대뇌 혈관외피세포종 2예보고 : 2 Case report

최용교,천태상,김대조,옥영철,이규웅 대한신경외과학회 1975 Journal of Korean neurosurgical society Vol.4 No.1

Designation and classification of the vascular neoplasms of the brain and meninges have not been established to the satisfaction of all neuropathologists. Angioblastic meningioma, hemangioperiytoma, hemangioendothelioma, cerebellar hemangioblastoma and vascular sarcoma are all graded into each other as judged histologically, and somewhat it resembles some of vascular malformations. The application of electron miscrosccpe to the problem of distinguishing among the vascular tumors of the brain and meninges offers an additional source of information. These two cases of the brain tumors are malignant hemangiopericytoma, but rather one is more satisfactory to designate angioblastic meningioma. All of these tumors were located in the parieto-occipital lobe subcortically and also attached to the falx cerebri. In spite of surgical removal of these tumors, the tumor masses were regrowing very rapidly and needed surgical intervention again 3 months after previous operation.

新生兒에 發生한 巨大한 Sacrococcygeal teratoma 1例 報告

崔龍敎,金大造,朴孝淑,李圭雄 대한신경외과학회 1974 Journal of Korean neurosurgical society Vol.3 No.1

Sacrococcygeal teratoma is a very rare tumor of infancy, the incidence being reported about one in every 20,000 to 40,000 live births. Most of the reported cases of sacrococcygeal teratoma appear in female infants with an incidence of 75 to 90 per cent. The great majority of these neoplasms are benign but the incidence of malignancy is reported to be 25%. Those who had giant sized sacrococcygeal teratoma may caused obstetric complication such as dystocia and stillbirth, and may necessitate early cesarian section. A case of a 3 days old male with giant sacrococcygeal teratoma is reported and mentioned about sucessful surgical management.

Glycocholate가 가토심장 동방결절 및 방실결절세포의 전기생리학적 특성에 미치는 효과

최용교,고상돈,김기순 한양대학교 의과대학 1987 한양의대 학술지 Vol.7 No.1

It has long been known that jaundiced patients show a great tendency to develop bradycardia and hypotension and also that the similar changes in cardiovascular function can be observed following intravenous administration of bile acids into experimental animals. Recently several investigators have demonstrated the electrophysiological effects of some bile acids on cardiac cells. The present study was undertaken to investigate effects of glycocholate on the electrophysiological parameters of rabbit sinoatrial node (SAN) and atrioventricular mode (AVN). The results obtained were as follows: 1. GCA in 0.025% concentration altered maximum diastolic potential (MDP) of central SAN from -71.7 ±2.2mV to -62.6±2.2mV. 2. Following superfusion of central SAN with Tris-Tyrode solution containing 0.05% GCA amplitude of action potential was significantly reduced. And the rate of spontaneous firing (RSF) decreased (from 96.5±8.3/min to 60.3±8.0/min) as well. 3. After superfusion with 0.025% GCA solution action potential duration (as manifested by APD60) of peripheral SAN was prolonged (from 103.0±3.1 ms to 120.0±5.3ms). 4. Following superfusion of peripheral SAN with 0.05% GCA solution amplitude of action potential and RSF decreased significantly whereas MDP was increased (from -76.8±1.7mV to -58.4±5.2mV). 5. GCA (0.05%) increased MDP of AVN cells (from -81.6±1.8mV to -54.4±6.8mV) while it reduced the RSF significantly (from 51.2±3.7/min to 33.6±3.6/min). 6. Electrical asystole was observed in approximately 10% of experimental cases when central or peripheral SAN cells were superfused with 0.05% GCA solution.

고사리(Pteridium aquilinum)가 적출가토 장관운동에 미치는 영향

崔龍敎,辛弘基,金基淳 한양대학교 의과대학 1983 한양의대 학술지 Vol.3 No.2

Toward turning of last century it was known that the bracken fern (Pteridium aquilinum) was poisonous to cattle. An acute bracken poisoning resulting from cumulative effect of toxic substance is characterized by severe anorexia, widespread hemorrhage most often in the interstine and heart and pyrexia with a leucopenia caused by depression of bone marrow activity. A syndrome known as chronic enzootic hematuria frequently found in the cattle in certain areas of the world was associated with urinary bladder tumors. Many workers have reproduced hematuria and bovine urinary carcinomas by feeding the fresh or sun-dried bracken. Also it was indicated that high incidence of stomach cancer in Korea and Japan might partially result from ingestion of bracken fern. An analogy between clinical picture of bracken poisoning and that of radiation damages was suggested by several early works. In a number of different animals thiamine deficiency was also demonstrated as the result of ingesting bracken which was known to contain thiaminases. It appears that little is known on the effect of bracken on the gastrointestinal motility and functions of the cardiovascular system. Therefore the present study was undertaken to elucidate effect of ethanol extract of bracken (PAEE) on the motility of isolated rabbit duodenum. Also studied was the mechanism underlying the changes in motility of isolated intestinal strip by PAEE. The results obtained were as follows: 1. The motlity of isolated intestinal strip was depressed by ethanol extract of bracken. And degreeof deression was generally proportional to dosage of PAEE administered. 2. The depressive action of PAEE on the motility of isolated rabbit duodenum was not significantly affected by acetylcholine, pilocarpine, regitine, propranolol, histamine, atropine and barium chloride.

髓內 類皮囊胞(Intramedullary dermoid syst)를 동반한 先天性 眞皮瘻(congenital dermal siuus) 1예 보고 : Case Report

정준기,최용교,옥영철,이규웅 대한신경외과학회 1975 Journal of Korean neurosurgical society Vol.4 No.2

Congenital dermal sinuses result from a failure of separation of the cutaneous epithelial ectoderm from the neuroepithelial ectoderm along the dorsum of the embryo during the first month of intra-uterine life. These sinus tracts can occur at any level of the cerebro-spinal axis, but are located predominantly in the occipital and lumbosacral regions and occasional cases involving the cervical and thoracic regions. The dermal sinus tract is lined by stratified squamous epithelium and extends from the surface through the deeper tissues into the cranial or spinal cavity, usually ending on the dura or within the dura in conjunction with a terminal epidermoid or dermoid cyst. An intra-medullary epidermoid or dermoid with a dermal sinus is an unusual association. We have been able to find a previously reported coincidence of these malformations although there are many definitive papers on these uncommon entities. We are experienced in one case who are 14 months old boy with a intra-medullary dermoid cyst associated with a congenital dermal sinus at the T₄ level, and reviewed related reports.

양측성 소뇌 결핵종 1예 보고

심성보,김형동,최용교,--,옥영철,이규웅 대한신경외과학회 1975 Journal of Korean neurosurgical society Vol.4 No.2

Hematogeneous spread from tuberculous lesions of other parts of the body represent the origin of intracranial tuberculomas. In most series of the literature, the cerebellum has about two thirds and the cerebral hemispheres about one third of the intracranial tuberculomas. It may occurs as a single lesion, but multiple intracranial tuberculomas varies from 10% to 33% of the cases due to the hematogenous spread. Calcium deposits are rare, occurring in about 6% of cases. Ramamurthi and Varadarajan described the two types of the intracranial tuberculoma; 1. superficial and vascular type, produces early focal signs of increased intracranial pressure. 2. deep and avascular type, accoampained by signs of increased intracranial pressure. We have been experienced in one case of symmetrical and bilateral cerebellar tuberculomas probably originated from the pulmonary lesion.

A giant cell tumor of the thoractic vertebra : Case Report 1예 보고

Park, Choong Kyum,Kim, Hyung Dong,choi, Yong Kyo,Kim, Dae Jo,Ok, Yung Chul,Lee, Kyu Woong 대한신경외과학회 1975 Journal of Korean neurosurgical society Vol.4 No.2

거대세포종양은 대부분 장골에서 발생되나 약 8%가 척추에서 나타난다. 이 종양은 연골성골의 골간 및 골단부에서 주로 발생하며 현미경 소견상 특징적으로 파골세포(osteoclastic cell)나 골수의 거대핵세표(megakaryocytic cell)를 닮은 거대세포를 볼 수 있다. 치료는 종양 실질을 제거하고 방사선 치료를 한다고 한다. 본원 신경외과에서는 22세 여자로서 외상후 증상이 악화되었던 거대세포종양 1예를 경험하였기에 문헌고찰과 함께 보고한다. Giant cell tumors in vertebrae are rarely en-countered in neurosurgery, which was interpreted as a distinctive neoplasm arising from short or long cartilaginous bones at epiphyseal-diahpyseal level. In spite of it's rarity, we experienced one case of giant cell tumor of the thoracic vertebra. A 22 year-old Korean single girl was admitted to our hospital with complaints of back pain. Rerferred to the both lower extremities, paraplegia, and voiding difficulty after fell off an attic. She was operated on total laminectomy because of T-11 vertebral body destruction with collapse and complete obstruction at the level of T-11 vertebra on myelogram. Patho logical diagnosis was verified as a giant cell tumor.

급성 경막하 혈종 100예 분석 보고

전용문,정준기,최용교,김대조,옥영철,이규웅 대한신경외과학회 1975 Journal of Korean neurosurgical society Vol.4 No.2

The authors reported 100 cases of acute subdural hematomas confirmed by operation from Jan. 1972 to Sept. 1975. We discussed the relationship of the type of operation to mortality in acute subdural hematomas. The types of surgical operations were divided in 4 groups. The surgical mortality rate was 19% for frontotemporoparietal craniotomy, 29% for multiple burr holes technique, 42% for craniectomy and 48% for subtemporal decompression with burr holes and total over-all mortality was 36% in our cases. The authors reviewed the literatures described the surgical operative method and it's mortality and so we thought large frontotemporoparietal craniotomy is more valuable method for operation of the acute subdural hematomas.