뇌졸중의 위험요인에 대한 환자-대조군연구 -과거병력, 생활습관, 혈청지질 및 비만요인을 중심으로-

고성규,정용수,박경훈,부송아,Ko, Soeng-Gyu,Jung, Yong-Soo,Park, Kyoung-Hoon,Bu, Song-Ah 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.3

Objects: The purpose of this case-control study was done to examine the relationship between stroke prevalence and the anthropometric indices(body mass index(BMI), modified Broca's method(Broca's index), waist circumference(WC), waist-hip ratio(WHR)), dyslipidemia, past medical history(heart disease, hypertension, diabetes mellitus(DM)), life-style factors(smoking, drinking) in Korean adults. Methods : The study group consisted of neurologically confirmed 116 stroke patients as the case group and 116 non-stroke patients as control group. Obesity were defined as $BMI{\geq}25kg/m^2,\;Broca's\;index{\geq}30%$, WC >94cm in male and WC >80cm in female, $WHR{\geq}0.9$ in male and $WHR{\geq}0.8$ in female. Oyslipidemia were defined as total $cholesterol{\geq}200mg/dl,\;triglyceride{\geq}200mg/dl,\;HDL-cholesterol {\leq}35mg/dl,\;LDL-cholesterol{\geq}160mg/dl$. Information on life-style factors and past medical history was obtained from personal interview. The analysis of the data was done by means of chi-square test(Pearson's chi-square test, Fisher's exact test) and student t-test. Results: The results were as follow. In the study group: Hypertension had a 4:05 odds ratio, Broca's $index{\geq}30%$ had a 1.98 odds ratio, WC >94cm in male had a 2.17 odds ratio, WC >80cm in female had a 2.80 odds ratio, $WHR{\geq}0.9$ in male had a 4.66 odds ratio, $WHR{\geq}0.8$ in female had a 5.35 odds ratio, but heart disease, DM, life-style factors, serum lipid and 8MI had no direct relationship with odds ratio(nonsignificant). By student t-test, risk factors for stroke were found to be total cholesterol(p=0,025), LDL-cholesterol(p=0.013), WC(p=0.000) and WHR(p=0.000). Conclusions: This study suggests that people should be advised to control hyperlitension, hyperlipidemia and obesity since these carry a risk of stroke.

생활폐기물 소각시 요구되는 요소수의 대체물질로 음식물 폐수 속의 암모니아 적용에 관한 연구

고성규,이영신,조용균 유기성자원학회 2012 유기물자원화 Vol.20 No.4

This study examined for possibility of the food wastewater incineration treatment method as one of overland treatment method by incineration through liquefied spray of food wastewater when incinerating domestic wastes under operation and for the relationship, etc of air discharge material discharged in incineration, and the results of study are as follow: The food wastewater as one of overland treatment method was analysed 94-96% of moisture contents. Temperature of incinerator outduct during mixed incineration of food wastewater with MSW was average 897℃ and incineration of only MSW was 925℃. Temperature of the mixed incineration of food wastewater was dropped about 28℃ by incineration of only MSW. Concentration of nitrogen oxides(NOx) among air discharge gases was studied by 50ppm, 46ppm when inputting 200ℓ/hr, 300ℓ/hr into the incinerator as the quantity of food wastewater. In the mixed incineration of food wastewater, generation speed of scales in the inside of a tubular exhaust gas boiler became rapid and the scale generation quantity became large but the exhaust gas boiler normally operated since scales were removed in cleaning of the tube with a compressive air cleaning facility and there was no opening clogging phenomena in a filter cloth of the filtering dust collector. The overland treatment method, not ocean dumping of food wastewater can be proposed as a technology since mixed incineration of food wastewater with MSW in the existing domestic waste incineration plant is possible, and operation costs of the incineration facility were reduced since use of chemicals such as ammonia and urinary hydrogen ion excretion, etc used in incineration facilities for removing nitrogen oxides(NOx). 본 연구는 음식물류 폐기물의 처리과정에서 발생하는 음식물류 폐수를 생활폐기물 소각시설에서 생활폐기물과 음식물류폐수를 혼합하여 소각처리 방법과 소각시 음식물류 폐수를 이용한 질소산화물 제거 및 배출가스의 영향등을 조사하였다. 해양투기용으로 발생된 음식물류폐기물 폐수는 성상이 94-96%의 함수율을 갖고 있다. 음식물류폐기물 폐수를 주입하였을 때 소각로 출구 온도는 897℃이였으며, 평상시는 925℃로 약 28℃도 떨어졌다. 음식물류폐기물 폐수를 각각 200ℓ/hr, 300ℓ/hr 투입시 질소산화물의 평균배출농도는 각각 50ppm, 46ppm 이었다. 연관식 폐열보일러는 음식물류 폐수의 투입량이 많을수록 튜브 막힘 현상이 있었으며, 막힘 튜브는 압축공기를 이용한 튜브 청소로 원상태를 유지 할 수 있어 연속적 소각에는 방해가 되지 않았다. 유기성 폐기물인 음식물류 폐수의 자원화 처리방법과 더불어 기존 소각시설을 이용한 소각처리가 육상처리의 한 방법으로 자리매김 할 수 있으며, 소각시 배출가스의 질소산화물이 제거됨으로써 질소산화물 제거용 암모니아, 요소수 등 화학약품비용 절감하는 효과도 있는 것으로 나타났다.

인공신경망을 활용한 동착강도 예측

고성규,최창호,신휴성 한국지반공학회 2011 한국지반공학회논문집 Vol.27 No.11

동착강도는 동토지반 말뚝기초 설계시 지지력을 결정하는 주요 설계정수이다. 동착강도는 동결온도, 구속응력, 말뚝표면 특성, 토사종류 등 다양한 인자들에 의해 동시다발적인 영향을 받는 것으로 보고되고 있다. 하지만 동착강도에 대한 연구는 소수의 인자들만 반영할 수 있는 실험연구를 중심으로 수행되어온 경향이 있으며, 설계정수로서 동착강도를 산정하기 위한 방법들은 동결온도, 말뚝재료 등의 주요 인자들만을 고려할 수 있는 한계가 있어 왔다. 본 연구는 인공신경망 이론을 동착강도 산정에 활용함으로서 다양한 영향인자 조건에서 동착강도를 예측할 수 있는 방안을 모색하기 위한 목적으로 수행되었다. 인공신경망 학습을 위하여 총 5종류의 연구사례로부터 137개의 자료를 수집하였으며, 그 중 100개를 학습자료로, 37개를 실증자료로 구분하였다. 연구결과 단계적 인공신경망 학습을 통하여 동착강도 산정 시 다양한 영향인자를 다차원적으로 고려하여 예측하는 방법이 병행되어야 할 필요성을 확인하였으며, 5개 영향인자를 동시에 고려하여 동착강도를 예측할 수 있는 신뢰성 높은 학습결과를 도출 및 검증하였다. 또한, 매개변수 연구결과 동착강도는 동결온도와 말뚝재료의 변화에 가장 민감하게 반응하는 것으로 나타났고 수직응력에 의한 영향은 일부 온도구간에서만 뚜렷하게 나타나며 토사종류와 재하속도의 변화에 따라 동착강도가 증가하는 경향이 변화하는 특성을 나타내었다.

비만지표와 혈청지질 및 혈압과의 관련성

고성규,Ko, Seong-Gyu 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.3

Objective : To assess the relationship and prevalence rate among hypertension, dyslipidemia and the four commenest anthropometric measurements for obesity(body mass index(BMI), waist-hip ratio(WHR), waist circumference(WC) and body fat) in Korean adults. Methods : We studied the cross-sectional association of the anthropometric indicies and hypertension, dyslipidemia in 70 Korean adults. Hypertension was defined as blood pressure ${\ge}160/95$mmHg and classification of JNC IV, Dyslipidemia were defined as total cholesterol ${\ge}200$ mg/dl, HDL-cholesterol ${le}35$ mg/dl, LDL-cholesterol ${\ge}160$ mg/dl, triglyceride ${\ge}200$ mg/dl. Infromations on life-style factors were obtained from personal interview. Results : BMI and WHR, BMI and WC, BMI and Fat(%), WHR and WC, WC and Fat(%) had high partial correlation coefficients after age adjustment. BMI and Systolic Blood Pressure had r=0.385 coefficients, WHR and HDL-cholesterol had r=-0.360 coefficients. All four anthropomtric indicies and hypertenstion groups by JNC IV classsification had signifiant differences in women, but only fat(%) and hypertension had significant difference in men. In women, in the relationship of four anthropomtric indicies and serum lipids, total cholesterol ${\ge}200$ mg/dl group with fat(%) had a signifiant difference for normal cholesterol group, and also the group of HDL-cholesterol ${\le}$ mg/dl with WC had significance. But in men, there were no significant differences in all anthropomtric indicies and serum lipids groups. Conclusions : Korean women are more significant than Korean men in the relationship between anthropometric indicies and serum lipids, or blood pressure. But this study's samples are small, so the results are some different with results of other studies. We should study more specifically about anthropometric indicies and serum lipids, anthropometric indicies and blood pressure with many samples.

한국인의 뇌졸중 위험인자로서 커피 음용

고성규,부송아,Ko, Seong-Gyu,Bu, Song-Ah 대한한방내과학회 2002 大韓韓方內科學會誌 Vol.23 No.1

Objectives : To prevent stroke, it is very important to reduce risk factors which might cause stroke. However, previous studies that having investigated coffee consumption associated with stroke reported various results. In addition, there were only a few studies based on the Korean population. Therefore, we studied the association of coffee consumption and the possibility of getting stroke among Koreans. Methods : A case-control study was carried out on 207 cases(stroke patients) and 207 controls(non-stroke patients) in a hospital. Information on characteristics, health habits, dietary habits and coffee consumption were obtained through direct interview by using an organized questionnaire; WHR(Waist-Hip Ratio) was determined through physical examination. The coffee consumption was classified by the average frequency of intake, such as less than 1 cup/day, 2-3 cups/day, more than 5 cups/day). Possible confounding effects of age, sex, smoking and alcohol drinking were controlled by multiple logistically regressive analysis. Results : After adjusting age and sex, coffee consumption significantly increased risk factors of stroke(${\leq}$1 cup/day OR=1.018, 95% CI=0.631-1.644; 2-3 cup/day OR=1.782, 95%CI=1.032-3.079;${\geq}$5 cup/day OR=1.210, 95% CI=0.588-2.490). When other factors were controlled, the risk factors of stroke were associated with alcohol drinking, whereas no significant association was observed with coffee consumption. Conclusion : Coffee consumption is not a major risk factor of causing stroke in this study. Prospective and cohort study on the association between coffee consumption and the possibility of getting strokes among the Korean population will be needed in the future.

한의학회지의 뇌졸중 관련논문을 통한 한의학 연구동향과 질적 메타분석

고성규,Ko, Seong-Gyu 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.2

Objective : There have not been studies on the oriental medicine research trends and qualitative analysis of Korean oriental medicine articles in Korea, particularly in the oriental medicine area. This study's purpose is to appreciate Korean oriental medicine's research trends and assess the quality of the Korean oriental medical journals' level. This study will help upgrade Korean oriental medical journals. Method : We found 93 stroke-related articles in the Journal of Korean Oriental Medicine, published between 1980(Volume 1) and 2001(Volume 45). We surveyed the institutes involved in each study, and the number of people in each study. We seperated by epidemiological study design, the studies into categories. Campbell and Stanley's study design into 6 categories, statistical methods into 13 categories. Next, we assessed the 41 articles by a checklist, which had 10 categories. The quality score was analyzed by survey variables over the period, which were divided by the date of publication: the 1980s, the first half of the 1990s, second half of the 1990s and 2000s. Results : 46.3% od the studies didn't use statistical methods. 56.1%, were case series studies by classification of epidemiological study design, and 53.6% were one-shot case studies designed by Campbell and Stanley's study design. The quality score was 58.33 point 60 is average. In quality level by Browman GP etc.'s, 83.0% of the studies were included in V levels. But, the quality scores were significant by presence of reviewer system, statistical method's usage, and over the period. Conclusion : The Journal of Korean Oriental Medicine needs to improve the quality its articles. To improve the quality of oriental medicine related articles, the following are necessary: working together, joint work of inter-educational system, strengthening of reviewer system, use of statistical methods, and consulting to the expert of research at the stage of study design.

승마체험자의 여가제약이 제약-협상과 행동의도에 미치는 영향 연구

고성규,김미영,이충기 한국호텔관광학회 2019 호텔관광연구 Vol.21 No.4

본 연구의 목적은 승마체험자를 대상으로 여가제약과 제약-협상 및 행동의도 간의 영향관계를 구조 방정식 모델을 이용하여 분석하고자 한다. 이를 위하여 서울, 경기도, 대구, 경상북도, 제주도에서 승마체험자를대상으로 현장조사를 실시하였다. 승마체험자를 대상으로 700부의 설문지가 배포되었으며, 최종 490부를실증분석에 이용하였다. 본 연구에서는 승마체험자의 여가제약 요인을 내재적(intrapersonal), 대인적(interpersonal), 구조적(structural)으로 분류하였으며, 제약-협상 요인은 동반성(companion), 탐색성(exploration), 체계성(systemicity)으로 분류하였다. 분석결과 승마체험의 3가지 제약(내재적, 대인적, 구조적)은 모두 승마체험 제약협상에 긍정적인 영향을 미치는 것으로 나타났으며, 승마체험 제약협상의 3가지요인(동반성, 탐색성, 체계성)은 모두 행동의도에 긍정적인 영향을 미치는 것으로 나타났다. 또한, 승마체험제약협상의 3가지 요인(동반성, 탐색성, 체계성)은 승마체험의 3가지 제약(내재적, 대인적, 구조적)과 행동의도 간의 관계에서 매개역할을 수행하는 것으로 나타났다. 이러한 연구결과는 승마체험에 있어서 제약-협상 요인이 여가제약으로부터 승마체험 행동의도를 예측하는데 중요한 역할을 한다는 사실을 시사해준다. 결론에서는 본 연구의 분석결과를 토대로 학술적, 실무적 시사점을 제시하였다.

한의과대학의 예방(사회)의학 관련 교과목의 교육과정 및 표준화방안

고성규,신용철,Ko, Seong-Gyu,Shin, Yong-Cheol 대한예방한의학회 2008 대한예방한의학회지 Vol.12 No.2

The rapid change of the health and medical environment and the globalization of medicine has driven doctors to converge and analyse of new and up-to-date medical information and decide to what to make decision for diagnosis and treatments in clinical practice. Medical environment goes with the changes with social environment such as rapid increase of aging population, changes of disease pattern, formation of new area of experts except doctors, government intervention for the medical system, medical insurance of the charges of medical treatment, a increased desire for human rights. These trends should be adopted rapidly to the education system for the students of medical school. The learning objectives of the preventive medicine was developed in 1995 and underwent necessary revision of the contents to create the first revision in 2006. However, the required educational contents of health promotion and disease prevention have been changed by the new trends of medical education such as PBL and integrated curriculum and the 2006 revision does not satisfy these needs. We formed a task force which surveyed all the Western and Traditional Korean medical colleges to describe the state of preventive medicine education in Korea, analyzed the changing education demand according to the change of health environment and quantitatively measured the validity and usefulness of each learning objective in the previous curriculum. With these results, for the good education for preventive medicine, each Traditional Korean medicine schools need more preventive medicine faculties and teaching assistants and opening of some required subjects such as Yangsaeng and Qigong. And future studies of the learning process and ongoing development of teaching materials according to the new learning objectives should be undertaken with persistence in order to ensure the progress of preventive medicine education.

뇌혈관질환의 신경기능평가 객관화를 위한 표준화방법 연구 91~114

고성규 한국한의학연구원 1998 한국한의학연구원 연구보고서 Vol.- No.-

한방치료의약품의 안전성과 유효성 연구

고성규 대한한방내과학회 2003 大韓韓方內科學會誌 Vol.24 No.3