Aspirin 諸合性에 關한 再考

김정란,박숙자,유영자,박옥운,김정은,노수자,오경희,조연자 梨花女子大學校 藥學硏究所 1962 梨花藥學硏究 Vol.- No.3

부모권력구조에 대한 아동기 경험이 여대생의 성역할 정체감에 미치는 영향 : The Influence of Childhood Experience of Parental Power Structure

김광응,유미숙,조유진 숙명여자대학교 아시아여성연구소 2004 아시아여성연구 Vol.43 No.1

본 연구는 여대생을 대상으로 부모권력구조에 대한 아동기 경험이 성역할 정체감에 어떤 영향을 미치는지를 알아보고자 하였다. 이를 위해 여대생 425명을 대상으로 부모권력구조에 대한 아동기 경험과 성역할 정체감을 측정한 자료를 분석하였다. 본 연구의 결과를 요약하면 다음과 같다. 첫째, 부모권력구조 각 하위요인(가족행사 · 친족관련 권력,자녀교육 권력, 가정경제 권력)에 대해 부우위형과 모우위형의 부모권력을 경험한 여대생은 성역할 정체감 분포에서도 다른 양상을 보였다. 반면 부모권력구조 척도의 전체점수를 합산하여 부우위형과 모우위형으로 부모권력을 구분했을 때 여대생의 성역할 정체감 분포에는 차이를 보이지 않았다. 이는 기존 부모권력 측정도구의 문제점을 지적한 연구자의 비판에 타당성을 더해주는 결과이다. 둘째, 여대생의 성역할 정체감에 영향을 미치는 변인으로 부모권력구조 하위요인 모두를 동시에 고려한 다반응 로짓분석 결과 부모권력구조 하위요인 중 자녀교육 권력과 가정경제 권력이 유의한 변인으로 나타났다. 즉, 자녀교육 권력에서 아버지가 적극적으로 참여하고 의사결정 정도가 높을 때 여대생들의 양성성과 남성성 성역할 정체감 발달 확률이 높은 반면, 가정경제 권력에서는 어머니의 참여와 의사결정 정도가 높을 때 여대생들이 남성성 성역할 정체감을 발달시킬 확률이 높은 것으로 나타났다. 한편, 가족행사 · 친족 관련 권력은 다른 하위요인의 영향을 제거했을 때 여대생의 성역할 정체감과는 관계가 없는 것으로 나타났다. The purpose of this study was to investigate how sex-role identities of female college students were related to their childhood experiences of parental power structure. Questionnaire survey was conducted with 425 female college students regarding their childhood experiences of parental power structure and their sex-role identities. Parental power structure consisted of three subfactors: parental power on family events/relative-related, child education, and home economics. It was found that the female college students formed different sex-role identity dimensions when their experiences of parental power hierarchy were measured individually in subfactors. However, they did not show differences when their experiences of parental power hierarchy were measured as the sum of subfactor scores. This supports the authors' conviction that previous measures are problematic in identifying relationships of parental power structure and children's sex-role identity. In particular, multi-response logit analysis was used in order to take into account of all the subfactors of parental power structure at the same time. As a result, childhood experiences of parental power hierarchy on child education, and on home economy were found to be closely related to the sex-role identities in the female college students. That is, the female college students, whose fathers had power on their children's education through active participation and decision-making, were likely to develop their androgyny and masculinity. On the other hand, those whose mothers had power in home economy were likely to develop masculinity. Furthermore, family events and relative-related parental power were not found to be related to the sex-role identity in female college students when the impacts of other subfactors were eliminated. It is posited that equal or balanced exertion of parental power is critical in the development of adptive and flexible sex-role identity in their children.

활성화 C 단백 내성검사의 정도관리와 한국인의 양성률

이영경,박성섭,이유경,이진숙,함천경,주세익,윤근영,박선양,조한익 대한임상병리학회 1996 대한임상병리학회지 Vol.16 No.6

< 좌장 : 김규언 , 박해심 > ( 15:30 - 16:10 ) : Enhanced expression of glucocorticoid receptor beta messenger RNA in peripheral blood mononuclear cells of asthmatics with acute exacerbation after upper respiratory tract infection

(You Sook Cho),(Chang Keun Lee),(Eun Young Lee),(Jung Hyun Shin),(Hyoung Seouk Ji),(Man Soo Ann),(Bin Yoo),(Hee Bom Moon) 대한천식 및 알레르기학회 ( 구 대한알레르기학회 ) 2001 춘계학술대회 초록집 Vol.2001 No.-

Dilemma of Asthma Treatment in Mild Patients

( You Sook Cho ),( Yeon-mok Oh ) 대한결핵 및 호흡기학회 2019 Tuberculosis and Respiratory Diseases Vol.82 No.3

Inhaled corticosteroids (ICSs) have been widely used as a key medication for asthma control. However, ICSs have been known to cause respiratory infections, such as pneumonia and pulmonary tuberculosis. Consequently, a dilemma exists regarding recommendation of persistent lifetime use of ICSs to mild asthma patients. Short-acting β-agonists (SABAs) have also been widely used for symptom relief. However, SABAs have been reported to increase the risk of asthma-related death, though incidences have been very rare. Consequently, a dilemma exists regarding recommendation of a SABA alone without an ICS or a controller to asthma patients even with very mild disease. In the real world, asthma patients tend to intermittently use ICS and more likely to be dependent on SABA since many patients want immediate relief of their symptoms. Consequently, a dilemma exists regarding the underuse of ICSs but the overuse of SABAs. One strategy for solving the presented dilemma would be identification of patients with asthma who require persistent use of asthma controllers. Such patients, who may be referred to as “persistent controller users,” should continuously receive ICSs, even under controlled states of asthma. Another strategy would be a patient-adjusted, symptom-driven, intermittent-toregular treatment combining low-dose ICS/rapid-onset long-acting β-agonists instead of using a SABA alone or with lowdose ICS for the asthma patients with mild disease. Both of these two strategies could avoid the risky treatment of a SABA alone without an ICS and could reduce the dose of ICS with the maintenance of asthma control.

Dilemma of Asthma Treatment in Mild Patients

Cho, You Sook,Oh, Yeon-Mok The Korean Academy of Tuberculosis and Respiratory 2019 Tuberculosis and Respiratory Diseases Vol.82 No.3

Inhaled corticosteroids (ICSs) have been widely used as a key medication for asthma control. However, ICSs have been known to cause respiratory infections, such as pneumonia and pulmonary tuberculosis. Consequently, a dilemma exists regarding recommendation of persistent lifetime use of ICSs to mild asthma patients. Short-acting ${\beta}$-agonists (SABAs) have also been widely used for symptom relief. However, SABAs have been reported to increase the risk of asthma-related death, though incidences have been very rare. Consequently, a dilemma exists regarding recommendation of a SABA alone without an ICS or a controller to asthma patients even with very mild disease. In the real world, asthma patients tend to intermittently use ICS and more likely to be dependent on SABA since many patients want immediate relief of their symptoms. Consequently, a dilemma exists regarding the underuse of ICSs but the overuse of SABAs. One strategy for solving the presented dilemma would be identification of patients with asthma who require persistent use of asthma controllers. Such patients, who may be referred to as "persistent controller users," should continuously receive ICSs, even under controlled states of asthma. Another strategy would be a patient-adjusted, symptom-driven, intermittent-to-regular treatment combining low-dose ICS/rapid-onset long-acting ${\beta}$-agonists instead of using a SABA alone or with low-dose ICS for the asthma patients with mild disease. Both of these two strategies could avoid the risky treatment of a SABA alone without an ICS and could reduce the dose of ICS with the maintenance of asthma control.

만성폐쇄성기도질환의 최적 치료를 위한 정밀의학적 접근

조유숙 ( You Sook Cho ) 대한천식알레르기학회(구 대한알레르기학회) 2018 Allergy Asthma & Respiratory Disease Vol.6 No.3

Bronchial asthma and chronic obstructive pulmonary disease (COPD) are 2 representative diseases of chronic obstructive inflammatory airway diseases, and both show a wide range of heterogeneity in their clinical features. Although one end of typical asthma and the other end of COPD are clearly different, both diseases share lots of similarities in biological aspects and clinical manifestations. Currently, 2 different guidelines exist for asthma and COPD management, respectively, and in many clinical situations it is not easy to manage patients especially who have both features and show refractoriness to available medications. Since the features of the diseases are remarkably diverse in terms of clinical courses, prognosis and responses to therapeutic drugs, there have been vigorous efforts to classify appropriate subtypes in order to improve management of the diseases. However, dichotomous thinking about asthma and COPD precludes precise classification of the diseases in the real world. In this article, thus, chronic obstructive airway disease (COAD) ranging from asthma particularly in adults to COPD is proposed as 1 target subject to analyze precise classification based on exact phenotyping and endotyping of the diseases. In the current article, the reasonable precision medicine approach is also suggested based on treatable traits of COAD to achieve the best treatment for COAD patients. (Allergy Asthma Respir Dis 2018;6:141-148)

중증난치성 천식의 정의

조유숙 ( You Sook Cho ) 대한내과학회 2012 대한내과학회지 Vol.83 No.4

Severe refractory asthma is a group of asthmatic patients showing heterogeneous phenotypes with frequent exacerbations and progressive airway remodeling despite high levels of therapy. Studies of severe asthma is difficult not only because of diverse pathogenesis, difficulty in translating pre-clinical human and animal models to clinical trials, and absence of biomarkers that predict therapeutic efficacy but because of lack of consensus on precise definition and diagnostic criteria of severe asthma. Furthermore, the burden of severe asthma is considerably high, therefore, there has been an urgent need for researching strategies to overcome severe asthma. In conclusion, precise characterization, exact definition, and appropriate classification of severe asthma would be critical to improve management of this challenging disease and these efforts could help to develop novel therapeutic strategies. (Korean J Med 2012;83:417-423)

성인 급성 림프구성 백혈병의 예후 : - 33 예의 환자들을 대상으로 한 분석 -

조유숙(You Sook Cho),이규형(Kyoo Hyung Lee),이제환(Je Hwan Lee),김성배(Sung Bae Kim),김상위(Sang We Kim),서철원(Cheol Won Suh),이정신(Jung Shin Lee),김우건(Woo Kun Kim),김상희(Sang Hee Kim),지현숙(Hyun Sook Chi),박찬정(Chan Jung Park 대한내과학회 1997 대한내과학회지 Vol.52 No.3

N/A Objectives: Rate of complete remission and long-term survival in adult acute lymphoblastic leukemia group has not been as satisfactory as that in childhood ALL. Recently introduction of induction chemotherapy of more intensive combination and various trials of postremission therapy are making improved results better looked forward to. And subtypes of ALL according to the degree of differentiation into T and B cells are identified by using immunologic markers hopefully to work out proper treatment for each subtype. Methods: We analited results of treatment and differences of complete remission rate, remission duration and overall survival as to various immunologic markers and clinicopathologic characteristics in 33adult ALL patients. Results: Eighty five percents of the 27cases that had VPDL chemotherapy achieved complete remission and both overall median survival and mediom duration of remission were 52weeks. No definite prognostic factors were detected influencing complete remission rate, remission duration and overall survival except that patients with serum albumin level higher than 4.0mg/dL showed highter complete remission rate. Although mature B-ALL showed the shortest overall median survival, degree of differenciation of B-cell and other immunologic markers did not influence on complete remission rate, remission duration or overall survival. Conclusion: Further studies are needed to delire the prognostic factors in adult ALL

췌장두부암으로 오인된 간외 문맥류 1 예

조광희(Kwang Hee Cho),조상형(Sang Hyung Cho),조현호(Hyun Ho Cho),최대현(Dae Hyun Choi),한철주(Chul Ju Han),김진(Jin Kim),정숙향(Sook Hyang Jung),이병희(Byung Hee Lee),김영호(Young Ho Kim),정진모(Jin Mo Jung),김유철(You Choul Kim),이진 대한소화기학회 2002 대한소화기학회지 Vol.39 No.2

Reports of portal vein aneurysm are scattered in the literature. However, with the increased use of sonography, CT, MRI, it is found incidentally with greater frequency. Clinical presentation ranges from without symptom to hemobilia, hemoperitoneum, thrombosis, compression of adjacent structures, and spontaneous arteriovenous fistula. Sometimes, it is confused with a pancreatic head mass, raising a diagnostic problem. We report a case of extrahepatic portal vein aneurysm confused with pancreatic head cancer. A 45-year-old woman presented with weight loss of 10 kg, and ultrasonography and CT revealed a pancreatic head mass. Laparotomy was performed, but resection of the mass was impossible. Later review of the enhanced spiral CT and angiography revealed that the mass actually represented a portal vein aneurysm. Her condition has remained stable with just clinical observation. Portal vein aneurysm should be considered when there is an enhancing mass adjacent to the portal vein or superior mesenteric vein. (Korean J Gastroenterol 2002;39:137-141)