma is a sort of high grade large cell lymphoma and defined on the basis of the reactivity of the tumor cells with monoclonal antibody Ki-1. On fine needle aspiration cytology, the reported case is rare and the differential diagnosis is not easy, especially from undifferentiated carcinoma and Hodgkin's lymphoma. We experienced a case of fine needle aspiration cytology of Ki-1 positive large cell lymphoma in a 61-year old male patient. Fine needle aspiration cytology from the cervical lymph node disclosed hypercellular smears with large single cells on polymorphous lymphoid background. The tumor cells had abundant dense cytoplasm and large nuclei with Irregular profiles. Although most cells were mononuclear binucleated and multilobed/multinucleated cells were also seen Immunohistochemistry was done and revealed strong positive staining for Ki-1 antigen.