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Sodium Nitroprusside 와 Prostaglandin E1 을 이용한 유도저혈압이 압수용체반사에 미치는 영향
김익동,정규섭,김인세,강건,김학식 대한마취과학회 1991 Korean Journal of Anesthesiology Vol.24 No.6
This study was Uesigned to evaluate the reflexive heart rate response to acute blood loss during sodium nitroprusside and prostaglandin E₁ induced-hypotension in isoflurane anesthetized dogs. The results were as follows: 1) Reflexive increase in heart rate during induced hypotension was significantly greater in sodium nitroprusside than prostaglandin E₁. 2) Reflexive increase in heart rate during induced hypotension was significantly greater prostaglandin E₁ induced-hypotension than during that wih sodium nitroprusside. From these results, it suggest that prostaglandin E₁ induced-hypotension provides a safer margin than with sodium nitroprusside when rapid bleeding occurs during anesthesia and surgery.
Jewett nail을 이용한 대퇴골 전자부 골절의 치료
김익동,박병철,김풍택,이수영,최영욱,김도수 慶北大學校 醫科大學 1987 慶北醫大誌 Vol.28 No.1
The prime objective in treating the trochanteric fracture is to achieve bony stability at the fracture site by internal fixation as it provide satisfactory reduction and fixation of the fractures allowing early mobilization of the patient thus avoiding general and local complication following this sort of trauma. The operative management of trochanteric fracture using Jewett nail was performed in eighty-three patients who were admitted at the department of orthopedic surgery, Kyungpook National University Hospital from 1978 to 1985. Of eighty-three patients, fifty-five patients were analysed completely. The results were as followed: 1. Of the 83 cases of the trochanteric frature, 56 cases were in man, 27 cases were in female, with peak age at 7th decade. 2. The most common cause of fracture was traffic accident in 34 cases, fall down in 26 cases and shlip down in 23 cases. 3. According to the classification of the intertrochanteric fracture by Tronzo, most common type was type Ⅲ in 30 cases, and in the subtrochanteric fracture by Fielding classification, type Ⅰ in 6 cases, type Ⅱ in 9 cases and type Ⅲ in 6 cases. 4. Of the 83 cases of the trochanteric fractures, reduction with medialization was done in 13 cases. 5. The average time until weight bearing was 7.1 weeks in intertrochanteric fracture and 10.8 weeks in subtrochanteric fracture. 6. The average bony union time was 16.8 weeks in intertrochanteric fracture, and 20.2 weeks in subtrochanteric fracture. 7. Of the 32 cases of unstable intertrochanteric fracture, late varus deformity was noticed with 6.0˚ in cases of anatomical reduction, 4.5˚ in cases of medialization and leg shorteing was 1.0㎝ in cases of anatomic reduction, 1.4㎝ in cases of mediaalization. 8. Complication was encountered in 14 cases. Limping in 9 cases, surgical wound infection in 2 cases, nail penetration into hip joint in 2 cases and refracture in 1 case. 9. By evaluation of overall, result was good in 34 cases, moderate in 18 cases and poor in 3 cases.
骨髓腔內 釘揷入이 骨折治療에 미치는 影響에 관한 實驗的 硏究
金益東 계명대학교 醫科大學 病理學敎室同門會 1987 樂山 鄭在泓 敎授 頌喜 紀念論文集 Vol.S No.-
Fifty-eight rabbits were subjected, to fracture and studied. Linear or segmental fractures at the junction of the middle and distal thirds of both . radii of these animals were made. In all experimental animals a Kirschner wire was inserted intramedullary from the distal end of the right radius. The left radius was not fixed with any internal device and was used as the control side. Animals were sacrificed and studies made at 1 week, 10 days, 2, 3, 4, 5, 8, 12, and 16 weeks. Radiography, microangiography, biochemical, and histological techniques were used. The results were as follows; 1) Radiography: The side with intramedullary fixation formed the periosteal callus earlier than the control side. Though callus formation appeared earlier in segmental fracture, complete healing was somewhat slower than it was in animals with linear fracture. 2) Microangiography: The nutrient artery was normal down to the fracture site on the control side. On the experimentalside. the nutrient artery remained normal down to the most proximal point of the intramedullarynail. As healing progressed, circulation increased by development of new blood vessels at the cortex of the fracture site. This development was more pronounced on the experimental side. 3) Biochemistry: A week after experimental fracture the alkaline phosphatase levels in the blood of the experimental animals increased to more than twice that of the control animals. Serum phosphorus levels were one and one-half times higher than those of the control animals. No remarkable change was observed in serum calcium. There was no difference in bio'"" chemical studies between linear and segmental fractures. After the first week, all blood chemistries studied returned to normal. 4) Histology: Periosteal new bone formation was present at the end of one week. It was more advanced on the experimental side. At no time during the experiment did the intramedullary fixation side lag behind the control side in . healing. In a few cases the healing on the side with fixation was significantly ahead of the control side. Linear fractures healed more rapidly than segmental ones. The conclusion of the experimental study is that: 1) In no case did the use of intramedullary fixation delay bony union. 2) In a few cases the use of intramedullary fixation facilitated bony union.