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Acetic-acid로 대장염을 유발한 생쥐에 투여한 만년환의 치료효과
공원호,김범회,김원일 대한한방내과학회 2023 大韓韓方內科學會誌 Vol.44 No.6
Objectives: This study is designed to verify the effects of Mannyeon-hwan (MNH) on acetic acid-induced colitis in rats. Methods: Colitis was induced in male Sprague-Dawley rats weighing approximately 250 g by injecting acetic acid through the anus. The rats were classified into four groups: normal group, acetic acid (AA) group, AA+MNH (L) (low concentration) group, and AA+MNH (H) (high concentration) group. The body weight, visual evaluation of the colonic mucosa, anatomical histological changes, and changes in the expression of cytokines in the colon tissue were compared and analyzed. Results: Compared with the normal group, weight loss was observed in mice induced with colitis. Compared with the AA group, weight loss recovery occurred in the AA+MNH (L) and AA+MNH (H) groups, and significant changes were observed after the sixth day. In the visual evaluation of the colonic mucosa, a significant decrease in damage indicators was observed in the AA+MNH (L) and AA+MNH (H) groups compared with the AA group. In terms of anatomical histological changes and changes in the expression of tumor necrosis factor-α and interleukin-6 in colon tissue, a significant decrease was observed in the AA+MNH (L) and AA+MNH (H) groups compared with the AA group. A more pronounced decrease was observed in the AA+MNH (H) group compared with the AA+MNH (L) group. Conclusion: The effects of MNH on colitis were confirmed through research. MNH can be used as a first-line treatment for patients complaining of colitis who visit oriental medicine clinics.
공원호,남우진,김보성,박여빈,박윤령,백지원,김원일 대한한방내과학회 2020 大韓韓方內科學會誌 Vol.41 No.2
Objectives: This case report presents the management of a paralytic ileus patient who was diagnosed with Soyangin. Methods: The patient was treated with Korean herbal medicine (Jihwangbaekho-tang, Hyeongbangsabaek-san, Ganghwajihwang-tang), acupuncture, and moxibustion therapy. Results: After undergoing Korean medical treatment, the patient's complaints of symptoms such as constipation, dyspepsia, anorexia decreased and improvements were shown on X-ray. Conclusions: This case report shows that Korean medical treatment is effective for treating paralytic ileus.
공원호,백지영,박여빈,백지원,진준수,손경우 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.5
Objective: This case reports the management of a chronic pyelonephritis patient treated with Hyeonsamjihwang-tang. Methods: The patient suffered from swelling and fatigue and was diagnosed with Soyangin Mangeum-syndrome. The patient was treated with Hyeonsamjihwang-tang for a 40 day period. Hematology, urinalysis, and the numerical rating scale were used to evaluate the effects. Results: After treatment with Hyeonsamjihwang-tang, the patient’s complaints of symptoms decreased, and improvements were shown in hematology and urinalysis. Conclusions: Hyeonsamjihwang-tang has an effect on patients with chronic pyelonephritis.
공원호,김원일,Kong, Won-ho,Kim, Won-ill 대한한방내과학회 2021 大韓韓方內科學會誌 Vol.42 No.5
Objectives: This study examined cases of patients with palpitations treated with Gami-ondam-tang. Methods: The patients were treated with Gami-ondam-tang and changes in their symptoms were assessed using a self-reported numeral rating scale (NRS) score. Results: Following treatment, the patients' palpitations and accompanying symptoms (e.g., insomnia, hot flushes, dyspepsia, and depression) improved. The study investigated 14 first occurrences and 10 subsequent recurrences. In the subsequent recurrent cases, compared to the first occurrence cases, the symptoms according to the NRS score were not severe, and the treatment period was shorter. Conclusions: The results showed that Gami-ondam-tang is effective for treating palpitations and accompanying symptoms.