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손흥규,김성오,이제호,계희란 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.1
치아발육시기의 항암치료는 치아에 영향을 줄수 있으며 이에 대한 예상 및 적절한 치료계획수립이 필요하다. 본 증례에서 환자의 왜소치는 항암 화학요법과 관련되어 발생한 것으로 추정되며, 이에 대한 장기적 관찰 및 치료가 필요할 것으로 사료된다. With the improved cure rates for childhood malignant conditions in the past decade, late effects of cancer therapy must be recognized to minimize their impact on the quality of life in long-term survevors. Chemoradiation therapy is a major part of pediatric oncology treatment and is implicated in causing tooth agenesis, microdontia, root shortening, early apical closure, and coronal hypocalcification. Dental development may be affected by illness, trauma, chemotherapy, or radiation therapy at any point prior to complete maturation. Treatment given during the first 3.5 years of life was more likely to affect the dental lamina and crown formation and result in a small tooth. Dental treatment affected by chemoradiation damage to developing teeth includes orthodontic tooth movement, prosthetic abutment consideration, periodontal health, space maintenance, requirement for home fluoride regimens to protect hypomineralized teeth, and enodontic procedures. Dental abnormalities are common in patients treated for cancer, and these children require aggressive dental follow-up. Meticulous surveillance may facilitate detection of abnormalities, enabling the dental practitioner to intervene earlier in promoting a more aggressive regimen of oral care, thus reducing the morbidity associated with dental sequelae of oncotherapy, specifically preiodontal disease and malocclusion. In this case, we report microdontia of all premanent second premolar and second molar in an 8 year old boy treated with chemotherapeutic agents during period of active dental development(14 months to 38 months of age).