작은소진드기(Haemaphysalis longicornis)의 형태학적 연구 : 표면 미세구조 및 침샘조직 The Fine Surface Structures and Salivary Gland

高秉文,李元求,李武三 全北大學校 1993 論文集 Vol.35 No.-

Haemaphysalis longicornis Neumann, 1901 were collected from native cattle and milk cattle, at the Cholla-buk-do province, Korea from June to September 1989. The fine surface structures of each growing stages in H. longicornis were observed by scanning electron microscope(JSM-T330A). Venter, capitulum, hypostome, anus, spiracular plate, ventral integument, festoon, scutum, dorsal integument, claw, legs and Haller's organ were observed. Mean body length is 2,710.2㎛ in unfed males, 3,003.3㎛ in unfed females, l,396.6㎛ in unfed nymphs and 662.6㎛ in unfed larvae. Hypostome dentition is usually 5/5 in adult, 3/3 in nymph and 2/2 in larva. Light microscope was used to investigate the histological structures of the salivary gland in unfed female ticks, H. longicornis. As in other species of female ixodid ticks, the salivary glands are consisted of three alveoli, one agranular(type Ⅰ) and two granular(type Ⅱ, Ⅲ).

참진드기(Ixodes nipponensis) 감염 1예

조유정,주종필,정길삼,고병문 대한감염학회 1997 감염 Vol.29 No.1

저자들은 56세의 여자에서 수개월 동안 피하결절로 나타난 Ixodes nipponensis에 의한 감염 1예를 경험하고 문헌 고찰과 함께 보고한다. We report herein an unusual case of tick bite. A 56 year old woman complained of erythematous nodular skin lesion on the left upper chest. An excisional biopsy specimen of the lesion showed darkish-red nodule, in which there was a tick. It was identified as an adult female of Ixodes nipponensis by the scanning electron microscopic examination.

대장과 관련된 경혈들의 신경해부학적 연구희

이창현,고병문,강창수,이광규,이상룡,이무삼,이봉희 대한체질인류학회 2000 대한체질인류학회 학술대회 연제 초록 Vol.43 No.-

흰쥐 숨뇌의 맨아래구역에서 Phenylalanine처리에 따른 Monosodium Glutamate의 효과

이창헌,고병문,김명순,정옥봉 대한췌담도연구회 2000 대한췌담도연구회지 Vol.5 No.2

흰쥐에서 WGA-HRP와 Pseudorabies virus를 이용한 부고환의 신경로에 대한 연구

이창현,고병문,이봉희,정옥봉 대한해부학회 2001 Anatomy & Cell Biology Vol.34 No.2

肥滿細胞의 脫顆粒에 미치는 pH의 影響에 關하여

조명호,박병건,고병문,전병득,이무삼 의과학연구소 1989 全北醫大論文集 Vol.13 No.2

This study was performed to investigate the effects of pH on the degranulation of mesenteric and peritoneal mast cells induced by compound 48/80 in vivo and in vitro, and to determine the optimal dosage of compound 48/80 for the mast cell degranulation in various pH. Results were as following: 1. In vivo study using mesenteric mast cells : the effect of compound 48/80(1㎍/ml) on mast cells was markedly increased in pH 7.8. 2. In vitro study using peritoneal mast cells: the onset time of degranulation of mast cell induced by compound 48/80(0.33㎍/ml) was shorter in pH 7.2 and 7.8 than those in pH 5.5, 6.4 and 8.5. Above results suggested that response of mast cell to compound 48/80 was rapidly degranulated in pH 7.2 and pH 7.8.

烏貝散이 흰쥐 胃의 Gastrin, Histamine, Somatostatin 면역반응세포에 미치는 영향

이시섭,나현욱,고병문,이광규,이창현 대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.5

To investigate the elects on the administration of Opae-san in rats. Opae-san (500mg/day) and omeprazole(10mg/day) were administration with stomach tube for 4 weeks and 8 weeks. This experiment were investigated numerical change of immunoreactive cells of gastric, histamine and somatostatin in rat stomach mucosa by the immunohistochemical method. The results were as follows : 1. In Opae-san administration group for 4 weeks, the number of gastric immunoreactive cells were increased in one and a half times than that of control group. In omeprazole administration group for 4 weeks, the number of gastric immunoreactive cells were increased in four times than that of control group. In Opae-san administration group for 8 weeks, the number of gastric immunoreactive cells were increased four times than that of control group. In omeprazole administration group for 8 weeks, the number of gastrin immunoreactive cells were increased in six times than that of control group. 2. In Opae-san administration group for 4 weeks, the number of histamine immunoreactive cells were increased in two times than that of control group. In omeprazole administration group for 4 weeks, the number of histamine immunoreactive cells were increased in six times than that of control group. In Opae-san administration group for 8 weeks, the number of histamine immunoreactive cells were increased three times than that of control group. In omeprazole administration group for 8 week, the number of histamine immunoreactive cells were increased in seven times than that of control group. These results suggest that Opae-san extracts inhibit the secretion of gastric acid and this extract use to therapeutic herb of gastric disorders related to the hyperacidity and gastric ulcer.

내분비기관으로서의 심방의 형태학적 특징에 관한 연구 - Ⅱ. 흰쥐의 심방 내강 및 내표면 구조

이무삼,두홍서,고병문,강경진,정우송,박병건,이창현 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.2

二陳湯 전탕액이 흰쥐 위의 Gastrin, Histamine, Somatostatin 면역반응세포에 미치는 영향

최정우,이창현,고병문,이광규 대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.4

To investigate the effects on the administration of Yijin-tang extract in rats. Yijin-tang extract(4ml/day) and omeprazole(10mg/day) were administration with stomach tube for 4 weeks and 8 weeks. This experiment were investigated regional distriburion and frequency of immunoreactive cells of gastrin, histamine and somatostatin in rat stomach mucosa by the immunohistochemical method. The results were as follows:1. In Yijin-tang extract administration group for 4 weeks, the number of gastrin immunoreactive cells were increased in two times than that of control group. In omeprazole administration group for 4 weeks, the number of gastric immunoreactive cells were increased in four times than that of control group. In Yijin-tang extract administration group for 8 weeks, the number of gastric immunoreactive cells were not significant change compared with that of 4 weeks administration group. In omeprazole administration group for 8 weeks, the number of gastrin immunoreactive cells were increased in six times than that of control group. 2. In Yijin-tang extract administration group for 4 weeks, the number of histamine immunoreactive cells were increased in three times than that of control group. In omeprazole administration group for 4 weeks, the number of histamine immunoreactive cells were increased in five times than that of control group. In Yijin-tang extract administration group for 8 weeks, the number of histamine immunoreactive cells were increased 4 times than that of control group. In omeprazole administration group for 8 weeks, the number of histamine immunoreactive cells were increased in seven times than that of control group. These results suggest that Yijin-tang extract inhibit the secretion of gastric acid and this extract use to therapeutic herb of gastric disorders related to the hyperacidity and gastric ulcer.

흰쥐에서 WGA-HRP와 pseudorabies virus를 이용한 정관의 신경로에 대한 연구

이창현,정옥봉,고병문,이봉희,김수명,김인식,양홍현,Lee, Chang-Hyun,Chung, Ok-Bong,Ko, Byung-Moon,Lee, Bong-Hee,Kim, Soo-Myung,Kim, In-Shik,Yang, Hong-Hyun 대한수의학회 2003 大韓獸醫學會誌 Vol.43 No.1

This experimental studies was to investigate the location of PNS and CNS labeled neurons following injection of 2% WGA-HRP and pseudorabies virus (PRY), Bartha strain, into the ductus deferens of rats. After survival times 4-5 days following injection of 2% WGA-HRP and PRV, the rats were perfused, and their brain, spinal cord, sympathetic ganglia and spinal ganglia were frozen sectioned ($30{\mu}m$). These sections were stained by HRP histochemical and PRY inummohistochemical staining methods, and observed with light microscope. The results were as follows ; 1. The location of sympathetic ganglia projecting to the ductus deferens were observed in pelvic ganglion, inferior mesenteric ganglion and L1-6 lwnbar sympathetic ganglia. 2. The location of spinal ganglia projecting to the ductus deferens were observed in T13-L6 spinal ganglia. 3. The PRY labeled neurons projecting to the ductus deferens were observed in lateral spinal nucleus, lamina I, II and X of cervical segments. In thoracic segments, PRY labeled neurons were observed in dorsomedial part of lamina I, II and III, and dorsolateral part of lamina IV and V. Densely labeled neurons were observed in intermediolateral nucleus. In first lumbar segment, labeled neurons were observed in intermediolateral nucleus and dorsal commisural nucleus. In sixth lumbar segment and sacral segments, dense labeled neurons were observed in sacral parasympathetic nuc., lamina IX and X. 4. In the medulla oblongata, PRV labeled neurons projecting to the ductus deferens were observed in the trigeminal spinal nuc., A1 noradrenalin cells/C1 adrenalin cells/caudoventrolateral reticular nuc., rostroventrolateral reticular nuc., area postrema, nuc. tractus solitarius, raphe obscurus nuc., raphe pallidus nuc., raphe magnus nuc., parapyramidal nuc., lateral reticular nuc., gigantocellular reticular nuc.. 5. In the pons, PRV labeled neurons projecting to the ductus deferens were ohserved in parabrachial nuc., Kolliker-Fuse nuc., locus cooruleus, subcooruleus nuc. and AS noradrenalin cells. 6. In midbrain, PRV labeled neurons projecting to the ductus deferens were observed in periaqueductal gray substance, substantia nigra and dorsal raphe nuc.. 7. In the diencephalon, PRV labeled neurons projecting to the ductus deferens were observed in paraventricular hypahalamic nuc., lateral hypothalamic nuc., retrochiasmatic nuc. and ventromedial hypothalamic nuc.. 8. In cerebrum, PRV labeled neurons projecting to the ductus deferens were observed in area 1 of parietal cortex. These results suggest that WGA-HRP labeled neurons of the spinal cord projecting to the rat ductus deferens might be the first-order neurons related to the viscero-somatic sensory and sympathetic postganglionic neurons, and PRV labeled neurons of the brain and spinal cord may be the second and third-order neurons response to the movement of smooth muscles in ductus deferens. These PRV labeled neurons may be central autonomic center related to the integration and modulation of reflex control linked to the sensory and motor system monitaing the internal environment. These observations provide evidence for previously unknown projections from ductus deferens to spinal cord and brain which may be play an important neuroanatornical basic evidence in the regulation of ductus deferens function.