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        체외수정 및 배아이식:Ohio State University의 시술과정을 중심으로

        강길전,Kang, Kil-Chun 대한생식의학회 1989 Clinical and Experimental Reproductive Medicine Vol.16 No.2

        This is a report concerning IVF-ET program and its outcomes of the reproductive center of the Ohio State University(OSU). The pregnancy rate/laparascopy in the OSU reproductive center was average 12.2%. However, the fertilization rate was lower than other reporters. The other problem of the OSU reproductive center was that there was no success in the field of cryopreserved embryo and donor embryo. Therefore, many aspects such as hyperstimulation protocol, culture systems, and embryo transfer technique should have to be reevaluated in order to enhance the outcome of IVF-ET program in the OSU reproductive center.

      • 체중에 따른 다낭성난소 증후군 환자의 혈중 인슐린에 관한 연구

        강길전 충남대학교 의학연구소 2001 충남의대잡지 Vol.28 No.2

        Objective : This study was attempted to evaluate the serum endocrinologic characteristics and insulin status according to normal body weight and overweight in women with polycystic ovarian syndrome(PCOS). Method : Sixty-eight women were included in this study. Among these study groups, 15 patients were normal weight group and remainder 53 patients were overweight groups. Serum pituitary hormone, ovarian and adrenal steroid hormone, insulin and serum lipid series were measured on emptying state. Also ovarian volume and total area were measured with transvaginal sonography. Results : In patients with normal-weighted PCOS showed (1) significantly low BMI, (2) significantly low serum LH level, (3) significantly low insulin level, (4) significantly low total cholesterol and triglycerid level, and significantly low ovarian area, compared to over-weighted PCOS group. Conclusion : This study showed that even normal body weight could cause polycystic ovarian syndrome and there is a another line of pathophysiologic pathway. So it was thought that in the future the reason why normal weight also could cause polycystic ovarian syndrome must be evaluated.

      • 난관복원수술의 임상적 고찰

        姜吉田 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

        From February, 1984 to September, 1987, forty-three patients were undertaken microsurgical reanastomosis of the fallopian tubes for reversal of sterilization in the Department of Obstetrics and Gynecology of Chungnam National University Hospital. The clinical data of 43 cases were analyzed and the following results were obtained. 1. Intrauterine pregnancy rate was 65.1% and ectopic pregnancy rate was 4.6% in this study 2. The type of previous sterilization procedure performed (ring, cautery, and Pomeroy) did not influence the pregnancy rate. 3. The age of patients, the time interval from sterilization to the tubal reversal, the final tubal length, and the site of reanastomosis did not influence the pregnancy rate. This study shows that unselected patients would have relatively high success rate in the tubal reanastomosis.

      • 생쥐배자의 체외성숙에 적합한 배양조건에 관한 연구

        강길전 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2

        In the human in vitro fertilization and embryo transfer program a variety of chemically defied culture media are being used for gametes and embryo culture by different centers. Also protein supplement of various types comprising various concentration are commonly used. Furthermore, culture technics including type of culture vessels, amount of used media and embryo density are variable by different centers. However, there has been no study of the relative merits of these variables in embryo culture a single center. In order to clarify this, the study was carried out and the results were as follows. 1. A comparative study of three different media, viz, Ham F-10, Esrle's and TC 199 media has shown no one media to be significantly superior. 2. Amniotic fluid was a more appropriate media for embryos than the media currently in use. 3. The effects of serum supplement in culture medium were positive, comparing to unsupplemented basic culture media. 4. A comparative study of four different serum, viz, fetal cord serum, pregnant woman serum, woman serum and man serum has shown no one serum to be significantly superior. 5. No significant difference was observed when mouse embryos were cultured in media containing 20% or 50% of various type of serum. 6. No significant difference was observed when the embryos were cultured in small drop under paraffin oil, in culture tube, or in culture dish. 7. No significant difference was observed when the embryos were cultured in 1 ml or 2 ml of culture media. 8. Embryo development was improved when a larger groups of embryo were cultured in agiven amount of media.

      • 무월경 환자의 원인 분석

        姜吉田 충남대학교 의과대학 지역사회의학연구소 1983 충남의대잡지 Vol.10 No.2

        A retrospective study was attempted to analyse 22 cases of primary and secondary amenorrheic patients managed at Chungnam University Hospital during about 7 months from April, 1983 to October, 1983. The results obtained were as follows: 1. These patients were able to analyse according to organ defect. Twelve cases (54.5%) were classified to have hypothalamo-pituitary defect, 5 cases were end-organ defect, 4 cases were ovarian defect and 1 case was adrenal gland defect. 2. These patients wee able to analyse according to disease entity. Eight cases (35.4%) were diagnosed to have hypothalamo-pituitary dysfunction, 3 cases (13.6%) were Turner syndrome, 3 cases (13.6%) were Asherman's syndrome, 2 cases (9.1%) were testicular feminization, 2 cases (9.1%) were hypothalamo-pituitary failure and idiopathic hyperprolactinemia, pituitary acidophilic adenoma, premature ovarian failure or congenital adrenal hyperplasia was 1 case, respectively. Accordingly, this study suggested that there were diverse etiologic factors in spite of small number of amenorrheic patients.

      • 산부인과 종양환자의 혈청 Cholesterol및 Triglyceride에 관한 연구

        姜吉田 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2

        To investigate the relation of dietary fat with gynecologic tumor, the serum levels of cholesterol and triglyceride were evaluated in each group of patients with cervical cancer, myoma uteri, adenomyosis, trophoblastic dsiease, dermoid cyst of ovary, serous tumor of ovary, mucinous tumor of ovary and non-neoplastic tumor of ovary during the period from April, 1983 to February, 1986. The results obtained were follows : 1. The mean levels of cholesterol and triglyceride in the control group were 167±29 mg% and 105±43 mg%, respectively. 2. The serum levels of cholesterol in each group of patients with cervical cancer, myoma uteri, adenomyosis, trophoblastic disease, ovarian dermoid cyst, ovarian mucinous tumor and ovarian non-neoplastic tumor were not significant with the control group. 3. The serum levels of triglyceride in each group of patients with cervical cancer, myoma uteri, adenomyosis, trophoblastic disease, ovarian dermoid cyst, ovarian mucious tumor and ovarian nonneoplastic tumor were not significant with the control group. 4. The serum level of cholesterol in patient with ovarian serous tumor was significantly higher than the control group. 5. The serum level of triglyceride in patient with ovarian serous tumor was significantly higher than the control group. Accordingly this study suggests that ovarian serous tumor has a certain relation with serum cholesterol and triglyceride. This relation remains to be solved.

      • 다낭성 난소낭종 증후군의 임상적 연구

        강길전 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

        Twenty-seven patients who showed polycystic ovaries on ultrasound were evaluated in view of clinical characteristics and hormonal profile. Clinically, obesity was the most common finding and oligomenorrhrea was the next. Endocrinically, hypertestosteronism was the most common finding and LH elevation was the next. This study shows that polycystic ovarian syndrome was composed of heterogenous hormonal abnormality.

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