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반복성 기흉(氣胸)을 유발한 원발성 폐(肺) 조직구증-X
강경호,유세화,인광호,구양서,강세용 대한내과학회 1992 대한내과학회지 Vol.43 No.1
Pulmonary histiocytosis X can be associated with disseminated histiocytosis X, but isolated case in the lung parenchyme is rare. We report a case of primary pulmonary histiocytosis X with recurrent pneumothoraces. A 36-year-old man was referred because of recurrent pneumothorax. He had been suffered from dry cough and exertional dyspnea for 4 years. He was a heavy smoker. Plain chest X-ray and chest CT scan revealed thin-walled cysts of various sizes in both lungs. Open lung biopsy was performed. Light microscopic examination revealed proliferation arid infiltration of Langerhans'cells. Immunohistochemically, Langerhans`cells showed strong cytoplasmic staining with S-100 protein and electronmicroscopic examination showed Birbeck granules in Langerhans`cell. He was treated with bleb resection and pleurodesis, but pneumothorax recurred 1 month later.